Hirano Masaki 平野雅規

Researcher Number	40823076
Affiliation (based on the past Project Information) *help	2020 – 2022: 愛知県がんセンター(研究所), 分子腫瘍学分野, 研修生 2019: 名古屋大学, 医学系研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 悪性脳腫瘍 / ChIP-seq / miRNA / NGS / 髄膜腫 / 悪性神経膠腫 / スーパーエンハンサー / オルガノイド / 膠芽腫 / エンハンサー … More / 化学療法抵抗性 / エピジェネティクス / アクティブエンハンサー / RNA-seq / cis-regulatory element / RFP / 化学療法耐性 / 神経膠芽腫 / chemoresistance / epigenetics / active cis-element / RET finger protein / glioblastoma … More Except Principal Investigator 悪性脳腫瘍 / エピゲノム異常 / 染色体構造異常 / マウスモデル / シングルセル解析 / ポドプラニン / キメラ抗原受容体T細胞 / 細胞免疫療法 / ネオアンチゲン / 脳腫瘍 Less

スーパーエンハンサーとmiRNAの統合解析による悪性神経膠腫の新規治療標的探索Principal Investigator
- Principal Investigator
  
  平野雅規
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Aichi Cancer Center Research Institute
Mechanism of chemoresistance in malignant gliomas via active enhancersPrincipal Investigator
- Principal Investigator
  
  Hirano Masaki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Aichi Cancer Center Research Institute
  Nagoya University
Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formation
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University

All 2022 2021 2020 2019 Other

All Journal Article Presentation Other

[Journal Article] Electron-transfer kinetics through nucleic acids untangled by single-molecular fluorescence blinking2022
- Author(s)
  Fan Shuya、Xu Jie、Osakada Yasuko、Hashimoto Katsunori、Takayama Kazuya、Natsume Atsushi、Hirano Masaki、Maruyama Atsushi、Fujitsuka Mamoru、Kawai Kumi、Kawai Kiyohiko
- Journal Title
  
  Chem
  
  Volume: 8 Issue: 11 Pages: 3109-3119
- DOI
  10.1016/j.chempr.2022.07.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02059, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356
[Journal Article] Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds2021
- Author(s)
  Kitano Yotaro、Aoki Kosuke、Ohka Fumiharu、Yamazaki Shintaro、Motomura Kazuya、Tanahashi Kuniaki、Hirano Masaki、Naganawa Tsuyoshi、Iida Mikiko、Shiraki Yukihiro、Nishikawa Tomohide、Shimizu Hiroyuki、Yamaguchi Junya、Maeda Sachi、Suzuki Hidenori、Wakabayashi Toshihiko、Baba Yoshinobu、Yasui Takao、Natsume Atsushi
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13 Issue: 15 Pages: 17316-17329
- DOI
  10.1021/acsami.1c01754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21124, KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-19KK0228
[Journal Article] Newly established patient-derived organoid model of intracranial meningioma2021
- Author(s)
  Yamazaki Shintaro、Ohka Fumiharu、Hirano Masaki、Shiraki Yukihiro、Motomura Kazuya et al
- Journal Title
  
  Neuro-Oncology
  
  Volume: 23 Issue: 11 Pages: 1936-1948
- DOI
  10.1093/neuonc/noab155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-21K16645, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-20H03511, KAKENHI-PROJECT-20J01889, KAKENHI-PROJECT-20K20598
[Journal Article] H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant.2020
- Author(s)
  Maeda S, Ohka F, Okuno Y, Aoki K, Motomura K, Takeuchi K, Kusakari H, Yanagisawa N, Sato S, Yamaguchi J, Tanahashi K, Hirano M, Kato A, Shimizu H, Kitano Y, Yamazaki S, Yamashita S, Takeshima H, Shinjo K, Kondo Y, Wakabayashi T, Natsume A.
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 8 Issue: 1 Pages: 8-19
- DOI
  10.1186/s40478-020-0882-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09478, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17K16643, KAKENHI-PROJECT-17K17792, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-20K20598
[Journal Article] Neurocognitive and functional outcomes in patients with diffuse frontal lower-grade gliomas undergoing intraoperative awake brain mapping.2019
- Author(s)
  Motomura K, Chalise L, Ohka F, Aoki K, Tanahashi K, Hirano M, Nishikawa T, Yamaguchi J, Shimizu H, Wakabayashi T, Natsume A.
- Journal Title
  
  J Neurosurg.
  
  Volume: 17 Issue: 6 Pages: 1-9
- DOI
  10.3171/2019.3.jns19211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-19KK0228, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-18H02911
[Journal Article] Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide2019
- Author(s)
  NATSUME Atsushi、HIRANO Masaki、RANJIT Melissa、AOKI Kosuke、WAKABAYASHI Toshihiko
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 59 Issue: 8 Pages: 293-298
- DOI
  10.2176/nmc.ra.2019-0049
- NAID
  130007690186
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] RET finger protein阻害に関連したactive cis-regulatory elementsの変化により、神経膠芽腫の化学療法抵抗性が改善される2020
- Author(s)
  平野　雅規、メリッサ　ランジット、青木　恒介、奥野　友介、大岡　史治、山道　茜、前田　紗知、加藤　彰、本村　和也、松尾　恵太郎、榎本　篤、稲生　靖、藤堂　具紀、高橋　雅英、若林　俊彦、加藤　琢哉、夏目　敦至
- Organizer
  第１回癌学会若手の会
- Data Source
  KAKENHI-PROJECT-19K18386
[]

1. Natsume Atsushi (30362255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 大岡史治 (10725724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 青木恒介 (10759773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 加藤彰 (50793056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YASUI Takao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 川井清彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 本村和也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hirano Masaki 平野 雅規

Research Projects

Research Products

Co-Researchers

スーパーエンハンサーとmiRNAの統合解析による悪性神経膠腫の新規治療標的探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of chemoresistance in malignant gliomas via active enhancersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Electron-transfer kinetics through nucleic acids untangled by single-molecular fluorescence blinking2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Newly established patient-derived organoid model of intracranial meningioma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurocognitive and functional outcomes in patients with diffuse frontal lower-grade gliomas undergoing intraoperative awake brain mapping.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] RET finger protein阻害に関連したactive cis-regulatory elementsの変化により、神経膠芽腫の化学療法抵抗性が改善される2020

Author(s)

Organizer

Data Source

[]

Hirano Masaki 平野雅規