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HIROSAWA Shinsaku
広沢 信作
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Researcher Number
50143574
Affiliation (based on the past Project Information)
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2001: 医科歯科大, 助教授
2000: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教授
1998: Medical Department, Associate Professor, 医学部, 助教授
1991 – 1998: 東京医科歯科大学, 医学部, 講師
1993: Tokyo Medical & Dental Univ., Dept.of Medicine, Instructor, 医学部第一内科, 講師
1991: 東京医科歯科大学, 医学部, 助手
1986 – 1988: 東京医科歯科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
Hematology
Keywords
Principal Investigator
プロモーター / アルファ2プラスミンインヒビター / 変異蛋白 / 粗面小胞体 / トロンボモジュリン / 凝固・線溶 / ゲルシフトアッセイ / リンパ腫 / プロテアソーム / alpha_2-plasmin inhibitor
…
More
/ マンノーストリミング / impaired secretion / アルファ2プラスミンインヒビタ- / BCL-6 / Zinc finger / 分泌障害 / プロテアーゼ / ルシフェラーゼ / プロモ-タ- / endoplasmic reticulum / ユビキチン / レチノイド / CATアッセイ / 染色体転座 / BCL6 gene / mutant protein / CATアソセイ / 欠損症 / バンドシフトアッセイ / トランスフェクション / 悪性リンパ腫 / 線溶系 / 切断点 / サイクリックAMP / 発現実験 / α2-プラスミンインヒビター / プラスミン インヒビター / 内皮細胞 / グルコーストリミング / Trans cription factor / 血管内皮細胞 / 発現調節 / オールトランスレチノイン酸
…
More
Except Principal Investigator
アルファ2プラスミンインヒビター / 細胞内輸送 / 分泌障害 / 細胞内輸送障害 / 先天性欠損症 / 遺伝子変異 / プロテインC / アルフア2プラスミンインヒビタ- / Impairement of Secretion / Gene Mutation / 転写調節 / Congenital deficiency of alpha 2 plasmin inhibitor / MLL遺伝子 / FISH / 転座関連遺伝子 / 造血器腫瘍 / 欠損症 / 遺伝子発現 / cDNA / 慢性骨髄性白血病 / 染色体 / Chromosome / アルファ2プラスミンインヒビター欠損症 / EVI-1遺伝子 / Congenital Deficiency / 失天性欠損症 / Intracellular Transport / 血管内皮細胞 / Gene / アルフア2プラスミンインヒビタ-欠損症 / セリンプロテアーゼインヒビター / alpha_2-plasmin inhibitor / 遺伝子 / WT1 / EWS遺伝子 / 遺伝子ファミリー / 血液凝固の制御 / α_2PIーOkinawa / BCL6遺伝子 / インターフェロン / AML1遺伝子 / 血栓溶解 / 線維素溶解 / モノクロナル抗体 / スロンビン / 変異遺伝子 / Alpha 2 plasmin inhibitor / プロテインC欠損症 / 血管内凝固 / RAD54 / 骨・軟部腫瘍 / FISH法 / スロンボモデュリン / HLA
Less
Research Projects
(
16
results)
Co-Researchers
(
19
People)
Project Start Year (Newest)
Project Start Year (Oldest)
変異蛋白質のプロテアゾーム分解における糖鎖のトリミングの役割
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
Study for proteases involved in degradation of mutant alpha_2-plasma inhibitor in a endoplasmic roticela.
Principal Investigator
Principal Investigator
HIROSAWA Shinsaku
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
B細胞リンパ腫に関与する遺伝子(BCL-6)の発癌への関与のメカニズムの研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
転座関連遺伝子によるがんの診断・病態研究
Principal Investigator
鎌田 七男
Project Period (FY)
1996 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Hiroshima University
粗面小胞体を用いたアルファ2プラスミンインヒビターの輸送障害のメカニズムの研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
血管内皮細胞におけるトロンボモジュリン遺伝子の発現制御の研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
B細胞リンパ腫に関与する遺伝子(BCL-5)の同定と発症メカニズムの研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
血管内皮細胞におけるトロンボモジュリン遺伝子の発現制御の研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
遺伝性凝固線溶系蛋白欠損症の発症機転としての変異蛋白の細胞内輸送障害
Principal Investigator
青木 延雄
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
アルファ2プラスミンインヒビター遺伝子のプロモーター領域の研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
遺伝性凝固線溶系蛋白欠損症の発症機転としての変異蛋白の細胞内輸送障害
Principal Investigator
AOKI Nobuo
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
アルファ2プラスミンインヒビター遺伝子のプロモーター領域に結合する蛋白質の同定
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
アルファ2プラスミンインヒビタ-遺伝子の発現調節
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
Intracellular transport of Mutant alpha_2-plasmin inhibitor
Principal Investigator
AOKI Nobuo
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
Studies on the genes of the regulatory proteins for blood coagulation and fibrinolysis.
Principal Investigator
AOKI Nobuo
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
thrombomodulinの理化学的生物学的諸性質ならびに病態生理学的意義
Principal Investigator
青木 延雄
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
# of Projects (Dsc)
# of Projects (Asc)
1.
AOKI Nobuo
(20048937)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
2.
MIURA Osamu
(10209710)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
3.
KATO Atsushi
(50183265)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
4.
三木 徹
(90242180)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
東田 修二
(80251510)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
6.
鈴木 謙
(90251511)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
大橋 一輝
(90262188)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
鎌田 七男
(00034629)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
田中 耕三
(00304452)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
田中 公夫
(70116622)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
宮川 清
(40200133)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
阿部 達生
(60079746)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
森 茂郎
(30010424)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
瀬戸 加大
(80154665)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
大木 操
(00158792)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
三谷 絹子
(50251244)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
室橋 郁生
(90182146)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
宮坂 信之
(30157622)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
YAMAMOTO Koh
(00281717)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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