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Ochi Yotaro  越智 陽太郎

ORCIDConnect your ORCID iD *help
Researcher Number 40883707
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 京都大学, 医学研究科, 助教
2020: 京都大学, 医学研究科, 特定助教
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / 0901:Oncology and related fields
Keywords
Principal Investigator
エピジェネティクス / 白血病 / 急性骨髄性白血病 / コヒーシン / クロマチン / エピゲノム / 遺伝子変異
  • Research Projects

    (3 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (6 People)
  •  Analysis of the molecular pathogenesis of leukemia based on large-scale epigenomic profilingPrincipal Investigator

    • Principal Investigator
      越智 陽太郎
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kyoto University
  •  Molecular Abnormalities Caused by Mutations in Epigenetic Regulators of LeukemiaPrincipal Investigator

    • Principal Investigator
      Ochi Yotaro
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kyoto University
  •  Elucidation of the pathogenesis of leukemia with cohesin mutations and development of novel treatmentPrincipal Investigator

    • Principal Investigator
      Ochi Yotaro
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021

All Journal Article Presentation Book

  • [Book] Medical Science Digest 2021年 2月号2021

    • Author(s)
      越智陽太郎
    • Total Pages
      53
    • Publisher
      ニュー・サイエンス社
    • Data Source
      KAKENHI-PROJECT-20K22809
  • [Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024

    • Author(s)
      Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ueda Atsushi、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
    • Journal Title

      Blood

      Volume: 143 Issue: 7 Pages: 604-618

    • DOI

      10.1182/blood.2023020857

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-21K08393, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-23K24298
  • [Journal Article] Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms2024

    • Author(s)
      Sato Tomohiko、Yoshida Kenichi、...、Matsuo Hidemasa、...、Ito Etsuro
    • Journal Title

      Blood

      Volume: - Issue: 25 Pages: 2627-2643

    • DOI

      10.1182/blood.2023022247

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08475, KAKENHI-PROJECT-22K08508, KAKENHI-PROJECT-23K07847, KAKENHI-PROJECT-21K07766, KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-22K16320
  • [Journal Article] Germ line <i>DDX41</i> mutations define a unique subtype of myeloid neoplasms2023

    • Author(s)
      Makishima H, Saiki R, Nannya Y, (17人省略), Kon A, (28人省略), Maciejewski JP, Ogawa S.
    • Journal Title

      Blood

      Volume: 141 Issue: 5 Pages: 534-549

    • DOI

      10.1182/blood.2022018221

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08394, KAKENHI-PROJECT-22K08480, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03712, KAKENHI-PROJECT-22KJ1756, KAKENHI-PROJECT-20K17412, KAKENHI-PROJECT-23K24079
  • [Journal Article] Clinical significance of clonal evolution in chronic myeloid leukemia2023

    • Author(s)
      越智 陽太郎
    • Journal Title

      Rinsho Ketsueki

      Volume: 64 Issue: 5 Pages: 369-375

    • DOI

      10.11406/rinketsu.64.369

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-22K16320
  • [Journal Article] Amplified <i>EPOR</i>/<i>JAK2</i> Genes Define a Unique Subtype of Acute Erythroid Leukemia2022

    • Author(s)
      Takeda J, Kenichi Y, (9人省略), Kon A (12/41番目), (途中省略), Makishima H, Ogawa S
    • Journal Title

      Blood Cancer Discovery

      Volume: 3 Issue: 5 Pages: 410-427

    • DOI

      10.1158/2643-3230.bcd-21-0192

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08394, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20H03712, KAKENHI-PROJECT-22KJ1756, KAKENHI-PROJECT-20K17412, KAKENHI-PROJECT-23K24079
  • [Journal Article] Genetic landscape of chronic myeloid leukemia2022

    • Author(s)
      Ochi Yotaro
    • Journal Title

      International Journal of Hematology

      Volume: 117 Issue: 1 Pages: 30-36

    • DOI

      10.1007/s12185-022-03510-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16320
  • [Journal Article] Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis2021

    • Author(s)
      Saiki Ryunosuke、Momozawa Yukihide、Nannya Yasuhito、Nakagawa Masahiro M.、Ochi Yotaro et al
    • Journal Title

      Nature Medicine

      Volume: 27 Issue: 7 Pages: 1239-1249

    • DOI

      10.1038/s41591-021-01411-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K22809, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053
  • [Journal Article] Chromatin-Spliceosome Mutations in Acute Myeloid Leukemia2021

    • Author(s)
      Ochi Yotaro、Ogawa Seishi
    • Journal Title

      Cancers

      Volume: 13 Issue: 6 Pages: 1232-1232

    • DOI

      10.3390/cancers13061232

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K22809
  • [Journal Article] Molecular classification and diagnostics of upper urinary tract urothelial carcinoma2021

    • Author(s)
      藤井陽一、佐藤悠佑、鈴木啓道、川合剛人、森川鉄平、白石友一、中川徹、久米春喜、小川誠司他
    • Journal Title

      Cancer Cell

      Volume: 39 Issue: 6 Pages: 793-809

    • DOI

      10.1016/j.ccell.2021.05.008

    • NAID

      120007089270

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18576, KAKENHI-PROJECT-20K22809, KAKENHI-INTERNATIONAL-15K21741, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-21K15972, KAKENHI-PROJECT-23K21431
  • [Journal Article] Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia.2021

    • Author(s)
      Ochi Y, Yoshida K, Huang YJ, Kuo MC, Nannya Y, Sasaki K, Mitani K, et al.
    • Journal Title

      Nat comm

      Volume: 12 Issue: 1 Pages: 2833-2833

    • DOI

      10.1038/s41467-021-23097-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08822, KAKENHI-PROJECT-20K22809, KAKENHI-INTERNATIONAL-15K21741, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20K08127, KAKENHI-PROJECT-20K08723
  • [Journal Article] Molecular pathogenesis of myelodysplastic syndromes with concurrent mutations in cohesin STAG2 and transcription factor RUNX12021

    • Author(s)
      越智 陽太郎
    • Journal Title

      Rinsho Ketsueki

      Volume: 62 Issue: 5 Pages: 352-359

    • DOI

      10.11406/rinketsu.62.352

    • NAID

      130008049792

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K22809
  • [Presentation] コヒーシン遺伝子変異による白血病発症の分子機構2023

    • Author(s)
      越智陽太郎
    • Organizer
      第二回日本医学会連合Rising Starリトリート
    • Data Source
      KAKENHI-PROJECT-22K16320
  • [Presentation] Molecular mechanism of leukemogenesis caused by cohesin mutations2022

    • Author(s)
      Yotaro Ochi, Hiroshi I Suzuki, Seishi Ogawa
    • Organizer
      The 81st Annual Meeting of JCA
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K16320
  • [Presentation] コヒーシン遺伝子変異によるMDS発症機構2022

    • Author(s)
      越智陽太郎
    • Organizer
      Advanced Hematology Seminar 2022
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K16320
  • [Presentation] Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukemia2022

    • Author(s)
      Yotaro Ochi
    • Organizer
      Japan Adult Leukemia Study Group 35th Anniversary International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16320
  • [Presentation] 骨髄性腫瘍の遺伝子変異による転写異常の解明と新規治療法の開発2021

    • Author(s)
      越智陽太郎
    • Organizer
      日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K22809
  • [Presentation] Clonal evolution and clinical impact of genetic lesions in blast crisis of chronic myeloid leukemia2021

    • Author(s)
      Yotaro Ochi, Kenichi Yoshida, Yasuhito Nannya et al
    • Organizer
      日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K22809
  • [Presentation] Clonal evolution and prognostic impact of mutations in blast crisis of chronic myeloid leukemia2021

    • Author(s)
      Yotaro Ochi, Kenichi Yoshida, Yasuhito Nannya etl al
    • Organizer
      日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K22809
  • 1.  滝田 順子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  昆 彩奈
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  佐藤 悠佑
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  松尾 英将
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  三谷 絹子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  佐々木 光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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