JIN Chunhuan 金春奐

… Alternative Names

金春奐ジンチュンファン

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Researcher Number	40981600
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院医学系研究科, 特任助教(常勤) 2023: 大阪大学, 大学院医学系研究科, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / 0802:Biomedical structure and function and related fields
Keywords	Principal Investigator PK-PD / 結合滞留時間 / リガンド結合構造 / 阻害薬 / トランスポーター

Research Projects
(2 results)
Research Products
(5 results)

アミノ酸輸送体阻害薬の標的結合構造に基づく新たな輸送体活性制御機構の解明Principal Investigator
- Principal Investigator
  
  金春奐
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  The University of Osaka
アミノ酸輸送体阻害薬の結合滞留時間／持続抑制効果の構造基盤と薬理学的意義の解明Principal Investigator
- Principal Investigator
  
  金春奐
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0802:Biomedical structure and function and related fields
- Research Institution
  Osaka University

All 2024 2023

All Journal Article Presentation

[Journal Article] Structure activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1)2024
- Author(s)
  Chen Sihui、Jin Chunhuan、Ohgaki Ryuichi、Xu Minhui、Okanishi Hiroki、Kanai Yoshikatsu
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-024-55252-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
[Journal Article] Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells2024
- Author(s)
  Ma Yu、Okuda Suguru、Okanishi Hiroki、Xu Minhui、Jin Chunhuan、Endou Hitoshi、Ohgaki Ryuichi、Kanai Yoshikatsu
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 155 Issue: 1 Pages: 14-20
- DOI
  10.1016/j.jphs.2024.03.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
[Journal Article] Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation2024
- Author(s)
  Zhou Xinyu、Ohgaki Ryuichi、Jin Chunhuan、Xu Minhui、Okanishi Hiroki、Endou Hitoshi、Kanai Yoshikatsu
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 3 Pages: 182-191
- DOI
  10.1016/j.jphs.2024.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
[Journal Article] The NERP-4-SNAT2 axis regulates pancreatic β-cell maintenance and function2023
- Author(s)
  Zhang Weidong、Miura Ayako、Abu Saleh Md Moin、Shimizu Koichiro、Mita Yuichiro、Tanida Ryota、Hirako Satoshi、Shioda Seiji、Gmyr Valery、Kerr-Conte Julie、Pattou Francois、Jin Chunhuan、Kanai Yoshikatsu、Sasaki Kazuki、Minamino Naoto、Sakoda Hideyuki、Nakazato Masamitsu
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-21
- DOI
  10.1038/s41467-023-43976-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-21K11632, KAKENHI-PROJECT-22K06004, KAKENHI-PROJECT-22K06606, KAKENHI-PROJECT-22K19404, KAKENHI-PUBLICLY-22H05579, KAKENHI-PROJECT-23K24071, KAKENHI-PROJECT-23K24437
[Presentation] がん細胞におけるアミノ酸トランスポーターLAT1 の阻害はp38 MAPK 活性化を介したサイクリン D1 の下方制御により G0/G1期からS期への移行を抑制する2023
- Author(s)
  Zhou Xinyu、大垣隆一、Jin Chunhuan、Xu Minhui、岡西広樹、遠藤仁、金井好克
- Organizer
  第144回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K19451

JIN Chunhuan 金 春奐

金 春奐 ジン チュンファン

Research Projects

Research Products

アミノ酸輸送体阻害薬の標的結合構造に基づく新たな輸送体活性制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アミノ酸輸送体阻害薬の結合滞留時間／持続抑制効果の構造基盤と薬理学的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Structure activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1)2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The NERP-4-SNAT2 axis regulates pancreatic β-cell maintenance and function2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] がん細胞におけるアミノ酸トランスポーターLAT1 の阻害はp38 MAPK 活性化を介したサイクリン D1 の下方制御により G0/G1期からS期への移行を抑制する2023

Author(s)

Organizer

Data Source

JIN Chunhuan 金春奐

金春奐ジンチュンファン