TAKAHASHI Keiji 高橋敬治

… Alternative Names

高橋敬治タカハシケイジ

高橋啓治タカハシケイジ

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Researcher Number	50004685
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Affiliation (based on the past Project Information) *help	1995 – 2002: 金沢医科大学, 医学部, 教授 1997: KANAZAWA MED.SCH,DEPT OF MED., PROFESSOR, 医学部・呼吸器内科, 教授 1993: 山形大学, 医学部, 助教授 1989 – 1991: 山形大学, 医学部, 助教授 1989 – 1990: 山形大学, 医学部・臨床検査医学, 助教授 1986 – 1988: 山形大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Thoracic surgery
Keywords	Principal Investigator 肺線維症 / 肺気腫 / 肺組織傷害 / 肺組織障害 / 肺気腫化 / 肺線維化 / Elastase / Vitamin E / Bleomycin-induced lung injury / Pulmonary fibrosis … More / Pulmonary emphysema / Lung parenchymal injury / BALF細胞 / SOD / 過酸化脂質 / 血清エラスターゼ活性 / ブレオマイシン / タバコ煙 / エラスターゼ / ビタミンE / ブレオマイシン誘起性肺線維症 / Alveolar fluid clearance / Lung surfactant / Interleukin-1 beta / Inflammatory cytokines / Alveolar type II cell / Lung injury / 活性酸素 / サイトカイン受容体 / 肺線維定 / IL-1B / II型肺胞上皮細胞 / Matrix metallo proteinase / アポトーシス / NO / サイトカイン / 肺水分調節 / 肺サーファクタント / IL-1β / 炎症性サイトカイン / 肺胞II型上皮細胞 / Pulmonary Fibrosis / Pulmonary Emphysema / Lung Parenchymal Injury / Aging / Tobacco Smoke / Road Dust / Air Pollution / ブレオマイシン肺障害 / 肺の気腫化 / 肺の線維化 / ブレオマイシン肺傷害 / 肺組識弾性特性 / 加令 / 肺組識傷害 / BAL / 肺組織弾性特性 / スパイクタイヤ粉塵 / 肺サ-ファクタント / 肺組織粘弾性特性 / スパイタイヤ粉塵 / 喫煙 / 加齢 / 蛍光顕微分光 / 癌細胞識別 / 癌細胞識別装置 / 蛍光顕微分光法 / 肺癌細胞 / ポルフィリン誘導体 / 喀痰細胞診 / 自動識別 / 蛍光スペクトラム / 顕微分光 / ポリフィリン誘導体 / 細胞診 / 肺ガン … More Except Principal Investigator RT-PCR / 肺胞II型上皮細胞 / cytokine-induced neutrophil chemoattractant-1 / ventilator-induced lung injury / 肺移植 / Fas ligand / Fas / 肺サーファクタント / alveolar type II cells / rab / SURFACTANT / サーファクタント / 好中球 / 肺傷害 / レーザー分光 / pressure load / neutrophil / neutralizing antibody / broncho-alveolar lavage / CXC chemokine / CINC-1 / VILI / 圧負荷 / II型肺胞上皮細胞 / 中和抗体 / 気管支肺胞洗浄 / CXCケモカイン / ALVEOLAR TYPE II CELL / LUNG TRANSPLANTATION / 肺胞II型細胞 / oxygen radical / alveolar epithelial cell / Ischemia-reperfusion lung injury / Lung transplantation / Sodium channel / Alveolar fluid clearance / Alveolar fluid absorption / 低酸素 / β受容体 / 肺障害 / 活性酸素 / 虚血再潅流肺傷害 / ナトリウムチャンネル / β交感神経刺激薬 / 肺胞水分クリアランス / 肺胞水分再吸収 / cytokine / T lymphocyte / apoptosis / pulmonary alveolar epithelial injury / acute respiratory distress syndrome / pulmonary alveolar epithelial cell / Western blotting / western blotting / Fas Ligand / サイトカイン / Tリンパ球 / アポトーシス / 肺胞上皮損傷 / 急性呼吸窮迫症候群 / 肺胞上皮細胞 / brefeldin A / lamellar body / intracellular transport / alveolar type II cell / lung surfactant / 層状封入体 / ブレフェルジンA / 細胞内輸送 / localization / rat / Small G protein / バキュロウイルス / 分泌 / 肺 / 局在 / ラット / 低分子量Gタンパク質 / SUPEROXIDES / NEUTROPHILS / LUNG INJURY / スーパーオキサイド / Mechanical property of lung cell / Fibronectin / Lung fibroblast / 線維芽細胞の応力-歪特性 / シリコン膜 / 線維芽細胞の応力一歪特性 / 肺細胞の力学的特性 / フィブロネクチン / 肺線維芽細胞 / 光学検診法 / 蛍光スペクトル / ME / 生体工学 / 細胞診 / レーザー医療 / レーザー検診 Less

Role of CXC chemokines in pulmonary alveolar injury under mechanical stress
- Principal Investigator
  
  TOGA Hirohisa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  KANAZAWA MEDICAL UNIVERCITY
Basic Study on Preservation Conditions Of Donor's Lungs In Lung Transplantation - Development of The Standard Method for Evaluating Alveolar Type II Cells With Their Surfactant Synthetic Activities As An Indicator -
- Principal Investigator
  
  SUWABE Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  IWATE MEDICAL UNIVERSITY
  Yamagata University
Pulmonary alveolar epithelium protects the lung through apoptosis of T lymphocytes
- Principal Investigator
  
  TOGA Hirohisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa Medical University
Mechanisms in alveolar fluid absorption
- Principal Investigator
  
  SAKUMA Tsutomu
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa Medical University
Signal transduction of lung surfactant synthesis, transport, and secretion in alveolar type II cell
- Principal Investigator
  
  OSANAI Kazuhiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa Medical University
ポルフィリン誘導体を用いた微弱蛍光顕微分光法による喀痰中癌細胞識別装置の開発Principal Investigator
- Principal Investigator
  
  高橋敬治
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa Medical University
Basic Study on Lung Injuries and Neutrophils-Isolation and Purification of Alveolus-Derived Neutrophil Inhibitory Factor and Its Effects on The Development of Lung Injuries-
- Principal Investigator
  
  SUWABE Akira
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  YAMAGATA UNIVERSITY
Investigation of cell biological function of a small G protein expressed in alveolar type II cells
- Principal Investigator
  
  OSANAI Kazuhiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa Medical University
INTERACTIONS BETWEEN ALVEOLAR TYPE II CELL AND CYTOKINES IN THE LUNG INJURYPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Keiji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  KANAZAWA MEDICAL UNIVERSITY
レーザー誘起蛍光分光法による喀痰中癌細胞の自動識別装置の開発に関する研究Principal Investigator
- Principal Investigator
  
  高橋敬治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Yamagata University
Effects of Aging and Air Pollution on Development of Pulmonayr Fibrosis and Emphysema.Principal Investigator
- Principal Investigator
  
  TAKAHASHI Keiji
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University School of Medicine
Mechanism of development and progression of chronic lung injury --- An approach from mechanical property of cultured lung fibroblasts -
- Principal Investigator
  
  SATO Shinobu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University
励起癌細胞の蛍光スペクトル分析検診法の研究
- Principal Investigator
  
  丹野直弘
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Yamagata University
DEVELOPMENTAL MECHANISMS OF LUNG PARENCHYMAL INJURY EMPHYSEMA AND FIBROSI - CELL TO CELL INTERACTION IN LUNG PARENCHYMA -Principal Investigator
- Principal Investigator
  
  TAKAHASHI Keiji
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  YAMAGATA UNIVERSITY SCHOOL OF MEDICINE
励起癌細胞の螢光スペクトル分析検診法の研究
- Principal Investigator
  
  丹野直弘
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Yamagata University

All 2003 2002 2001

All Journal Article

[Journal Article] Mechanical stress on type II alveolar epithelial cells and production of CXC chemokines.2003
- Author(s)
  Toga H, Tsuchihara K, Hida M, Nakamura K, Tsuchihara C, Tobe T, Iguchi M, Ishigaki M, Nambu Y, Osanai K, Sakuma T, Takahashi K.
- Journal Title
  
  J Jpn Med Soc Biol Interface 34
  
  Pages: 77-80
- NAID
  50000000314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670621
[Journal Article] Time dependent effect of pneumonectorny on alveolar epithelial fluid clearance in rat lungs.2002
- Author(s)
  Sakuma T, Sagawa M, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Matthay M.
- Journal Title
  
  J Thorac Cardiov Surg 124
  
  Pages: 668-674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670621
[Journal Article] Effects of hypoxia on alveolar fluid transport capacity in rat lungs.2001
- Author(s)
  Sakuma T, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Inoue M, Watanabe Y.
- Journal Title
  
  J Appl Physiol 91
  
  Pages: 1766-1774
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670621
[Journal Article] Expression and localization of a novel rab small G protein (rab38) in the rat lung.2001
- Author(s)
  Osanai K, Iguchi M, Takahashi K, Nambu Y, Sakuma T, Toga H, Ohya N, Shimizu H, Fisher JH, Voelker DR.
- Journal Title
  
  Am J Pathol 158
  
  Pages: 1665-1675
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670621
[Journal Article] Inducible nitric oxide synthase expression and nuclear factor KB activation in alveolar type II cells in lung injury.2001
- Author(s)
  Toga H, Tobe T, Ueda Y, Yang G-H, Osanai K, Ishigaki M, Okazaki H, Katsuda S, Takahashi K, Ohya N.
- Journal Title
  
  Exp Lung Res 27
  
  Pages: 485-504
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670621
[Journal Article] Apoptosis of alveolar type II cells in acute respiratory distress syndrome.2001
- Author(s)
  Toga H, Kasakura H, Tobe T, Ueda Y, Yang G, Okada T, Nambu Y, Osanai K, Sakuma T, Takahashi K, Ohya N.
- Journal Title
  
  J Jpn Med Soc Biol Interface 32
  
  Pages: 24-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670621

1. SATO Shinobu (90113951)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. OSANAI Kazuhiro (70221158)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TOGA Hirohisa (90142554)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. 丹野直弘 (00006248)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. IKEDA Hideki (10175193)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SUWABE Akira (20241713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 北目文郎 (40004676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 赤塚孝雄 (80091875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAMBU Yoshihiro (20237639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UEDA Yoshimichi (50271375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAKUMA Tsutomu (90215674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISHIGAKI Masanobu (10247439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OHYA Nobuo (90064534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TANITA Tatsuo (20217144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OTAKE Kazuhisa (30312739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOBE Takeyasu (90329409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 中村秀範 (30240675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 黄正寿 (20139778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 横戸健一 (20006969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 小野貞文 (80250827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAHASHI Keiji 高橋 敬治

高橋 敬治 タカハシ ケイジ

高橋 啓治 タカハシ ケイジ

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ポルフィリン誘導体を用いた微弱蛍光顕微分光法による喀痰中癌細胞識別装置の開発Principal Investigator

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INTERACTIONS BETWEEN ALVEOLAR TYPE II CELL AND CYTOKINES IN THE LUNG INJURYPrincipal Investigator

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レーザー誘起蛍光分光法による喀痰中癌細胞の自動識別装置の開発に関する研究Principal Investigator

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Effects of Aging and Air Pollution on Development of Pulmonayr Fibrosis and Emphysema.Principal Investigator

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DEVELOPMENTAL MECHANISMS OF LUNG PARENCHYMAL INJURY EMPHYSEMA AND FIBROSI - CELL TO CELL INTERACTION IN LUNG PARENCHYMA -Principal Investigator

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TAKAHASHI Keiji 高橋敬治

高橋敬治タカハシケイジ

高橋啓治タカハシケイジ