NISHII NAOTO 西井直人

… Alternative Names

Nishii Naoto 西井直人

Less

Researcher Number	40836285
Other IDs
Affiliation (Current)	2025: 東京科学大学, 東京科学大学病院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 東京医科歯科大学, 東京医科歯科大学病院, 助教 2021: 東京医科歯科大学, 歯学部附属病院, 特任助教 2019 – 2020: 地方独立行政法人山梨県立病院機構山梨県立中央病院(がんセンター局ゲノム解析センター), ゲノム解析センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 好中球リンパ球比 / 免疫プロファイル / PD-1阻害抗体 / 遺伝子変異プロファイル / 多重免疫染色 / 腫瘍免疫 / PD-L1 / バイオマーカー / 好中球リンパ球比率 / ニボルマブ / 免疫チェックポイント阻害剤 / 癌免疫プロファイル / 口腔癌 … More Except Principal Investigator … More 口腔扁平苔癬 / 免疫 / 免疫チェックポイント阻害薬 / 免疫プロファイル / がん微小環境 / がん免疫 / 口腔癌 Less

口腔扁平苔癬の病勢指標となるバイオマーカーの探索
- Principal Investigator
  
  津島文彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Medical and Dental University
口腔癌の抗PD-1抗体治療効果を予測する、免疫応答を多角的に捉えた新規評価系樹立Principal Investigator
- Principal Investigator
  
  西井直人
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Tokyo Medical and Dental University
Proposal of multidisciplinary approach based on immune profiling in oral cancer
- Principal Investigator
  
  Azuma Miyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of the immunosuppressive mechanism of oral cancer to identify the patients who respond to nivolumabPrincipal Investigator
- Principal Investigator
  
  Nishii Naoto
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Tokyo Medical and Dental University
  Yamanashi Prefectural Hospital Organization

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence2023
- Author(s)
  Daroonpan Pissacha、Ouchi Ryo、Zhang Chenyang、Nagai Shigenori、Nishii Naoto、Kashima Yoshihisa、Tsushima Fumihiko、Harada Hiroyuki、Hamagaki Miwako、Ikeda Tohru、Aida Jun、Kaomongkolgit Ruchadaporn、Azuma Miyuki
- Journal Title
  
  Oral Oncology
  
  Volume: 143 Pages: 106458-106458
- DOI
  10.1016/j.oraloncology.2023.106458
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06593, KAKENHI-PROJECT-21H03138
[Journal Article] Observation of dynamic changes in neutrophil-to-lymphocyte ratio is useful for evaluating treatment response to nivolumab in PD-L1-negative advanced oral cancer2022
- Author(s)
  Naoto Nishii, Yosuke Hirotsu, Yukinobu Takahashi, Yuki Takagawa, Kenji Amemiya, Toshio Oyama, Hitoshi Mochizuki, Emi Furusawa-Nishii, Hiroyuki Harada, Masao Omata
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: 34 Pages: 833-841
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18959
[Journal Article] Discrepancy Between Clinical Diagnosis and Whole-exome Sequencing-based Clonality Analysis of Synchronous Multiple Oral Cancers2021
- Author(s)
  NISHII NAOTO、HIROTSU YOSUKE、KOIDA NAMI、TAKAHASHI YUKINOBU、TAKAGAWA YUKI、AMEMIYA KENJI、OYAMA TOSHIO、MOCHIZUKI HITOSHI、FURUSAWA-NISHII EMI、HARADA HIROYUKI、OMATA MASAO
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 2 Pages: 1035-1040
- DOI
  10.21873/anticanres.14859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18959, KAKENHI-PROJECT-20H03668
[Journal Article] Renal cell carcinoma metastasis to the maxillary bone successfully treated with surgery after vascular embolization: a case report2020
- Author(s)
  Nishii Naoto、Shimamoto Hiroaki、Ohsako Toshimitsu、Yokokawa Misaki、Sato Yuriko、Ohata Yae、Kayamori Kou、Ikeda Tohru、Harada Hiroyuki
- Journal Title
  
  Journal of Medical Case Reports
  
  Volume: 14 Issue: 1
- DOI
  10.1186/s13256-020-02522-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18959
[Presentation] Personal immune profiles of oral tongue squamous cell carcinoma -Part 1: Analyses of 87 cases of surgical specimens and immune subtype classification2024
- Author(s)
  Yuya Su, Ryo Ouchi, Pissacha Daroonpan, Naoto Nishii, Hiroyuki Harada, Tohru Ikeda, Jun Aida, Miyuki Azuma
- Organizer
  The 1st International Symposium on Cancer Immunology and Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] Personal immune profiles of oral tongue squamous cell carcinoma -Part 2: Analyses of the patients treated with PD-1 immune checkpount inhibitors-2024
- Author(s)
  Ryo Ouchi, Yuya Su, Pissacha Daroonpan, Naoto Nishii, Hiroyuki Harada, Tohru Ikeda, Jun Aida, Miyuki Azuma
- Organizer
  The 1st International Symposium on Cancer Immunology and Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] 舌扁平上皮癌のパーソナル免疫プロファイル-包括的免疫パラメーター解析と予後予測-2023
- Author(s)
  Pissacha Daroonpan, Ryo Ouchi, Naoto Nishii, Fumihiko Tsushima, Hiroyuki Harada, Miyuki Azuma
- Organizer
  第82 回日本癌学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] 舌扁平上皮癌における PD-1 免疫チェックポイント阻害剤投与症例の免疫プロファイリング解析2023
- Author(s)
  大内崚、ダルンパン　ピサッチャー、野地理夏、加納嘉人、西井直人、野口誠、濱垣美和子、池田通、原田浩之、東みゆき、
- Organizer
  第77回　日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18959
[Presentation] 舌扁平上皮癌における PD-1 免疫チェックポイント阻害剤投与症例の免疫プロファイリング解析2023
- Author(s)
  大内　陵，ダルンパン　ピサッチャー，野地　理夏、加納　嘉人、西井　直人，津島　文彦，原田　浩之，東　みゆき
- Organizer
  第77回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] 肉眼分類とがん浸潤様式からみた舌扁平上皮癌の免疫プロファイルの多様性2022
- Author(s)
  ダルーンパン　ピサッチャー、西井直人、加島義久、濱垣　美和子、津島　文彦、原田　浩之、池田　通、東みゆき
- Organizer
  第76 回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] Comprehensive analyses between clinical outcome and immunopathological profiles in tongue SCC2022
- Author(s)
  ダルンパン　ピサッチャー，西井　直人，津島　文彦，原田　浩之，東　みゆき
- Organizer
  第81回日本癌学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] 肉眼分類とがん浸潤様式から見た舌扁平上皮癌の免疫プロファイルの多様性2022
- Author(s)
  ダルンパン　ピサッチャー，西井　直人，加島　義久，濱崎　美和子，津島　文彦，原田　浩之，池田　通，東　みゆき
- Organizer
  第76回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] PD-1阻害抗体：Nivolumab投与効果を予測する新規評価系樹立の取り組み2021
- Author(s)
  西井直人、髙川祐樹、髙橋幸伸、小井田奈美、原田浩之
- Organizer
  日本口腔外科学会関東支部学術集会
- Data Source
  KAKENHI-PROJECT-19K18959
[Presentation] Quantitation of multiple immune cell subsets in tongue squamous cell carcinoma by multiplexed immunofluorescence.2021
- Author(s)
  Daroonpan Pissacha, Naoto Nishii, Miyuki Azuma
- Organizer
  第25 回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] PD-1阻害抗体：Nivolumab投与効果を予測する新規評価系樹立の取り組み2021
- Author(s)
  西井直人、髙川祐樹、髙橋幸伸、小井田奈美、原田浩之
- Organizer
  口腔外科学会　関東支部学術集会
- Data Source
  KAKENHI-PROJECT-19K18959
[Presentation] マルチプレックス免疫組織染色による舌扁平上皮癌の免疫プロファイリング解析2021
- Author(s)
  Daroonpan Pissacha、加島　義久、濱垣　美和子、西井　直人、津島　文彦、原田　浩之、池田　通、東みゆき
- Organizer
  第75 回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] Immune profiling analyses of tongue squamous cell carcinoma by multiplex immunofluorescence.2021
- Author(s)
  Daroonpan Pissacha, Naoto Nishii, Yoshihisa Kashima, Fumihiko Tsushima, Hiroyuki Harada, Tohru Ikeda, Miyuki Azuma
- Organizer
  第66 回日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-21H03138
[Presentation] 同時性口腔多発癌における全エクソーム解析によるClonality分析2020
- Author(s)
  西井直人、髙川祐樹、髙橋幸伸、小井田奈美、原田浩之
- Organizer
  日本口腔外科学会総会
- Data Source
  KAKENHI-PROJECT-19K18959
[Presentation] 上顎に転移した腎細胞癌の1例2019
- Author(s)
  西井直人，島本裕彰，横川美咲，佐藤百合子，佐藤　潔, 大畑　八重，栢森　高，池田　通，原田浩之
- Organizer
  頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K18959

1. 津島文彦 (90456210)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. Azuma Miyuki (90255654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. 池田通 (00211029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. 相田潤 (80463777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 永井重徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NISHII NAOTO 西井 直人

Nishii Naoto 西井 直人

Research Projects

Research Products

Co-Researchers

口腔扁平苔癬の病勢指標となるバイオマーカーの探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

口腔癌の抗PD-1抗体治療効果を予測する、免疫応答を多角的に捉えた新規評価系樹立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Proposal of multidisciplinary approach based on immune profiling in oral cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the immunosuppressive mechanism of oral cancer to identify the patients who respond to nivolumabPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Observation of dynamic changes in neutrophil-to-lymphocyte ratio is useful for evaluating treatment response to nivolumab in PD-L1-negative advanced oral cancer2022

Author(s)

Journal Title

Data Source

[Journal Article] Discrepancy Between Clinical Diagnosis and Whole-exome Sequencing-based Clonality Analysis of Synchronous Multiple Oral Cancers2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Renal cell carcinoma metastasis to the maxillary bone successfully treated with surgery after vascular embolization: a case report2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Personal immune profiles of oral tongue squamous cell carcinoma -Part 1: Analyses of 87 cases of surgical specimens and immune subtype classification2024

Author(s)

Organizer

Data Source

[Presentation] Personal immune profiles of oral tongue squamous cell carcinoma -Part 2: Analyses of the patients treated with PD-1 immune checkpount inhibitors-2024

Author(s)

Organizer

Data Source

[Presentation] 舌扁平上皮癌のパーソナル免疫プロファイル-包括的免疫パラメーター解析と予後予測-2023

Author(s)

Organizer

Data Source

[Presentation] 舌扁平上皮癌における PD-1 免疫チェックポイント阻害剤投与症例の免疫プロ ファイリング解析2023

Author(s)

Organizer

Data Source

[Presentation] 舌扁平上皮癌における PD-1 免疫チェックポイント阻害剤投与症例の免疫プロファイリング解析2023

Author(s)

Organizer

Data Source

[Presentation] 肉眼分類とがん浸潤様式からみた舌扁平上皮癌の免疫プロファイルの多様性2022

Author(s)

Organizer

Data Source

[Presentation] Comprehensive analyses between clinical outcome and immunopathological profiles in tongue SCC2022

Author(s)

Organizer

Data Source

[Presentation] 肉眼分類とがん浸潤様式から見た舌扁平上皮癌の免疫プロファイルの多様性2022

Author(s)

Organizer

Data Source

NISHII NAOTO 西井直人

Nishii Naoto 西井直人

[Presentation] 舌扁平上皮癌における PD-1 免疫チェックポイント阻害剤投与症例の免疫プロファイリング解析2023