OKAMOTO Shinichiro 岡本真一郎

… Alternative Names

岡本真一郎オカモトシンイチロウ

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Researcher Number	50160718
Other IDs
Affiliation (based on the past Project Information) *help	2012 – 2013: 慶應義塾大学, 医学部, 教授 2002 – 2003: 慶應義塾大学, 医学部, 助教授 1998 – 1999: 慶應義塾大学, 医学部, 専任講師 1993: 慶応大学, 医学部・内科, 講師 1992: 東京大学, 医科学研究所, 助手
Review Section/Research Field	Except Principal Investigator Hematology / Hematology
Keywords	Except Principal Investigator GVL / マイナー組織適合抗原 / 白血病 / T細胞 / 骨髄移植 / Graft versus host disease / Graft versus leukemia effect / single nucleotide polymorphism / hematopoietic stem cell transplantation / minor histocompatibility antigen … More / HLA / SNP / GVHD / 同種造血肝細胞移植 / 抗原特異的T細胞 / マイナー組織適合抗原(minor histocompatible antigen) / 一塩基多型(single nucleotide polymorphism) / 移植片対宿主病 / 移植片対白血病効果 / 同種造血幹細胞移植 / 5q- 症候群 / 血球分化 / 造血幹細胞 / ATOX1 / 骨髄異形成症候群 / 5q-症候群 / GVH / cDNA発現クローニング / 免疫療法 / GVL(graft versus leukemia) / GVHD(graft versus host disease) / 同種骨髄移植 / マイナー組織 / 遺伝子診断 / 温度勾配電気泳動 / PCR / TCR(T細胞抗原受容体) / トランス再構成 / 染色体異常 / 免疫不全 / 抗原受容体遺伝子 Less

A role for ATOX1 in 5q- syndrome
- Principal Investigator
  
  NAKAJIMA Hideaki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Keio University
Identification of minor histacompatibility antigens associated with graft uersus leukemia effect.
- Principal Investigator
  
  SUMIMOTO Hidetoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KEIO UNIVERSITY
移植片対宿主病(GVHD)に関わるマイナー組織適合抗原の同定
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Keio University
骨髄移植後に出現するT細胞分画のPCRと温度勾配ゲル電気泳動法によるクローン解析
- Principal Investigator
  
  小林幸夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
抗原受容体遺伝子のトランス再構成に対する免疫不全状態の影響とその病態生理学的意義
- Principal Investigator
  
  小林幸夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

All 2014 2013 2012

All Journal Article Presentation

[Journal Article] Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients2014
- Author(s)
  Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Yuasa S, Yamazaki S, Nishimura T, Sadahira K, Fukuda K, Okano H, Nakauchi H, Morita Y, Matsumura I, Kudo K, Ito E, Ebihara Y, Tsuji K, Harada Y, Harada H, Okamoto S, Nakajima H
- Journal Title
  
  Leukemia
  
  Volume: 28 Issue: 12 Pages: 2344-54
- DOI
  10.1038/leu.2014.136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390272, KAKENHI-PROJECT-24591398, KAKENHI-PROJECT-24659467, KAKENHI-PUBLICLY-25118716, KAKENHI-PUBLICLY-25130712, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-25461439, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-26257501, KAKENHI-PROJECT-26293243, KAKENHI-PROJECT-26670511
[Journal Article] Tet2-mutated myeloid progenitors possess aberrant in vitro self-renewal capacity2014
- Author(s)
  Kunimoto H, Fukuchi Y, Sakurai M, Takubo K, Okamoto S, Nakajima H.
- Journal Title
  
  Blood
  
  Volume: 123 Pages: 2897-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659467
[Journal Article] Direct reprogramming of terminally differentiated B cells into erythroid lineage2012
- Author(s)
  Sadahira K, Fukuchi Y, Kunimono H, Sakurai M, Ikeda Y, Okamoto S, Nakajima H.
- Journal Title
  
  FEBS Letters
  
  Volume: 586 Pages: 3645-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659467
[Journal Article] Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells2012
- Author(s)
  Kunimoto H, Fukuchi Y, Sakurai M, Sadahira K, Ikeda Y, Okamoto S, Nakajima H.
- Journal Title
  
  Scientific Reports
  
  Volume: 2 Pages: 273-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659467
[Journal Article] Robo4 plays a role in bone marrow homing and mobilization, but is not essential in the long-term repopulating capacity of hematopoietic stem cells2012
- Author(s)
  Goto-Koshino Y, Fukuchi Y, Shibata F, Abe D, Kuroda K, Okamoto S, Kitamura T, Nakajima H.
- Journal Title
  
  PLOS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659467
[Presentation] Impaired emergence of hematopoietic progenitors and defective megakaryocyte differentiation from FPD/AML-derived induced pluripotent stem cells2013
- Author(s)
  Masatoshi Sakurai, Hiroyoshi Kunimoto, Naohide Watanabe, Yumi Fukuchi, Shinsuke Yuasa, Keiichi Fukuda, Satoshi Yamazaki, Hiromitsu Nakauchi, Yasuhiro Ebihara, Koichiro Tsuji, Etsuro Ito, Yuka Harada, Hironori Harada, Shinichiro Okamoto, Hideaki Nakajima
- Organizer
  EMBO Workshop-RUNX transcription factors in development and disease
- Place of Presentation
  ドイツ、Wilsede
- Year and Date
  2013-06-17
- Data Source
  KAKENHI-PROJECT-24659467
[Presentation] Chemo-Immunotherapy With Hyper-CVAD/MA and Rituximab For B-Cell Lymphomas Leads To Prolonged Immune Suppression Compared To Conventional Treatment With R-CHOP2013
- Author(s)
  Eri Matsuki, Taku Kikuchi, Norisato Hashimoto, Shunsuke Souma, Sumiko Kohashi, Takaaki Toyama, Masatoshi Sakurai, Daiki Karigane, Daichi Abe, Takayuki Shimizu, Kenji Yokoyama, Hideaki Nakajima, Shinichiro Okamoto
- Organizer
  55th Annual Meeting of American Society of Hematology, Simultaneous Session
- Place of Presentation
  米国、ニューオーリンズ
- Year and Date
  2013-12-09
- Data Source
  KAKENHI-PROJECT-24659467
[Presentation] Impaired hematopoietic differentiation of iPSCs derived from patients with FPD/AML2012
- Author(s)
  Masatoshi Sakurai, Hiroyoshi Kunimoto, Naohide Watanabe, Yumi Fukuchi, Ken Sadahira, Shinsuke Yuasa, Keiichi Fukuda, Satoshi Yamazaki, Hiromitsu Nakauchi, Yasuhiro Ebihara, Koichiro Tsuji, Etsuro Ito, Yuka Harada, Hironori Harada, Shinichiro Okamoto, Hideaki Nakajima
- Organizer
  54th Annual Meeting of American Society of Hematology, Simultaneous Session
- Place of Presentation
  米国、アトランタ
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-24659467
[Presentation] Tet2 Uniquely Regulates Self-Renewal and Long Term Repopulating Capacity of Fetal Liver and Bone Marrow Hematopoietic Stem Cells2012
- Author(s)
  Hiroyoshi Kunimoto, Yumi Fukuchi, Masatoshi Sakurai, Daichi Abe, Ken Sadahira, Yasuo Ikeda, Shinichiro Okamoto, Hideaki Nakajima
- Organizer
  54th Annual Meeting of American Society of Hematology, Simultaneous Session
- Place of Presentation
  米国、アトランタ
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-24659467
[Presentation] Disruption of Tet2 leads to enhanced self-renewal and competitive repopulating capacity of fetal liver hematopoietic stem cells2012
- Author(s)
  Hiroyoshi Kunimoto, Yumi Fukuchi , Masatoshi Sakurai, Ken Sadahira, Yasuo Ikeda, Shinichiro Okamoto, Hideaki Nakajima
- Organizer
  10^<th> Annual Meeting of International Society of Stem Cell Research
- Place of Presentation
  横浜
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-24659467
[Presentation] Reprogramming of mature B cells into erythroid lineage2012
- Author(s)
  Ken Sadahira, Yumi Fukuchi, Hiroyoshi Kunimoto, Masatoshi Sakurai, Shinichiro Okamoto, Hideaki Nakajima
- Organizer
  10^<th> Annual Meeting of International Society of Stem Cell Research
- Place of Presentation
  横浜
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-24659467

1. KAWAKAMI Yutaka (50161287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. IKEDA Yasuo (00110883)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 小林幸夫 (50240734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 小澤敬也 (30137707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 浅野茂隆 (50134614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAJIMA Hideaki (30217723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. SUMIMOTO Hidetoshi (00306838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FUJITA Tomonobu (20199334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 池田英之 (40301494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HARADA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 原田浩徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKAMOTO Shinichiro 岡本 真一郎

岡本 真一郎 オカモト シンイチロウ

Research Projects

Research Products

Co-Researchers

A role for ATOX1 in 5q- syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of minor histacompatibility antigens associated with graft uersus leukemia effect.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

移植片対宿主病(GVHD)に関わるマイナー組織適合抗原の同定

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨髄移植後に出現するT細胞分画のPCRと温度勾配ゲル電気泳動法によるクローン解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗原受容体遺伝子のトランス再構成に対する免疫不全状態の影響とその病態生理学的意義

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tet2-mutated myeloid progenitors possess aberrant in vitro self-renewal capacity2014

Author(s)

Journal Title

Data Source

[Journal Article] Direct reprogramming of terminally differentiated B cells into erythroid lineage2012

Author(s)

Journal Title

Data Source

[Journal Article] Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells2012

Author(s)

Journal Title

Data Source

[Journal Article] Robo4 plays a role in bone marrow homing and mobilization, but is not essential in the long-term repopulating capacity of hematopoietic stem cells2012

Author(s)

Journal Title

Data Source

[Presentation] Impaired emergence of hematopoietic progenitors and defective megakaryocyte differentiation from FPD/AML-derived induced pluripotent stem cells2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Chemo-Immunotherapy With Hyper-CVAD/MA and Rituximab For B-Cell Lymphomas Leads To Prolonged Immune Suppression Compared To Conventional Treatment With R-CHOP2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Impaired hematopoietic differentiation of iPSCs derived from patients with FPD/AML2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Tet2 Uniquely Regulates Self-Renewal and Long Term Repopulating Capacity of Fetal Liver and Bone Marrow Hematopoietic Stem Cells2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

OKAMOTO Shinichiro 岡本真一郎

岡本真一郎オカモトシンイチロウ