Shibata Shun 柴田峻

Researcher Number	40885670
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 東北大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related / Transformative Research Areas, Section (III) / 0701:Biology at molecular to cellular levels, and related fields Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator オルガノイド / 着床 / 胎盤発生 / TS細胞 / ES細胞 / 母子間相互作用 / マイクロ流路デバイス / 免疫寛容 / ＥＳ細胞 / 子宮内膜 … More / 胚体外系譜 / ヒトTS細胞 / Hippo-YAPシグナル / ヒトＴＳ細胞 … More Except Principal Investigator 妊娠高血圧症候群 / ヒト胎盤 / CRISPRスクリーニング / 転写因子 / ヒト胎盤幹細胞 / 数理モデル / シングル細胞マルチオーム解析 / 胚着床モデル / 免疫寛容 / 着床障害 / 妊娠合併症 / 幹細胞 / 妊娠高血圧腎症 / 栄養膜幹細胞 / CRISPR / 栄養膜幹細胞（TS細胞） / 胎盤 / 母体ー胎児間相互作用 / 母体-胎児間相互作用 / オルガノイド / 胎盤幹細胞 Less

三次元多階層細胞モデルを駆使した着床免疫パラダイムの深層解明Principal Investigator
- Principal Investigator
  
  柴田峻
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Tohoku University
ヒト胚着床オルガノイドモデルを活用した母子間競合的細胞コミュニケーションの解析Principal Investigator
- Principal Investigator
  
  柴田峻
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tohoku University
Implantation organoid model using human multilevel stem cells and elucidation of immune tolerance mechanism
- Principal Investigator
  
  有馬隆博
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
ヒト胎盤の発生・分化を調節する分子メカニズムと疾患の病態解明
- Principal Investigator
  
  小林枝里
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
ヒト胎盤形成のエピゲノム制御と母体－胎盤間分子シグナルコミュニケーションの理解
- Principal Investigator
  
  有馬隆博
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
Innovative disease modeling of pregnancy complications using human trophoblast stem cells
- Principal Investigator
  
  Okae Hiroaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kumamoto University
  Tohoku University
Creation of a Stem Cell-based Organoids for Visualizing Human Embryonic DevelopmentPrincipal Investigator
- Principal Investigator
  
  Shibata Shun
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Tohoku University
Investigation of the role of Hippo-YAP signals regulating extraembryonic lineagesPrincipal Investigator
- Principal Investigator
  
  Shibata Shun
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  Tohoku University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] 産婦人科の実際2023
- Author(s)
  柴田峻, 小林枝里, 有馬隆博
- Total Pages
  6
- Publisher
  金原出版(株)
- Data Source
  KAKENHI-PROJECT-21K15098
[Book] 産婦人科の実際2023
- Author(s)
  柴田峻, 小林枝里, 有馬隆博
- Total Pages
  870
- Publisher
  金原出版(株)
- Data Source
  KAKENHI-PROJECT-21H04834
[Book] 産婦人科の実際2023
- Author(s)
  柴田峻, 小林枝里, 有馬隆博.
- Total Pages
  6
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-23K08838
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K22615
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21H04834
[Book] ヒト胎盤発生と幹細胞2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Total Pages
  5
- Publisher
  医学書院(金原出版）
- Data Source
  KAKENHI-PROJECT-21H04834
[Book] ヒト胎盤発生と幹細胞2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Total Pages
  5
- Publisher
  医学書院(金原出版）
- Data Source
  KAKENHI-PROJECT-21K15098
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21H03072
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K15098
[Book] ヒト胎盤発生と幹細胞2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Total Pages
  5
- Publisher
  医学書院(金原出版）
- Data Source
  KAKENHI-PROJECT-20K22615
[Book] ヒト胎盤発生と幹細胞2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Total Pages
  5
- Publisher
  医学書院(金原出版）
- Data Source
  KAKENHI-PROJECT-21H03072
[Journal Article] Trophoblast stem cell-based organoid models of the human placental barrier2024
- Author(s)
  Hori Takeshi、Okae Hiroaki、Shibata Shun、Kobayashi Norio、Kobayashi Eri H.、Oike Akira、Sekiya Asato、Arima Takahiro、Kaji Hirokazu
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41467-024-45279-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
[Journal Article] Modeling embryo-endometrial interface recapitulating human embryo implantation2024
- Author(s)
  Shibata Shun、Endo Shun、Nagai Luis A. E.、H. Kobayashi Eri、Oike Akira、Kobayashi Norio、Kitamura Akane、Hori Takeshi、Nashimoto Yuji、Nakato Ryuichiro、Hamada Hirotaka、Kaji Hirokazu、Kikutake Chie、Suyama Mikita、Saito Masatoshi、Yaegashi Nobuo、Okae Hiroaki、Arima Takahiro
- Journal Title
  
  Science Advances
  
  Volume: 10 Issue: 8
- DOI
  10.1126/sciadv.adi4819
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21H03803, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
[Journal Article] CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development2023
- Author(s)
  Takanori Shimizu*, Akira Oike*, Eri H. Kobayashi*, Asato Sekiya, Norio Kobayashi, Shun Shibata, Hirotaka Hamada, Masatoshi Saito, Nobuo Yaegashi, Mikita Suyama, Takahiro Arima, and Hiroaki Okae. *T.S., A.O., and E.H.K. contributed equally to this work.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 51
- DOI
  10.1073/pnas.2311372120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08838, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] Genomic imprinting in human placentation2022
- Author(s)
  Kobayashi Eri H.、Shibata Shun、Oike Akira、Kobayashi Norio、Hamada Hirotaka、Okae Hiroaki、Arima Takahiro
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 21 Issue: 1
- DOI
  10.1002/rmb2.12490
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022
- Author(s)
  Kobayashi Norio、Okae Hiroaki、Hiura Hitoshi、Kubota Naoto、Kobayashi Eri H.、Shibata Shun、Oike Akira、Hori Takeshi、Kikutake Chie、Hamada Hirotaka、Kaji Hirokazu、Suyama Mikita、Bortolin-Cavaill? Marie-Line、Cavaill? J?r?me、Arima Takahiro
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 3071-3071
- DOI
  10.1038/s41467-022-30775-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-22K15117, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05757
[Journal Article] Unique features and emerging in vitro models of human placental development.2020
- Author(s)
  Shun Shibata, Eri H Kobayashi, Norio Kobayashi, Akira Oike, Hiroaki Okae, Takahiro Arima.
- Journal Title
  
  Reprod Med Biol .
  
  Volume: 12 Issue: 4 Pages: 301-313
- DOI
  10.1002/rmb2.12347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16135, KAKENHI-PROJECT-20K22615, KAKENHI-PROJECT-20K22943, KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
[Presentation] Modeling Embryo Endometrial Interface Recapitulating Human Embryo Implantation2023
- Author(s)
  Shun Shibata, Luis A. E. Nagai, Akira Oike, Eri H. Kobayashi, Norio Kobayashi, Ryuichiro Nakato, Mikita Suyama, Hiroaki Okae, Takahiro Arima
- Organizer
  IHEC Annual Meeting 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15098
[Presentation] 胎児-母体アセンブロイドを用いたin vitroにおけるヒト胚着床現象の再現2023
- Author(s)
  柴田峻, 遠藤俊, 大池輝, 小林枝里, Luis Augusto Eijy Nagai, 中戸隆一郎, 岡江寛明, 有馬隆博
- Organizer
  第41回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-21K15098
[Presentation] 胎児-母体アセンブロイドを用いたin vitroにおけるヒト胚着床現象の再現2023
- Author(s)
  柴田峻, 遠藤俊, 大池輝, 小林枝里, Luis Augusto Eijy Nagai, 中戸隆一郎, 岡江寛明, 有馬隆博
- Organizer
  第41回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] ヒト胎盤発生過程におけるエピジェネティクス制御と疾患との関連－ヒトTS細胞を用いた基礎的な研究－2023
- Author(s)
  有馬隆博、柴田峻
- Organizer
  第43回日本妊娠高血圧学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15098
[Presentation] Modeling Embryo Endometrial Interface Recapitulating Human Embryo Implantation2023
- Author(s)
  Shun Shibata, Luis A. E. Nagai, Akira Oike, Eri H. Kobayashi, Norio Kobayashi, Ryuichiro Nakato, Mikita Suyama, Hiroaki Okae, Takahiro Arima
- Organizer
  IHEC Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] マルチオミックス解析による妊娠高血圧症候群の胎盤特性2022
- Author(s)
  遠藤俊, 柴田峻, 大池輝, 小林枝里, 岡江寛明, 有馬隆博
- Organizer
  第30回日本胎盤学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15098
[Presentation] マルチオミックス解析による妊娠高血圧症候群の胎盤特性2022
- Author(s)
  遠藤俊, 柴田峻, 大池輝, 小林枝里, 岡江寛明, 有馬隆博
- Organizer
  第30回日本胎盤学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Organizer
  ART FORUM’21 生殖の分子機構への新たなアプローチ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834
[Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Organizer
  ART FORUM’21 生殖の分子機構への新たなアプローチ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22615
[Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Organizer
  ART FORUM’21 生殖の分子機構への新たなアプローチ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15098
[Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Organizer
  ART FORUM’21 生殖の分子機構への新たなアプローチ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03072

1. Okae Hiroaki (10582695)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 有馬隆博 (80253532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 小林枝里 (70634971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 小林記緒 (10803885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 堀武志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 梶弘和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Shibata Shun 柴田 峻

Research Projects

Research Products

Co-Researchers

三次元多階層細胞モデルを駆使した着床免疫パラダイムの深層解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト胚着床オルガノイドモデルを活用した母子間競合的細胞コミュニケーションの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Implantation organoid model using human multilevel stem cells and elucidation of immune tolerance mechanism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト胎盤の発生・分化を調節する分子メカニズムと疾患の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト胎盤形成のエピゲノム制御と母体－胎盤間分子シグナルコミュニケーションの理解

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Innovative disease modeling of pregnancy complications using human trophoblast stem cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of a Stem Cell-based Organoids for Visualizing Human Embryonic DevelopmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the role of Hippo-YAP signals regulating extraembryonic lineagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 産婦人科の実際2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 産婦人科の実際2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 産婦人科の実際2023

Author(s)

Total Pages

Publisher

Data Source

[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

Author(s)

Total Pages

Publisher

Data Source

[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

Author(s)

Total Pages

Publisher

Data Source

[Book] ヒト胎盤発生と幹細胞2021

Author(s)

Total Pages

Shibata Shun 柴田峻