KAWANA HIROKI 川名裕己

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Kawana Hiroki 川名裕己

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Researcher Number	40846672
Other IDs	https://orcid.org/0000-0002-9695-5973
Affiliation (Current)	2024: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 2020 – 2022: 東京大学, 大学院薬学系研究科(薬学部), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator リン脂質 / 網膜変性 / 脂質代謝 / 細胞突起 / 細胞外小胞 / クリックケミストリー / 質量分析 / 脂質代謝酵素 / リゾリン脂質 / 脂肪酸アナログ … More / PAQR / クリック反応 / ベージュ化 / 寒冷刺激 / 褐色脂肪組織 / ホスホリパーゼA / 脂肪酸誘導体 / リゾリン脂質アシルトランスフェラーゼ / ミトコンドリア / 神経細胞形態 / 精子形成 / ゼブラフィッシュ / オレイン酸 / ステアリン酸 / リン脂質sn-1位 / 脂肪酸リモデリング / リゾリン脂質アシル基転移酵素 Less

細胞突起に由来する細胞外小胞形成における脂質代謝が果たす役割の解明Principal Investigator
- Principal Investigator
  
  川名裕己
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Nara Institute of Science and Technology
Analysis of phospholipid sn-1 fatty acid-determining factor and establishment of target molecule identification techniquePrincipal Investigator
- Principal Investigator
  
  Kawana Hiroki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Nara Institute of Science and Technology
  The University of Tokyo
Analysis of novel phospholipid sn-1 position lysophospholipid acyltransferasesPrincipal Investigator
- Principal Investigator
  
  Kawana Hiroki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Structural basis for lysophosphatidylserine recognition by GPR342024
- Author(s)
  Izume Tamaki、Kawahara Ryo、Uwamizu Akiharu、Chen Luying、Yaginuma Shun、Omi Jumpei、Kawana Hiroki、Hou Fengjue、Sano Fumiya K.、Tanaka Tatsuki、Kobayashi Kazuhiro、Okamoto Hiroyuki H.、Kise Yoshiaki、Ohwada Tomohiko、Aoki Junken、Shihoya Wataru、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 902-902
- DOI
  10.1038/s41467-024-45046-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19263, KAKENHI-PROJECT-22K19371, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-22KJ0577, KAKENHI-PROJECT-22KJ0604, KAKENHI-PROJECT-21H05037, KAKENHI-PROJECT-23K23819, KAKENHI-PLANNED-19H05777
[Journal Article] LPGAT1/LPLAT7 regulates acyl chain profiles at the sn-1 position of phospholipids in murine skeletal muscles2023
- Author(s)
  Sato Tomoki、Umebayashi Shuhei、Senoo Nanami、Akahori Takumi、Ichida Hiyori、Miyoshi Noriyuki、Yoshida Takuya、Sugiura Yuki、Goto-Inoue Naoko、Kawana Hiroki、Shindou Hideo、Baba Takashi、Maemoto Yuki、Kamei Yasutomi、Shimizu Takao、Aoki Junken、Miura Shinji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 7 Pages: 104848-104848
- DOI
  10.1016/j.jbc.2023.104848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18179, KAKENHI-PROJECT-23K18436, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-22K17831, KAKENHI-PROJECT-21H03362, KAKENHI-PROJECT-23K24796
[Journal Article] Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels2023
- Author(s)
  Tatsumi Manae、Kishi Takayuki、Ishida Satoru、Kawana Hiroki、Uwamizu Akiharu、Ono Yuki、Kawakami Kouki、Aoki Junken、Inoue Asuka
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 1 Pages: e0280448-e0280448
- DOI
  10.1371/journal.pone.0280448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15273, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-20J20669, KAKENHI-PROJECT-22KJ0224
[Journal Article] Isosteric Replacement of Ester Linkage of Lysophospholipids with Heteroaromatic Rings Retains Potency and Subtype Selectivity2023
- Author(s)
  Ikubo Masaya、Uwamizu Akiharu、Chen Luying、Nakamura Sho、Sayama Misa、Kawana Hiroki、Otani Yuko、Kano Kuniyuki、Inoue Asuka、Aoki Junken、Ohwada Tomohiko
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 71 Issue: 7 Pages: 584-615
- DOI
  10.1248/cpb.c23-00250
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2023-07-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06022, KAKENHI-PROJECT-22K15273
[Journal Article] Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles2022
- Author(s)
  Yaginuma Shun、Kawana Hiroki、Aoki Junken
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 8 Pages: 2487-2487
- DOI
  10.3390/molecules27082487
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20K21379, KAKENHI-PROJECT-19H03366, KAKENHI-PROJECT-22H00438
[Journal Article] Identification and characterization of LPLAT7 as an sn-1-specific lysophospholipid acyltransferase2022
- Author(s)
  Kawana Hiroki、Ozawa Masaya、Shibata Takeaki、Onishi Hirofumi、Sato Yukitaka、Kano Kuniyuki、Shindou Hideo、Shimizu Takao、Kono Nozomu、Aoki Junken
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 63 Issue: 10 Pages: 100271-100271
- DOI
  10.1016/j.jlr.2022.100271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20K21379, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-20H03380
[Journal Article] Phenotypic evaluation of constitutive GPCR/G-protein signaling in zebrafish embryos and larvae2022
- Author(s)
  Shibata Takeaki、Kawakami Kouki、Kawana Hiroki、Aoki Junken、Inoue Asuka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 602 Pages: 70-76
- DOI
  10.1016/j.bbrc.2022.02.098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15273, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-21H04791
[Journal Article] Abnormal male reproduction and embryonic development induced by downregulation of a phospholipid fatty acid-introducing enzyme Lpgat1 in zebrafish2022
- Author(s)
  Shibata T, Kawana H, Nishino Y, Ito Y, Sato H, Onishi H, Kano K, Inoue A, Taketomi Y, Murakami M, Kofuji S, Nishina H, Miyazawa A, Kono N, Aoki J.
- Journal Title
  
  Scientific reports
  
  Volume: 12 Issue: 1 Pages: 7312-7312
- DOI
  10.1038/s41598-022-11002-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15984, KAKENHI-PROJECT-21K06544, KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20H03381, KAKENHI-PROJECT-20K21379, KAKENHI-PROJECT-20H05691, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-20H03380
[Journal Article] TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis2022
- Author(s)
  Petkevicius Kasparas、Palmgren Henrik、他19人、Kono Nozomu、Aoki Junken、Hess Sonja、Sienski Grzegorz、Pilon Marc、Bohlooly-Y Mohammad、Maresca Marcello、Peng Xiao-Rong
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 6020-6020
- DOI
  10.1038/s41467-022-33735-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20K21379, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-20H03380
[Presentation] アシル基転移酵素LPGAT1/LPLAT7の過剰発現が筋性状・筋機能に及ぼす影響2023
- Author(s)
  曾我茜 , 市田日和 , 三好規之 , 三好規之 , 川名裕己 , 青木淳賢 , 佐藤友紀 , 三浦進司
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K15273
[Presentation] アシル基転移酵素LPLAT7による腸管上皮細胞のPCアシル基リモデリングと糖質の消化・吸収への影響2023
- Author(s)
  小野利佳子 , 佐藤友紀 , 村上紗希 , 三好規之 , 川名裕己 , 青木淳賢
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K15273
[Presentation] LPGAT1/LPLAT7による骨格筋中リン脂質のアシル基リモデリング機構の解明とLPGAT1/LPLAT7欠損が骨格筋機能に及ぼす影響2023
- Author(s)
  滝田紗恵梅林修平佐藤友紀妹尾奈波赤堀拓三好規之杉浦悠毅井上菜穂子川名裕己幡野敦松本雅記進藤英雄亀井康富清水孝雄青木淳賢三浦進司
- Organizer
  脂質生化学会
- Data Source
  KAKENHI-PROJECT-22K15273
[Presentation] THP-1細胞分化に伴うリン脂質脂肪酸鎖リモデリングを担う分子の探索2023
- Author(s)
  岩田紘歩 , 坂本新悟 , 川名裕己 , 河野望 , 青木淳賢
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K15273
[Presentation] 腸管上皮におけるアシル基転移酵素LPGAT1/LPLAT7を介したリン脂質クオリティの制御と栄養素吸収機能への影響2023
- Author(s)
  小野利佳子 , 佐藤友紀 , 村上紗希 , 三好規之 , 川名裕己 , 青木淳賢 , 三浦進司
- Organizer
  脂質生化学会
- Data Source
  KAKENHI-PROJECT-22K15273
[Presentation] PAQRファミリー分子は新規リン脂質代謝酵素群である2022
- Author(s)
  川名裕己、大西浩文、八木優太朗、可野邦行、河野望、田辺弘明、岩部-岡田美紀、岩部真人、山内敏正、門脇孝、横山茂之、青木淳賢
- Organizer
  第95回日本生化学会
- Data Source
  KAKENHI-PROJECT-22K15273
[Presentation] LPLAT7/LPGAT1によるER形態制御機構の解析2022
- Author(s)
  川名裕己、小澤雅也、河野望、青木淳賢
- Organizer
  第64日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-22K15273
[Presentation] ステアリン酸含有リン脂質の培養細胞レベルでの機能解析2021
- Author(s)
  小澤雅也、川名裕己、可野邦行、河野望、青木淳賢
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-20K15984
[Presentation] LPLAT7/LPGAT1欠損体における網膜変性機構の解析2021
- Author(s)
  川名裕己、柴田剛明、岩間大河、相良洋、佐藤悠喜飛、可野邦行、河野望、青木淳賢
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-20K15984
[Presentation] ゼブラフィッシュはリン脂質分子種の多様性の意義解明に有用なモデル生物である2021
- Author(s)
  柴田剛明、川名裕己、大西浩文、河野望、青木淳賢
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-20K15984
[Presentation] ゼブラフィッシュを用いたLPLAT10/LPCAT4/LPEAT2の生理的意義の解析2021
- Author(s)
  大西浩文、柴田剛明、川名裕己、河野望、青木淳賢
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-20K15984
[Presentation] リン脂質sn -1位代謝機構による細胞機能の制御2020
- Author(s)
  川名裕己、小澤雅也、柴田剛明、佐藤悠喜飛、可野邦行、青木淳賢
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K15984

1. KONO Nozomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 青木淳賢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 木瀬孔明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWANA HIROKI 川名 裕己

Kawana Hiroki 川名 裕己

Research Projects

Research Products

Co-Researchers

細胞突起に由来する細胞外小胞形成における脂質代謝が果たす役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of phospholipid sn-1 fatty acid-determining factor and establishment of target molecule identification techniquePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of novel phospholipid sn-1 position lysophospholipid acyltransferasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Structural basis for lysophosphatidylserine recognition by GPR342024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LPGAT1/LPLAT7 regulates acyl chain profiles at the sn-1 position of phospholipids in murine skeletal muscles2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isosteric Replacement of Ester Linkage of Lysophospholipids with Heteroaromatic Rings Retains Potency and Subtype Selectivity2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification and characterization of LPLAT7 as an sn-1-specific lysophospholipid acyltransferase2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phenotypic evaluation of constitutive GPCR/G-protein signaling in zebrafish embryos and larvae2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Abnormal male reproduction and embryonic development induced by downregulation of a phospholipid fatty acid-introducing enzyme Lpgat1 in zebrafish2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] アシル基転移酵素LPGAT1/LPLAT7の過剰発現が筋性状・筋機能に及ぼす影響2023

Author(s)

Organizer

Data Source

[Presentation] アシル基転移酵素LPLAT7による腸管上皮細胞のPCアシル基リモデリングと糖質の消化・吸収への影響2023

Author(s)

Organizer

Data Source

[Presentation] LPGAT1/LPLAT7による骨格筋中リン脂質のアシル基リモデリング機構の解明とLPGAT1/LPLAT7欠損が骨格筋機能に及ぼす影響2023

KAWANA HIROKI 川名裕己

Kawana Hiroki 川名裕己