Ochi Yotaro 越智陽太郎

Researcher Number	40883707
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 医学研究科, 助教 2020: 京都大学, 医学研究科, 特定助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / 0901:Oncology and related fields
Keywords	Principal Investigator エピジェネティクス / 白血病 / 急性骨髄性白血病 / コヒーシン / クロマチン / エピゲノム / 遺伝子変異

Analysis of the molecular pathogenesis of leukemia based on large-scale epigenomic profilingPrincipal Investigator
- Principal Investigator
  
  越智陽太郎
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Molecular Abnormalities Caused by Mutations in Epigenetic Regulators of LeukemiaPrincipal Investigator
- Principal Investigator
  
  Ochi Yotaro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Elucidation of the pathogenesis of leukemia with cohesin mutations and development of novel treatmentPrincipal Investigator
- Principal Investigator
  
  Ochi Yotaro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kyoto University

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] Medical Science Digest 2021年 2月号2021
- Author(s)
  越智陽太郎
- Total Pages
  53
- Publisher
  ニュー・サイエンス社
- Data Source
  KAKENHI-PROJECT-20K22809
[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ueda Atsushi、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Journal Title
  
  Blood
  
  Volume: 143 Issue: 7 Pages: 604-618
- DOI
  10.1182/blood.2023020857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-21K08393, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-23K24298
[Journal Article] Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms2024
- Author(s)
  Sato Tomohiko、Yoshida Kenichi、...、Matsuo Hidemasa、...、Ito Etsuro
- Journal Title
  
  Blood
  
  Volume: - Issue: 25 Pages: 2627-2643
- DOI
  10.1182/blood.2023022247
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08475, KAKENHI-PROJECT-22K08508, KAKENHI-PROJECT-23K07847, KAKENHI-PROJECT-21K07766, KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-22K16320
[Journal Article] Germ line DDX41 mutations define a unique subtype of myeloid neoplasms2023
- Author(s)
 Makishima H, Saiki R, Nannya Y, (17人省略), Kon A, (28人省略), Maciejewski JP, Ogawa S.
- Journal Title
 
 Blood
 
 Volume: 141 Issue: 5 Pages: 534-549
- DOI
 10.1182/blood.2022018221
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-21K08394, KAKENHI-PROJECT-22K08480, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03712, KAKENHI-PROJECT-22KJ1756, KAKENHI-PROJECT-20K17412, KAKENHI-PROJECT-23K24079
[Journal Article] Clinical significance of clonal evolution in chronic myeloid leukemia2023
- Author(s)
  越智陽太郎
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 64 Issue: 5 Pages: 369-375
- DOI
  10.11406/rinketsu.64.369
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-22K16320
[Journal Article] Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia2022
- Author(s)
 Takeda J, Kenichi Y, (9人省略), Kon A (12/41番目), (途中省略), Makishima H, Ogawa S
- Journal Title
 
 Blood Cancer Discovery
 
 Volume: 3 Issue: 5 Pages: 410-427
- DOI
 10.1158/2643-3230.bcd-21-0192
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-21K08394, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20H03712, KAKENHI-PROJECT-22KJ1756, KAKENHI-PROJECT-20K17412, KAKENHI-PROJECT-23K24079
[Journal Article] Genetic landscape of chronic myeloid leukemia2022
- Author(s)
  Ochi Yotaro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 1 Pages: 30-36
- DOI
  10.1007/s12185-022-03510-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16320
[Journal Article] Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis2021
- Author(s)
  Saiki Ryunosuke、Momozawa Yukihide、Nannya Yasuhito、Nakagawa Masahiro M.、Ochi Yotaro et al
- Journal Title
  
  Nature Medicine
  
  Volume: 27 Issue: 7 Pages: 1239-1249
- DOI
  10.1038/s41591-021-01411-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22809, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053
[Journal Article] Chromatin-Spliceosome Mutations in Acute Myeloid Leukemia2021
- Author(s)
  Ochi Yotaro、Ogawa Seishi
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 6 Pages: 1232-1232
- DOI
  10.3390/cancers13061232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22809
[Journal Article] Molecular classification and diagnostics of upper urinary tract urothelial carcinoma2021
- Author(s)
  藤井陽一、佐藤悠佑、鈴木啓道、川合剛人、森川鉄平、白石友一、中川徹、久米春喜、小川誠司他
- Journal Title
  
  Cancer Cell
  
  Volume: 39 Issue: 6 Pages: 793-809
- DOI
  10.1016/j.ccell.2021.05.008
- NAID
  120007089270
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18576, KAKENHI-PROJECT-20K22809, KAKENHI-INTERNATIONAL-15K21741, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-21K15972, KAKENHI-PROJECT-23K21431
[Journal Article] Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia.2021
- Author(s)
  Ochi Y, Yoshida K, Huang YJ, Kuo MC, Nannya Y, Sasaki K, Mitani K, et al.
- Journal Title
  
  Nat comm
  
  Volume: 12 Issue: 1 Pages: 2833-2833
- DOI
  10.1038/s41467-021-23097-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08822, KAKENHI-PROJECT-20K22809, KAKENHI-INTERNATIONAL-15K21741, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20K08127, KAKENHI-PROJECT-20K08723
[Journal Article] Molecular pathogenesis of myelodysplastic syndromes with concurrent mutations in cohesin STAG2 and transcription factor RUNX12021
- Author(s)
  越智陽太郎
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 62 Issue: 5 Pages: 352-359
- DOI
  10.11406/rinketsu.62.352
- NAID
  130008049792
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22809
[Presentation] コヒーシン遺伝子変異による白血病発症の分子機構2023
- Author(s)
  越智陽太郎
- Organizer
  第二回日本医学会連合Rising Starリトリート
- Data Source
  KAKENHI-PROJECT-22K16320
[Presentation] Molecular mechanism of leukemogenesis caused by cohesin mutations2022
- Author(s)
  Yotaro Ochi, Hiroshi I Suzuki, Seishi Ogawa
- Organizer
  The 81st Annual Meeting of JCA
- Invited
- Data Source
  KAKENHI-PROJECT-22K16320
[Presentation] コヒーシン遺伝子変異によるMDS発症機構2022
- Author(s)
  越智陽太郎
- Organizer
  Advanced Hematology Seminar 2022
- Invited
- Data Source
  KAKENHI-PROJECT-22K16320
[Presentation] Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukemia2022
- Author(s)
  Yotaro Ochi
- Organizer
  Japan Adult Leukemia Study Group 35th Anniversary International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16320
[Presentation] 骨髄性腫瘍の遺伝子変異による転写異常の解明と新規治療法の開発2021
- Author(s)
  越智陽太郎
- Organizer
  日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K22809
[Presentation] Clonal evolution and clinical impact of genetic lesions in blast crisis of chronic myeloid leukemia2021
- Author(s)
  Yotaro Ochi, Kenichi Yoshida, Yasuhito Nannya et al
- Organizer
  日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K22809
[Presentation] Clonal evolution and prognostic impact of mutations in blast crisis of chronic myeloid leukemia2021
- Author(s)
  Yotaro Ochi, Kenichi Yoshida, Yasuhito Nannya etl al
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K22809

1. 滝田順子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 昆彩奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 佐藤悠佑

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 松尾英将

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 三谷絹子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 佐々木光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ochi Yotaro 越智 陽太郎

Research Projects

Research Products

Co-Researchers

Analysis of the molecular pathogenesis of leukemia based on large-scale epigenomic profilingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular Abnormalities Caused by Mutations in Epigenetic Regulators of LeukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of leukemia with cohesin mutations and development of novel treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Medical Science Digest 2021年 2月号2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Germ line <i>DDX41</i> mutations define a unique subtype of myeloid neoplasms2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of clonal evolution in chronic myeloid leukemia2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Amplified <i>EPOR</i>/<i>JAK2</i> Genes Define a Unique Subtype of Acute Erythroid Leukemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic landscape of chronic myeloid leukemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chromatin-Spliceosome Mutations in Acute Myeloid Leukemia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular classification and diagnostics of upper urinary tract urothelial carcinoma2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia.2021

Author(s)

Journal Title

DOI

Data Source

Ochi Yotaro 越智陽太郎