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SHIROMOTO Yusuke  城本 悠助

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Shiromoto Yusuke  城本 悠助

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Researcher Number 40912259
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help 2021 – 2025: 京都大学, 医学研究科, 特定助教
2023: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 49030:Experimental pathology-related / 0702:Biology at cellular to organismal levels, and related fields
Keywords
Principal Investigator
精子幹細胞 / piRNA / 化合物スクリーニング / 生殖細胞腫瘍 / 精子形成 / DNA損傷 / R-loop / 精巣
  • Research Projects

    (4 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (1 People)
  •  精子幹細胞を用いた生殖細胞におけるウイルス感染の防御システムの解明Principal Investigator

    • Principal Investigator
      城本 悠助
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  Exploration of compounds regulating piRNA pathways using spermatogonial stem cells and regulation of piRNA pathways in the testis.Principal Investigator

    • Principal Investigator
      城本 悠助
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  piRNAを介した生殖細胞の脱分化・腫瘍化制御機構の解明Principal Investigator

    • Principal Investigator
      城本 悠助
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  The Mechanism of R-loop resolution in male germ cells and its effects on spermatogenesis and next generation.Principal Investigator

    • Principal Investigator
      Shiromoto Yusuke
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0702:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Kyoto University

All 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] Intracytoplasmic sperm injection induces transgenerational abnormalities in mice.2023

    • Author(s)
      Kanatsu-Shinohara M, Shiromoto Y, Ogonuki N, Inoue K, Hattori S, Miura K, Watanabe N, Hasegawa A, Mochida K, Yamamoto T, Miyakawa T, Ogura A, Shinohara T.
    • Journal Title

      J Clin Invest

      Volume: 133 Issue: 22

    • DOI

      10.1172/jci170140

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19429, KAKENHI-PROJECT-23K14117, KAKENHI-PROJECT-22K07003, KAKENHI-PROJECT-23K05622, KAKENHI-PROJECT-23K05860, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23H00399
  • [Journal Article] ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16INK4a levels2022

    • Author(s)
      Hao Xue、Shiromoto Yusuke、Sakurai Masayuki、Towers Martina、Zhang Qiang、Wu Shuai、Havas Aaron、Wang Lu、Berger Shelley、Adams Peter D.、Tian Bin、Nishikura Kazuko、Kossenkov Andrew V.、Liu Pingyu、Zhang Rugang
    • Journal Title

      Nature Cell Biology

      Volume: 24 Issue: 8 Pages: 1202-1210

    • DOI

      10.1038/s41556-022-00959-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K20655
  • [Presentation] Intracytoplasmic sperm injection induces transgenerational abnormalities in mice2024

    • Author(s)
      城本 悠助
    • Organizer
      2023年度 先端モデル動物支援プラットフォーム成果発表会
    • Data Source
      KAKENHI-PROJECT-22K07003
  • 1.  篠原 隆司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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