SAIGO Kaoru 西郷薫

Researcher Number	50136454
External Links
Affiliation (based on the past Project Information) *help	2006: The University of Tokyo, Department of Biophysics and Biochemistry, Graduate School of Science, Professor, 大学院理学系研究科, 教授 1993 – 2005: 東京大学, 大学院・理学系研究科, 教授 2003 – 2004: 東京大学, 大学院理学系研究科, 教授 2001: 東京大学, 大学院・理学研究科, 教授 1993 – 1994: 東京大学, 大学院理学系研究科, 教授 … More 1988 – 1994: Faculty of Science, the University of Tokyo, 理学部, 教授 1988: 東京大学, 理学部・, 教授 1987: 九州大, 医, 助教授 1986 – 1987: 九州大学, 医学部, 助教授 1986: 九大, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Molecular biology / Biological Sciences / 分子遺伝学・分子生理学 / Developmental biology / 基礎ゲノム科学 Except Principal Investigator Biological Sciences / Molecular biology / 遺伝学 / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator ショウジョウバエ / Bar / ホメオボックス遺伝子 / RNAi / 位置情報 / 肢形成 / ホメオボックス / 肢 / hedgehog / エンハンサー … More / リボザイム / 複眼 / 遠近軸 / dpp / ヘジホッグ / wingless / Drosophila / FGF / siRNA / ヘッジホッグ / 区画化 / Aristaless / Lim1 / Wingless / RNA interference / human / 神経分化 / 光受容細胞 / DNA結合部位 / 分化 / エイズ / ウイロイド / HIV / 鋸型リボザイム / RNA切断 / アンチセンスRNA / eagle / アクソン / 細胞分化 / 転写制御 / Bar遺伝子 / ウイングレス / ヒト / バー遺伝子 / 変異体ライブラリー / emc / インバートリピート / 形質転換 / P因子 / レトロトランスポゾン / チロシンキナーゼ / Wnt / Frizzled / off-target / mouse / pxb / Branchless / Breathless / genome / バ- / フォトリセプタ- / RNAライゲ-ス / STobRV / トランスアクチベ-タ- / シグナルトランスダクション / sTobRV / 複眼分化 / 原基 / RNAライゲーション / 2'-5'リン酸ジエステル結合 / 切断反応 / 2'、3'環状リン酸 / 相補鎖RNA / ゲノム進化 / 後部区画 / ptc / 転写制御因子 / 神経細胞 / トランスジェニックハエ / フェールセーフ / ニューロブラスト / ホルモンレセプター / 細胞系譜 / FMN / 還元酵素 / ニトロ還元酵素 / フラビン還元酵素 / コンバージェンス / 試験管内進化 / 発光細菌 / 大腸菌 / MAPキナーゼ / エンハンサー・アッセイ / インスレーター / gypsy / シグナル伝達 / バ-(Bar) / 分節化 / Distalless / ヘジホグ遺伝子 / バイオアッセイ / アリスタレス・ライク遺伝子 / ウイングレス受容体 / 背中形成 / LIMホメオボックス遺伝子 / dlim-1 / カドヘリン・リピート / das / 細胞接着 / 細胞の方向性 / Dpp / コンパートメント / 受容体 / Dfrizzled3 / Lim 1 / Arrow / cll / arisataless / RNAiベクター / 変異体ライブラリ / ゲノム / ガン遺伝子 / コピア / キメラ / ホメオポックス遺伝子 / ニューロン / lacZ / 腹部神経節 / 複眼異常 / アンキリンリピート / forted / サプレッサー / homeobox gene / enhaner / neuron / photoreceptor / lac Z / 中枢神経系 / イ-グル / スラロイドホルモン / ウイニングレス / 神経発生 / エングレイルド / 正中線 / ジアホレース / ニトロリダクテ-ス / ニューロンブラスト / 前後軸 / 梯子状神経 / 神経芽細胞 / 分泌蛋白 / オートクリン / 中枢神経 / パラクリン / central nervous system / steroid hormone / axonogenesis / engrailed / WNT / モルフォゲン / モルファゲン / Yan / RNA干渉 / マウス / 有効siRNA配列 / ウェブサイト / 遺伝子機能破壊 / 哺乳類 / 全ゲノム遺伝子 / RNA干渉法 / Dicer / eIF2C1 / インターフェロン / ヒトゲノム / 哺乳類培養細胞 / ds RNA / SiRNA / ルシフェラーゼ / アポトーシス / effective siRNA / web site / ブランチレス / ウィングレス / ビセラルメソダーム / ブレスレス / aristaless / Ras / HH / トラキア / 気管 / フィードバック / Hedgehog / visceral mesoderm / 機能解析 / siRNAライブラリ / RNAi関連遺伝子 / humna / functional genomics / siRNA library / RNAi-related gene / トデンスポゾン / Lトコトランスポゾン / 転移機構 / 奇形 / 形態形成 / トランスポゾン / 複眼形成 / Retrotransposon / Transposon / Transposoble elements / Complex Eyes / Morphogenesis … More Except Principal Investigator ショウジョウバエ / 転写 / 動く遺伝子 / 突然変異 / 遺伝子発現 / 核内因子 / 癌細胞 / 制御領域 / 分子進化 / 反復配列 / 分子適応 / 遺伝暗号 / 生体高次機能 / ホメオボックス / RNAi / エンハンサー / メチル化 / 転移性因子 / Pーエレメント / 形態形成 / ホメオボックス遺伝子 / P因子 / CNP / 分子生物学 / 細胞情報変換 / 遺伝解析 / エンバンサ-トラップ / 神経分子生物学 / 筋蛋白遺伝子 / 細胞情報伝達 / 遺伝子解析 / 線虫 / アラビドプシス / ゼブラフィシュ / Dicer / RNaseIII / PIWI / siRNA / 二本鎖RNA / 結晶 / 遺伝子サイレンシング / リボヌクレアーゼIII / モルフォゲン / 位置情報 / 発現制御 / データベース / ホモロジー / がん遺伝子 / 立体構造 / 系統樹 / 異常発現 / エンハンサープロモーター / 無細胞転写系 / cDNAクローン / コピア / G6PD / 光受容細胞 / raf情報伝達径路 / 神経細胞分裂調節 / レトロポゾン / 神経細胞 / 癌遺伝子 / キイロショウジョウバエ / レトロウイルス / 遺伝子導入法 / 培養細胞 / 遺伝子発現調節 / 発生異常突然変異体 / トランスポゾン / raf / フォスクオリパーゼC / Tom因子 / グリア細胞 / マウス / ヒト / ドロソフィラ / 胎生期 / オリゴデンドロサイト / 選択スプライシング / RT-PCR / 遺伝子 / 相同遺伝子 / プロモター / Gene expression / Glial cell / Oligodendrocyte / Mouse / Human / Embryo / ショジョバエ / 変異体バンク / 遺伝子機能解析 / ゲノム機能解析 / 遺伝学 / ゲノム / 昆虫 / 発生・分化 / ゲノム機能 / Drosophila / mutant fly bank / gene function analysis / functional genomics Less

Construction of siRNA library for human functional genomics and hunting of RNAi-related genes.Principal Investigator
- Principal Investigator
  
  SAIGO Kaoru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  The University of Tokyo
Functional Genomics by comprehensive RNAi mutant fly bank in Drosophila
- Principal Investigator
  
  UEDA Ryu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
RNAiを用いたショウジョウバエ変異体ライブラリーの構築Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
RNAi酵素・RNA複合体及び関連蛋白質の構造解析
- Principal Investigator
  
  善野修平
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
位置情報の認識による領域の区画化とその形態形成における役割の解明
- Principal Investigator
  
  小嶋徹也
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
RNAiを用いたショウジョウバエ変異体ライブラリーの構築Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Establishment of human and mammalian RNAi for effective and systematic functional genomics.Principal Investigator
- Principal Investigator
  
  SAIGO Kaoru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
Basdicmolecularmechanisms for tissue and organ formaiton: HH and FGF-dependent and regulation of positional information and compartment formationPrincipal Investigator
- Principal Investigator
  
  SAIGO Kaoru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  The University of Tokyo
肢形成の分子機構と関連シグナル伝達遺伝子の探索Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子の二段階転写調節による肢芽の区画化と遠近軸形成Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
RNAiを用いたショウジョウバエ変異体ライブラリーの構築Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
肢形成の分子機構と関連シグナル伝達遺伝子の探索Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子の二段階転写調節による肢芽の区画化と遠近軸形成Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
バイオアッセイによるヒト基本エンハンサーの探索と網羅的cDNAの機能解析法の開発Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
肢形成の分子機構と関連シグナル伝達遺伝子の探索Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子の二段階転写調節による胚芽の区画化と遠近軸形成Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
POSITIONAL INFORMATION REGULATION DURING LEG DEVELOPMENT THROUGH FGF AND WNT SIGNALINGPrincipal Investigator
- Principal Investigator
  
  SAIGO Kaoru
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Molecular biology
- Research Institution
  THE UNIVERSITY OF TOKYO
バイオアッセイによる基本エンハンサーの探索と網羅的なcDNA機能解析法の開発Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
肢形成の分子機構と関連シグナル伝達遺伝子の探索Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子の二段階転写調節による肢芽の区画化と遠近軸形成Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子のfail-safe機構と細胞機能分化Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子のfail-safe機構と細胞分化機能Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
形態形成遺伝子の分子進化Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Molecular mechanisms of central nervous system formationPrincipal Investigator
- Principal Investigator
  
  SAIGO Kaoru
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
ショウジョウバエにおける細胞及び器官分化の分子機構Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子のfail-safe機構と細胞機能分化Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
形態形成遺伝子の分子進化Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
モデル実験系を用いた生体高次機能解析
- Principal Investigator
  
  堀田凱樹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
ショウジョウバエにおける細胞及び器官分化の分子機構Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ホメオボックス遺伝子のfail-safe機構と細胞の機能分化Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Roles of homeobox genes in neural development and behaviorPrincipal Investigator
- Principal Investigator
  
  SAIGO Kaoru
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
Gene Expression of Glial Cells
- Principal Investigator
  
  KIRIHARA Tadashi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Soka University
ショウジョウバエにおける中枢及び末梢神経分化の分子機構Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
RNAの自発的ライゲーションとその進化的意義Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズウイルスRNAの塩基配列特異的リボザイムによる細胞内破壊の可能性の検討Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ショウジョウバエ分子生物学による生体高次機能解析
- Principal Investigator
  
  堀田凱樹
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ショウジョウバエ分子生物学による生体高次機能解析
- Principal Investigator
  
  堀田凱樹
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズウイルスRNAの塩基配列特異的リボザイムによる細胞内破壊の可能性の検討Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
新しいホメオボックス遺伝子BHグル-プによる遺伝子転写制御と細胞分化Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
癌化関連遺伝子の特異的発現機構
- Principal Investigator
  
  藤井義明
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
複眼奇形をもたらすOm遺伝子群の構造解析とそれらの神経分化上果す役割の解明Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo
進化学的視野をもつ分子遺伝学的研究
- Principal Investigator
  
  武藤あきら
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
ショウジョウバエ分子生物学による生体高次機能解析
- Principal Investigator
  
  堀田凱樹
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
高等動物の動く遺伝子とそれを利用した遺伝子発現・調節制御系の分子生物学的研究
- Principal Investigator
  
  石和貞男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  遺伝学
- Research Institution
  Ochanomizu University
進化学的視野をもつ分子遺伝学的研究
- Principal Investigator
  
  武藤〓
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
ショウジョウバエ分子生物学による生体高次機能解析
- Principal Investigator
  
  堀田凱樹
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
癌化関連遺伝子の特異的発現機構
- Principal Investigator
  
  藤井義明
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
進化学的視野をもつ分子遺伝学的研究
- Principal Investigator
  
  武藤〓
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
癌化関連遺伝子の特異的発現機構
- Principal Investigator
  
  藤井義明
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
Mechanisms of Translocation of and Gene Regulation by Transposable Elements in EukaryotesPrincipal Investigator
- Principal Investigator
  
  SAIGO Kaoru
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo
  Kyushu University
ガン遺伝子の機能と構造の推定のためのコンピュータシステムの開発
- Principal Investigator
  
  宮田隆
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
脊椎動物の発癌遺伝子を持つショウジョウバエの作製と遺伝子治療の試みPrincipal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
LトロトランスポゾンのTATA box様配列への特異的挿入とクロマチン構造Principal Investigator
- Principal Investigator
  
  西郷薫
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University

All 2007 2006 2005 2004 2003 2002 Other

All Journal Article Patent

[Journal Article] Guidelines for the selection of functional siRNA sequences for mammalian RNAi.2007
- Author(s)
  Ui-Tei, K., Naito, Y., Saigo, K.
- Journal Title
  
  Methods Mol. Biol. 361
  
  Pages: 201-216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Establishment of cell lines derived from the rat suprachiasmatic nucleus.2007
- Author(s)
  Kawaguchi, S., Shinozaki, A., Obinata, M., Saigo, K., Sakaki, T., Tei, H.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 355
  
  Pages: 555-561
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.2007
- Author(s)
  Kojima, S., Matsumoto, K., Hirose, M., Shimada, M., Nagano, M., Shigeyoshi, Y., Hoshino, S., Ui-Tei, K., Saigo, K., Green, C.B., Sakaki, Y., Tei, H.
- Journal Title
  
  Proc. Natl. Acad. Sci., USA. 104
  
  Pages: 1859-1864
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.2007
- Author(s)
  Sasaki, N., Sasamura, T., Ishikawa, H., Kanai, M., Ueda.R.Saigo, K., Matsuno, K.
- Journal Title
  
  Genes Cells 12
  
  Pages: 89-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Differential microarray analysis of Drosophila mushroom body transcripts using chemical ablation.2006
- Author(s)
  Kobayashi, M., Michaut, L., Ino, A., Honjo, K., Nakajima, T., Maruyama, Y., Mochizuki, H., Ando, M., Ghangrekar, I., Takahashi, K., Saigo, K., Ueda, R., Gehring, W.J., Furukubo-Tokunaga, K.
- Journal Title
  
  Proc. Natl. Acad. Sci., USA 103
  
  Pages: 14417-17722
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] siVirus : web-based antiviral siRNA design software for highly divergent viral sequences.2006
- Author(s)
  Naito, Y., Ui-Tei, K., Nishikawa, T., Takebe, Y., Saigo, K.
- Journal Title
  
  Nucleic Acids Res. 34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Essential notes regarding the design of functional siRNAs for efficient mammalian RNAi.2006
- Author(s)
  Ui-Tei, K., Naito, Y., Saigo, K.
- Journal Title
  
  J. Biomed. Biotechnol. 2006(4)
  
  Pages: 14417-14422
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Molecular cloning and characterization of a novel 3'-phosphoadenosin 5'-phosphosulfate transporter, PAPST2.2006
- Author(s)
  Kamiyama, S., Sasaki, N., Goda, E., Ui-Tei, K., Saigo K., Narimatsu, H., Jigami, Y., Kannagi, R., Irimura, T., Nishihara, S.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 10945-10953
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Control of axonal sprouting and dendrite branching by the Nrg-Ank complex at the neuron-glia interface.2006
- Author(s)
  Yamamoto, M., Ueda, R., Takahashi, K., Saigo, K., Uemura, T.
- Journal Title
  
  Curr. Biol. 16
  
  Pages: 1678-1683
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Crystallization and preliminary X-ray analysis of the C-terminal RNase III domain of human Dicer.2006
- Author(s)
  Takeshita, D., Zenno, S., Lee, W.C., Saigo, K.Nagata K., Tanokura, M.
- Journal Title
  
  Acta Crystallographica F62
  
  Pages: 402-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Crystallization of preliminary X-ray analysis of the PIN domain of human ESTIA.2006
- Author(s)
  Takeshita, D., Zenno, S., Lee, W.C., Saigo, K., Tanokura, M.
- Journal Title
  
  Acta Crystallographica F62
  
  Pages: 656-658
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Wing-to-leg homeosis by Spineless causes an apoptosis regulated by Fish-lips, a novel Leucine-Rich Repeats transmembrane protein.2005
- Author(s)
  Adachi-Yamada, T., Harumoto, T., Sakurai, K., Ueda, R., Saigo, K., 0'Connor, M.B., Nakato, H.
- Journal Title
  
  Mol. Cell. Biol. 25
  
  Pages: 3140-3150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] dsCheck : highly sensitive off-target search software for dsRNA-mediated RNA interference.2005
- Author(s)
  Naito, Y., Yamada, T., Matsumiya, T., Ui-Tei, K., Saigo, K., Morishita, S.
- Journal Title
  
  Nucleic Acids Res. 33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Targeted expression of IP_3 sponge and IP_3 DSRNA impaires sugar taste sensation in Drosophila.2005
- Author(s)
  Usui-Aoki, K., Matsumoto, K., Koganezawa, M., Kohatsu, S., Isono, K., Matsubayashi, H., Yamamoto, M., Ueda, R., Takahashi, K., Saigo, K., Mikoshiba, K., Yamamoto, D.
- Journal Title
  
  J. Neurogenetics 19
  
  Pages: 123-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] RNAi induced in mammalian and Drosophila cells via transfection of dimers and trimers of short interfering RNA.2005
- Author(s)
  Ui-Tei, K., Zenno, S., Juni, A., Saigo, K.
- Journal Title
  
  J. RNAi Gene Silencing 1
  
  Pages: 79-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving inter-and intramolecular interactions.2005
- Author(s)
  Niimura, M., Isoo, N., Takasugi, N., Tsuruoka, M., Ui-Tei, K., Saigo, K., Morohashi, Y., Tomita, T., Iwatsubo, T.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 12967-12975
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Requirements of genetic interactions between Src42A, armadillo and shotgun, a gene encoding E-cadherin, for normal development in Drosophila.2005
- Author(s)
  Takahashi, M., Takahashi, F., Ui-Tei, K., Kojima, T., Saigo, K.
- Journal Title
  
  Development 132
  
  Pages: 2547-2559
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] In vivo RNA interference analysis reveals an unexpected role for GNBP1 in the defense against Gram-positive bacterial infection in Drosophila adults.2004
- Author(s)
  Pili-Floury, S., Leulier, F., Takahashi, K., Saigo, K., Samain, E, Ueda, R., Lemaitre, B.
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 12848-12853
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.2004
- Author(s)
  Ui-Tei, K., Naito, Y., Takahashi, F., Haraguchi, T., Ohki-Hamazaki, H., Juni, A., Ueda, R., Saigo, K.
- Journal Title
  
  Nucleic Acids Res. 32
  
  Pages: 936-948
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] RNA interference induced by transient or stable expression of hairpin structures of double stranded RNA in Drosophila and mammalian cells.2004
- Author(s)
  Ui-Tei, K., Ueda, R., Zenno, S., Takahashi, F., Doi, N., Naito, Y., Yamamoto, M., Hashimoto, N., Takahashi, K., Hamada, T., Tokunaga, T., Saigo, K.
- Journal Title
  
  Molekulyarnaya biologiya 38
  
  Pages: 228-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.2004
- Author(s)
  Ui-Tei, K., Naito, Y., Takahashi, F., Haraguchi, T., Ohki-Hamazaki, H., Juni, A., Ueda, R., Saigo, K.
- Journal Title
  
  Nucleic Acids Res. 32
  
  Pages: 936-948
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] RNA-interference induced by transient or stable expression of hairpin structures of double-stranded RNA in Drosophila and mammalian cells.2004
- Author(s)
  Ui-Tei, K., Ueda, R., Zenno, S., Takahashi, F., Doi, N., Naito, Y., Yamamoto, M., Hashimoto, N., Takahashi, K., Hamada, T., Tokunaga, T., Saigo, K.
- Journal Title
  
  Mol. Biol. 38
  
  Pages: 276-287
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] siDirect : highly effective, target-specific siRNA design software for mammalian RNA interference.2004
- Author(s)
  Naito, Y., Yamada, T., Ui-Tei, K., Morishita, S., Saigo, K.
- Journal Title
  
  Nucleic Acids Res. 32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] In vivo RNA interference analysis reveals an unexpected role for GNBP1 in the defence against Gram-positive bacterial infection in Drosophila adults.2004
- Author(s)
  Pili-Floury, S., Leulier, F., Takahashi, K., Saigo, K., Samain, E., Ueda, R., Lemaitre, B.
- Journal Title
  
  J. Cell Biol. 166
  
  Pages: 12848-12853
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter.2003
- Author(s)
  Kamiyama, S., Suda, T., Ueda, R., Suzuki, M., Okubo, R., Kikuchi, N., Chiba, Y, Goto, S., Toyoda, T., Saigo, K., Watanabe, M., Narimatsu, H., Jigami, Y, Nishihara, S.
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 25958-25963
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] Proteoglycan UDP-galactose : beta-xylose beta1,4galactosyltransferase I is essential for viability in Drosophila melanogaster.2003
- Author(s)
  Takemae, H., Ueda, R., Ohkubo, R., Nakato, H., Izumi, S., Saigo, K., Nishihara, S.
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 15571-15578
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] Requirement of Dicer and eIF2C translation initiation factors for short-interfering-RNA-mediated gene silencing in mammalian cells.2002
- Author(s)
  Doi, N., Zenno, S., Ueda, R., Ohki-Hamazaki, H., Ui-Tei, K., Saigo, K.
- Journal Title
  
  Curr. Biol. 13
  
  Pages: 41-46
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] Requirements of high levels of Hedgehog signaling activity for medial-region cell fate determination in Drosophila leg : identification of pxb, a putative Hedgehog signaling attenuator gene repressed along the anterior-posterior compartment boundary.2002
- Author(s)
  Inaki, M., Kojima, T., Ueda, R., Saigo, K.
- Journal Title
  
  Mech. Develop. 116
  
  Pages: 3-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] Inducible expression of double strand RNA reveals a role of dFADD in the regulation of antibacterial response in Drosophila.2002
- Author(s)
  Leulier, F., Vidal, S.S., Saigo, K., Ueda, R., Lemaitre, B.
- Journal Title
  
  Curr. Biol. 12
  
  Pages: 996-1000
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15011253
[Journal Article] Sequence requirements for effective mammalian RNAi induced by short double-stranded RNAs equal to or more than 22bp in length.
- Author(s)
  Ui-Tei, K., Zenno, S., Saigo, K.
- Journal Title
  
  In; New Research on Antisense Elements (Genetics). Nova Science Publishers, Inc. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Journal Article] Crystal structure of the PIN domain of human telomerase-associated ESTIA.
- Author(s)
  Takeshita, D., Zenno, S., Saigo, K., Tanokura, M.
- Journal Title
  
  Proteins (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201040
[Patent] オリゴまたはポリヌクレオチド2005
- Inventor(s)
  西郷薫
- Industrial Property Rights Holder
  株式会社, バイオシンクタンク
- Industrial Property Number
  2005-019362
- Filing Date
  2005-01-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201040

1. 小嶋徹也 (80262153)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. 堀田凱樹 (30010036)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. 西田育巧 (50107059)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. UEDA Ryu (40353429)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
5. 武藤あきら (80034635)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 藤井義明 (00098146)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 渡辺武 (40028684)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 長田重一 (70114428)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 鈴木義昭 (50132733)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 遠藤英也 (40037320)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. 池村淑道 (50025475)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. 谷藤茂行 (50000774)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. 水野重樹 (90112903)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. 大坪栄一 (10158800)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. 竹市雅俊 (00025454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. 岡田益吉 (60015534)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. UI-TEI Kumiko (50213327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 広川信隆 (20010085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. KIRIHARA Tadashi (50018800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HATTORI Kazue (70228485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 石丸聡 (00203026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 黒岩厚 (20134611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 榎森康文 (60160389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 西賀秀俊 (60131918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 山崎常行 (10108649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 香川弘昭 (10022732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 志村令郎 (60025426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 道上達男 (10282724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 善野修平 (90313204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 宮田隆 (20022692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 長谷川政美 (60011657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 五条堀孝 (50162136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 斉藤信彦 (20063125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 石和貞男 (20017205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 向井輝美 (30091242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 堀浩 (40000814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 藤田忍 (30092323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 野田昌晴 (60172798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 泉龍太郎 (30247291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 高橋邦明 (80370112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 安永照雄

# of Collaborated Projects: 1 results

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42. 宇井久美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results

SAIGO Kaoru 西郷 薫

Research Projects

Research Products

Co-Researchers

Construction of siRNA library for human functional genomics and hunting of RNAi-related genes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional Genomics by comprehensive RNAi mutant fly bank in Drosophila

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNAiを用いたショウジョウバエ変異体ライブラリーの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNAi酵素・RNA複合体及び関連蛋白質の構造解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

位置情報の認識による領域の区画化とその形態形成における役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNAiを用いたショウジョウバエ変異体ライブラリーの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of human and mammalian RNAi for effective and systematic functional genomics.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basdicmolecularmechanisms for tissue and organ formaiton: HH and FGF-dependent and regulation of positional information and compartment formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肢形成の分子機構と関連シグナル伝達遺伝子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ホメオボックス遺伝子の二段階転写調節による肢芽の区画化と遠近軸形成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

RNAiを用いたショウジョウバエ変異体ライブラリーの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肢形成の分子機構と関連シグナル伝達遺伝子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ホメオボックス遺伝子の二段階転写調節による肢芽の区画化と遠近軸形成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

バイオアッセイによるヒト基本エンハンサーの探索と網羅的cDNAの機能解析法の開発Principal Investigator

Principal Investigator

SAIGO Kaoru 西郷薫