Anzai Itsuki 安齋樹

Researcher Number	40868824
Other IDs
Affiliation (Current)	2025: 大阪大学, 微生物病研究所, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 大阪大学, 微生物病研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related Except Principal Investigator Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator RNAウイルス / 宿主因子 / 抗ウイルス薬 / オートファジー / 病原性発現機構 / RNA複製複合体 / 細胞応答 / 複製機構 / SARS-CoV-2 / ウイルス‐宿主相互作用 … More Except Principal Investigator … More 表面抗原 / 患者抗体 / マラリア / 感染赤血球表面抗原 / 抗体 / マラリア原虫 Less

A mechanism of RNA virus replication regulated by autophagy machineryPrincipal Investigator
- Principal Investigator
  
  安齋樹
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Osaka University
A molecular basis of virus pathogenicity focusing on RNA replicationPrincipal Investigator
- Principal Investigator
  
  Anzai Itsuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Osaka University
Investigation of receptor-inserted antibody in malaria patients
- Principal Investigator
  
  IWANAGA SHIROH
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Characterization of a neutralizing antibody that recognizes a loop region adjacent to the receptor-binding interface of the SARS-CoV-2 spike receptor-binding domain.2024
- Author(s)
  Anzai I, Fujita J, Ono C, Kosaka Y, Miyamoto Y, Shichinohe S, Takada K, Torii S, Taguwa S, Suzuki K, Makino F, Kajita T, Inoue T, Namba K, Watanabe T, Matsuura Y
- Journal Title
  
  Microbiol Spectr.
  
  Volume: 12 Issue: 4
- DOI
  10.1128/spectrum.03655-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07039, KAKENHI-PROJECT-21K15042, KAKENHI-PROJECT-22K15469, KAKENHI-PROJECT-23K23821
[Journal Article] Epoxidized graphene grid for highly efficient high-resolution cryoEM structural analysis2023
- Author(s)
  Fujita Junso、Makino Fumiaki、Asahara Haruyasu、Moriguchi Maiko、Kumano Shota、Anzai Itsuki、Kishikawa Jun-ichi、Matsuura Yoshiharu、Kato Takayuki、Namba Keiichi、Inoue Tsuyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 2279-2279
- DOI
  10.1038/s41598-023-29396-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15042, KAKENHI-PROJECT-20K22630, KAKENHI-PROJECT-23K23821
[Journal Article] Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses2022
- Author(s)
  Tamura Tomokazu、Torii Shiho、Kajiwara Kentaro、Anzai Itsuki、Fujioka Yoichiro、Noda Kisho、Taguwa Shuhei、Morioka Yuhei、Suzuki Rigel、Fauzyah Yuzy、Ono Chikako、Ohba Yusuke、Okada Masato、Fukuhara Takasuke、Matsuura Yoshiharu
- Journal Title
  
  PLOS Pathogens
  
  Volume: 18 Issue: 6 Pages: e1010593-e1010593
- DOI
  10.1371/journal.ppat.1010593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07151, KAKENHI-PROJECT-21K15042, KAKENHI-PLANNED-20H05872, KAKENHI-PROJECT-21H02736, KAKENHI-PROJECT-19K07639, KAKENHI-PROJECT-21K19347, KAKENHI-PROJECT-21K20760, KAKENHI-PROJECT-23K24138, KAKENHI-PUBLICLY-21H00413
[Journal Article] Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant2022
- Author(s)
  Yamaguchi Keishi、Anzai Itsuki、Maeda Ryota、Moriguchi Maiko、Watanabe Tokiko、Imura Akihiro、Takaori-Kondo Akifumi、Inoue Tsuyoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 2 Pages: 115-127
- DOI
  10.1093/jb/mvac096
- Data Source
  KAKENHI-PROJECT-21K15042
[Journal Article] Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike protein2022
- Author(s)
  Otsubo Ryota、Minamitani Takeharu、Kobiyama Kouji、Fujita Junso、Ito Toshihiro、Ueno Shiori、Anzai Itsuki、Tanino Hiroki、Aoyama Hiroshi、Matsuura Yoshiharu、Namba Keiichi、Imadome Ken-Ichi、Ishii Ken J.、Tsumoto Kouhei、Kamitani Wataru、Yasui Teruhito
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20120-20120
- DOI
  10.1038/s41598-022-24730-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15042, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K22630, KAKENHI-PROJECT-23K23821
[Journal Article] Nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants2022
- Author(s)
  Maeda Ryota、Fujita Junso、Konishi Yoshinobu、Kazuma Yasuhiro、Yamazaki Hiroyuki、Anzai Itsuki、Yamaguchi Keishi、Kasai Kazuki、Nagata Kayoko、Yamaoka Yutaro、Miyakawa Kei、Ryo Akihide、Shirakawa Kotaro、Makino Fumiaki、Matsuura Yoshiharu、Inoue Tsuyoshi、Imura Akihiro、Namba Keiichi、Takaori-Kondo Akifumi
- Journal Title
  
  Communications biology
  
  Volume: 5 Pages: 669-669
- DOI
  10.1101/2021.10.25.465714
- Data Source
  KAKENHI-PROJECT-21K15042
[Journal Article] Establishment and clinical application of SARS-CoV-2 catch column2022
- Author(s)
  Isaka Yoshitaka、Yoshiya Taku、Ono Chikako、Uchiyama Akinori、Hirata Haruhiko、Hamaguchi Shigeto、Kutsuna Satoshi、Takabatake Yoshitsugu、Saita Ryotaro、Yamada Tomomi、Takahashi Atsushi、Yamato Masaya、Nohara Yukie、Tsuda Shugo、Anzai Itsuki、Kimura Tomonori、Takeda Yoshito、Tomono Kazunori、Matsuura Yoshiharu
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 27 Issue: 3 Pages: 279-287
- DOI
  10.1007/s10157-022-02296-9
- Data Source
  KAKENHI-PROJECT-21K15042
[Journal Article] Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction2021
- Author(s)
  Torii Shiho、Ono Chikako、Suzuki Rigel、Morioka Yuhei、Anzai Itsuki、Fauzyah Yuzy、Maeda Yusuke、Kamitani Wataru、Fukuhara Takasuke、Matsuura Yoshiharu
- Journal Title
  
  Cell Reports
  
  Volume: 35 Issue: 3 Pages: 109014-109014
- DOI
  10.1016/j.celrep.2021.109014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15042
[Journal Article] Synthesis of low-molecular weight fucoidan derivatives and their binding abilities to SARS-CoV-2 spike proteins2021
- Author(s)
  Koike Tatsuki, Sugimoto Aoi, Kosono Shuhei, Komaba Sumika, Kanno Yuko, Kitamura Takashi, Anzai Itsuki, Watanabe Tokiko, Takahashi Daisuke, Toshima Kazunobu
- Journal Title
  
  RSC Medicinal Chemistry
  
  Volume: 12 Issue: 12 Pages: 2016-2021
- DOI
  10.1039/d1md00264c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21289, KAKENHI-PROJECT-19H02724, KAKENHI-PROJECT-21K15042
[Journal Article] Ponesimod suppresses hepatitis B virus infection by inhibiting endosome maturation2021
- Author(s)
  Fauzyah Yuzy、Ono Chikako、Torii Shiho、Anzai Itsuki、Suzuki Rigel、Izumi Takuma、Morioka Yuhei、Maeda Yusuke、Okamoto Toru、Fukuhara Takasuke、Matsuura Yoshiharu
- Journal Title
  
  Antiviral Research
  
  Volume: 186 Pages: 104999-104999
- DOI
  10.1016/j.antiviral.2020.104999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-20K22951, KAKENHI-PROJECT-21K15042
[Presentation] SARS-CoV-2増殖を制御する宿主因子の同定と機能解析2023
- Author(s)
  安齋樹、足達俊吾、笠原勇矢、小比賀聡、河岡義裕、渡辺登喜子
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K15042
[Presentation] SARS-CoV-2に対する抗ウイルス活性を有する海洋天然物の探索と作用機序解明2023
- Author(s)
  安齋樹、岩崎有紘、小野慎子、鳥居志保、松浦善治、末永聖武、渡辺登喜子
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K15042
[Presentation] SARS-CoV-2粒子に取り込まれる宿主因子の同定と機能解析2023
- Author(s)
  安齋樹、足達俊吾、河岡義裕、渡辺登喜子
- Organizer
  第70回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K15042
[Presentation] SARS-CoV-2の増殖に関わる宿主因子の同定と機能解析2022
- Author(s)
  安齋樹、足達俊吾、河岡義裕、渡辺登喜子
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15042
[Presentation] SARS-CoV-2抗体医薬開発に資する中和抗体の作用機序の分子基盤2022
- Author(s)
  安齋樹、藤田純三、小野慎子、小坂洋一郎、宮本由紀、七戸新太郎、高田光輔、梶田忠宏、井上豪、難波啓一、渡辺登喜子、松浦善治
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K15042
[Presentation] SARS-CoV-2に対する中和抗体の作製とその作用機序の解明2021
- Author(s)
  安齋樹、小野慎子、小坂洋一郎、宮本由紀、七戸新太郎、高田光輔、梶田忠宏、松浦善治、渡辺登喜子
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15042
[Presentation] 中和抗体の性状解析を通じて理解するSARS-CoV-2の受容体認識の分子メカニズム2021
- Author(s)
  安齋樹、小野慎子、小坂洋一郎、宮本由紀、七戸新太郎、高田光輔、梶田忠宏、松浦善治、渡辺登喜子
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15042

1. IWANAGA SHIROH (20314510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 荒瀬尚 (10261900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 迫口瑛史 (60914174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 猪原史成 (00800773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKAHASHI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. OKAMOTO Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 梶原健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小野慎子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Anzai Itsuki 安齋 樹

Research Projects

Research Products

Co-Researchers

A mechanism of RNA virus replication regulated by autophagy machineryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A molecular basis of virus pathogenicity focusing on RNA replicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of receptor-inserted antibody in malaria patients

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Characterization of a neutralizing antibody that recognizes a loop region adjacent to the receptor-binding interface of the SARS-CoV-2 spike receptor-binding domain.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epoxidized graphene grid for highly efficient high-resolution cryoEM structural analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike protein2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment and clinical application of SARS-CoV-2 catch column2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of low-molecular weight fucoidan derivatives and their binding abilities to SARS-CoV-2 spike proteins2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ponesimod suppresses hepatitis B virus infection by inhibiting endosome maturation2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] SARS-CoV-2増殖を制御する宿主因子の同定と機能解析2023

Author(s)

Organizer

Data Source

[Presentation] SARS-CoV-2に対する抗ウイルス活性を有する海洋天然物の探索と作用機序解明2023

Author(s)

Organizer

Data Source

Anzai Itsuki 安齋樹