uesato shinnichi 上里新一

… Alternative Names

Researcher Number	50111969
Other IDs
Affiliation (Current)	2019: 大阪薬科大学, 薬学部, 研究員
Affiliation (based on the past Project Information) *help	2015: 関西大学, 工学部, 教授 2012: 関西大学, 工学部, 教授 2007 – 2011: Kansai University, 化学生命工学部, 教授 2003 – 2005: 関西大学, 工学部, 教授 2002: 関西大, 工学部, 教授 1986 – 1987: 京都大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Synthetic chemistry / Synthetic chemistry / Living organism molecular science Except Principal Investigator Drug development chemistry / Chemical pharmacy / Clinical oncology / Neurology
Keywords	Principal Investigator 抗タキソールモノクローナル抗体 / タキソール / モノクローナル抗体 / P388 / p21 / WAF1 / neu / SKBR3 / Herceptin / 抗ビンブラスチンモノクローナル抗体 … More Except Principal Investigator HDAC / HDAC阻害剤 / 非ウイルスベクター / ヒストン脱アセチル化酵素阻害剤 / 遺伝子発現 / ヒストン脱アセチル化酵素 / ナノ粒子 / 遺伝子ベクター / ナノパーティクル / リポソーム / 抗がん剤 / DDS / プロドラッグ / ドラッグデリバリーシステム / DNAナノプレックス / 遺伝子発現増強 / ナノプレックス / リポフェクション / 遺伝子導入 / 細胞がん化 / がん化学療法 / ERK-MAP キナーゼ経路 / MEK 阻害剤 / 微小管重合阻害剤 / HDAC 阻害剤 / 併用療法 / Bcl-2 ファミリー蛋白質 / ERK-MAPキナーゼ経路 / MEK阻害剤 / 微小管阻害剤 / 動物個体系 / セコイリドイド配糖体 / モクセイ科 / 生合成 / 標識物質の合成 / アマロゲンチン / ビフェニル / 木材腐朽菌 / アミノイソ酪酸 / アミノアルコール / ヒペルシン / トリコポリン / トリコスポリン / ヒポクレア / トリコデルマ / レンチアレキシン / wood-rotting fungi / aminoisobutyric acid / aminoalcohol / hypelcin / trichopolyn / trichosporin / Hypocrea / Trichoderma / 脳虚血 / シグナルトランスダクション / ＣＲＥＢ / ＳＩＫ（塩誘導性キナーゼ） / ＨＤＡＣ（ヒストン脱アセチル化酵素） / パーキンソン病 / ＨＤＡＣ阻害剤 / 創薬 / CRTC / SIK（塩誘導性キナーゼ） / アポトーシス / CREB / エピゲノム / TORC / 低分子化合物 / 神経疾患 / 脳卒中 Less

The role and mechanisms of TORC and HDAC signaling pathway and therapeutic new-class small compounds for neurological disease
- Principal Investigator
  
  sasaki tsutomu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Osaka University
Targeting the ERK-MAP kinase pathway in cancer therapy
- Principal Investigator
  
  KOHNO Michiaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Kyoto University
  Nagasaki University
Development of cationic histone deacetylase inhibitors as enhancer of gene transfection and expression
- Principal Investigator
  
  NAGAOKA Yasuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kansai University
Attempted synthesis of taxol utilizing anti-taxol monoclonal antibody as a as a chiral mouldPrincipal Investigator
- Principal Investigator
  
  UESATO Shinichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Kansai University
Synthesis of Histone Deacetylase Inhibitors Toward the Development of DDS
- Principal Investigator
  
  NAGAOKA Yasuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kansai University
Design of the anti-tumor agents targeting the functional proteins involved in cancer cell growthPrincipal Investigator
- Principal Investigator
  
  UESATO Shinichi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kansai University
モノクローナル抗体を反応場として用いた天然抗がん剤の新規合成法の開発Principal Investigator
- Principal Investigator
  
  上里新一
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Synthetic chemistry
- Research Institution
  Kansai University
セコイリドイド配糖体の生合成研究
- Principal Investigator
  
  INOUE KENICHIRO
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Drug development for antimicrobial and immunodepressive substrances produced by wood-rotting fungi
- Principal Investigator
  
  FUJITA TETSURO
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
  The University of Tokushima

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2004 2003 Other

All Journal Article Presentation

[Journal Article] Discovery of new low-molecular-weight p53-Mdmx disruptors and their anti-cancer activities.2016
- Author(s)
  Uesato, S.; Matsuura, Y.; Matsue, S.; Sumiyoshi, T.; Hirata, Y.; Takemoto, S.; Kawaratani, Y.; Yamai, Y.; Ishida, K.; Sasaki, T.; Enari, M.
- Journal Title
  
  Bioorg Med Chem.
  
  Volume: 24 Pages: 1919-1926
- DOI
  10.1016/j.bmc.2016.03.021
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18903, KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-16K15317
[Journal Article] A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease.2016
- Author(s)
  Choong CJ, Sasaki T, Hayakawa H, Yasuda T, Baba K, Hirata Y, Uesato S, Mochizuki H.
- Journal Title
  
  Neurobiol Aging.
  
  Volume: 37 Pages: 103-116
- DOI
  10.1016/j.neurobiolaging.2015.10.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01558, KAKENHI-PROJECT-24390222
[Journal Article] Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models2013
- Author(s)
  Sakamoto, T., Ozaki, K., Fujio, K., Kajikawa, S., Uesato, S., Watanabe, K., Tanimura, S., Koji, T. & Kohno, M
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 433 Pages: 456-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300340
[Journal Article] Anti-tumor activity of new orally bioavailable 2-amino-5-(thiophen-2-yl) benzamide-series histone deacetylase inhibitors, possessing an aqueous soluble functional group as a surface recognition domain2012
- Author(s)
  Y. Hirata, M. Hirata, Y. Kawaratani, M. Shibano, M. Taniguchi, M. Yasuda, Y. Ohmomo, Y. Nagaoka, K. Baba, S. Uesato
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 22(5) Pages: 1926-1930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590131
[Journal Article] Antitumor effect of liposomal histone deacetylase inhibitor-lipid conjugates in vitro2011
- Author(s)
  Y. Hattori, Y. Nagaoka, M. Kubo, H. Yamasaku, Y. Ishii, S. Uesato, Y. Maitani
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume: 59(11) Pages: 1386-1392
- NAID
  130001274814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590131
[Journal Article] New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl group. Bioorg2011
- Author(s)
  Y.Kawaratani, T.Harada, Y.Hirata, Y.Nagaoka, S.Uesato, 他5名
- Journal Title
  
  Med. Chem
  
  Volume: 19 Pages: 3995-4003
- DOI
  10.1016/j.bmc.2011.05.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590131, KAKENHI-PROJECT-23790090
[Journal Article] Antitumor Effect of Liposomal Histone Deacetylase Inhibitor-Lipid Conjugates in Vitro2011
- Author(s)
  Y.Hattori, Y.Nagaoka, Shinichi Uesato, 他4名
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 59 Issue: 11 Pages: 1386-1392
- DOI
  10.1248/cpb.59.1386
- NAID
  130001274814
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590131, KAKENHI-PROJECT-23790203
[Journal Article] New microtubule polymerization inhibitors comprising a nitrooxymethyl phenyl group.2011
- Author(s)
  Kawaratani Y., Harada T., Hirata Y., Nagaoka Y., Tanimura S., Shibano M., Taniguchi M., Yasuda M., Baba K. & Uesato S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 19 Pages: 3995-4003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300340
[Journal Article] Therapeutic Effect of Arctiin and Arctigenin in Immunocompetent and Immunocompromised Mice Infected with Influenza A Virus2010
- Author(s)
  K.Hayashi, K.Narutaki, Y.Nagaoka, T.Hayashi, S.Uesato
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 33 Pages: 1199-1205
- NAID
  130000300287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590131
[Journal Article] Histone Deacetylase Inhibitor Prodrugs in Nanoparticle Vector Enhanced Gene Expression in Human Cancer Cells Euro2009
- Author(s)
  Y. Ishii, Y. Hattori, T. Yamada, S. Uesato, Y. Maitani, Y. Nagaoka
- Journal Title
  
  J. Med. Chem
  
  Volume: 44(11) Pages: 4603-4610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590131
[Journal Article] Histone deacetylase inhibitor prodrugs in nanoparticle vector enhancedgene expression in human cancer cells.2009
- Author(s)
  Ishii Y., Hattori Y., Yamada T., Uesato S, Maitani K., Nagaoka Y
- Journal Title
  
  Eur. J. Med. Chem 44
  
  Pages: 4603-4610
- Data Source
  KAKENHI-PROJECT-19550114
[Journal Article] Histone deacetylase inhibitor prodrugs in nanoparticle vector enhanced gene expression in human cancer cells2009
- Author(s)
  Y.Ishii, Y.Hattori, T.Yamada, S.Uesato, Y.Maitani, Y.Nagaoka
- Journal Title
  
  Eur.J.Med.Chem. 44
  
  Pages: 4603-4610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550114
[Journal Article] Histone Deacetylase Inhibitor Prodrugs in Nanoparticle Vector Enhanced Gene Expression in Human Cancer Cells2009
- Author(s)
  Y.Ishii, Y.Hattori, T.Yamada, S.Uesato, Y.Maitani, Y.Nagaoka
- Journal Title
  
  Euro.J.Med.Chem. 44
  
  Pages: 4603-4610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590131
[Journal Article] Effects of Phosphorylation of Immunomodulatory Agent FTY720 (Fingolimod) on Antiproliferative Activity against Breast and Colon Cancer Cells2008
- Author(s)
  Yasuo Nagaoka, Kota Otsuki, Tetsuro Fujita, Shinichi Uesato
- Journal Title
  
  Biol Pharm. Bull. 31(6)
  
  Pages: 1177-1181
- NAID
  110006684337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590110
[Journal Article] Attempt to Detect Natural Anticancer Compounds - Protein Binding through Precursor Ion Scan and MS/MS Measurements.2008
- Author(s)
  J. Negishi, T. Shirahama, Y. Nagaoka, Y. Takemoto, S. Uesato.
- Journal Title
  
  J. Pharm. Soc. Japan 128
  
  Pages: 1317-1323
- NAID
  110006873990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550114
[Journal Article] Attempt to Detect Natural Anticancer Compounds-Protein Binding through Precursor Ion Scan and MS/MS Measurements2008
- Author(s)
  Negishi J., Shirahama T., Nagaoka Y., Takemoto Y., Uesato S
- Journal Title
  
  The Pharmaceutical Society of Japan 128
  
  Pages: 1317-1323
- NAID
  110006873990
- Data Source
  KAKENHI-PROJECT-19550114
[Journal Article] Potent histone deacetylase inhibitors : N-hydroxybenzamides with antitumor activities.2004
- Author(s)
  S.Uesato, et al.
- Journal Title
  
  Bioorg.& Med.Chem. 12
  
  Pages: 4351-4360
- Data Source
  KAKENHI-PROJECT-15310154
[Journal Article] Inhibitory Effects of 3-O-Acyl-(+)-catechins on Epstein-Barr Virus Activation2003
- Author(s)
  Shinichi Uesato, et al.
- Journal Title
  
  Chem.Pharm.Bull. 51(12)
  
  Pages: 1448-1450
- NAID
  110003615244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310154
[Journal Article] Inhibitory Effects of 3-O-Acyl-(+)-catechins on Epstein-Barr Virus Activation2003
- Author(s)
  Shinichi Uesato, et al.
- Journal Title
  
  Chem. Pham. Bull. 51(12)
  
  Pages: 1448-1450
- NAID
  110003615244
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310154
[Journal Article] Inhibitory effect of cancer cell proliferation by novel histone deacetylase inhibitors involves p21/WAF1 induction and G2/M arrest.
- Author(s)
  S.Uesato, et al.
- Journal Title
  
  Biol.Pharm.Bull. (Accepted on Feb.2005)(in press)
- Data Source
  KAKENHI-PROJECT-15310154
[Presentation] Novel HDAC1/2 isoform-specific inhibitor K560 ameliorates MPP+/MPTP-mediated experimental Parkinson’s disease2016
- Author(s)
  Chi-Jing Choong, Tsutomu Sasaki, Hideki Hayakawa, Toru Yasuda, Kousuke Baba, Yoshiyuki Hirata, Shinichi Uesato, and Hideki Mochizuki
- Organizer
  AOPMC 2016 (5th Asian and Oceanian Parkinson’s Disease and Movement Disorders Congress)
- Place of Presentation
  MANILA, PHILIPPINES
- Year and Date
  2016-03-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390222
[Presentation] Efficacy and implications of isoform selective Histone deacetylase inhibitors for cerebral ischemia2016
- Author(s)
  Sasaki T, Chonng Chi-Jing, Watanabe A, Kanki H, Yukami T, Hayakawa H, Yasuda T, Baba K, Sakaguchi M, Uesato S, Mochizuki H
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-24390222
[Presentation] アイソフォーム特異的HDAC阻害剤による虚血性脳血管障害の治療検討2015
- Author(s)
  佐々木　勉、鐘　其静、渡邊　彰弘、神吉　秀明、馬場　孝輔、平田　佳之、坂口　学、上里　新一、望月　秀樹
- Organizer
  第33回日本神経治療学会総会 The 33rd Annual Meeting of Japanese Society of Neurological Therapeutics
- Place of Presentation
  名古屋
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-24390222
[Presentation] Efficacy and implications of selective class I or II Histone deacetylase inhibitors for neurological disorders.2015
- Author(s)
  CJ Choong, T Sasaki, H Hayakawa, K Baba, Watanabe A, Y Hirata, S Uesato and H Mochizuki
- Organizer
  17th Annual Meeting of the American Society for Experimental NeuroTherapeutics (ASENT 2015)
- Place of Presentation
  Georgetown University Hotel And Conference Center, District of Columbia, Washington, USA
- Year and Date
  2015-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390222
[Presentation] A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease.2015
- Author(s)
  Chi-Jing Choong, Tsutomu Sasaki, Hideki Hayakawa, Toru Yasuda, Kousuke Baba, Yoshiyuki Hirata, Shinichi Uesato, and Hideki Mochizuki
- Organizer
  XXI World Congress on Parkinson’s Disease and Related Disorders. IAPRD 2015
- Place of Presentation
  Milan, Italy
- Year and Date
  2015-12-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390222
[Presentation] Efficacy and implications of selective class I or II Histone deacetylase inhibitors for ischemic brain injury.2014
- Author(s)
  Sasaki T, Choong CJ, Watanabe A, Hirata Y, Sanosaka M, Yukami T, Kitagawa K, Takemori H, Uesato S, Mochizuki H.
- Organizer
  American Neurological Association's 2014 Annual Meeting
- Place of Presentation
  Baltimore Marriott Waterfront Hotel, Maryland, USA
- Year and Date
  2014-10-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390222
[Presentation] ヒストン脱アセチル化酵素阻害剤とその誘導体のリポフェクションに及ぼす影響2012
- Author(s)
  長岡康夫, 吉野宏美, 小林真理子, 置田裕子, 中野宏樹, 上里新一
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] リポフェクション効率向上効果を有するプロドラッグ化ヒストン脱アセチル化酵素阻害剤2011
- Author(s)
  置田裕子、中野宏樹、吉田耕平、吉野宏美、上里新一、服部喜之、米谷芳枝、長岡康夫
- Organizer
  日本薬学会131年会
- Place of Presentation
  グランシップツインメッセ静岡
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] Histone Deacetylase Inhibitors as Lipofection Enhancer2011
- Author(s)
  H. Yoshino, M. Kobayashi, H. Okita, H. Nakano, S. Uesato, Y. Nagaoka
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] 類型の異なるヒストン脱アセチル化酵素阻害剤がリポフェクション効率におよぼす影響2011
- Author(s)
  吉野宏美、置田裕子、中野宏樹、服部喜之、米谷芳枝、上里新一、長岡康夫
- Organizer
  日本薬学会131年会
- Place of Presentation
  グランシップツインメッセ静岡
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] Histone Deacetylase Inhibitors as Lipofection Enhancer2011
- Author(s)
  H.Yoshino, M.Kobayashi, H.Okita, H.Nakano, S.Uesato, Y.Nagaoka
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] 新規遺伝子発現増強剤DDTS-K-1822010
- Author(s)
  中野宏樹、置田裕子、石井佑太、長岡康夫、上里新一、服部喜之、米谷芳枝
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山大学
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] Acyl Suberoylanilide Hydroxamic Acid as Lipofection Enhancer2010
- Author(s)
  H. Nakano, S. Uesato, Y. Nagaoka
- Organizer
  11th Tetrahedron Symposium
- Place of Presentation
  北京大学
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] MEK阻害剤とHDAC阻害剤の併用による抗腫瘍効果増強-Xenograftでの検討-2010
- Author(s)
  坂元利彰、藤尾康祐、梶川修平、上里新一、渡邉一石、谷村進、尾崎恵一、河野通明
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪府
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22300340
[Presentation] Prodrugs of Histone Deacetylase Inhibitor K-182 Enhanced Expression of Genes Transfected with Cationic Cholesterol-Based Nanoparticle Vector2010
- Author(s)
  H.Okita, Y.Ishii, S.Uesato, Y.Hattori, Y.Maitani, Y.Nagaoka
- Organizer
  11th Tetrahedron Symposium
- Place of Presentation
  北京大学(中国)
- Year and Date
  2010-06-22
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] Prodrugs of Histone Deacetylase Inhibitor K-182 Enhanced Expression of Genes Transfected with Cationic Cholesterol-Based Nanoparticle Vector2010
- Author(s)
  H. Okita, Y. Ishii, S. Uesato, Y. Hattori, Y. Maitani, Y. Nagaoka
- Organizer
  11th Tetrahedron Symposium
- Place of Presentation
  北京大学
- Data Source
  KAKENHI-PROJECT-21590131
[Presentation] モノクローナル抗体を反応場としたタキソール合成の試み-抗クキソールモノクローナル抗体の作製2009
- Author(s)
  武本佳樹, 白浜辰弥, 河野武幸, 辻琢己, 盛實祐希, 長岡康夫, 上里新一
- Organizer
  日本薬学会129年会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19550114
[Presentation] 硫黄原子を有する新規ヒストン脱アセチル化酵素阻害剤の創生2009
- Author(s)
  清川真吾、長岡康夫、上里新一
- Organizer
  日本薬学会第129年会要旨集2 P.151
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-19590110
[Presentation] モノクローナル抗体を反応場としたタキソール合成の試み-抗タキソールモノクローナル抗体の作製2009
- Author(s)
  武本佳樹, 白浜辰弥, 河野武幸, 辻琢己, 盛實祐希, 長岡康夫, 上里新一
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19550114
[Presentation] 非ウイルスベクターによる外部導入遺伝子の発現を増強するヒストン脱アセチル化酵素阻害剤プロドラッグの開発2009
- Author(s)
  石井佑太、山田敏晴、濱本和隆、田中菜津子、上里新一、長岡康夫、服部喜之、米谷芳枝
- Organizer
  日本薬学会第129年会要旨集4 P.215
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-19590110
[Presentation] 新規細胞周期M期制御化合物の抗がん活性と関連化合物の構造活性相関について2009
- Author(s)
  瓦谷泰之, 平田佳之, 長岡康夫, 原田知彦, 上里新一, 芝野真喜雄, 谷口雅彦, 安田正秀, 馬場きみ江
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東大本郷
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-19550114
[Presentation] ニュートラルロススキャン法およびMS/MS法を用いたタキソール-タンパク質複合体形成の確認について2009
- Author(s)
  白浜辰弥, 武本佳樹, 山本智加, 根岸淳, 長岡康夫, 上里新一
- Organizer
  日本薬学会第129年会
- URL
  http://pharm.life-bio.kansai-u.ac.jp
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19550114
[Presentation] Novel M-phase regulating compounds comprising a nitrooxymethyl group in the molecule2009
- Author(s)
  Uesato S., Kawaratani Y., Nagaoka Y
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-19550114
[Presentation] 新規経口ヒストン脱アセチル化酵素阻害剤K-197の抗腫瘍効果について2009
- Author(s)
  上里新一、清川真吾、平田佳之、長岡康夫、芝野真喜雄、谷口雅彦、安田正秀、馬場きみ江
- Organizer
  日本薬学会第129年会要旨集2 P.151
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-19590110
[Presentation] ニュートラルロスキャン法およびMS/MS法を用いたタキソールータンパク質複合体形成の確認について2009
- Author(s)
  白浜辰弥, 武本佳樹, 山本智加, 根岸淳, 長岡康夫, 上里新一
- Organizer
  日本薬学会129年会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19550114
[Presentation] 正電荷ナノ粒子ベクターによる外部導入遺伝子の発現を増強するヒストン脱アセチル化酵素阻害剤プロドラッグの開発2008
- Author(s)
  長岡康夫、山田敏晴、石井佑太、濱本和隆、田中菜津子、上里新一、服部喜之、米谷芳枝
- Organizer
  第27回メディシナルケミストリーシンポジウム要旨集p.330-332
- Place of Presentation
  メルパルク大阪
- Data Source
  KAKENHI-PROJECT-19590110
[Presentation] 正電荷ナノ粒子ベクターによる外部導入遺伝子の発現を増強するヒストン脱アセチル化酵素阻害剤プロドラツグの開発2008
- Author(s)
  長岡康夫, 山田敏晴, 石井佑太, 濱本和隆, 田中菜津子, 上里新一, 服部喜之, 米谷芳枝
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪(メルパルク大阪)
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-19590110
[Presentation] 経口性ヒストン脱アセチル化酵素阻害剤K-197の開発2008
- Author(s)
  清川真吾、前田泰司、平田佳之、長岡康夫、上里新一(大阪薬大)芝野真喜雄、谷口雅彦、安田正秀、馬場きみ江
- Organizer
  第27回メディシナルケミストリーシンポジウム要旨集p.142-143
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590110

1. NAGAOKA Yasuo (90243039)

# of Collaborated Projects: 7 results

# of Collaborated Products: 33 results
2. KOUNO Takeyuki (50178224)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. HATTORI Yoshiyuki (90350222)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. INOUE KENICHIRO (40025713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. UEDA SHINICHI (20025688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. FUJITA TETSURO (40027024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KOHNO Michiaki (00027335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. OZAKI Kei-ichi (50252466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TANIMURA Susumu (90343342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. TOKIMOTO KEISUKE (20088842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. sasaki tsutomu (20534879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
12. kitagawa kazuo (70301257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. takemori hiroshi (90273672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. mochiduki hideki (90230044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
15. 住吉孝明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

uesato shinnichi 上里 新一

UESATO Shinichi 上里 新一

UESATO SHINICHI 上里 新一

Research Projects

Research Products

Co-Researchers

The role and mechanisms of TORC and HDAC signaling pathway and therapeutic new-class small compounds for neurological disease

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Targeting the ERK-MAP kinase pathway in cancer therapy

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Development of cationic histone deacetylase inhibitors as enhancer of gene transfection and expression

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Attempted synthesis of taxol utilizing anti-taxol monoclonal antibody as a as a chiral mouldPrincipal Investigator

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Synthesis of Histone Deacetylase Inhibitors Toward the Development of DDS

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Design of the anti-tumor agents targeting the functional proteins involved in cancer cell growthPrincipal Investigator

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モノクローナル抗体を反応場として用いた天然抗がん剤の新規合成法の開発Principal Investigator

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セコイリドイド配糖体の生合成研究

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Drug development for antimicrobial and immunodepressive substrances produced by wood-rotting fungi

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[Journal Article] Discovery of new low-molecular-weight p53-Mdmx disruptors and their anti-cancer activities.2016

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[Journal Article] A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease.2016

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[Journal Article] Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models2013

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[Journal Article] Anti-tumor activity of new orally bioavailable 2-amino-5-(thiophen-2-yl) benzamide-series histone deacetylase inhibitors, possessing an aqueous soluble functional group as a surface recognition domain2012

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[Journal Article] Antitumor effect of liposomal histone deacetylase inhibitor-lipid conjugates in vitro2011

Author(s)

uesato shinnichi 上里新一

UESATO Shinichi 上里新一

UESATO SHINICHI 上里新一