Kato Kohji 加藤耕治

Researcher Number	40844056
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 名古屋市立大学, 医薬学総合研究院(医学), 助教 2023: 名古屋市立大学, 医学(系)研究科(研究院), 研究員 2020 – 2022: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2019 – 2022: 名古屋大学, 環境医学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / 0802:Biomedical structure and function and related fields
Keywords	Principal Investigator ３C症候群 / エンドソーム / エンドソームリサイクル / 3C症候群 / Nestin-Cre / Prx1-Cre / 骨形成異常 / レトリーバー複合体 / VPS35L / 脂質異常症 … More / リサイクル / 膜蛋白 / WASH複合体 / エンドソームリサイクル機構 / レトリバー複合体 / 骨形成異常症 / Ritcher-Schinzel症候群 / 先天異常症候群 / リサイクル機能 / 水頭症 / 筋肉 Less

Identification of novel recycling mechanisms in endosomal membrane protein trafficking in the context of disease pathology.Principal Investigator
- Principal Investigator
  
  加藤耕治
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya City University
エンドソームの膜蛋白輸送に着目した3C症候群の病態解明Principal Investigator
- Principal Investigator
  
  加藤耕治
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya City University
エンドソームリサイクル機能障害が引き起こす疾患の全体像の解明Principal Investigator
- Principal Investigator
  
  加藤耕治
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya City University
Identification of molecular mechanism in a novel congenital malformation syndrome caused by retriever dysfunction.Principal Investigator
- Principal Investigator
  
  Kato Kohji
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0802:Biomedical structure and function and related fields
- Research Institution
  Nagoya City University
  Nagoya University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Gain-of-function MYCN causes a megalencephaly-polydactyly syndrome manifesting mirror phenotypes of Feingold syndrome2023
- Author(s)
  Nishio Yosuke、Kato Kohji、Tran Mau-Them Frederic、Futagawa Hiroshi、Quelin Chloe、Masuda Saori、Vitobello Antonio、Otsuji Shiomi、Shawki Hossam H.、Oishi Hisashi、Thauvin-Robinet Christel、Takenouchi Toshiki、Kosaki Kenjiro、Takahashi Yoshiyuki、Saitoh Shinji
- Journal Title
  
  Human Genetics and Genomics Advances
  
  Volume: 4 Issue: 4 Pages: 100238-100238
- DOI
  10.1016/j.xhgg.2023.100238
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14945, KAKENHI-PROJECT-23KJ1817, KAKENHI-PROJECT-23K05601, KAKENHI-PROJECT-20H03646
[Journal Article] Generalized Verrucosis on a Background of 3C Syndrome Treated With Subcutaneous IgG Supplementation2023
- Author(s)
  Fukaura Ryo、Terashima-Murase Chiaki、Tanahashi Kana、Sato Yoshitaka、Kawase Masaaki、Kato Kohji、Akiyama Masashi
- Journal Title
  
  JAMA Dermatology
  
  Volume: 159 Issue: 12 Pages: 1397-1397
- DOI
  10.1001/jamadermatol.2023.3801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14945, KAKENHI-PROJECT-23KJ1817
[Journal Article] Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome2023
- Author(s)
  Healy Michael D.、McNally Kerrie E.、Butkovi Rebeka、Chilton Molly、Kato Kohji、Derivery Emmanuel、Collins Brett M.、Cullen Peter J, et al.
- Journal Title
  
  Cell
  
  Volume: 186 Issue: 10 Pages: 2219-2237
- DOI
  10.1016/j.cell.2023.04.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16897, KAKENHI-PROJECT-23K14945, KAKENHI-PROJECT-23KJ1817, KAKENHI-PROJECT-19K23823
[Journal Article] Clinical diversity and molecular mechanism of VPS35L-associated Ritscher-Schinzel syndrome2022
- Author(s)
  Otsuji Shiomi、Nishio Yosuke、Tsujita Maki、Rio Marlene、Huber Celine、Anton-Plagaro Carlos、Mizuno Seiji、Kawano Yoshihiko、Miyatake Satoko、Simon Marleen、van Binsbergen Ellen、van Jaarsveld Richard H、Matsumoto Naomichi、Cormier-Daire Valerie、J.Cullen Peter、Saitoh Shinji、Kato Kohji
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 60 Issue: 4 Pages: 359-367
- DOI
  10.1136/jmg-2022-108602
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08631, KAKENHI-PROJECT-19K23823, KAKENHI-PROJECT-20H03646, KAKENHI-PROJECT-20K16897, KAKENHI-PROJECT-23K14945, KAKENHI-PROJECT-23KJ1817, KAKENHI-PROJECT-23K27520
[Journal Article] A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders2021
- Author(s)
  Kato Kohji、Miya Fuyuki、Oka Yasuyoshi、Mizuno Seiji、Saitoh Shinji
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 66 Issue: 5 Pages: 491-498
- DOI
  10.1038/s10038-020-00868-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21583, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-20H03646, KAKENHI-PROJECT-18H03372, KAKENHI-PROJECT-20K16897, KAKENHI-PROJECT-19K23823
[Journal Article] Phosphorylated proteome analysis of a novel germline ABL1 mutation causing an autosomal dominant syndrome with ventricular septal defect2021
- Author(s)
  Yamamoto Hidenori、Hayano Satoshi、Okuno Yusuke、Onoda Atsuto、Kato Kohji、Nagai Noriko、Fukasawa Yoshie、Saitoh Shinji、Takahashi Yoshiyuki、Kato Taichi
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 326 Pages: 81-87
- DOI
  10.1016/j.ijcard.2020.10.032
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08319, KAKENHI-PROJECT-20K08155, KAKENHI-PROJECT-20K21583, KAKENHI-PROJECT-19K17324, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-19K17357, KAKENHI-PROJECT-20K16897, KAKENHI-PROJECT-19K23823
[Journal Article] Biallelic VPS35L pathogenic variants cause 3C/Ritscher-Schinzel-like syndrome through dysfunction of retriever complex.2020
- Author(s)
  Kato K, Okuno Y, Vasilev FF, Otomo T, Oishi H, Muramatsu H, Kawano Y, Oka Y, Nakazawa Y, Ogi T, Takahashi Y, Saitoh S.
- Journal Title
  
  Journal of Medical genetics
  
  Volume: 57 Issue: 4 Pages: 245-253
- DOI
  10.1136/jmedgenet-2019-106213
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-17H01877, KAKENHI-PROJECT-17H05088, KAKENHI-PROJECT-17K10075, KAKENHI-PROJECT-20K21583, KAKENHI-PROJECT-19K23823, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-18K19585, KAKENHI-PROJECT-20H00629
[Journal Article] Expanding the phenotype of biallelic loss‐of‐function variants in the <scp> <i>NSUN2</i> </scp> gene: Description of four individuals with juvenile cataract, chronic nephritis, or brain anomaly as novel complications2020
- Author(s)
  Kato Kohji、Mizuno Seiji、Morton Jenny、Toyama Miho、Hara Yuichiro、Wasmer Evangeline、Lehmann Alan、Ogi Tomoo
- Journal Title
  
  American Journal of Medical Genetics Part A
  
  Volume: 185 Issue: 1 Pages: 282-285
- DOI
  10.1002/ajmg.a.61927
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03372, KAKENHI-PROJECT-20K16897, KAKENHI-PROJECT-19K23823, KAKENHI-PROJECT-20H00629
[Presentation] MYCN gain-of-function variants cause a novel megalencephaly syndrome, resulting from an excess proliferative function of mutant protein.2021
- Author(s)
  Yosuke Nishio, Kohji Kato, Shiomi Otsuji, Tran Mau Them Fred4,Shinji Saitoh
- Organizer
  The American Society of Human Genetics Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16897
[Presentation] Biallelic VPS35L pathogenic variants cause Ritscher-Schinzel-like syndrome: Description of clinical diversity and molecular mechanism.2021
- Author(s)
  Shiomi Otsuji, Kohji Kato, Celine Huber,Seiji Mizuno, Mariene Rio, Satoko Miyatake, Naomichi Matsumoto, Valerie Cormier Daire, Shinji Saitoh
- Organizer
  The American Society of Human Genetics Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23823
[Presentation] Biallelic VPS35L pathogenic variants cause Ritscher-Schinzel-like syndrome: Description of clinical diversity and molecular mechanism.2021
- Author(s)
  Shiomi Otsuji, Kohji Kato, Celine Huber,Seiji Mizuno, Mariene Rio, Satoko Miyatake, Naomichi Matsumoto, Valerie Cormier Daire, Shinji Saitoh
- Organizer
  The American Society of Human Genetics Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16897
[Presentation] Uncovering the underlying molecular mechanism in patients with Retriever dysfunction2021
- Author(s)
  Kohji Kato, Peter J Cullen
- Organizer
  UK membrane trafficking
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23823
[Presentation] Uncovering the underlying molecular mechanism in patients with Retriever dysfunction2021
- Author(s)
  Kohji Kato, Peter J Cullen
- Organizer
  United Kingdom Membrane Trafficking
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16897
[Presentation] A novel case with biallelic VPS35L variants confirms VPS35L as a causative gene of 3C/Ritscher-Schinzel-like syndrome.2020
- Author(s)
  Shiomi Otsuji, Kohji Kato, Seiji Mizuno, Satoko Miyatake, Naomichi Matsumoto, Shinji Saitoh
- Organizer
  第65回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-19K23823
[Presentation] VPS35Lの両アレルにおける機能喪失型バリアントは 3C/Ritscher-Schinzel 症候群に類似の先天異常症候群の原因となる2019
- Author(s)
  加藤耕治, 岡泰由, 村松秀城, Vasilev F, 大友孝信, 大石久史, 河野好彦, 中沢由華, 荻朋男, 高橋義行, 齋藤伸治.
- Organizer
  日本人類遺伝学会第64回大会
- Data Source
  KAKENHI-PROJECT-19K23823
[Presentation] Biallelic VPS35L pathogenic variants cause 3C/Ritscher-Schinzel-like syndrome through dysfunction of retriever complex2019
- Author(s)
  Kato K, Oka Y, Muramatsu H, Vasilev F, Otomo T, Oishi H, Kawano Y, Nakazawa Y, Ogi T, Takahashi Y, Saitoh S.
- Organizer
  ASHG 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23823

1. OGI Tomoo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. KATO Taichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 斉藤伸治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 辻田麻紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 深澤佳絵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kato Kohji 加藤 耕治

Research Projects

Research Products

Co-Researchers

Identification of novel recycling mechanisms in endosomal membrane protein trafficking in the context of disease pathology.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エンドソームの膜蛋白輸送に着目した3C症候群の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エンドソームリサイクル機能障害が引き起こす疾患の全体像の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of molecular mechanism in a novel congenital malformation syndrome caused by retriever dysfunction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Gain-of-function MYCN causes a megalencephaly-polydactyly syndrome manifesting mirror phenotypes of Feingold syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generalized Verrucosis on a Background of 3C Syndrome Treated With Subcutaneous IgG Supplementation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical diversity and molecular mechanism of VPS35L-associated Ritscher-Schinzel syndrome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphorylated proteome analysis of a novel germline ABL1 mutation causing an autosomal dominant syndrome with ventricular septal defect2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biallelic VPS35L pathogenic variants cause 3C/Ritscher-Schinzel-like syndrome through dysfunction of retriever complex.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expanding the phenotype of biallelic loss‐of‐function variants in the <scp> <i>NSUN2</i> </scp> gene: Description of four individuals with juvenile cataract, chronic nephritis, or brain anomaly as novel complications2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] MYCN gain-of-function variants cause a novel megalencephaly syndrome, resulting from an excess proliferative function of mutant protein.2021

Author(s)

Organizer

Data Source

[Presentation] Biallelic VPS35L pathogenic variants cause Ritscher-Schinzel-like syndrome: Description of clinical diversity and molecular mechanism.2021

Author(s)

Organizer

Data Source

[Presentation] Biallelic VPS35L pathogenic variants cause Ritscher-Schinzel-like syndrome: Description of clinical diversity and molecular mechanism.2021

Author(s)

Organizer

Data Source

Kato Kohji 加藤耕治

[Presentation] VPS35Lの両アレルにおける機能喪失型バリアントは 3C/Ritscher-Schinzel 症候群に類似の先天異常症候群の原因となる2019