Saotome Tomonori 早乙女友規

Researcher Number	40867610
Other IDs
Affiliation (Current)	2025: 小山工業高等専門学校, 物質工学科, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 長岡技術科学大学, 工学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related
Keywords	Principal Investigator 蛋白質の熱凝集 / 高温でのRO形成 / 一残基置換 / DSC測定 / 蛋白質凝集 / アミロイド線維 / 蛋白質工学

The development of molecular design to inhibit the amyloid fibrillation by inhibiting the reversible oligomerization at high temperature with a single residue mutationPrincipal Investigator
- Principal Investigator
  
  Saotome Tomonori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Nagaoka University of Technology

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] The Reversible Oligomerization (RO) of Small Globular Proteins at High-Temperature and the Inhibition of Their Amyloidogenesis2023
- Author(s)
  早乙女　友規
- Journal Title
  
  Netsu Sokutei
  
  Volume: 50 Issue: 3 Pages: 103-109
- DOI
  10.11311/jscta.50.3_103
- ISSN
  0386-2615, 1884-1899
- Year and Date
  2023-07-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15049
[Journal Article] Blocking PSD95‐PDZ3's amyloidogenesis through point mutations that inhibit high‐temperature reversible oligomerization (RO)2022
- Author(s)
  Saotome Tomonori、Onchaiya Sawaros、Brindha Subbaian、Mezaki Taichi、Unzai Satoru、Noguchi Keiichi、Martinez Jose C.、Kidokoro Shun‐ichi、Kuroda Yutaka
- Journal Title
  
  The FEBS Journal
  
  Volume: 2021 Issue: 11 Pages: 1-12
- DOI
  10.1111/febs.16339
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05288, KAKENHI-PROJECT-21K15049, KAKENHI-PROJECT-18H02385
[Journal Article] Reverse Engineering Analysis of the High-Temperature Reversible Oligomerization and Amyloidogenicity of PSD95-PDZ32022
- Author(s)
  Onchaiya Sawaros、Saotome Tomonori、Mizutani Kenji、Martinez Jose C.、Tame Jeremy R. H.、Kidokoro Shun-ichi、Kuroda Yutaka
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 9 Pages: 2813-2813
- DOI
  10.3390/molecules27092813
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05288, KAKENHI-PROJECT-21K15049
[Presentation] Reversible Oligomerization (RO) at high temperature: a trigger of complicated thermal transition of small globular proteins2023
- Author(s)
  Tomonori Saotome, Sawaros Onchaiya, Brindha Subbaian, Jose Martinez, Yutaka Kuroda, Shun-ichi Kidokoro
- Organizer
  第12回日本生物物理学会関東支部会
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] Physicochemical characterization of irreversible oligomers considered precursors of thermal aggregation of hen egg white lysozyme2023
- Author(s)
  Tomonori Saotome, Shun-ichi Kidokoro
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] The characterization of reversible oligomer (RO) at high temperature and the assessment of thermal aggregation of hen egg white lysozyme2023
- Author(s)
  Tomonori Saotome, Shun-ichi Kidokoro
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] The reversible oligomerization (RO) of small globular proteins at high-temperature and the artificial suppression of their amyloidogenesis2023
- Author(s)
  Tomonori Saotome, Sawaros Onchaiya, Brindha Subbaian, Jose Martinez, Yutaka Kuroda, Shun-ichi Kidokoro
- Organizer
  26th International Conference on Chemical Thermodynamics (ICCT-2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] PSD95-PDZ3の高温での可逆的なオリゴマー（RO）形成およびアミロイド線維の一残基置換による阻害2022
- Author(s)
  早乙女友規
- Organizer
  第62回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] PSD95-PDZ3の高温での可逆的なオリゴマー形成における速度論的効果の定量的な評価2022
- Author(s)
  Tomonori Saotome, Onchaiya Sawaros, Jose C Martinez, Yutaka Kuroda, Shun-ichi Kidokoro
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] PSD95-PDZ3の高温での可逆的なオリゴマー（RO）の一残基置換による阻害を利用したアミロイド線維形成の抑制2021
- Author(s)
  早乙女友規, Onchaiya Sawaros, 城所俊一, 黒田裕
- Organizer
  第 57 回熱測定討論会
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] PSD95-PDZ3の一残基置換による高温での可逆的なオリゴマー（RO）形成の阻害およびアミロイド線維の抑制2021
- Author(s)
  早乙女友規, Onchaiya Sawaros, 目崎太一, Martinez Jose, 城所俊一, 黒田裕
- Organizer
  第59回日本生物物理学会年会 2021年11月27日
- Data Source
  KAKENHI-PROJECT-21K15049
[Presentation] Reverse engineering of high-temperature reversible oligomers and amyloids in PDZ32021
- Author(s)
  Sawaros Onchaiya, Tomonori Saotome, Shun-ichi Kidokoro, Jose C. Martinez, Yutaka Kuroda
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K15049

1. 城戸俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Saotome Tomonori 早乙女 友規

Research Projects

Research Products

Co-Researchers

The development of molecular design to inhibit the amyloid fibrillation by inhibiting the reversible oligomerization at high temperature with a single residue mutationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The Reversible Oligomerization (RO) of Small Globular Proteins at High-Temperature and the Inhibition of Their Amyloidogenesis2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Blocking PSD95‐PDZ3's amyloidogenesis through point mutations that inhibit high‐temperature reversible oligomerization (RO)2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reverse Engineering Analysis of the High-Temperature Reversible Oligomerization and Amyloidogenicity of PSD95-PDZ32022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Reversible Oligomerization (RO) at high temperature: a trigger of complicated thermal transition of small globular proteins2023

Author(s)

Organizer

Data Source

[Presentation] Physicochemical characterization of irreversible oligomers considered precursors of thermal aggregation of hen egg white lysozyme2023

Author(s)

Organizer

Data Source

[Presentation] The characterization of reversible oligomer (RO) at high temperature and the assessment of thermal aggregation of hen egg white lysozyme2023

Author(s)

Organizer

Data Source

[Presentation] The reversible oligomerization (RO) of small globular proteins at high-temperature and the artificial suppression of their amyloidogenesis2023

Author(s)

Organizer

Data Source

[Presentation] PSD95-PDZ3の高温での可逆的なオリゴマー（RO）形成およびアミロイド線維の一残基置換による阻害2022

Author(s)

Organizer

Data Source

[Presentation] PSD95-PDZ3の高温での可逆的なオリゴマー形成における速度論的効果の定量的な評価2022

Author(s)

Organizer

Data Source

[Presentation] PSD95-PDZ3の高温での可逆的なオリゴマー（RO） の一残基置換による阻害を利用したアミロイド線維形成 の抑制2021

Author(s)

Organizer

Data Source

[Presentation] PSD95-PDZ3の一残基置換による高温での可逆的なオリゴマー（RO）形成の阻害およびアミロイド線維の抑制2021

Author(s)

Organizer

Data Source

[Presentation] Reverse engineering of high-temperature reversible oligomers and amyloids in PDZ32021

Author(s)

Organizer

Data Source

Saotome Tomonori 早乙女友規

[Presentation] PSD95-PDZ3の高温での可逆的なオリゴマー（RO）の一残基置換による阻害を利用したアミロイド線維形成の抑制2021