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Shibata Shun  柴田 峻

ORCIDConnect your ORCID iD *help
Researcher Number 40885670
Other IDs
Affiliation (Current) 2025: 東北大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help 2020 – 2024: 東北大学, 医学系研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 44020:Developmental biology-related / Transformative Research Areas, Section (III) / 0701:Biology at molecular to cellular levels, and related fields
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords
Principal Investigator
オルガノイド / 着床 / 胎盤発生 / TS細胞 / ES細胞 / 母子間相互作用 / マイクロ流路デバイス / 免疫寛容 / ES細胞 / 子宮内膜 … More / 胚体外系譜 / ヒトTS細胞 / Hippo-YAPシグナル / ヒトTS細胞 … More
Except Principal Investigator
妊娠高血圧症候群 / ヒト胎盤 / CRISPRスクリーニング / 転写因子 / ヒト胎盤幹細胞 / 数理モデル / シングル細胞マルチオーム解析 / 胚着床モデル / 免疫寛容 / 着床障害 / 妊娠合併症 / 幹細胞 / 妊娠高血圧腎症 / 栄養膜幹細胞 / CRISPR / 栄養膜幹細胞(TS細胞) / 胎盤 / 母体ー胎児間相互作用 / 母体-胎児間相互作用 / オルガノイド / 胎盤幹細胞 Less
  • Research Projects

    (8 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (6 People)
  •  三次元多階層細胞モデルを駆使した着床免疫パラダイムの深層解明Principal Investigator

    • Principal Investigator
      柴田 峻
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Tohoku University
  •  ヒト胚着床オルガノイドモデルを活用した母子間競合的細胞コミュニケーションの解析Principal Investigator

    • Principal Investigator
      柴田 峻
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tohoku University
  •  Implantation organoid model using human multilevel stem cells and elucidation of immune tolerance mechanism

    • Principal Investigator
      有馬 隆博
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Tohoku University
  •  ヒト胎盤の発生・分化を調節する分子メカニズムと疾患の病態解明

    • Principal Investigator
      小林 枝里
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tohoku University
  •  ヒト胎盤形成のエピゲノム制御と母体-胎盤間分子シグナルコミュニケーションの理解

    • Principal Investigator
      有馬 隆博
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Tohoku University
  •  Innovative disease modeling of pregnancy complications using human trophoblast stem cells

    • Principal Investigator
      Okae Hiroaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Kumamoto University
      Tohoku University
  •  Creation of a Stem Cell-based Organoids for Visualizing Human Embryonic DevelopmentPrincipal Investigator

    • Principal Investigator
      Shibata Shun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Tohoku University
  •  Investigation of the role of Hippo-YAP signals regulating extraembryonic lineagesPrincipal Investigator

    • Principal Investigator
      Shibata Shun
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0701:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Tohoku University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

  • [Book] 産婦人科の実際2023

    • Author(s)
      柴田 峻, 小林 枝里, 有馬 隆博
    • Total Pages
      6
    • Publisher
      金原出版(株)
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Book] 産婦人科の実際2023

    • Author(s)
      柴田 峻, 小林 枝里, 有馬 隆博
    • Total Pages
      870
    • Publisher
      金原出版(株)
    • Data Source
      KAKENHI-PROJECT-21H04834
  • [Book] 産婦人科の実際2023

    • Author(s)
      柴田峻, 小林枝里, 有馬隆博.
    • Total Pages
      6
    • Publisher
      金原出版株式会社
    • Data Source
      KAKENHI-PROJECT-23K08838
  • [Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

    • Author(s)
      大池 輝, 小林 枝里, 小林 記緒, 柴田 峻, 岡江 寛明, 北村 茜, 宮内 尚子, 有馬 隆博
    • Total Pages
      5
    • Publisher
      北隆館/ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-20K22615
  • [Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

    • Author(s)
      大池 輝, 小林 枝里, 小林 記緒, 柴田 峻, 岡江 寛明, 北村 茜, 宮内 尚子, 有馬 隆博
    • Total Pages
      5
    • Publisher
      北隆館/ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-21H04834
  • [Book] ヒト胎盤発生と幹細胞2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Total Pages
      5
    • Publisher
      医学書院(金原出版)
    • Data Source
      KAKENHI-PROJECT-21H04834
  • [Book] ヒト胎盤発生と幹細胞2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Total Pages
      5
    • Publisher
      医学書院(金原出版)
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

    • Author(s)
      大池 輝, 小林 枝里, 小林 記緒, 柴田 峻, 岡江 寛明, 北村 茜, 宮内 尚子, 有馬 隆博
    • Total Pages
      5
    • Publisher
      北隆館/ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-21H03072
  • [Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

    • Author(s)
      大池 輝, 小林 枝里, 小林 記緒, 柴田 峻, 岡江 寛明, 北村 茜, 宮内 尚子, 有馬 隆博
    • Total Pages
      5
    • Publisher
      北隆館/ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Book] ヒト胎盤発生と幹細胞2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Total Pages
      5
    • Publisher
      医学書院(金原出版)
    • Data Source
      KAKENHI-PROJECT-20K22615
  • [Book] ヒト胎盤発生と幹細胞2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Total Pages
      5
    • Publisher
      医学書院(金原出版)
    • Data Source
      KAKENHI-PROJECT-21H03072
  • [Journal Article] Trophoblast stem cell-based organoid models of the human placental barrier2024

    • Author(s)
      Hori Takeshi、Okae Hiroaki、Shibata Shun、Kobayashi Norio、Kobayashi Eri H.、Oike Akira、Sekiya Asato、Arima Takahiro、Kaji Hirokazu
    • Journal Title

      Nature Communications

      Volume: 15 Issue: 1 Pages: 1-1

    • DOI

      10.1038/s41467-024-45279-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
  • [Journal Article] Modeling embryo-endometrial interface recapitulating human embryo implantation2024

    • Author(s)
      Shibata Shun、Endo Shun、Nagai Luis A. E.、H. Kobayashi Eri、Oike Akira、Kobayashi Norio、Kitamura Akane、Hori Takeshi、Nashimoto Yuji、Nakato Ryuichiro、Hamada Hirotaka、Kaji Hirokazu、Kikutake Chie、Suyama Mikita、Saito Masatoshi、Yaegashi Nobuo、Okae Hiroaki、Arima Takahiro
    • Journal Title

      Science Advances

      Volume: 10 Issue: 8

    • DOI

      10.1126/sciadv.adi4819

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21H03803, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
  • [Journal Article] CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development2023

    • Author(s)
      Takanori Shimizu*, Akira Oike*, Eri H. Kobayashi*, Asato Sekiya, Norio Kobayashi, Shun Shibata, Hirotaka Hamada, Masatoshi Saito, Nobuo Yaegashi, Mikita Suyama, Takahiro Arima, and Hiroaki Okae. *T.S., A.O., and E.H.K. contributed equally to this work.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 120 Issue: 51

    • DOI

      10.1073/pnas.2311372120

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K08838, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
  • [Journal Article] Genomic imprinting in human placentation2022

    • Author(s)
      Kobayashi Eri H.、Shibata Shun、Oike Akira、Kobayashi Norio、Hamada Hirotaka、Okae Hiroaki、Arima Takahiro
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 21 Issue: 1

    • DOI

      10.1002/rmb2.12490

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
  • [Journal Article] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022

    • Author(s)
      Kobayashi Norio、Okae Hiroaki、Hiura Hitoshi、Kubota Naoto、Kobayashi Eri H.、Shibata Shun、Oike Akira、Hori Takeshi、Kikutake Chie、Hamada Hirotaka、Kaji Hirokazu、Suyama Mikita、Bortolin-Cavaill? Marie-Line、Cavaill? J?r?me、Arima Takahiro
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 3071-3071

    • DOI

      10.1038/s41467-022-30775-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-22K15117, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05757
  • [Journal Article] Unique features and emerging in vitro models of human placental development.2020

    • Author(s)
      Shun Shibata, Eri H Kobayashi, Norio Kobayashi, Akira Oike, Hiroaki Okae, Takahiro Arima.
    • Journal Title

      Reprod Med Biol .

      Volume: 12 Issue: 4 Pages: 301-313

    • DOI

      10.1002/rmb2.12347

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16135, KAKENHI-PROJECT-20K22615, KAKENHI-PROJECT-20K22943, KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
  • [Presentation] Modeling Embryo Endometrial Interface Recapitulating Human Embryo Implantation2023

    • Author(s)
      Shun Shibata, Luis A. E. Nagai, Akira Oike, Eri H. Kobayashi, Norio Kobayashi, Ryuichiro Nakato, Mikita Suyama, Hiroaki Okae, Takahiro Arima
    • Organizer
      IHEC Annual Meeting 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Presentation] 胎児-母体アセンブロイドを用いたin vitroにおけるヒト胚着床現象の再現2023

    • Author(s)
      柴田 峻, 遠藤俊, 大池輝, 小林枝里, Luis Augusto Eijy Nagai, 中戸隆一郎, 岡江寛明, 有馬隆博
    • Organizer
      第41回日本受精着床学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Presentation] 胎児-母体アセンブロイドを用いたin vitroにおけるヒト胚着床現象の再現2023

    • Author(s)
      柴田 峻, 遠藤俊, 大池輝, 小林枝里, Luis Augusto Eijy Nagai, 中戸隆一郎, 岡江寛明, 有馬隆博
    • Organizer
      第41回日本受精着床学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21H04834
  • [Presentation] ヒト胎盤発生過程におけるエピジェネティクス制御と疾患との関連-ヒトTS細胞を用いた基礎的な研究-2023

    • Author(s)
      有馬 隆博、柴田峻
    • Organizer
      第43回日本妊娠高血圧学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Presentation] Modeling Embryo Endometrial Interface Recapitulating Human Embryo Implantation2023

    • Author(s)
      Shun Shibata, Luis A. E. Nagai, Akira Oike, Eri H. Kobayashi, Norio Kobayashi, Ryuichiro Nakato, Mikita Suyama, Hiroaki Okae, Takahiro Arima
    • Organizer
      IHEC Annual Meeting 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04834
  • [Presentation] マルチオミックス解析による妊娠高血圧症候群の胎盤特性2022

    • Author(s)
      遠藤俊, 柴田峻, 大池輝, 小林枝里, 岡江寛明, 有馬隆博
    • Organizer
      第30回日本胎盤学会学術集会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Presentation] マルチオミックス解析による妊娠高血圧症候群の胎盤特性2022

    • Author(s)
      遠藤俊, 柴田峻, 大池輝, 小林枝里, 岡江寛明, 有馬隆博
    • Organizer
      第30回日本胎盤学会学術集会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04834
  • [Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Organizer
      ART FORUM’21 生殖の分子機構への新たなアプローチ
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04834
  • [Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Organizer
      ART FORUM’21 生殖の分子機構への新たなアプローチ
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K22615
  • [Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Organizer
      ART FORUM’21 生殖の分子機構への新たなアプローチ
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15098
  • [Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021

    • Author(s)
      柴田峻、岡江寛明、有馬隆博
    • Organizer
      ART FORUM’21 生殖の分子機構への新たなアプローチ
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03072
  • 1.  Okae Hiroaki (10582695)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  有馬 隆博 (80253532)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 3.  小林 枝里 (70634971)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 4.  小林 記緒 (10803885)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  堀 武志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 6.  梶 弘和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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