FUKUDA Mamoru 福田護

Researcher Number	50081724
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004 – 2007: 聖マリアンナ医科大学, 医学部, 教授 2002: 聖マリアンナ医科大学, 医学部, 教授 1997 – 2002: 聖マリアンナ医科大学, 医学部, 助教授 1994: St.Marianna University, 1st Department of Surgery, Associate Professor, 医学部, 助教授
Review Section/Research Field	Principal Investigator General surgery / General surgery Except Principal Investigator General surgery
Keywords	Principal Investigator BARD1 / BRCA1 / p53 / ubiquitin ligase / ユビキチンリガーゼ / 2D-DIGE / HERC2 / familial breast cancer / Cyclin E / SPIN … More / RPB8 / 家族性乳癌 / scFv / RINGフィンガー / CDK2ΔT / T-loop / variant / breast cancer / 細胞周期 / western blotting / c-erbB-2 / p34^<cdc2> / 乳癌 / proteomics / プロテオミクス / Nucleophosmin / RING finger / protein degradation / gene therapy / ScFv / タンパク質分解 / 遺伝子治療 / CDC2ΔT / cell cycle / RT-PCR / Δcdk2 / Δcdc2 / p21 / cdk2 / cdc2 / CDK2 / CDC2 / mammography / immunostaining / non-palpable breast cancer / カテプシンD / c-erbB / P34^<cdc2> / マンモグラフィ / 免疫染色 / 非触知 … More Except Principal Investigator BARD1 / BRCA1 / Ligase / ubiquitin / RING finger / breast cancer / ヘテロダイマー / RINGフィンガー / タンパク質分解 / ユビキチンリガーゼ / 家族性乳癌 Less

Identification of novel breast cancer-related genes using 2D-DIGE system and their functional analysesPrincipal Investigator
- Principal Investigator
  
  FUKUDA Mamoru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
Roles of BRCA1 in sporadic breast cancerPrincipal Investigator
- Principal Investigator
  
  FUKUDA Mamoru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
Selective degradation of p53 mutant by an engineered ScFv-linked ubiquitin ligasePrincipal Investigator
- Principal Investigator
  
  FUKUDA Mamoru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Elucidation of substrates and analysis of the function of BRCA 1 ubiquitin ligase
- Principal Investigator
  
  TOMOHIKO Ohta
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Molecular Cloning and Functional Analysis of CDK Variant Expressed in Breast Cancer TissuesPrincipal Investigator
- Principal Investigator
  
  FUKUDA Mamoru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
Proliferative activities of non-palpable breast cancer detected by mammographyPrincipal Investigator
- Principal Investigator
  
  FUKUDA Mamoru, 福田護
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University

All 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] よくわかる乳癌治療2007
- Author(s)
  福田護
- Total Pages
  159
- Publisher
  主婦と生活社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591445
[Book] よくわかる乳がん治療2007
- Author(s)
  福田護
- Total Pages
  159
- Publisher
  主婦と生活社
- Data Source
  KAKENHI-PROJECT-18591445
[Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008
- Author(s)
  Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T.
- Journal Title
  
  Cancer Sci. 99(1)
  
  Pages: 62-70
- NAID
  10024000927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591445
[Journal Article] Elevated expression of PRC1, involved in the growth of breast cancer cells.2007
- Author(s)
  Shimo A, Nishidate T, Ohta T, Fukuda M, Nakamura Y, Katagiri T.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 174-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591445
[Journal Article] Functional Mapping of BRCA1/BARD1 Domain Required for Ubiquitination of NPM1.2007
- Author(s)
  Honda A, Ohta T, Fukuda M.
- Journal Title
  
  The St. Marianna Journal 35(5)
  
  Pages: 255-267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591445
[Journal Article] BRCA1 ubiquitinates RPB8 in response to DNA damage.2007
- Author(s)
  Wu W, Nishikawa H, Hayami R, Sato K, Honda A, Aratani S, Nakajima T, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Res. 67(3)
  
  Pages: 951-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591445
[Journal Article] A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats.2006
- Author(s)
  Tsuzuki M, Wu W, Nishikawa H, Hayami R, Oyake D, Yabuki Y, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Lett. 233(1)
  
  Pages: 108-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591279
[Journal Article] Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.2005
- Author(s)
  Hayami R, Sato K, Wu W, Nishikawa T, Hiroi J, Ohtani-Kaneko R, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Res. 65(1)
  
  Pages: 6-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591279
[Journal Article] Breast tumor suppressor BRCA12004
- Author(s)
  Ohta T, Hayami R, Wu W, Fukuda M.
- Journal Title
  
  New Horizon Med. (Japanese) 36(4)
  
  Pages: 167-173
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591279
[Journal Article] BRCA1 ubiquitin ligase and breast cancer2004
- Author(s)
  Ohta T, Fukuda M.
- Journal Title
  
  J. Clin Exp.Med. (Japanese) 211(1)
  
  Pages: 49-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591279
[Journal Article] Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase.2004
- Author(s)
  Sato K, Hayami R, Wu W, Nishikawa T, Nishikawa H, Okuda Y, Ogata H, Fukuda M, Ohta T.
- Journal Title
  
  J.Biol.Chem. 279(30)
  
  Pages: 30919-30922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591279
[Presentation] Molecular functions of BRCA1 E3 ubiquitin ligase in cell cycle and DNA damage response2007
- Author(s)
  Ohta T., Wu W., Fukuda M.
- Organizer
  The 66th annual meeting of the Japanese cancer association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591445
[Presentation] Ubiquitin ligase activity of BRCA1, a hub protein that regulates multiple cellular pathways2006
- Author(s)
  Ohta T., Wu W., Fukuda M.
- Organizer
  MBSJ forum 2006 of the molecular biology society of Japan
- Place of Presentation
  Nagoya
- Year and Date
  2006-12-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591445

1. OHTA Tomohiko (60233136)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. OGATA Haruki (60267581)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 福田護 (70059442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TADOKORO Mamoru (80081644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKAKUWA Toshifumi (90121201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ARIMURA Toshihiro (70232072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 渡部省二 (30113020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUKUDA Mamoru 福田 護

Research Projects

Research Products

Co-Researchers

Identification of novel breast cancer-related genes using 2D-DIGE system and their functional analysesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of BRCA1 in sporadic breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Selective degradation of p53 mutant by an engineered ScFv-linked ubiquitin ligasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of substrates and analysis of the function of BRCA 1 ubiquitin ligase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Cloning and Functional Analysis of CDK Variant Expressed in Breast Cancer TissuesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proliferative activities of non-palpable breast cancer detected by mammographyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] よくわかる乳癌治療2007

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] よくわかる乳がん治療2007

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.2008

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Elevated expression of PRC1, involved in the growth of breast cancer cells.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Functional Mapping of BRCA1/BARD1 Domain Required for Ubiquitination of NPM1.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] BRCA1 ubiquitinates RPB8 in response to DNA damage.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.2005

Author(s)

Journal Title

FUKUDA Mamoru 福田護