ODA Kohei 小田耕平

Researcher Number	50081584
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: 京都工芸繊維大学, 工芸科学研究科, 教授 1992 – 2004: 京都工芸繊維大学, 繊維学部, 教授 1999: 京都工芸繊維大学, 繊維学部・応用生物学科, 教授 1987 – 1991: 大阪府立大学, 農学部, 助教授
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / Applied biochemistry / 応用微生物学・発酵学 / 発酵・醸造 Except Principal Investigator 高分子合成 / 蚕糸・昆虫利用学 / 応用微生物学・応用生物化学
Keywords	Principal Investigator カルボキシルプロテアーゼ / 構造と機能 / ペプスタチン / CLN2 / 酸性プロテアーゼ / Structure-Function Relationship / Pepstatin / アスパルティックプロテアーゼ / Aspartic proteinase / Acid proteinase … More / 触媒残基 / sedolisin / セリン-カルボキシルプロテアーゼ / structure and function / carboxyl proteinase / 立体構造 / 分子進化 / Amino acid sequence / Catalytic residue (s) / Carboxyl proteinase / Prokaryote / Pepsin type / Scytalidium type / fatal neurodegenerative disease / 致死性遺伝病 / three-dimesional structure / primary structure / subsite structure / hereditary disease / molecular evolution / 一次構造 / サブサイト構造 / 遺伝病 / 基質特異性 / 微生物 / アスパラギン酸プロテアーゼ / 細菌 / アミノ酸配列 / S-PI-insensitive / Pepstatin-insensitive / Aspartic protease / Carboxyl protease / Acid protease / ペプシンタイプ / Scytalidiumタイプ / SーPI非感受性 / ペプスタチン非感受性 / アスパルティックプロテア-ゼ / カルボキシルプロテア-ゼ / 酸性プロテア-ゼ / Glutamic protease / S-PI非感受性 / アスパルテックプロテアーゼ / グルタミックプロテア-ゼ / proteinase inhibitor / reaction mechanism / substrate specificity / serine-carboxvl proteinase / elutamic nentidase / e olisin / グルタミン酸プロテアーゼ / ペプチダーゼ / プロテアーゼ / serine-carboxy1 peptidase / プロテアーゼインヒビター / 反応メカニズム / serine-carboxyl peptidase / glutamic peptidase / eqolisin / novel peptidase family / serine-carboxyl pepetidases / セドリシン / 新プロテアーゼファミリー / inhibitor / serine-carboxyl proteinase / three-dimensional structure / catalytic mechanism / pepstatin / Batten disease / セリンカルボシルプロテアーゼ / バッテン症 / インヒビター / セリンカルボキシルプロテアーゼ / 触媒機構 / バッテン病 / クローニング / NCL病 / 分子進行 / 酵性プロテアーゼ / ペプスタン / カルボキシプロテアーゼ / 原核生物 / Pepstain-insensitive / Carboxyl proteinases / 塩基配列 / プレプロ体 … More Except Principal Investigator bio-degradation / polyester / PET-decomposing microorganism / plastic / terephthalate / polyethylene terephthalate / 生分解 / バイオリアクター / 細菌 / 分解酵素 / 分解機構 / 酵母 / 微生物分解 / ポリエステル / PET分解菌 / プラスチック / テレフタル酸 / ポリエチレンテレフタレート / Programd Cell Death / Nuclease / Protease / Apoptosis / Midgut / Silkworm / RNA結合蛋白質 / 二本鎖RNA分解酵素 / プログラム細胞死 / ヌクレアーゼ / プロテアーゼ / アポトーシス / カイコ消化管 / structure / proteinaceous / metalloproteinase / inhibitor / mutant / killer toxin / Streptomyces / metallo proteinase / Inhibitor Less

Discovery of two novelproteinases andtheirbi rl emical resemphPrincipal Investigator
- Principal Investigator
  
  HIRAGA Kazumi, 小田耕平
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto Institute of Technology
Biochemical characterization of human CLN2, related to a fatal neurodegenerative disease : On the basis of the discovery of a novel family of peptidasesPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto Institute of Technology
Microbial carboxyl proteinases related to a fatal neurodegenerative disease: proposal for a novel catalytic mechanismPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO INSTITUTE OF TECHNOLOGY
Development of a novel biotechnology for decomposing of plastic using PET (polyethylene terephthalate)-decomposing microorganisms
- Principal Investigator
  
  KIMURA Yoshiharu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  高分子合成
- Research Institution
  Kyoto Institute of Technology
Structure-Function, and Molecular Evolution of NCL disease-related Novel Carboxyl Proteinases from BacteriaPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Institute of Technology
Novel Carboxyl Proteinases : Structure, Function, and EvolutionPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Institute of Technology
蛋白性メタルプロテアーゼインヒビター,SMPIの構造・機能解析と応用
- Principal Investigator
  
  HIRAGA Kazumi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Institute of Technology
Structure-Function Relationships and Molecular Evolutions of Novel Carboxyl Proteinases from MicroorganismsPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Faculty of Textile Science, Kyoto Institute of Technology
Structure-Function of Novel Carboxyl Proteinases from MicroorganismsPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Faculty of Textile Science, Kyoto Institute of Technology
Function of 27K nuclease in relation to apoptosis in the digestive organ of the silkworm, Bombyx mori.
- Principal Investigator
  
  FURUSAWA Toshiharu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  蚕糸・昆虫利用学
- Research Institution
  Kyoto Institute of Technology
Structure-Function Relationships of Pepstatin-insensitive Carboxyl Proteinases from ProkaryotesPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Institute of Technology
Structure-Function Relationships of Pepstation-insensitive Carboxyl Proteinase from BacteriaPrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  Faculty of Textile Science. Kyoto Institute of Technology
Structure-Function Relationships of Pepstatin-insensitive Caroboxyl Protease produced by Pseudomonas sp. No. 101Principal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  College of Agriculture, University of Osaka Prefecture
Pepstatin-Insensitive Carboxyl Proteinase : Glutamic ProteinasePrincipal Investigator
- Principal Investigator
  
  ODA Kohei
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  発酵・醸造
- Research Institution
  University of Osaka Prefecture

All 2007 2006 2004 2003

All Journal Article

[Journal Article] Crystal structure of Scytalidoglutamic peptidase with its first potent inhibitor provides insights into substrate specificity and catalysis2007
- Author(s)
  B., Fillai, M. M., Cherney, K., Hiraga, K., Takada, K., Oda, M. N., G., James
- Journal Title
  
  T. Mal Biol 365
  
  Pages: 343-361
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18380068
[Journal Article] Processing, catalytic activity and crystal structures of kumolisin-As with an engineered active site2006
- Author(s)
  A., Okubo, Mi, Li, M., Ashida, H., Oyama, A., Gustchina, K., Oda, B. M., Dunn, A., Wlodawer, T., Nakayama
- Journal Title
  
  FEBS-Journal 273
  
  Pages: 2563-2576
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18380068
[Journal Article] Synergetic effects of pressure and chemical denaturant on protein unfolding : stability of a serine-type carboxyl protease, kumamolisin2006
- Author(s)
  Y., Fujimoto, H., Ikeuchi, T., Tada, H., Oyama, K., Oda, S., Kunugi
- Journal Title
  
  Biochim. Biophys. Acta 1764
  
  Pages: 364-371
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18380068
[Journal Article] Two inhibitor molecules bound in the active site of Pseudomonas sedolisin : a model for the bi-product complex following cleavage of a peptide substrate.2004
- Author(s)
  Wlodawer A
- Journal Title
  
  Biochem.Biophys.Res.Commun. 314
  
  Pages: 638-645
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity.2004
- Author(s)
  Wlodawer A
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 21500-21510
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity.2004
- Author(s)
  Wlodawer A., et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 21500-21510
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] 新規プロテアーゼファミリー、セドリシンの発見2004
- Author(s)
  小田耕平
- Journal Title
  
  化学と工業 78
  
  Pages: 174-181
- NAID
  40006158512
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] Two inhibitor molecules bound in the active site of Pseudomonas sedolisin : a model for the biproduct complex following cleavage of a peptide substrate.2004
- Author(s)
  Wlodawer A., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 314
  
  Pages: 638-645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] A novel family of proteinases, sedolisin. (in Japanese)2004
- Author(s)
  Oda, K.
- Journal Title
  
  Kagaku to Kogyo 78
  
  Pages: 174-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] 新規プロテアーゼファミリー・sedolisinの構造と機能2003
- Author(s)
  小田耕平
- Journal Title
  
  バイオサイエンスとバイオインダストリー 61
  
  Pages: 11-16
- NAID
  10011624165
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] Structural and enzymatic properties of the sedolisin family of serine-carboxyl peptidases.2003
- Author(s)
  Wlodawer A
- Journal Title
  
  Acta Biochim Pol. 50
  
  Pages: 81-102
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] A model of tripeptidyl-peptidase I (CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases.2003
- Author(s)
  Wlodawer A
- Journal Title
  
  BMC Struct.Biol. 3
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] Structural and enzymatic properties of the sedolisin family of serine-carboxyl peptidases.2003
- Author(s)
  Wlodawer A., et al.
- Journal Title
  
  Acta Biochemica Polonica 50
  
  Pages: 81-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] A model of tripeptidyl-peptidase I (CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases.2003
- Author(s)
  Wlodawer A., et al.
- Journal Title
  
  BMC Struct.Biol. 3(1)
  
  Pages: 8-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380072
[Journal Article] Structures and functions of a novel proteinase family, sedolisin. (in Japanese)2003
- Author(s)
  Oda, K., et al.
- Journal Title
  
  Bioscience and Bioindustry 61
  
  Pages: 11-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380072

1. HIRAGA Kazumi (50252549)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. OYAMA Hiroshi (50221700)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. FURUSAWA Toshiharu (70127166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KOTANI Eiji (10273541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MORI Hajime (80201812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUGIMURA Yukiko (20273542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KIMURA Yoshiharu (10132276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIYAMOTO Masatoshi (70149524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋砂織 (10142184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAY John

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. DUNN Ben M

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. DUNN B.M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAY Jhon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. DUNN Ben M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ODA Kohei 小田 耕平

Research Projects

Research Products

Co-Researchers

Discovery of two novelproteinases andtheirbi rl emical resemphPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biochemical characterization of human CLN2, related to a fatal neurodegenerative disease : On the basis of the discovery of a novel family of peptidasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Microbial carboxyl proteinases related to a fatal neurodegenerative disease: proposal for a novel catalytic mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel biotechnology for decomposing of plastic using PET (polyethylene terephthalate)-decomposing microorganisms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure-Function, and Molecular Evolution of NCL disease-related Novel Carboxyl Proteinases from BacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel Carboxyl Proteinases : Structure, Function, and EvolutionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

蛋白性メタルプロテアーゼインヒビター,SMPIの構造・機能解析と応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure-Function Relationships and Molecular Evolutions of Novel Carboxyl Proteinases from MicroorganismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure-Function of Novel Carboxyl Proteinases from MicroorganismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of 27K nuclease in relation to apoptosis in the digestive organ of the silkworm, Bombyx mori.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure-Function Relationships of Pepstatin-insensitive Carboxyl Proteinases from ProkaryotesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure-Function Relationships of Pepstation-insensitive Carboxyl Proteinase from BacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure-Function Relationships of Pepstatin-insensitive Caroboxyl Protease produced by Pseudomonas sp. No. 101Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

ODA Kohei 小田耕平