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Kobayashi Minoru  小林 実

ORCIDConnect your ORCID iD *help
Researcher Number 40885547
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2023: 東北大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields
Keywords
Principal Investigator
家族性大腸腺腫症 / デオキシコール酸 / 大腸癌 / Wntシグナル / MRP3 / ABCC3 / ROS / 活性酸素種 / NSAIDs / DCA … More / FAP / MAPKシグナル / オルガノイド / 二次胆汁酸 / 胆汁酸 / ABCトランスポーター Less
  • Research Projects

    (2 results)
  • Research Products

    (2 results)
  •  Investigation of the mechanism for suppression of carcinogenesis in familial adenomatous polyposis mediated by ABCC3 and ROS with NSAIDs.Principal Investigator

    • Principal Investigator
      Minoru Kobayashi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Tohoku University
  •  Elucidation of a novel mechanism of colon carcinogenesis mediated by ABCC3 and bile acids via Wnt signaling pathwayPrincipal Investigator

    • Principal Investigator
      Kobayashi Minoru
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Tohoku University

All 2024

All Journal Article Presentation

  • [Journal Article] Downregulation of <scp>ABCC3</scp> activates <scp>MAPK</scp> signaling through accumulation of deoxycholic acid in colorectal cancer cells2024

    • Author(s)
      Sato Yukihiro、Kobayashi Minoru、Ohira Masahiro、Funayama Ryo、Maekawa Masamitsu、Karasawa Hideaki、Kashiwagi Ryosuke、Aoyama Yayoi、Mano Nariyasu、Ohnuma Shinobu、Unno Michiaki、Nakayama Keiko
    • Journal Title

      Cancer Science

      Volume: Online ahead of print Issue: 6 Pages: 1778-1790

    • DOI

      10.1111/cas.16132

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15477, KAKENHI-PROJECT-21H02458
  • [Presentation] ABCC3 (MRP3)-mediated export of deoxycholic acid (DCA) regulates MAPK signaling in colorectal adenoma and adenocarcinoma2024

    • Author(s)
      Yukihiro Sato、Minoru Kobayashi、Masahiro Ohira、Ryo Funayama、Masamitsu Maekawa、Hideaki Karasawa、Shinobu Ohnuma、Michiaki Unno、Keiko Nakayama
    • Organizer
      AACR ANNUAL MEETING 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15477

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