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ITOH Yoshinori  伊藤 善規

ORCIDConnect your ORCID iD *help
Researcher Number 50159927
Other IDs
Affiliation (based on the past Project Information) *help 2012 – 2015: 岐阜大学, 医学(系)研究科(研究院), 教授
2014: 岐阜大学, 大学院医学系研究科, 教授
2012: 岐阜大学, 大学院・医学系研究科, 教授
2010 – 2011: 岐阜大学, 医学系研究科, 教授
2006 – 2008: Gifu University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 … More
2006: Gifu University, Graduates School of Medicine, Professor, 大学院医学系研究科, 教授
2005: 九州大学, 大学病院, 助教授
2002: Kyushu University Hospital, Associate Professor, 医学部附属病院, 助教授 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy
Except Principal Investigator
Applied pharmacology / 応用薬理学・医療系薬学 / Medical sociology / General pharmacology
Keywords
Principal Investigator
cyclic AMP / p53 / TNF-α / 臨床試験 / がん化学療法 / 抗がん剤 / ネクローシス / caspases / necrosis / apoptosis … More / renal toxicity / cisplatin / 活性酸素種 / サイクリックAMP / p38MAPキナーゼ / カスパーゼ / アポトーシス / 腎障害 / シスプラチン / 頭頸部癌 / 放射線化学療法 / トローチ製剤 / 製剤 / 安定性試験 / 含量均一性試験 / トローチ / ポラプレジンク / 造血幹細胞移植 / 口内炎 / 制吐対策 / フィルム製剤 / 服用感 / 外来がん化学療法 / 制吐率 / 高度催吐性リスク / 乳癌患者 / クロスオーバー試験 / 口腔内速溶解フィルム / 制吐薬 / デキサメタゾン / ATP / 静脈炎 / メシル酸ナファモスタット / 血管内皮細胞障害 / L-システイン / グリシン / アミノ酸 / 血管内皮細胞 / 血管障害 / メシル酸ガベキサート … More
Except Principal Investigator
Proteinase-activated receptor-2 / ヨード造影剤 / 腎障害 / prostacyclin / cyclic AMP / ceramide / apoptosis / nephrotoxicity / contrast media / プロスタサイクリン / サイクリックAMP / セラミド / アポトーシス / 造影剤 / Carbazochrome / Endothelial cell / Tryptase / Histamine / Mast cell / Pulmonary dysfunction / Radiographic contrast medium / 抗ヒスタミン薬 / proteinase-activated receptor-2 / カルバゾクロムスルホン酸 / 血管内皮細胞 / トリプターゼ / ヒスタミン / 肥満細胞 / 肺障害 / 医療専門職人材育成 / 知識データベース / 有害事象原因候補医薬品 / F-ARES / 自殺企図 / 抗うつ薬 / SSRI / ネットワーク分析 / コミュニティ分析 / 医薬品有害事象 / FAERS / 人材育成 / 医療専門職 / 医薬品適正使用 / データマイニング / ビッグデータ / データベース / 有害事象 / 医薬品 / 小胞体 / コレステロール / 細胞膜 / MAPキナーゼ / カルシウム / ミトコンドリア / ネクローシス / アムホテリシンB / 抗菌薬 Less
  • Research Projects

    (8 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (19 People)
  •  Clinical study evaluating the effect of a newly developed polaprezinc lozenge for prevention of chemotherapy-induced oral mucositisPrincipal Investigator

    • Principal Investigator
      Itoh Yoshinori
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Gifu University
  •  On Development of Assisting System for Appropriate Use of Drugs and Fostering of Advanced Clinical Human Resources

    • Principal Investigator
      KINOSADA Yasutomi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical sociology
    • Research Institution
      Gifu University
  •  Preclinical and clinical studies on the usefulness of a newly developed fast dissolving oral film containing dexamethasonePrincipal Investigator

    • Principal Investigator
      ITOH Yoshinori
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Gifu University
  •  The elucidation of the mechanisms underlying drug-induced vascular injury and its prophylaxisPrincipal Investigator

    • Principal Investigator
      ITOH Yoshinori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Gifu University
  •  The elucidation of the mechanisms underlying antimicrobial agents-induced nephrotoxicity

    • Principal Investigator
      OISHI Ryozo
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kyushu University
  •  Protective roles for cyclic AMP and its analogs against cisplatin-induced nephropathyPrincipal Investigator

    • Principal Investigator
      ITOH Yoshinori
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Gifu University
      Kyushu University
  •  The elucidation of the mechanisms underlying contrast media induced nephrotoxicity and its prophylaxis.

    • Principal Investigator
      OISHI Ryozo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      KYUSHU UNIVERCITY
  •  Involvements of NO and histamine in radiographic contrast medium-induced pulmonary dysfunction

    • Principal Investigator
      OISHI Ryozo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kyushu University

All 2016 2014 2013 2012 2011 2010 2009 2008 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] Preparation and clinical evaluation of a novel lozenge containing polaprezinc, a zinc-L-carnosine, for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy.2016

    • Author(s)
      Hayashi H, Kobayashi R, Suzuki A, Yamada Y, Ishida M, Syakui T, Kitagawa J, Hayasi H, Sugiyama T, Takeuchi H, Tsurumi H, Itoh Y.
    • Journal Title

      European Journal of Pharmaceutics and Biopharmaceutics

      Volume: submitted

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460208
  • [Journal Article] Effect of polaprezinc on oral mucositis, irradiation period, and time to discharge in patients with head and neck cancer.2016

    • Author(s)
      Suzuki A, Kobayashi R, Shakui T, Kubota Y, Fukita M, Kuze B, Aoki M, Sugiyama T, Mizuta K, Itoh Y.
    • Journal Title

      Head & Neck

      Volume: in press Issue: 9 Pages: 1387-1392

    • DOI

      10.1002/hed.24446

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460208
  • [Journal Article] Polaprezinc prevents oral mucositis in patients treated with high dose chemotherapy followed by hematopoietic stem cell transplantation2014

    • Author(s)
      Hayashi H, Kobayashi R, Suzuki A, Ishihara M, Nakamura N, Kitagawa J, Kanemura N, Kasahara S, Kitaichi K, Hara T, Tsurumi H, Moriwaki H, Itoh Y
    • Journal Title

      Anticancer Research

      Volume: 34 Pages: 7271-7277

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460208
  • [Journal Article] Development of fast dissolving oral film containing dexamethasone as an antiemetic medication: clinical usefulness2012

    • Author(s)
      Nishigaki M, Kawahara K, Nawa M, Futamura M, Nishimura M, Matsuura K, Kitaichi K, Kawaguchi Y, Tsukioka T, Yoshida K, Itoh Y
    • Journal Title

      Int J Pharm

      Volume: 424 Pages: 12-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Journal Article] Amphotericin B-Induced Renal Tubular Cell Injury is Mediated by Na^+ Influx through Ion-Permeable Pores and Subsequent Activation of MAP Kinases and Elevation of Intracellular Ca^<2+>2009

    • Author(s)
      Yano T, Itoh Y, Kawamura E, Maeda A, Egashira N, Nishida M, Kurose H, Oishi R
    • Journal Title

      Antimicrob Agents Chemother 53

      Pages: 1420-1426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590252
  • [Journal Article] Characteristics of gabexate mesilate-induced cell injury in porcine aorta endothelial cells2008

    • Author(s)
      Aki T, Egashira N, Hama M, Yamauchi Y, Yano T , Itoh Y , Oishi R
    • Journal Title

      J Pharmacol Sci 106

      Pages: 415-422

    • NAID

      10024319114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590146
  • [Journal Article] Characteristics of gabexate mesilate-induced cell injury in porcine aorta endothelial cells2008

    • Author(s)
      Aki T, Egashira N, Hama M, Yamauchi Y, Yano T, Itoh Y, Oishi R
    • Journal Title

      Journal of Pharmacological Sciences 106

      Pages: 415-422

    • NAID

      10024319114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590146
  • [Journal Article] Protective effects of amino acids against gabexate mesilate-induced cell injury in porcine aorta endothelial cells2008

    • Author(s)
      Aki T, Egashira N, Yamauchi Y, Hama M, Yano T, Itoh Y, Yamada T, Oishi R
    • Journal Title

      J Pharmacol Sci 107

      Pages: 238-245

    • NAID

      10024321189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590146
  • [Journal Article] Protective effect of cyclic AMP against cisplatin-induced nephrotoxicity2006

    • Author(s)
      Mishima K., Baba A, Matsuo M., Itoh Y, Oishi R.
    • Journal Title

      Free Radical Biology & Medicine 40-9

      Pages: 1564-1577

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590129
  • [Journal Article] Protective effect of cyclic AMP against cisplatin-induced nephrotoxicity2006

    • Author(s)
      Mishima K., Baba A., Matsuo M., Itoh Y., Oishi R.
    • Journal Title

      Free Radical Biology & Medicine 40・9

      Pages: 1564-1577

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590129
  • [Journal Article] Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury.2006

    • Author(s)
      Itoh, Y. et al.
    • Journal Title

      Kidney Int. 69・2

      Pages: 288-297

    • Data Source
      KAKENHI-PROJECT-17590471
  • [Journal Article] Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury.2006

    • Author(s)
      Itoh Y, Yano T, Sendo T, Sueyasu M, Hirano K, Kanaide H, Oishi R.
    • Journal Title

      Kidney Internaional 69

      Pages: 288-297

    • Data Source
      KAKENHI-PROJECT-17590471
  • [Journal Article] Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury.2006

    • Author(s)
      Itoh Y, Yano T, Sendo T, Sueyasu M, Hirano K, Kanaide H, Oishi R
    • Journal Title

      Kidney International 69

      Pages: 288-297

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590471
  • [Journal Article] Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury.2006

    • Author(s)
      Itoh Y, Yano T, Sendo T, Sueyasu M, Hirano K, Kanaide H, Oishi R.
    • Journal Title

      Kidney International 69

      Pages: 288-297

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590471
  • [Journal Article] Clinical and experimental evidence for prevention of acute renal failure induced by radiographic contrast media.2005

    • Author(s)
      Itoh Y, Yano T, Sendo T, Oishi R.
    • Journal Title

      Journal of Pharmacological Sciences 97

      Pages: 473-488

    • NAID

      10025727305

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590471
  • [Journal Article] A prostacyclin analog prevents radiocontrast nephropathy via phosphorylation of cyclic AMP response element binding protein.2005

    • Author(s)
      Yano T, Itoh Y, Kubota T, Sendo T, Koyama T, Fujita T, Saeki K, Yuo A, Oishi R.
    • Journal Title

      American Journal of Pathology 166

      Pages: 1333-1342

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590471
  • [Journal Article] A prostacyclin analog prevents radiocontrast nephropathy via phosphorylation of cyclic AMP response element binding protein.2005

    • Author(s)
      Yano T, Itoh Y, Kubota T, Sendo T, Koyama T, Fujita T, Saeki K, Yuo A, Oishi R
    • Journal Title

      American Journal of Pathology 166

      Pages: 1333-1342

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590471
  • [Journal Article] Clinical and experimental evidence for prevention of acute renal failure induced by radiographic contrast media.2005

    • Author(s)
      Itoh Y, Yano T, Sendo T, Oishi R
    • Journal Title

      Journal of Pharmacological Sciences 97

      Pages: 473-488

    • NAID

      10025727305

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590471
  • [Presentation] 造血幹細胞移植前化学療法に伴う口内炎に対するポラプレジンクの予防効果2013

    • Author(s)
      林寛子、石原正志、兼村信宏、笠原千嗣、北市清幸、原武志、鶴見寿、森脇久隆、伊藤善規
    • Organizer
      第23回日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2013
    • Place of Presentation
      鈴鹿
    • Data Source
      KAKENHI-PROJECT-25460208
  • [Presentation] 造血幹細胞移植前化学療法に伴う口内炎に対するポラプレジンクの予防効果2013

    • Author(s)
      林寛子、石原正志、兼村信宏、笠原千嗣 、北市清幸、原武、鶴見寿、森脇久隆、伊藤善規
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25460208
  • [Presentation] シンポジウムテーマ:次世代型経口製剤に求められる臨床的機能性.「口腔内速溶解フィルムに潜在する製剤開発のシーズ」2012

    • Author(s)
      伊藤善規
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌(招待講演)
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] 口腔内速溶解フィルムに潜在する製剤開発のシーズ.シンポジウム「次世代型経口製剤に求められる臨床的機能性」2012

    • Author(s)
      伊藤善規
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] 遅発性悪心・嘔吐に対する新規開発デキサメタゾン含有口腔内速溶解フィルム製剤の有用性に関する研究2012

    • Author(s)
      西垣美奈子、森光華澄、名和正人、二村学、川口順敬、吉田和弘、(伊藤善規)
    • Organizer
      第20回日本乳癌学会
    • Place of Presentation
      熊本
    • Year and Date
      2012-07-15
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] 高用量 DEX 含有口腔内速溶解フィルムの開発と臨床応用.シンポジウム「病院薬剤師によるドラッグ・リプロファイリング」2011

    • Author(s)
      伊藤善規
    • Organizer
      医療薬学フォーラム 2011 クリニカルファーマシーシンポジウム
    • Place of Presentation
      旭川
    • Year and Date
      2011-07-09
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] 乳癌患者を対象とした遅発性悪心・嘔吐に対するデキサメタゾン含有口腔内速溶解フィルム製剤の有用性に関する研究2011

    • Author(s)
      河原加奈、西垣美奈子、西村美佐夫、飯原大稔、松浦克彦、川口順敬、吉田和弘、伊藤善規.
    • Organizer
      医療薬学フォーラム2011 クリニカルファーマシーシンポジウム
    • Place of Presentation
      旭川
    • Year and Date
      2011-07-15
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] シンポジウムテーマ:次世代型経口製剤に求められる臨床的機能性.「口腔内速溶解フィルムに潜在する製剤開発のシーズ」2011

    • Author(s)
      伊藤善規
    • Organizer
      医療薬学フォーラム2011クリニカルファーマシーシンポジウム
    • Place of Presentation
      旭川(招待講演)
    • Year and Date
      2011-07-09
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] 乳癌患者を対象としたデキサメタゾン含有口腔内速溶解フィルムの制吐薬としての有用性に関する研究2011

    • Author(s)
      西垣美奈子、河原加奈、西村美佐夫、渡辺千尋、飯原大稔、松浦克彦、川口順敬、吉田和弘、伊藤善規
    • Organizer
      日本薬学会第131 年会
    • Place of Presentation
      静岡-中止
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] がん化学療法における制吐対策を目的とした高用量デキサメタゾン含有フィルム製剤の開発.2010

    • Author(s)
      下田浩欣、松浦克彦、西村美佐夫、月岡忠夫、伊藤善規.
    • Organizer
      PLCM(耕薬)研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-01-28
    • Data Source
      KAKENHI-PROJECT-22590134
  • [Presentation] アムホテリシンBによる腎尿細管細胞障害におけるAPK 活性化ならびにミトコンドリア脱分極の関与2008

    • Author(s)
      前田朱香, 矢野貴久, 河村瑛子, 西田基宏, 江頭伸昭, 伊藤善規, 黒瀬等, 大石了三
    • Organizer
      第61回日本薬理学会西南部会
    • Place of Presentation
      鳥取
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-19590252
  • [Presentation] メシル酸ガベキサートによる血管内皮細胞障害の特性及びアミノ酸の保護作用に関する検討2008

    • Author(s)
      山内結衣, 安藝智子, 江頭伸昭, 矢野貴久, 伊藤善規, 大石了三
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-19590146
  • [Presentation] 耳鼻科病棟における病棟薬剤業務の取り組みと評価‐ 2. 放射線化学線療法における口内炎予防の取り組みが入院期間と医療費経済効果へ及ぼす影響

    • Author(s)
      木田有香,小林亮,鈴木昭夫,杉山正,伊藤善規
    • Organizer
      医療薬学フォーラム2014/第22回クリニカルファーマシーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-06-28 – 2014-06-29
    • Data Source
      KAKENHI-PROJECT-25460208
  • [Presentation] 耳鼻科病棟における病棟薬剤業務の取り組みと評価‐1.有害事象に対する治療効果が入院期間と医療経済効果へ及ぼす影響

    • Author(s)
      小林亮,鈴木昭夫,飯原大稔,岡安伸二,伊藤善規
    • Organizer
      医療薬学フォーラム2014/第22回クリニカルファーマシーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-06-28 – 2014-06-29
    • Data Source
      KAKENHI-PROJECT-25460208
  • 1.  OISHI Ryozo (90112325)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 15 results
  • 2.  EGASHIRA Nobuaki (80352269)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 3.  KINOSADA Yasutomi (50161526)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  NAKAMURA Mitsuhiro (30433204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KATAOKA Yasufumi (70136513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  HONDA Hiroshi (90145433)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  NIWA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TAKAI Mizuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TOHORI Kyouhei
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NISHIMURA Naoto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  FUKUDA Hirotsugu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MAEDA Takahide
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MATSUDA Yu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SUMINO Akikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KOJINA Soshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  GOMI Yousuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ARUUISU Naziru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  ABE Junko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  UMETSU Ryogo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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