SHIMONOSONO Masataka 下之薗将貴

… Alternative Names

Shimonosono Masataka 下之薗将貴

下之薗将貴シモノソノマサタカ

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Researcher Number	40814322
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 助教
Affiliation (based on the past Project Information) *help	2024: 鹿児島大学, 医歯学域医学系, 助教 2021 – 2024: 鹿児島大学, 鹿児島大学病院, 医員 2018: 鹿児島大学, 附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / 0901:Oncology and related fields Except Principal Investigator Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator 食道扁平上皮癌 / オルガノイド / 食道癌 / 薬剤スクリーニング / 発癌 / オルガノイド培養 / 遺伝子プロファイル / 薬剤感受性試験 / 遺伝子解析 Except Principal Investigator ゲノム … More / 膵癌 / 消化器癌治療耐性因子 / ATAC-seq / 消化器癌 / クロマチン変化 / 遺伝子変異 / リスク低減 / マイクロバーオーム / 胃癌 / リキッドバイオプシー診断 / マイクロ流体チップ / オルガノイド / コンパニオン診断 / ポリマーCTCチップ / Circulating Tumor Cell / 循環腫瘍細胞 / リキッドバイオプシー / マイクロバイオータ / IPMN / 細菌叢 / マイクロバイオ―タ / 早期診断 / 発癌 Less

Would comprehensive analyses of genome and microbiome establish the strategy for decreasing the risk of pancreatic cancer?
- Principal Investigator
  
  大塚隆生
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kagoshima University
High-throughput drug screening realize a precision medicine for esophageal cancerPrincipal Investigator
- Principal Investigator
  
  下之薗将貴
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kagoshima University
クロマチン変化の時間軸に着目した消化器癌治療耐性因子の解明
- Principal Investigator
  
  喜多芳昭
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kagoshima University
Liquid Biopsy Diagnosis Using Microfluidic Chip Technology Revolutionizes Gastric Cancer Treatment
- Principal Investigator
  
  有上貴明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kagoshima University
Why does whole pancreas become risk zone for cancer development? Assessment of microbiota and the challenge for early diagnosis of pancreatic cancer.
- Principal Investigator
  
  Ohtsuka Takao
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kagoshima University
Esophageal cancer organoid culture leads to the developement of new drug to prevent the occurrence of cancerPrincipal Investigator
- Principal Investigator
  
  Shimonosono Masataka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kagoshima University
食道扁平上皮癌オルガノイド・マイクロRNA解析による治療抵抗性分子経路の解明Principal Investigator
- Principal Investigator
  
  下之薗将貴
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kagoshima University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Prognostic impact of clinical trial eligibility in patients with advanced gastric cancer2025
- Author(s)
  Arigami Takaaki、Matsushita Daisuke、Shimonosono Masataka、Hirase Yuki、Tsuruda Yusuke、Sasaki Ken、Baba Kenji、Kawasaki Yota、Ohtsuka Takao
- Journal Title
  
  Scientific Reports
  
  Volume: 15 Issue: 1 Pages: 10961-10961
- DOI
  10.1038/s41598-025-95501-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16453, KAKENHI-PROJECT-23K08198
[Journal Article] Clinical Significance of Body Weight Loss During Chemotherapy for Advanced Gastric Cancer Undergoing Conversion Surgery2024
- Author(s)
  Arigami T, Matsushita D, Shimonosono M, Hirase Y, Tsuruda Y, Sasaki K, Baba K, Ohtsuka T
- Journal Title
  
  Anticancer Research
  
  Volume: 44 Issue: 9 Pages: 4031-4037
- DOI
  10.21873/anticanres.17232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08198
[Journal Article] Modeling Epithelial Homeostasis and Perturbation in Three-Dimensional Human Esophageal Organoids2024
- Author(s)
  Shimonosono Masataka, Nakagawa Hiroshi
- Journal Title
  
  Biomolecules
  
  Volume: 14 Issue: 9 Pages: 1126-1126
- DOI
  10.3390/biom14091126
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11892
[Journal Article] Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-132024
- Author(s)
  Masuda Mia Y.、Shimonosono Masataka、Flashner Samuel、Morimoto Masaki、Pai Rish K.、Rank Matthew A.、Nakagawa Hiroshi、Kita Hirohito、Wright Benjamin L.、Doyle Alfred D.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: - Issue: 5 Pages: 1355-1368
- DOI
  10.1016/j.jaci.2024.01.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20842
[Journal Article] Evaluation of Quality of Life and Prognosis of Gastric Cancer Patients After Laparoscopic Subtotal Gastrectomy2023
- Author(s)
  SHIMONOSONO MASATAKA、ARIGAMI TAKAAKI、MATSUSHITA DAISUKE、TSURUDA YUSUKE、SASAKI KEN、BABA KENJI、UCHIKADO YASUTO、KURAHARA HIROSHI、OHTSUKA TAKAO
- Journal Title
  
  Anticancer Research
  
  Volume: 44 Issue: 1 Pages: 387-396
- DOI
  10.21873/anticanres.16823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K20842
[Journal Article] ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment2023
- Author(s)
  Flashner Samuel、Shimonosono Masataka、Tomita Yasuto、Matsuura Norihiro、Ohashi Shinya、Muto Manabu、Klein-Szanto Andres J、Alan Diehl J、Chen Che-Hong、Mochly-Rosen Daria、Weinberg Kenneth I、Nakagawa Hiroshi
- Journal Title
  
  Carcinogenesis
  
  Volume: 45 Issue: 1-2 Pages: 95-106
- DOI
  10.1093/carcin/bgad085
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20842, KAKENHI-PROJECT-22K07960
[Journal Article] CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis2022
- Author(s)
  Takeo Hara, Yuta Kasagi, Joshua Wang, Masaru Sasaki, Bailey Aaron, Adam Karami, Masataka Shimonosono, Rieko Shimonosono, Hisatsugu Maekawa, Lauren Dolinsky, Benjamin Wilkins, Jeremy Klein, Jane Wei, Kathryn Nunes, Kristle Lynch, Kathryn E Hamilton, Tatiana A Karakasheva, Kelly A Whelan, Hiroshi Nakagawa, Amanda B Muir
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 13 Issue: 5 Pages: 1449-1467
- DOI
  10.1016/j.jcmgh.2022.01.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20842
[Journal Article] MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma2021
- Author(s)
  Angela J Yoon, Regina M Santella, Shuang Wang, David I Kutler, Richard D Carvajal, Elizabeth Philipone, Tian Wang, Scott M Peters, Claire R Stewart, Fatemeh Momen-Heravi, Scott Troob, Matt Levin, Zohreh AkhavanAghdam, Austin J Shackelford, Carleigh R Canterbury, Masataka Shimonosono, Hiroshi Nakagawa
- Journal Title
  
  Journal of Oncology
  
  Volume: 2021 Pages: 1-11
- DOI
  10.1155/2021/8292453
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20842
[Journal Article] Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy2021
- Author(s)
  Shimonosono Masataka、Tanaka Koji、Flashner Samuel、Takada Satoshi、Matsuura Norihiro、Tomita Yasuto、Sachdeva Uma M.、Noguchi Eishi、Sangwan Veena、Ferri Lorenzo、Momen-Heravi Fatemeh、Yoon Angela J.、Klein-Szanto Andres J.、Diehl J. Alan、Nakagawa Hiroshi
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 10 Pages: 1479-1479
- DOI
  10.3390/biom11101479
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20842
[Journal Article] Understanding the cellular origin and progression of esophageal cancer using esophageal organoids2021
- Author(s)
  Sachdeva Uma M.、Shimonosono Masataka、Flashner Samuel、Cruz-Acuna Ricardo、Gabre Joel T.、Nakagawa Hiroshi
- Journal Title
  
  Cancer Letters
  
  Volume: 509 Pages: 39-52
- DOI
  10.1016/j.canlet.2021.03.031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20842
[Journal Article] Clinical impact of creatine phosphokinase and c-reactive protein as predictors of postgastrectomy complications in patients with gastric cancer2021
- Author(s)
  Okubo Keishi、Arigami Takaaki、Matsushita Daisuke、Kijima Takashi、Shimonosono Masataka、Uenosono Yoshikazu、Yanagita Shigehiro、Kurahara Hiroshi、Mori Shinichiro、Ohtsuka Takao、Natsugoe Shoji
- Journal Title
  
  BMC Cancer
  
  Volume: 21 Issue: 1 Pages: 95-95
- DOI
  10.1186/s12885-021-07801-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20842
[Presentation] 実臨床におけるstage IV胃癌に対する治療戦略―Conversion Surgeryの臨床的意義も含めて―2025
- Author(s)
  有上貴明, 松下大輔, 下之薗将貴, 平瀬雄規, 鶴田祐介, 佐々木健, 馬場研二, 大塚隆生
- Organizer
  第125回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23K08198
[Presentation] ICI登場は切除不能進行・再発胃癌に対する化学療法戦略の変化や予後に影響を与えたのか？2024
- Author(s)
  有上貴明, 松下大輔, 下之薗将貴, 平瀬雄規, 鶴田祐介, 佐々木健, 大塚隆生
- Organizer
  第32回日本消化器関連学会週間 (JDDW)
- Data Source
  KAKENHI-PROJECT-23K08198
[Presentation] 切除不能進行胃癌に対するconversion surgeryの適応とは？―組織学的効果予測の観点から―2024
- Author(s)
  有上貴明, 松下大輔, 下之薗正将貴, 鶴田祐介, 佐々木健, 和田真澄,黒島直樹, 馬場研二, 大塚隆生
- Organizer
  第79回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-23K08198
[Presentation] Clinical Significance of Conversion Surgery as a Sequential Therapeutic Strategy in Patients with Unresectable Gastric Cancer2024
- Author(s)
  Takaaki Arigami, Daisuke Matsushita, Masataka Shimonosono, Yusuke Tsuruda, Ken Sasaki, Masumi Wada, Naoki Kuroshima, Kenji Baba, Takao Ohtsuka
- Organizer
  第62回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08198
[Presentation] アルコール暴露は頭頸部・食道癌腫瘍内でオートファジー活性の高い癌幹細胞分画の増加を誘導する2022
- Author(s)
  下之薗将貴
- Organizer
  日本外科学会総会
- Data Source
  KAKENHI-PROJECT-21K20842

1. Ohtsuka Takao (20372766)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. 関直彦 (50345013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 谷本昭英 (10217151)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 杉浦剛 (40322292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 松下大輔 (10724205)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 田上聖徳 (50721031)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 夏越祥次 (70237577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 蔵原弘 (70464469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 有上貴明 (40527058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 大永崇 (10416133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中嶋太極 (30974646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 井手野昇 (90883421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 喜多芳昭 (30570692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 馬場研二 (30642615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 鶴田祐介 (70812767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 和田真澄 (60836112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 川崎洋太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMONOSONO Masataka 下之薗 将貴

Shimonosono Masataka 下之薗 将貴

下之薗 将貴 シモノソノ マサタカ

Research Projects

Research Products

Co-Researchers

Would comprehensive analyses of genome and microbiome establish the strategy for decreasing the risk of pancreatic cancer?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

High-throughput drug screening realize a precision medicine for esophageal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

クロマチン変化の時間軸に着目した消化器癌治療耐性因子の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Liquid Biopsy Diagnosis Using Microfluidic Chip Technology Revolutionizes Gastric Cancer Treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Why does whole pancreas become risk zone for cancer development? Assessment of microbiota and the challenge for early diagnosis of pancreatic cancer.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Esophageal cancer organoid culture leads to the developement of new drug to prevent the occurrence of cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

食道扁平上皮癌オルガノイド・マイクロRNA解析による治療抵抗性分子経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Prognostic impact of clinical trial eligibility in patients with advanced gastric cancer2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical Significance of Body Weight Loss During Chemotherapy for Advanced Gastric Cancer Undergoing Conversion Surgery2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modeling Epithelial Homeostasis and Perturbation in Three-Dimensional Human Esophageal Organoids2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-132024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of Quality of Life and Prognosis of Gastric Cancer Patients After Laparoscopic Subtotal Gastrectomy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis2022

Author(s)

SHIMONOSONO Masataka 下之薗将貴

Shimonosono Masataka 下之薗将貴

下之薗将貴シモノソノマサタカ