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Omiya Shigemiki  大宮 茂幹

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… Alternative Names

大宮 茂幹  オオミヤ シゲミキ

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Researcher Number 40920260
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立循環器病研究センター, 研究所, 部長
Affiliation (based on the past Project Information) *help 2022 – 2023: 国立研究開発法人国立循環器病研究センター, 研究所, 部長
Review Section/Research Field
Principal Investigator
Medicine, Dentistry, and Pharmacy
Except Principal Investigator
Basic Section 53020:Cardiology-related
Keywords
Principal Investigator
サイトカインmRNA / 心臓線維芽細胞 / 心筋細胞 / インフラマソーム / サイトカイン / メチル化 / ミトコンドリアDNA / 心不全 / 自然炎症
Except Principal Investigator
薬剤スクリーニング … More / IPS細胞 / ハイスループットスクリーニング / iPS 細胞 / ダノン病 Less
  • Research Projects

    (2 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (4 People)
  •  ダノン病に対する新規治療薬の探索

    • Principal Investigator
      中西 千明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  自然炎症に起因する心不全発症進展メカニズムの解明と治療標的の同定Principal Investigator

    • Principal Investigator
      大宮 茂幹
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research)
    • Review Section
      Medicine, Dentistry, and Pharmacy
    • Research Institution
      National Cardiovascular Center Research Institute

All 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 342023

    • Author(s)
      Sugihara Ryuta、Taneike Manabu、Murakawa Tomokazu、Tamai Takahito、Ueda Hiromichi、Kitazume-Taneike Rika、Oka Takafumi、Akazawa Yasuhiro、Nishida Hiroki、Mine Kentaro、Hioki Ayana、Omi Jumpei、Omiya Shigemiki、Aoki Junken、Ikeda Kazutaka、Nishida Kazuhiko、Arita Makoto、Yamaguchi Osamu、Sakata Yasushi、Otsu Kinya
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 4494-4494

    • DOI

      10.1038/s41467-023-40201-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K21350, KAKENHI-PROJECT-20K08491, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-22H00438
  • [Journal Article] Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload2022

    • Author(s)
      Akazawa Yasuhiro、Taneike Manabu、Ueda Hiromichi、Kitazume-Taneike Rika、Murakawa Tomokazu、Sugihara Ryuta、Yorifuji Hiroki、Nishida Hiroki、Mine Kentaro、Hioki Ayana、Omiya Shigemiki、Nakayama Hiroyuki、Yamaguchi Osamu、Yoshimori Tamotsu、Sakata Yasushi、Otsu Kinya
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 41-41

    • DOI

      10.1038/s41598-021-03920-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02913, KAKENHI-PROJECT-20K08448, KAKENHI-PROJECT-20K08491, KAKENHI-PROJECT-21K08104, KAKENHI-PROJECT-21K21350
  • [Presentation] Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure2024

    • Author(s)
      Shigemiki Omiya
    • Organizer
      第40回国際心臓研究学会日本部会/第7回日本循環器学会基礎研究フォーラム/第31回日本血管生物医学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K21350
  • [Presentation] Tristetraprolin in cardiomyocytes has a protective role in pressure-overloaded hearts2023

    • Author(s)
      Shigemiki Omiya
    • Organizer
      European Society of Cardiology Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K21350
  • [Presentation] Sustained Increase in Cytokine mRNA in Cardiomyocytes Contributes to Cardiomyocyte Death and Inflammation in the Development of Heart Failure2023

    • Author(s)
      大宮茂幹
    • Organizer
      第87回日本循環器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K21350
  • [Presentation] フェリチン特異的オートファジーが寄与する心不全発症メカニズム2023

    • Author(s)
      大宮茂幹
    • Organizer
      第71回日本心臓病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K21350
  • 1.  中西 千明 (80623660)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  YAMAGUCHI Osamu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  大津 欣也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  種池 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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