HU Xin ＨｕＸｉｎ

… Alternative Names

Hu Xin コキン

Less

Researcher Number	40868965
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 移植免疫研究室, (非)研究員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立成育医療研究センター, 移植免疫研究室, (非)研究員 2023: 国立研究開発法人国立成育医療研究センター, 移植免疫研究室, (非)研究員 2022: 国立研究開発法人国立成育医療研究センター, 移植免疫研究室, 研究員 2021: 国立研究開発法人国立成育医療研究センター, 移植免疫研究室, リサーチアソシエイト
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator TIL / tumor microenvironment / CD8 T cell / CD86 / TILs / TADCs / combined phospholipids / cancer immunotherapy / TME / TADC … More / Combined phospholipids / Macrophage / Tils / TAM / PD-1/PD-L1 / CD11b cells / β-glucan / CD11b+ cells / Tumor microenvironment / PD-L1 … More Except Principal Investigator 免疫寛容 Less

The research of characterization and functional analysis of novel immune cells in tumor immune escape mechanismsPrincipal Investigator
- Principal Investigator
  
  Hu Xin
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Center for Child Health and Development
シングル細胞遺伝子発現と空間的遺伝子発現の多層解析よる移植免疫寛容関連機構の解明
- Principal Investigator
  
  梨井康
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  National Center for Child Health and Development
The research of targeting tumor-associated dendritic cells, a new therapy strategy by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responsesPrincipal Investigator
- Principal Investigator
  
  Hu Xin
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Center for Child Health and Development
The research of targeting tumor-associated macrophages, a new combination therapy strategy by macrophage polarization and immune checkpoint blockadePrincipal Investigator
- Principal Investigator
  
  Hu Xin
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Center for Child Health and Development

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Combined phospholipids adjuvant augments anti-tumor immune responses through activated tumor-associated dendritic cells.2023
- Author(s)
  Shui Y., Hu X., Hirano H., Tsukamoto H., Guo W. Z., Hasumi K., Ijima F., Fujino M., and Li X. K.
- Journal Title
  
  Neoplasia
  
  Volume: 39 Pages: 100893-100893
- DOI
  10.1016/j.neo.2023.100893
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02788, KAKENHI-PROJECT-21K15586
[Journal Article] PD-L1 antibody enhanced β-glucan antitumor effects via blockade of the immune checkpoints in a melanoma model2022
- Author(s)
  Hu Xin、Shui Yifang、Hirano Hiroshi、Kusano Kisato、Guo Wen-Zhi、Fujino Masayuki、Li Xiao-Kang
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 72 Issue: 3 Pages: 719-731
- DOI
  10.1007/s00262-022-03276-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15586
[Journal Article] β-glucan from Aureobasidium pullulans augments the anti-tumor immune responses through activated tumor-associated dendritic cells2021
- Author(s)
  Shui Yifang、Hu Xin、Hirano Hiroshi、Kusano Kisato、Tsukamoto Hirotake、Li Mengquan、Hasumi Kenichiro、Guo Wen-Zhi、Li Xiao-Kang
- Journal Title
  
  International Immunopharmacology
  
  Volume: 101 Pages: 108265-108265
- DOI
  10.1016/j.intimp.2021.108265
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-21K15586
[Presentation] PD-L1 antibody enhanced the β-glucan antitumor effects via blockade the immune checkpoints in melanoma model2022
- Author(s)
  Xin Hu, Hiroshi Hirano, Masayuki Fujino, Xiao-Kang Li
- Organizer
  第81回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15586
[Presentation] Supercooling preservation prolonged cold ischemia time in mouse heart transplantation2022
- Author(s)
  Xin Hu, Weitao Que, Masayuki Fujino, Xiao-Kang Li
- Organizer
  第48回日本臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15586
[Presentation] Liver mononuclear cells-derived NK cells for treatment of hepatocellular carcinoma2022
- Author(s)
  Xin Hu, Masayuki Fujino, Xiao-Kang Li
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15586
[Presentation] Enhancement of antitumor effects of PD-L1 blockade by 5-ALA/SFC via upregulation of exhausted T cells metabolism in mice2021
- Author(s)
  Xin Hu, Hiroshi Hirano, Kenichiro Hasumi, Motowo Nakajima, Xiao-Kang Li.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15586

1. 梨井康 (60321890)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 藤野真之 (50392329)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 中川美和 (90329699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. AWAI Hirotake

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HU Xin Ｈｕ Ｘｉｎ

Hu Xin コ キン

Research Projects

Research Products

Co-Researchers

The research of characterization and functional analysis of novel immune cells in tumor immune escape mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シングル細胞遺伝子発現と空間的遺伝子発現の多層解析よる移植免疫寛容関連機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The research of targeting tumor-associated dendritic cells, a new therapy strategy by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The research of targeting tumor-associated macrophages, a new combination therapy strategy by macrophage polarization and immune checkpoint blockadePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Combined phospholipids adjuvant augments anti-tumor immune responses through activated tumor-associated dendritic cells.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PD-L1 antibody enhanced β-glucan antitumor effects via blockade of the immune checkpoints in a melanoma model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] β-glucan from Aureobasidium pullulans augments the anti-tumor immune responses through activated tumor-associated dendritic cells2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] PD-L1 antibody enhanced the β-glucan antitumor effects via blockade the immune checkpoints in melanoma model2022

Author(s)

Organizer

Data Source

[Presentation] Supercooling preservation prolonged cold ischemia time in mouse heart transplantation2022

Author(s)

Organizer

Data Source

[Presentation] Liver mononuclear cells-derived NK cells for treatment of hepatocellular carcinoma2022

Author(s)

Organizer

Data Source

[Presentation] Enhancement of antitumor effects of PD-L1 blockade by 5-ALA/SFC via upregulation of exhausted T cells metabolism in mice2021

Author(s)

Organizer

Data Source

HU Xin ＨｕＸｉｎ

Hu Xin コキン