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HIROSAWA Shinsaku
広沢 信作
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Researcher Number
50143574
Affiliation (based on the past Project Information)
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2001: 医科歯科大, 助教授
2000: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教授
1998: Medical Department, Associate Professor, 医学部, 助教授
1991 – 1998: 東京医科歯科大学, 医学部, 講師
1993: Tokyo Medical & Dental Univ., Dept.of Medicine, Instructor, 医学部第一内科, 講師
1991: 東京医科歯科大学, 医学部, 助手
1986 – 1988: 東京医科歯科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
Hematology
Keywords
Principal Investigator
アルファ2プラスミンインヒビター / プロモーター / 変異蛋白 / 凝固・線溶 / トロンボモジュリン / 粗面小胞体 / アルファ2プラスミンインヒビタ- / プロモ-タ- / CATアソセイ / トランスフェクション
…
More
/ バンドシフトアッセイ / ゲルシフトアッセイ / 発現調節 / BCL6 gene / Trans cription factor / Zinc finger / 悪性リンパ腫 / 染色体転座 / 切断点 / 血管内皮細胞 / CATアッセイ / サイクリックAMP / BCL-6 / ルシフェラーゼ / リンパ腫 / オールトランスレチノイン酸 / レチノイド / 内皮細胞 / 欠損症 / 発現実験 / 線溶系 / プラスミン インヒビター / マンノーストリミング / プロテアソーム / グルコーストリミング / ユビキチン / 分泌障害 / プロテアーゼ / α2-プラスミンインヒビター / alpha_2-plasmin inhibitor / mutant protein / endoplasmic reticulum / impaired secretion
…
More
Except Principal Investigator
アルファ2プラスミンインヒビター / 遺伝子変異 / 先天性欠損症 / 細胞内輸送 / 分泌障害 / 細胞内輸送障害 / プロテインC / アルフア2プラスミンインヒビタ- / 変異遺伝子 / プロテインC欠損症 / アルフア2プラスミンインヒビタ-欠損症 / 転座関連遺伝子 / FISH / 慢性骨髄性白血病 / インターフェロン / HLA / WT1 / RAD54 / 造血器腫瘍 / 骨・軟部腫瘍 / FISH法 / AML1遺伝子 / EWS遺伝子 / MLL遺伝子 / BCL6遺伝子 / EVI-1遺伝子 / スロンボモデュリン / モノクロナル抗体 / スロンビン / 血液凝固の制御 / 血管内皮細胞 / 血管内凝固 / 失天性欠損症 / 欠損症 / α_2PIーOkinawa / alpha_2-plasmin inhibitor / Congenital Deficiency / Intracellular Transport / Gene Mutation / Impairement of Secretion / セリンプロテアーゼインヒビター / 遺伝子 / 染色体 / 遺伝子発現 / アルファ2プラスミンインヒビター欠損症 / 線維素溶解 / 転写調節 / 血栓溶解 / 遺伝子ファミリー / cDNA / Alpha 2 plasmin inhibitor / Chromosome / Gene / Congenital deficiency of alpha 2 plasmin inhibitor
Less
Research Projects
(
16
results)
Co-Researchers
(
19
People)
Project Start Year (Newest)
Project Start Year (Oldest)
変異蛋白質のプロテアゾーム分解における糖鎖のトリミングの役割
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
Study for proteases involved in degradation of mutant alpha_2-plasma inhibitor in a endoplasmic roticela.
Principal Investigator
Principal Investigator
HIROSAWA Shinsaku
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
B細胞リンパ腫に関与する遺伝子(BCL-6)の発癌への関与のメカニズムの研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
転座関連遺伝子によるがんの診断・病態研究
Principal Investigator
鎌田 七男
Project Period (FY)
1996 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Hiroshima University
粗面小胞体を用いたアルファ2プラスミンインヒビターの輸送障害のメカニズムの研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
血管内皮細胞におけるトロンボモジュリン遺伝子の発現制御の研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
B細胞リンパ腫に関与する遺伝子(BCL-5)の同定と発症メカニズムの研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
血管内皮細胞におけるトロンボモジュリン遺伝子の発現制御の研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
遺伝性凝固線溶系蛋白欠損症の発症機転としての変異蛋白の細胞内輸送障害
Principal Investigator
青木 延雄
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
アルファ2プラスミンインヒビター遺伝子のプロモーター領域の研究
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
遺伝性凝固線溶系蛋白欠損症の発症機転としての変異蛋白の細胞内輸送障害
Principal Investigator
AOKI Nobuo
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo Medical and Dental University
アルファ2プラスミンインヒビター遺伝子のプロモーター領域に結合する蛋白質の同定
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
アルファ2プラスミンインヒビタ-遺伝子の発現調節
Principal Investigator
Principal Investigator
広沢 信作
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
Intracellular transport of Mutant alpha_2-plasmin inhibitor
Principal Investigator
AOKI Nobuo
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
Studies on the genes of the regulatory proteins for blood coagulation and fibrinolysis.
Principal Investigator
AOKI Nobuo
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
thrombomodulinの理化学的生物学的諸性質ならびに病態生理学的意義
Principal Investigator
青木 延雄
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
Tokyo Medical and Dental University
# of Projects (Dsc)
# of Projects (Asc)
1.
AOKI Nobuo
(20048937)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
2.
MIURA Osamu
(10209710)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
3.
KATO Atsushi
(50183265)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
4.
三木 徹
(90242180)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
東田 修二
(80251510)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
6.
鈴木 謙
(90251511)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
大橋 一輝
(90262188)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
鎌田 七男
(00034629)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
田中 耕三
(00304452)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
田中 公夫
(70116622)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
宮川 清
(40200133)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
阿部 達生
(60079746)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
森 茂郎
(30010424)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
瀬戸 加大
(80154665)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
大木 操
(00158792)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
三谷 絹子
(50251244)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
室橋 郁生
(90182146)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
宮坂 信之
(30157622)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
YAMAMOTO Koh
(00281717)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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