KOKUE Eiichi 小久江栄一

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KOKUE Ei-ichi 小久江栄一

小久江栄一コクエエイイチ

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Researcher Number	50014965
Affiliation (based on the past Project Information) *help	2004: National University Corporation Tokyo University of Agriculture and Technology, Institute of Symbiotic Science and Technology, Professor, 大学院・共生科学技術研究部, 教授 1998 – 2003: 東京農工大学, 農学部, 教授 1995 – 1996: 東京農工大学, 農学部, 教授 1988 – 1989: 東京農工大学, 農学部, 助教授 1986: 農工大, 農学部, 助教授
Review Section/Research Field	Principal Investigator Basic veterinary science/Basic zootechnical science / 基礎獣医学 Except Principal Investigator 基礎獣医学 / Applied veterinary science / 動物臨床医学
Keywords	Principal Investigator reduced folate / oxidized folate / 還元型葉酸 / folacin / conceptus growth / leucovorin / folate / litter size / sow reproductive performance / 胎子重量 … More / 排卵数 / 生存胎子数 / 菌体粉末 / 合成葉酸 / 胚生存率 / 胆汁中葉酸 / 発情再帰日数 / 恒常性維持機構 / 葉酸誘導体 / 妊娠母豚 / 活性葉酸 / ロイコボリン / 産子数増加 / 血漿中葉酸濃度 / 生産子数 / 母豚繁殖効率 / ビタミン葉酸 / rats / pigs / dihydrofolate reductase / アフィニティークロマトグラフ / 二水素葉酸還元酵素 / 四水素葉酸 / 葉酸 / ビタミン / ラット / 豚 / 葉酸還元酵素 / 酸化型葉酸 / スルファモノメトキシン / スルファジメトキシン / tissue cage / ブタ … More Except Principal Investigator CYP3A / CYP1A / ニフェジピン / イヌ / drug database / drug residue / feed additive / animal drug / 医薬品データベース / 薬剤残留 / 動物用医薬品 / 医薬品デ-タベ-ス / 薬品残留 / 飼料添加物 / 動物用薬品 / dog / cimetidine / ketoconazole / erythromycin / fluoroquinolones / enzyme inhibition / ミダゾラム / ニューキノロン / CYP3A阻害 / CYP1A阻害 / キニジン / テオフィリン / オフロキサシン / シメチジン / ケトコナゾール / エリスロマイシン / フルオロキノロン / 酵素阻害 / cytochrome P450 / metabolism / acute phase response / dogs / テオフェリン / チトクロームP450 / シトクロームP450 / 薬物代謝 / 急性相反応 Less

Possible pharmacokinetic drug-drug interaction by some drugs inhibiting cytochrome P450 activities in dogs
- Principal Investigator
  
  SHIMODA Minoru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  National University Corporation Tokyo University of Agriculture and Technology
Reproductive Performance and Conceptus Development in Sows in Response to Dietary Supplementation with Oxidized and Reduced Sources of Folic AcidPrincipal Investigator
- Principal Investigator
  
  KOKUE Eiichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Tokyo University of Agriculture and Technology
Effects of Acute Phase Response on Pharmacokinetics of Drugs in Dogs
- Principal Investigator
  
  SHIMODA Minoru
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  動物臨床医学
- Research Institution
  Tokyo University of Agriculture and Technology
Low activity of dihydrofolate reductase induces poor bioavailability of folic acid in pigsPrincipal Investigator
- Principal Investigator
  
  KOKUE Eiichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY
Database System for Animal Drugs to Prevent Drug Residue
- Principal Investigator
  
  HAYAMA Toyoaki
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  基礎獣医学
- Research Institution
  Tokyo University of Agriculture and Technology
薬物の血漿アルブミンとの結合が薬物の組織分布に与える影響についてPrincipal Investigator
- Principal Investigator
  
  小久江栄一
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  基礎獣医学
- Research Institution
  Tokyo University of Agriculture and Technology

All 2002

All Journal Article

[Journal Article] Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs.2002
- Author(s)
  M.Kuroha, A.Azumano, Y.Kuze, M.Shimoda, E.Kokue
- Journal Title
  
  Drug Metab Dispos 30
  
  Pages: 63-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14560262
[Journal Article] In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic2002
- Author(s)
  M.Kuroha, Y.Kuze, M.Shimoda, E.Kokue
- Journal Title
  
  Am.J.Vet.Res 63
  
  Pages: 900-905
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14560262
[Journal Article] Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs2002
- Author(s)
  M.Kuroha, A.Azumano, Y.Kuze, M.Shimoda, E.Kokue
- Journal Title
  
  Drug Metab.Disp. 30
  
  Pages: 63-68
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14560262
[Journal Article] In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes.2002
- Author(s)
  M.Kuroha, Y.Kuze, M.Shimoda, E.Kokue
- Journal Title
  
  Am J Vet Res 63
  
  Pages: 900-905
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14560262

1. SHIMODA Minoru (50154323)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. KAMOMAE Hideo (60262226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SAITOH Toshiki (00162214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HAYAMA Toyoaki (80014893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TANIGAWA Manabu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TORIDE Yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 取手恭彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOKUE Eiichi 小久江 栄一

KOKUE Ei-ichi 小久江 栄一

小久江 栄一 コクエ エイイチ

Research Projects

Research Products

Co-Researchers

Possible pharmacokinetic drug-drug interaction by some drugs inhibiting cytochrome P450 activities in dogs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Reproductive Performance and Conceptus Development in Sows in Response to Dietary Supplementation with Oxidized and Reduced Sources of Folic AcidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of Acute Phase Response on Pharmacokinetics of Drugs in Dogs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Low activity of dihydrofolate reductase induces poor bioavailability of folic acid in pigsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Database System for Animal Drugs to Prevent Drug Residue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

薬物の血漿アルブミンとの結合が薬物の組織分布に与える影響についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs.2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes.2002

Author(s)

Journal Title

Description

Data Source

KOKUE Eiichi 小久江栄一

KOKUE Ei-ichi 小久江栄一

小久江栄一コクエエイイチ