MARUYAMA Hiroko 丸山弘子

… Alternative Names

来馬弘子クルマヒロコ

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Researcher Number	50129269
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2020: 北里大学, 医療衛生学部, 准教授 2010 – 2013: 北里大学, 医療衛生学部, 准教授 1993: Kitasato University School of Hygienic Sciences Lecturer, 衛生学部, 講師 1990 – 1992: 北里大学, 衛生学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Food science Except Principal Investigator 医学一般 / General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine)
Keywords	Principal Investigator タウ蛋白質リン酸化 / タウ蛋白質 / アルツハイマー病 / 食事リズム / 脳インスリン抵抗性 / インスリン抵抗性 / 概日時計 / インスリン / アミロイドβ / 血糖値 … More / 高脂肪食 / アルツハイマー症 / BEMAL-1 / βアミロイド / Tauタンパク質リン酸化 / BMAL-1 / 時計遺伝子 / 運動変化 / 摂食時間変更 / 概日リズム / アルツハイマー / タウタンパク質 / βアミロイドタンパク質 / 免疫組織染色 / 脳神経疾患 / 抗酸化物質 / 位相X線画像 / Tau蛋白質リン酸化 / Tau蛋白質 / 位相 X 線画像 / クルクミン / βアミロイド蛋白質 … More Except Principal Investigator N-[methyl-^<14>C]-nitrosodimethylamine / RI標識発がん物質 / あまのり / 食用海藻 / 食物繊維 / AT1a / angiotensin受容体 / 自己免疫型I型糖尿病モデル / 肺粘膜免疫系 / 糖尿病 / 八味丸 / radio-labeled carcinogen / bioaccumulation / polydextrose / cellulose / binding of carcinogen / algal dietary fiber / DMNA / ほそめこんぶ / 海藻抽出物 / 非水溶性食物繊維 / 水溶性食物繊維 / 生体内蓄積 / ポリデキストロース / セルロース / 発癌物質との結合 / DMBA-Induced Mammary Carcinoma / G- H DMBA / RI-Laeled Carcinogen / Laver / Kelp / Dietary Seaweeds / Dietary Fiber / DNA結合軽減 / 標的臓器到達軽減 / 体内吸収軽減 / DMBA誘発ラット乳癌 / [Gー ^3H]DMBA / RI標識発癌物質 / 昆布 / 上気道粘膜免疫機構 / オリゴ糖 / 抗炎症作用 / IRAK-M / 粘膜炎 / 漢方薬 / 制御性分子 / 抗がん剤 / パイエル板 / 小腸上皮細胞 / 上気道粘膜免疫系 / 粘膜炎症 / メソトレキセート / 補中益気湯 Less

Analysis of the molecular mechanism of circadian clock and cerebral insulin resistance involving in beta-amyloid depositionPrincipal Investigator
- Principal Investigator
  
  MARUYAMA Hiroko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kitasato University
Elucidation of immunoabnormality on plumonary mucosal immune system of streptozotocin-induced type I diabetes mice model and analysis of improving effect of Hachimigan
- Principal Investigator
  
  Kiyohara Hiroaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Kitasato University
Elicidation of action mechanism of Hochuekkito through immunomodulation of intestinal epithelial cells
- Principal Investigator
  
  KIYOHARA Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kitasato University
Antioxidant induced decrement of β-amyloid deposits by phase contrast X-ray techniquePrincipal Investigator
- Principal Investigator
  
  MARUYAMA Hiroko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kitasato University
In vitro binding of the carcinogen N-[methyl-^<14>C]-nitrosodimethylamine by algal dietary fibers and their role in reducing its bioaccumulation.
- Principal Investigator
  
  YAMAMOTO Ichiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医学一般
- Research Institution
  Kitasato University School of Hygienic Sciences
Attenuating Effect by Dietary Fibers of Orally Given Ri-Labeled Carcinogen Through Intestinal Tract
- Principal Investigator
  
  YAMAMOTO Ichiro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医学一般
- Research Institution
  Kitasato University

All 2021 2020 2019 2014 2013 2012

All Journal Article Presentation

[Journal Article] Ethanol fixed brain imaging by phase-contrast X-ray technique. Journal of Physics2013
- Author(s)
  Tohoru Takeda, Thet-Thet-Lwin, Takuya Kunii, Ryota Sirai, Takahito Ohizumi, Hiroko Maruyama, Kazuyuki Hyodo, Akio Yoneyama, and Kazuhiro Ueda
- Journal Title
  
  Conference Series
  
  Volume: 425 Issue: 2 Pages: 1-4
- DOI
  10.1088/1742-6596/425/2/022004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580145
[Journal Article] Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito, and its active ingredients2013
- Author(s)
  Sekiya M, Kiyohara H, Maruyama H, Yabe T, Yamada H
- Journal Title
  
  J. Nat. Med.
  
  Volume: 67 Pages: 626-635
- NAID
  40019665918
- Data Source
  KAKENHI-PROJECT-23590895
[Journal Article] Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito,and its active ingredients2012
- Author(s)
  Michiko Sekiya, Hiroaki Kiyohara, Hiroko Maruyama, Takeshi Yabe, Haruki Yamada
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 2012 Issue: 3 Pages: 1-10
- DOI
  10.1007/s11418-012-0724-1
- NAID
  40019665918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 食事時間の変化と高脂肪食が運動時間や時計遺伝子発現に及ぼす影響2021
- Author(s)
  五味未早希、伊藤芙美佳、井上任平、大屋瑞穂、寺尾沙季、鴇田智里、丸山弘子
- Organizer
  第41回日本肥満学会・第38回日本肥満症治療学会
- Data Source
  KAKENHI-PROJECT-18K11108
[Presentation] FDG-バイオラジオグラフィを用いたアルツハイマーモデルマウス脳における糖代謝の解析2021
- Author(s)
  五味未早希、丸山弘子、佐々木徹
- Organizer
  第58回アイソトープ・放射線研究発表会
- Data Source
  KAKENHI-PROJECT-18K11108
[Presentation] 摂食時間の変更が脳内の炎症に及ぼす影響2021
- Author(s)
  五味未早希、川上文貴、ティティルイン、高橋博之、丸山弘子
- Organizer
  第21回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-18K11108
[Presentation] 概日リズムの変化が時計遺伝子転写因子BMAL1の発現に及ぼす影響2020
- Author(s)
  五味未早希、丸山弘子
- Organizer
  第20回日本抗加齢学会
- Data Source
  KAKENHI-PROJECT-18K11108
[Presentation] ワカメ添加高脂肪食がTau蛋白質のリン酸化および βアミロイドの蓄積に及ぼす影響2019
- Author(s)
  平野拓・五味未早希・今井基貴・西川裕美・宮内麻織・丸山弘子
- Organizer
  第18日本応用藻類学会
- Data Source
  KAKENHI-PROJECT-18K11108
[Presentation] ワカメ添加高脂肪摂食マウスのTau蛋白質のリン酸化に及ぼす分子病態的解析2019
- Author(s)
  丸山弘子・平野拓・今井基貴
- Organizer
  第40日本肥満学会
- Data Source
  KAKENHI-PROJECT-18K11108
[Presentation] 高血糖病態下における呼吸器粘膜免疫系の変化と八味地黄丸の作用の解析2014
- Author(s)
  黄　子綾、丸山弘子、永井隆之、鄭　美和、清原寛章
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市、熊本県（熊本大学）
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 高血糖病態下における呼吸器粘膜免疫系の変化と八味地黄丸の作用の解析2014
- Author(s)
  黄子綾、丸山弘子、永井隆之、鄭美和、清原寛章
- Organizer
  日本薬学会第134年会
- Place of Presentation
  (日本薬学会第134年会要旨集)
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 補中益気湯の抗がん剤誘発小腸上皮傷害改善作用の解析2013
- Author(s)
  関谷路子、清原寛章、丸山弘子、山田陽城
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 補中益気湯の抗がん剤誘発小腸上皮傷害改善作用の解析2013
- Author(s)
  関谷路子、清原寛章、丸山弘子、山田陽城
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川(日本薬学会第133年会要旨集3 p.195)
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 補中益気湯のパイエル板免疫機能に対する調節作用の解析2012
- Author(s)
  関谷路子、清原寛章、矢部武士、丸山弘子、山田陽城
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道(日本薬学会第132年会要旨集3 p.83)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 補中益気湯の作用の腸管免疫系からの解析2012
- Author(s)
  清原寛章、関谷路子、西本裕紀、永井隆之、丸山弘子、山田陽城
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] メソトレキセート誘発小腸上皮傷害に対する補中益気湯の作用の解析2012
- Author(s)
  関谷路子、清原寛章、丸山弘子、山田陽城
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 補中益気湯の作用の腸管免疫系からの解析2012
- Author(s)
  清原寛章、関谷路子、西本裕紀、永井隆之、丸山弘子、山田陽城
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京(J. Trad. Med. 29 (supple) p.54)
- Year and Date
  2012-09-02
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] 補中益気湯のパイエル板免疫機能に対する調節作用の解析2012
- Author(s)
  関谷路子、清原寛章、矢部武士、丸山弘子、山田陽城
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] メソトレキセート誘発小腸上皮傷害に対する補中益気湯の作用の解析2012
- Author(s)
  関谷路子、清原寛章、丸山弘子、山田陽城
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京(J. Trad. Med. 29 (supple) p.71)
- Year and Date
  2012-09-02
- Data Source
  KAKENHI-PROJECT-23590895
[Presentation] クルクミンによるβアミロイド蛋白質産生抑制効果の基礎的検討2012
- Author(s)
  大泉孝仁、丸山弘子、國井琢矢、白井亮多、秋田久直、川上文貴、大部誠、武田徹
- Organizer
  第66回日本栄養・食糧学会講演要旨集
- Place of Presentation
  仙台
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22580145
[Presentation] クルクミンによるβアミロイド蛋白質産生抑制効果の基礎的検討2012
- Author(s)
  大泉孝仁、丸山弘子、國井琢矢、白井亮多、秋田久直、川上文貴、大部誠、武田徹
- Organizer
  第66回日本栄養・食糧学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22580145
[Presentation] アルツハイマーモデルマウスにおけるクルクミンの発症抑制効果2012
- Author(s)
  大泉孝仁、丸山弘子、國井琢矢、白井亮多、秋田久直、川上文貴、大部誠、武田徹
- Organizer
  第25回北里大学バイオサイエンスフォーラム
- Place of Presentation
  東京
- Year and Date
  2012-08-02
- Data Source
  KAKENHI-PROJECT-22580145

1. KAWAKAMI Fumitaka (50511896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. KIYOHARA Hiroaki (70161601)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. YAMAMOTO Ichiro (10050361)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TAKEDA Tohoru (10197311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. YABE Takeshi (40239835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. OIKAWA Tetsuro (10370165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 永井隆之 (00172487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐々木徹 (30158927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MORIGUCHI Masahide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MARUYAMA Hiroko 丸山 弘子

来馬 弘子 クルマ ヒロコ

Research Projects

Research Products

Co-Researchers

Analysis of the molecular mechanism of circadian clock and cerebral insulin resistance involving in beta-amyloid depositionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of immunoabnormality on plumonary mucosal immune system of streptozotocin-induced type I diabetes mice model and analysis of improving effect of Hachimigan

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elicidation of action mechanism of Hochuekkito through immunomodulation of intestinal epithelial cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antioxidant induced decrement of β-amyloid deposits by phase contrast X-ray techniquePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vitro binding of the carcinogen N-[methyl-^<14>C]-nitrosodimethylamine by algal dietary fibers and their role in reducing its bioaccumulation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Attenuating Effect by Dietary Fibers of Orally Given Ri-Labeled Carcinogen Through Intestinal Tract

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ethanol fixed brain imaging by phase-contrast X-ray technique. Journal of Physics2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito, and its active ingredients2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito,and its active ingredients2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] 食事時間の変化と高脂肪食が運動時間や時計遺伝子発現に及ぼす影響2021

Author(s)

Organizer

Data Source

[Presentation] FDG-バイオラジオグラフィを用いたアルツハイマーモデルマウス脳における糖代謝の解析2021

Author(s)

Organizer

Data Source

[Presentation] 摂食時間の変更が脳内の炎症に及ぼす影響2021

Author(s)

Organizer

Data Source

[Presentation] 概日リズムの変化が時計遺伝子転写因子BMAL1の発現に及 ぼす影響2020

Author(s)

Organizer

Data Source

[Presentation] ワカメ添加高脂肪食がTau蛋白質のリン酸化および βアミロイドの蓄積に及ぼす影響2019

Author(s)

Organizer

Data Source

[Presentation] ワカメ添加高脂肪摂食マウスのTau蛋白質のリン酸化に及ぼす分子病態的解析2019

Author(s)

Organizer

MARUYAMA Hiroko 丸山弘子

来馬弘子クルマヒロコ

[Presentation] 概日リズムの変化が時計遺伝子転写因子BMAL1の発現に及ぼす影響2020