Mizutani Shinsuke 水谷信介

Researcher Number	40883088
Other IDs	https://orcid.org/0000-0002-6498-1755
Affiliation (Current)	2024: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2020: 京都府立医科大学, 医学部附属病院, 専攻医
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / 0901:Oncology and related fields Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 骨髄由来抑制系細胞 / インターフェロン刺激遺伝子 / 成熟B細胞性腫瘍 / RSK2 / PDPK1 / 多発性骨髄腫 / B細胞性リンパ腫 / ゲノム編集 / B細胞リンパ腫 / がん抑制遺伝子 / 悪性リンパ腫 / MYC / CRISPR/Cas9 … More Except Principal Investigator … More 創薬 / 多発性骨髄腫 / 悪性リンパ腫 / S6K / AKT / PDPK1 / RSK2 Less

Identification of pathogenesis-promoting interferon-stimulated genes and development of regulatory strategies in mature B-cell tumorsPrincipal Investigator
- Principal Investigator
  
  水谷信介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Generation of RSK2/AKT/S6K tripple inhibitor for mature lymphoid malignancies
- Principal Investigator
  
  黒田純也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the high-grade pathogenesis of universal mature B cell tumor model by using comprehensive gene editingPrincipal Investigator
- Principal Investigator
  
  Mizutani Shinsuke
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation for novel target of aggressive B cell lymphoma by whole genome in vivo CRISPR/Cas9 screeningPrincipal Investigator
- Principal Investigator
  
  Mizutani Shinsuke
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis2023
- Author(s)
  Potts Margaret A.、Mizutani Shinsuke、Garnham Alexandra L.、Li Wai Suen Connie S. N.、Kueh Andrew J.、Tai Lin、Pal Martin、Strasser Andreas、Herold Marco J.
- Journal Title
  
  Cell Death & Differentiation
  
  Volume: - Issue: 6 Pages: 1447-1456
- DOI
  10.1038/s41418-023-01145-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16274
[Journal Article] Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myeloma2023
- Author(s)
  Tsukamoto Taku、Kinoshita Masaki、Yamada Kazuhiro、Ito Hodaka、Yamaguchi Toshikazu、Chinen Yoshiaki、Mizutani Shinsuke、Fujino Takahiro、Kobayashi Tsutomu、Shimura Yuji、Inazawa Johji、Kuroda Junya
- Journal Title
  
  Journal of Human Genetics
  
  Volume: - Issue: 7 Pages: 507-514
- DOI
  10.1038/s10038-023-01136-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16274
[Journal Article] Impact of Treatment with Anti-CD20 Monoclonal Antibody on the Production of Neutralizing Antibody Against Anti?SARS-CoV-2 Vaccination in Mature B-Cell Neoplasms2023
- Author(s)
  Onishi Akio、Matsumura-Kimoto Yayoi、Mizutani Shinsuke、Tsukamoto Taku、Fujino Takahiro、Miyashita Akihiro、Nishiyama Daichi、Shimura Kazuho、Kaneko Hiroto、Kawata Eri、Takahashi Ryoichi、Kobayashi Tsutomu、Uchiyama Hitoji、Uoshima Nobuhiko、Nukui Yoko、Shimura Yuji、Inaba Tohru、Kuroda Junya
- Journal Title
  
  Infection and Drug Resistance
  
  Volume: Volume 16 Pages: 509-519
- DOI
  10.2147/idr.s396271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16274
[Journal Article] The Rationale for the Dual-Targeting Therapy for RSK2 and AKT in Multiple Myeloma.2022
- Author(s)
  Isa R, Horinaka M, Tsukamoto T, Mizuhara K, Fujibayashi Y, Taminishi-Katsuragawa Y, Okamoto H, Yasuda S, Kawaji-Kanayama Y, Matsumura-Kimoto Y, Mizutani S, Shimura Y, Taniwaki M, Sakai T, Kuroda J.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23 Issue: 6 Pages: 2919-2936
- DOI
  10.3390/ijms23062919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08872, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-21K16246, KAKENHI-PROJECT-21K16274
[Journal Article] Neurolymphomatosis of cranial nerves as the responsible lesions for the vocal cord paralysis and facial nerve palsy in a patient with diffuse large B-cell lymphoma2022
- Author(s)
  Inoue Yu、Hirakawa Koichi、Hayata Hiroki、Nishiyama Daichi、Fujino Takahiro、Tsukamoto Taku、Mizutani Shinsuke、Shimura Yuji、Kuroda Junya
- Journal Title
  
  Annals of Hematology
  
  Volume: 102 Issue: 2 Pages: 481-482
- DOI
  10.1007/s00277-022-05038-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16274
[Journal Article] Clinical Implication of the Effect of the Production of Neutralizing Antibodies Against SARS-Cov-2 for Chronic Immune Thrombocytopenia Flare-Up Associated with COVID-19 Infection: A Case Report and the Review of Literature2022
- Author(s)
  Maekura Chika、Muramatsu Ayako、Nagata Hiroaki、Okamoto Haruya、Onishi Akio、Kato Daishi、Isa Reiko、Fujino Takahiro、Tsukamoto Taku、Mizutani Shinsuke、Shimura Yuji、Kobayashi Tsutomu、Okumura Keita、Inaba Tohru、Nukui Yoko、Kuroda Junya
- Journal Title
  
  Infection and Drug Resistance
  
  Volume: Volume 15 Pages: 2723-2728
- DOI
  10.2147/idr.s360238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16274
[Journal Article] Watchful waiting is an acceptable treatment option for asymptomatic primary ocular adnexal mucosa‐associated lymphoid tissue lymphoma: A retrospective study2022
- Author(s)
  Mizuhara Kentaro, Kobayashi Tsutomu, Nakao Mitsushige, Takahashi Ryoichi, Kaneko Hiroto, Shimura Kazuho, Hirakawa Koichi, Uoshima Nobuhiko, Wada Katsuya, Kawata Eri, Isa Reiko, Fujino Takahiro, Tsukamoto Taku, Mizutani Shinsuke, Shimura Yuji, Yoneda Akiko, Watanabe Akihide, Sotozono Chie, Kuroda Junya
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 3 Pages: 3134-3144
- DOI
  10.1002/cam4.5237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16246, KAKENHI-PROJECT-21K16274
[Journal Article] Paroxysmal nocturnal hemoglobinuria complicated with essential thrombocythemia harboring concomitant PIGA, CALR, and ASXL1 mutations.2021
- Author(s)
  Haruya Okamoto , Nobuhiko Uoshima , Yuri Kamitsuji , Eri Kawata , Yukiko Komori , Nana Sasaki , Yasuhiko Tsutsumi , Taku Tsukamoto , Shinsuke Mizutani , Yasuhito Nannya , Junya Kuroda
- Journal Title
  
  Annals of hematology
  
  Volume: - Issue: 8 Pages: 2113-2115
- DOI
  10.1007/s00277-021-04425-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22854
[Journal Article] Chronic Invasive Fungal Rhinosinusitis with Atypical Clinical Presentation in an Immunocompromised Patient.2020
- Author(s)
  Yuka Kawaji-Kanayama , Ayako Nishimura , Makoto Yasuda , Emiko Sakiyama , Yuji Shimura , Taku Tsukamoto , Tsutomu Kobayashi , Shinsuke Mizutani , Shota Okamoto , Gaku Ohmura , Shigeru Hirano , Eiichi Konishi , Kazutoshi Shibuya , Junya Kuroda
- Journal Title
  
  Infection and drug resistance
  
  Volume: 13 Pages: 3225-3232
- DOI
  10.2147/idr.s273317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22854
[Presentation] RSK/AKT/S6Kトリプル阻害剤 TAS0612の抗骨髄腫効果2023
- Author(s)
  岡本明也、伊佐怜子、村松彩子、水原健太郎、民西(桂川)葉子、金山（川路）悠加、塚本　拓、志村勇司、水谷信介、黒田純也
- Organizer
  第48回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08512
[Presentation] 26.Identification of novel tumour suppressor genes by using genome-wide in vivo CRISPR screening.2022
- Author(s)
  水谷信介, Margaret A Potts, Lin Tai, Andrew J Kueh, Stephen Wilcox, 黒田純也, Andreas Strasser, Marco J Herold.
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16274
[Presentation] Identification of novel tumour suppressor genes using in vivo CRISPR/Cas9 screening2022
- Author(s)
  水谷信介
- Organizer
  The 84rd Annual Meeting of Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-20K22854
[Presentation] Efficacy of salvage therapy with carfilzomib followed by 2nd aPBSCT in relapse myeloma patients2021
- Author(s)
  水谷信介
- Organizer
  第46回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16274
[Presentation] Carfilzomib含有救援療法後2回目の自家末梢血幹細胞移植を実施した再発多発性骨髄腫の検討2021
- Author(s)
  水谷信介, 太田沙絵子, 金山悠加, 服部雄, 井上祐, 村松彩子, 岡本明也, 大西朗生, 水原健太郎, 民西葉子, 伊佐怜子, 山口順子, 藤野貴大, 西山大地, 木元弥生, 塚本拓, 志村勇司, 古林勉, 堀池重夫, 志村和穂, 高橋良一, 兼子裕人, 黒田純也
- Organizer
  第43回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-20K22854

1. 黒田純也 (70433258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 塚本拓 (50825049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Mizutani Shinsuke 水谷 信介

Research Projects

Research Products

Co-Researchers

Identification of pathogenesis-promoting interferon-stimulated genes and development of regulatory strategies in mature B-cell tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of RSK2/AKT/S6K tripple inhibitor for mature lymphoid malignancies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the high-grade pathogenesis of universal mature B cell tumor model by using comprehensive gene editingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation for novel target of aggressive B cell lymphoma by whole genome in vivo CRISPR/Cas9 screeningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myeloma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Treatment with Anti-CD20 Monoclonal Antibody on the Production of Neutralizing Antibody Against Anti?SARS-CoV-2 Vaccination in Mature B-Cell Neoplasms2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Rationale for the Dual-Targeting Therapy for RSK2 and AKT in Multiple Myeloma.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurolymphomatosis of cranial nerves as the responsible lesions for the vocal cord paralysis and facial nerve palsy in a patient with diffuse large B-cell lymphoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical Implication of the Effect of the Production of Neutralizing Antibodies Against SARS-Cov-2 for Chronic Immune Thrombocytopenia Flare-Up Associated with COVID-19 Infection: A Case Report and the Review of Literature2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Watchful waiting is an acceptable treatment option for asymptomatic primary ocular adnexal mucosa‐associated lymphoid tissue lymphoma: A retrospective study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Paroxysmal nocturnal hemoglobinuria complicated with essential thrombocythemia harboring concomitant PIGA, CALR, and ASXL1 mutations.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic Invasive Fungal Rhinosinusitis with Atypical Clinical Presentation in an Immunocompromised Patient.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] RSK/AKT/S6Kトリプル阻害剤 TAS0612の抗骨髄腫効果2023

Author(s)

Organizer

Data Source

[Presentation] 26.Identification of novel tumour suppressor genes by using genome-wide in vivo CRISPR screening.2022

Author(s)

Organizer

Mizutani Shinsuke 水谷信介