Ohshima Kenji 大島健司

Researcher Number	40817152
Other IDs	https://orcid.org/0000-0003-1114-386X
Affiliation (Current)	2024: 兵庫医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023: 兵庫医科大学, 医学部, 教授 2019 – 2021: 大阪大学, 医学系研究科, 助教 2018: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / 0901:Oncology and related fields
Keywords	Principal Investigator 大腸がん / 転移 / 腫瘍代謝 / ヒストンアセチル化 / ミトコンドリア / がん代謝 / 化学療法抵抗性 / がん浸潤 / D-glutamate cyclase / 代謝 … More / 浸潤 / C14orf159 / 癌代謝 / アミノ酸 / アポトーシス / 活性酸素 / セリンラセマーゼ / ピルビン酸 Less

Deciphering the metabolic determinants of colorectal cancer metastasisPrincipal Investigator
- Principal Investigator
  
  大島健司
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Hyogo Medical University
Function of D-glutamate cyclase in colorectal cancer metabolismPrincipal Investigator
- Principal Investigator
  
  Ohshima Kenji
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Osaka University
Regulation of cancer metabolism by D-amino acids or the enzymes which metabolize D-amino acidsPrincipal Investigator
- Principal Investigator
  
  Ohshima Kenji
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Osaka University

All 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] 実験医学2020
- Author(s)
  大島健司、森井英一
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18K15122
[Journal Article] Mitochondria govern histone acetylation in colorectal cancer2021
- Author(s)
  Ohshima Kenji、Oi Ryo、Nojima Satoshi、Morii Eiichi
- Journal Title
  
  The Journal of Pathology
  
  Volume: 256 Issue: 2 Pages: 164-173
- DOI
  10.1002/path.5818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16220, KAKENHI-PROJECT-19H03452
[Journal Article] がん細胞特異的代謝を標的とした治療戦略2021
- Author(s)
  大島健司、森井英一
- Journal Title
  
  Precision Medicine
  
  Volume: 4 Pages: 1202-1205
- Data Source
  KAKENHI-PROJECT-20K16220
[Journal Article] Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling2021
- Author(s)
  Ohshima Kenji、Oi Ryo、Okuzaki Daisuke、Motooka Daisuke、Shinohara Masakazu、Nojima Satoshi、Morii Eiichi
- Journal Title
  
  British Journal of Cancer
  
  Volume: 125 Issue: 12 Pages: 1699-1711
- DOI
  10.1038/s41416-021-01582-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16220, KAKENHI-PROJECT-19H03452
[Journal Article] Metabolic Reprogramming of Cancer Cells during Tumor Progression and Metastasis.2021
- Author(s)
  Ohshima K, Morii E.
- Journal Title
  
  Metabolites.
  
  Volume: 11 Issue: 1 Pages: 28-28
- DOI
  10.3390/metabo11010028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03452, KAKENHI-PROJECT-20K16220
[Journal Article] Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine2020
- Author(s)
  Kenji Ohshima, Satoshi Nojima, Shinichiro Tahara, Masako Kurashige, Keisuke Kawasaki, Yumiko Hori, Moyu Taniguchi, Yutaka Umakoshi, Daisuke Okuzaki, Naoki Wada, Jun-ichiro Ikeda, Eiichiro Fukusaki & Eiichi Morii
- Journal Title
  
  Nature Metabolism volume
  
  Volume: 2 Issue: 1 Pages: 81-96
- DOI
  10.1038/s42255-019-0156-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19555, KAKENHI-PROJECT-18K15122, KAKENHI-PROJECT-19K16557, KAKENHI-PROJECT-19K16585
[Presentation] Serine racemase promotes colorectal cancer growth and is a new therapeutic target for colorectal cancer2021
- Author(s)
  大島健司
- Organizer
  Manchester Pathology 2021 (英国病理学会)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16220
[Presentation] 大腸がんの増殖と転移を司る新たな代謝酵素群2021
- Author(s)
  大島健司
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16220
[Presentation] ミトコンドリア局在タンパク質C14orf159の大腸がん細胞の浸潤・転移における機能2021
- Author(s)
  大島健司
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K16220
[Presentation] c14orf159 loss facilitates colorectal cancer cell invasion through upregulates Wnt signaling2020
- Author(s)
  大島健司
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16220
[Presentation] Serine racemase enhances colon cancer cell proliferation by maintaining mitochondrial mass2019
- Author(s)
  大島健司
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15122
[Presentation] Serine racemaseは細胞内ピルビン酸量を維持し大腸癌の増殖を促進する2019
- Author(s)
  大島健司
- Organizer
  第7回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-18K15122
[Presentation] Serine racemaseはセリンからピルビン酸を産生し大腸癌の増殖を促進する2019
- Author(s)
  大島健司
- Organizer
  第2回医学系研究科・産業科学研究所懇話会
- Data Source
  KAKENHI-PROJECT-18K15122
[Presentation] Serine racemase is a potential new therapeutic target for colon cancer2018
- Author(s)
  大島健司
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15122
[Presentation] Serine racemase is a new therapeutic target for colon cancer2018
- Author(s)
  大島健司
- Organizer
  American Association for Cancer Research Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15122
[Presentation] D-セリン合成酵素 Serine racemase は大腸癌細胞の増殖を促進する2018
- Author(s)
  大島健司
- Organizer
  第15回日本病理学会カンファレンス
- Data Source
  KAKENHI-PROJECT-18K15122

1. 森井英一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ohshima Kenji 大島 健司

Research Projects

Research Products

Co-Researchers

Deciphering the metabolic determinants of colorectal cancer metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Function of D-glutamate cyclase in colorectal cancer metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of cancer metabolism by D-amino acids or the enzymes which metabolize D-amino acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 実験医学2020

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Mitochondria govern histone acetylation in colorectal cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] がん細胞特異的代謝を標的とした治療戦略2021

Author(s)

Journal Title

Data Source

[Journal Article] Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic Reprogramming of Cancer Cells during Tumor Progression and Metastasis.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Serine racemase promotes colorectal cancer growth and is a new therapeutic target for colorectal cancer2021

Author(s)

Organizer

Data Source

[Presentation] 大腸がんの増殖と転移を司る新たな代謝酵素群2021

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリア局在タンパク質C14orf159の大腸がん細胞の浸潤・転移における機能2021

Author(s)

Organizer

Data Source

[Presentation] c14orf159 loss facilitates colorectal cancer cell invasion through upregulates Wnt signaling2020

Author(s)

Organizer

Data Source

[Presentation] Serine racemase enhances colon cancer cell proliferation by maintaining mitochondrial mass2019

Author(s)

Organizer

Data Source

[Presentation] Serine racemaseは細胞内ピルビン酸量を維持し大腸癌の増殖を促進する2019

Author(s)

Organizer

Data Source

[Presentation] Serine racemaseはセリンからピルビン酸を産生し大腸癌の増殖を促進する2019

Author(s)

Organizer

Data Source

[Presentation] Serine racemase is a potential new therapeutic target for colon cancer2018

Ohshima Kenji 大島健司