TAMOTO Koichi 田元浩一

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TAMOTO Kouichi 田元浩一

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Researcher Number	50088861
Other IDs
Affiliation (based on the past Project Information) *help	2012: 徳島文理大学, 薬学部, 教授 2010 – 2012: 徳島文理大学, 香川薬学部, 教授 2003 – 2005: 北海道医療大学, 薬学部, 助教授 1996 – 1998: HEALTH SCIENCES UNIVERSITY OF HOKKAIDO,FACULTY OF PHARMACEUTICAL SCIENCE,ASSOC.P, 薬学部, 助教授 1987: Higashi-Nippon-Gakuen university, Faculty of Pharmaceutical Scienes, Assistant Professor, 薬学部, 助教授 1986: 東日本学園大, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy Except Principal Investigator Drug development chemistry / Functional biochemistry / Applied veterinary science
Keywords	Principal Investigator NADPH-cytochrome c reductase / 滑膜細胞 / protein phosphorylation / macrophages / flavoprotein / O_2^--generating enzyme / 抗NADPH-チトクロムP450 reductase抗体 / スーパーオキサイドアニオン生成酵素 / 蛋白質リン酸化 / 多形核白血球 … More / マクロファ-ジ / フラビン蛋白質 / O3^2_生成酵素 / monoclonal antibody / prostaglandine E2 / cyclooxygenase 2 / hyaluronan receptor / fibroblast / synovial cells / rheumatoid arthritis / hyaluronan / プロスタグランジンE2 / ヒアルロン酸レセプター / モノクローナル抗体 / プロスタグランジンE_2 / シクロオキシゲナーゼ2 / ヒアルロン酸受容体 / 線維芽細胞 / 慢性関節リウマチ / ヒアルロン酸 / リゾボスファチジン酸 / シクロオキシゲナーゼ２ / LPA受容体 / LPA 受容体 / リゾホスファチジン酸 / リゾリン脂質 / 関節リウマチ … More Except Principal Investigator TNF-α / CD18 / BLAD / IкBα / MAP kinase / NFкB / Signaling pathway / anti-inflammatory action / Cyclooxygenase-2 / Ozonide / 抗炎症薬 / IκBα / MAPキナーゼ / NFκB / シグナル伝達系 / 抗炎症作用 / シクロオキシゲナーゼ-2 / オゾニド / proton-sensing receptor / vascular smooth muscle cell / vascular endothelial cell / lipoprotein / G-protein-coupled receptor / lipid mediator / lysophosphatidic acid / sphingosine 1-phosphate / 膵臓がん / LPA受容体アンタゴニスト / 細胞遊走 / アストロサイト / オートタキシン / 神経突起退縮 / TDAG8 / 動脈硬化 / 高密度リポ蛋白 / OGR1 / サイコシン / プロトン感知性受容体 / 血管平滑筋細胞 / 血管内皮細胞 / リポ蛋白質 / G蛋白共役型受容体 / 脂質性シグナル分子 / リゾホスファチジン酸 / スフィンゴシン1-リン酸 / disease control / BLAD-carrier / leukocyte functions / bovine immunodeficiency / BLAD-キャリャ- / Fcリセプター / 免疫組織検索 / 遺伝子頻度 / キャリャ-率 / DNA-PCR / 好中球機能 / 遺伝疾患 / BLAD-キャリヤ- / 白血球機能 / ウシ免疫不全 / 接着分子CD18 Less

Roles of intracellular signaling through lysophospholipid receptors in synovial cells in rheumatoid arthritis pathogenesis.Principal Investigator
- Principal Investigator
  
  TAMOTO Koichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokushima Bunri University
Supression of the expression of cyclooxygenase-2 by ozonides of oleate ester
- Principal Investigator
  
  MIURA Toshiaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
Regulation of distribution of extracellular Edg receptor family ligands and their physiological roles
- Principal Investigator
  
  OKAJIMA Fumikazu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Gunma University
STUDIES ON THE MECHANISM OF SIGNAL TRANSDUCTION THROUGH HYALURONAN RECEPTORS IN HUMAN SYNOVIAL CELLS OF RHEUMATOID ARTHRITIS.Principal Investigator
- Principal Investigator
  
  TAMOTO Koichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
Characterization of leukocyte functions from cattle with leukocyte adhesion deficiency (BLAD) and prevalence of BLAD-carrier in Holstein cattle in Japan
- Principal Investigator
  
  NAGAHATA Hajime
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  RAKUNO GAKUEN UNIVERSITY,FACULTY OF VETERINARY MEDICINE
Analysis of structure and function of flavin enzyme in o_<> ^--generating enzyme of quinea pig phagocytes.Principal Investigator
- Principal Investigator
  
  TAMOTO Koichi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HIGASHI-NIPPON-GAKUEN-UNIVERSITY

All 2013 2012 2011 2010 2005 2004 2003

All Journal Article Presentation

[Journal Article] Sphingosine-1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation Through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Coronary Artery Smooth Muscle Cells.2005
- Author(s)
  Damirin A, Tomura H, Komachi M, Tobo M, Sato K, Mogi C, Nochi H, Tamoto K, Okajima F.
- Journal Title
  
  Mol. Pharmacol 67
  
  Pages: 1177-1185
- Data Source
  KAKENHI-PROJECT-15370051
[Journal Article] Identification of Autotaxin as a Neurite Retraction-Inducing Factor of PC12 Cells in Cerebrospinal Fluid and Its Possible Sources.2005
- Author(s)
  Sato K, Malchinkhuu E, Muraki T, Ishikawa K, Hayashi K, Tosaka M, Mochiduki A, Inoue K, Tomura H, Mogi C, Nochi H, Tamoto K, Okajima F
- Journal Title
  
  J.Neurochem. 92
  
  Pages: 904-914
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370051
[Journal Article] Sphingosine-1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation Through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Coronary Artery Smooth Muscle Cells.2005
- Author(s)
  Damirin A, Tomura H, Komachi M, Tobo M, Sato K, Mogi C, Nochi H, Tamoto K, Okajima F
- Journal Title
  
  Mol.Pharmacol. 67
  
  Pages: 1177-1185
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370051
[Journal Article] Identification of Autotaxin as a Neurite Retraction-Inducing Factor of PC12 Cells in Cerebrospinal Fluid and Its Possible Sources.2005
- Author(s)
  Koichi Sato, Enkhzol Malchinkhuu, Takeshi Muraki, Koichi Ishikawa, Kensuke Hayashi, Masahiko Tosaka, Akikazu Mochiduki, Kinji Inoue, Hideaki Tomura, Chihiro Mogi, Hiromi Nochi, Koichi Tamoto, Fumikazu Okajima
- Journal Title
  
  J.Neurochem. (印刷中)
- Data Source
  KAKENHI-PROJECT-15370051
[Journal Article] Lysophosphatidic Acid in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells Through LPA_1.2004
- Author(s)
  Yamada T, Sato K, Komachi M, Malchinkhuu E, Tobo M, Kimura T, Kuwabara A, Yanagita Y, Ikeya T, Tanahashi Y, Ogawa T, Ohwada S, Morishita Y, Ohta H, Im DS, Tamoto K, Tomura H, Okajima F
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 6595-6605
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370051
[Journal Article] Lysophosphatidic Acid in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells Through LPA_12004
- Author(s)
  Yamada T, Sato K, Komachi M, Malchinkhuu E, Tobo M, Kimura T, Kuwabara A, Yanagita Y, Ikeya T, Tanahashi Y, Ogawa T, Ohwada S, Morishita Y, Ohta H, ImDS, Tamoto K, Tomura H, Okajima F.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 6595-6605
- Data Source
  KAKENHI-PROJECT-15370051
[Journal Article] Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors.2003
- Author(s)
  Ohta H, Sato K, Murata N, Damirin A, Malchinkhuu E, Kon J, Kimura T, Tobo M, Yamazaki Y, Watanabe T, Yagi M, Sato M, Suzuki R, Murooka H, Sakai T, Nishitoba T, Im DS, Nochi H, Tamoto K, Tomura H, Okajima F
- Journal Title
  
  Mol Pharmacol. 64
  
  Pages: 994-1005
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370051
[Presentation] 細胞外環境の酸性化は関節リウマチ滑膜細胞のLPA受容体を介した炎症応答を増大させる2013
- Author(s)
  野地裕美、徳永絢香、原香織、田中信行、戸村秀明、岡島史和、田元浩一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590096
[Presentation] 細胞外環境の酸性化は関節リウマチ滑膜細胞のLPA受容体を介した炎症応答を増大させる2013
- Author(s)
  野地裕美、徳永絢香、原香織、田中信行、戸村秀明、岡島史和、（田元浩一）
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590096
[Presentation] 細胞外環境の酸性化が関節リウマチ滑膜細胞の炎症応答に及ぼす影響2012
- Author(s)
  野地裕美、中川尭亮、石原悠衣、田中信行、戸村秀明、岡島史和、田元浩一
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590096
[Presentation] 細胞外環境の酸性化が関節リウマチ滑膜細胞の炎症応答に及ぼす影響2012
- Author(s)
  野地裕美、中川尭亨、石原悠衣、田中信行、戸村秀明、岡島史和、田元浩一
- Organizer
  日本薬学会大32年会
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22590096
[Presentation] 細胞外環境の酸性化が関節リウマチ滑膜細胞のCOX-2発現に及ぼす影響2011
- Author(s)
  野地裕美、中川尭亨、田中信行、戸村秀明、岡島史和、田元浩一
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22590096
[Presentation] 細胞外環境の酸性化が関節リウマチ滑膜細細胞のCOX-2発現に及ぼす影響2011
- Author(s)
  野地裕美、中川尭亮、戸村秀明、岡島史和、田元浩一
- Organizer
  第84回生化学会
- Place of Presentation
  京都.
- Data Source
  KAKENHI-PROJECT-22590096
[Presentation] ヒアルロン酸による炎症応答の調節2010
- Author(s)
  田元浩一、野地裕美、田中信行、岡島史和
- Organizer
  セルロース学会第17回年次大会
- Place of Presentation
  さぬき
- Data Source
  KAKENHI-PROJECT-22590096

1. NOCHI Hiromi (30183552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. NAGAHATA Hajime (10133571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TANIYAMA Hiroyuki (90133800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OKAJIMA Fumikazu (30142748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. TOMURA Hideaki (70217553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. SATO Koichi (00302498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. MIURA Toshiaki (10091505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUDA Tadashi (20212219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAZUNOBU Miura (70001980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. GARY J. Koci

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOCIBA Gary J

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GARY J Kocib

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAMOTO Koichi 田元 浩一

TAMOTO Kouichi 田元 浩一

Research Projects

Research Products

Co-Researchers

Roles of intracellular signaling through lysophospholipid receptors in synovial cells in rheumatoid arthritis pathogenesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Supression of the expression of cyclooxygenase-2 by ozonides of oleate ester

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of distribution of extracellular Edg receptor family ligands and their physiological roles

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDIES ON THE MECHANISM OF SIGNAL TRANSDUCTION THROUGH HYALURONAN RECEPTORS IN HUMAN SYNOVIAL CELLS OF RHEUMATOID ARTHRITIS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of leukocyte functions from cattle with leukocyte adhesion deficiency (BLAD) and prevalence of BLAD-carrier in Holstein cattle in Japan

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of structure and function of flavin enzyme in o_<> ^--generating enzyme of quinea pig phagocytes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sphingosine-1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation Through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Coronary Artery Smooth Muscle Cells.2005

Author(s)

Journal Title

Data Source

[Journal Article] Identification of Autotaxin as a Neurite Retraction-Inducing Factor of PC12 Cells in Cerebrospinal Fluid and Its Possible Sources.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Sphingosine-1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation Through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Coronary Artery Smooth Muscle Cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Identification of Autotaxin as a Neurite Retraction-Inducing Factor of PC12 Cells in Cerebrospinal Fluid and Its Possible Sources.2005

Author(s)

Journal Title

Data Source

[Journal Article] Lysophosphatidic Acid in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells Through LPA_1.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Lysophosphatidic Acid in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells Through LPA_12004

Author(s)

Journal Title

Data Source

[Journal Article] Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors.2003

Author(s)

Journal Title

Description

Data Source

[Presentation] 細胞外環境の酸性化は関節リウマチ滑膜細胞のLPA受容体を介した炎症応答を増大させる2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 細胞外環境の酸性化は関節リウマチ滑膜細胞のLPA受容体を介した炎症応答を増大させる2013

Author(s)

TAMOTO Koichi 田元浩一

TAMOTO Kouichi 田元浩一