Hiratsuka Hiroyoshi 平塚博義

… Alternative Names

平塚博義ヒラツカヒロヨシ

HIRATSUKA Hiroyoshi 平塚博義

HIRATSUKA Hiroyosi 平塚博義

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Researcher Number	50165180
Other IDs
External Links
Affiliation (Current)	2025: 札幌医科大学, 医学部, 名誉教授
Affiliation (based on the past Project Information) *help	2016 – 2017: 札幌医科大学, 医学部, 教授 2004 – 2014: 札幌医科大学, 医学部, 教授 1997 – 2000: School of Medicine, University of the Ryukyus Assoc.Prof., 医学部, 助教授 1991 – 1996: 札幌医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Surgical dentistry / Surgical dentistry / 外科・放射線系歯学 Except Principal Investigator Surgical dentistry / Surgical dentistry / 外科・放射線系歯学
Keywords	Principal Investigator 口腔癌 / 口腔扁平上皮癌 / 頚部リンパ節転移 / 口腔がん / 腫瘍微小環境 / tumor budding / 癌微小環境 / Tumor Budding / dentistry / Wnt signaling pathway … More / genomics / cancer / Wntシグナル / DNAチル化 / SFRP遺伝子 / 歯学 / シグナル伝達 / ゲノム / 癌 / Combined Evaluation / E-Cadherin-Catenin Family / Lymph Node Metastasis / Tongue Cancer / 複合診断 / 画像診断 / 遺伝子異常 / Eカドヘリンーカテニンファミリー / Eカドヘリン-カテニンファミリー / 舌癌 / Probability / Cervical Lymph Node Metastasis / Oral Cancer / 細胞増殖活性 / カドヘリン-カテニン複合体 / 接着分子 / 悪性度 / US,CT画像 / 診断 / 頸部リンパ節転移 / α-カテニン / E-カドヘリン / 幹細胞 / ワクチン / ALDH1 / がんワクチン / がん幹細胞 / HIF-1 / がん発育先進部 / 化学療法 / EMT / NF-κB/p65 / GLUT-1 / 上皮-間葉転換 / 低酸素 / βカテニン / 同種殺細胞効果 / Tリンパ球浸潤 / ラミニン / 口腔粘膜癌 / 間質コラーゲン / DNAパターン / 効果発現因子 / 免疫化学療法 … More Except Principal Investigator 遺伝子 / 口腔癌 / 癌 / nm23 / p53 / チェックポイント / ユビキチンリガーゼ / 薬剤感受性 / 細胞周期 / トランスレーショナルリサーチ / 歯学 / Apoptosis / 口腔扁平上皮癌 / アポトーシス / 癌抑制遺伝子 / 悪性度 / エピジェネティクス / 臨床腫瘍学 / ゲノム / 微小管阻害剤 / E型カドヘリン / 口腔粘膜癌 / translationalresearch / checkpoint / ubiquitinliease / cell cycle / microtubule inhibitor / drug sensitivity / トランスレーショナルリサーチ / Ubiquitin ligase / Cell Cycle Control / Chemosensitivity / Translational Research / Cancer / 感受性診断 / 微小管脱重合阻害剤 / 有糸分裂 / 細胞周期制御 / 臨床 / がん / Banking / Gene analysis / Cleft palate / Cleft lip / Congenital anomaly / 口唇口蓋裂 / バンキング / 遺伝子解析 / 口蓋裂 / 口唇裂 / 先天異常 / Nuclear DNA contents / Oral squamous cell carcinoma / コラーゲン / カドヘリン / P53 / typeI IIコラーゲン / 超4C率 / 細胞核DNA量 / 核DNA量 / Malignant behavior / Survival / Clinocopathological factor / Cell proliferation / Oncogene protein / TUNEL / Oral cancer / 分子病理学 / 核内増殖因子MIB-1 / 癌抑制遺伝子産物p53 / 癌の悪性度 / cyclin D1 / bcl-2 / MIB-1 / Nick end-labeling / 生存率 / 臨床病理学的因子 / 細胞増殖 / TUNEL法 / tumor marker / oncogene / biological behavior / E-cadherin / mutation / oral cancer / 予後 / 生物学的悪性度 / NDP Kinase / NM23 / P-53 / 癌転移抑制遺伝子 / 癌遺伝子 / 突然変異 / E-カドヘリン / 腫瘍マーカー / シグナル伝達 / トランスレーションリサーチ / PARP-1 / PARP-1阻害剤 / CHFR / 細胞接着分子 / 免疫組織学的研究 / ICAM-1 / LFA-1 / I型コラーゲン / 頸部リンパ節転移 / 間質反応 / 基底膜 / 増殖期細胞 / 抗癌剤感受性 / 悪性度別治療法 / 組織学的悪性度 / 潜在性頸部リンパ節転移 / 治療法 / 治療方針 / 頚部リンパ節転移 / 悪性度評価 Less

The elucidation of tumor microenvironment in invasive front of oral cancer and its application to therapyPrincipal Investigator
- Principal Investigator
  
  Hiratsuka Hiroyoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Development of a novel cancer vaccine that targets oral cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  HIRATSUKA Hiroyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Expression analysis of DKK gene and development of a molecular targeted therapy for oral cancer
- Principal Investigator
  
  SOGABE Yohei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Analysis of the β catenin gene abnormality and therapeutic application for oral cancer.Principal Investigator
- Principal Investigator
  
  HIRATSUKA Hiroyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Expression analysis of SFRP family genes for development of molecular targeted therapy for oral cancer
- Principal Investigator
  
  SOGABE Yohei
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Functional analysis of CHFR: Diagnostic and therapeutic application for oral squamous cell cancer
- Principal Investigator
  
  TOKINO Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Diagnostic and therapeutic application of cell-cycle checkpoint genes for oral squamous cell cancer.
- Principal Investigator
  
  TOKINO Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
EVALUATION OF GRADE OF MALIGNANCY AND ITS CLINICAL USE ON THE BASIS OF SFRP METHYLATION IN ORAL SQUAMOUS CELL CARCINOMAPrincipal Investigator
- Principal Investigator
  
  HIRATSUKA Hiroyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Study concerning analysis of genes causing oral congenital anomalies
- Principal Investigator
  
  NATSUME Nagato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Gakuin University
Diagnostic and therapeutic application of checkpoint gene CHFR in oral squamous cell cancer.
- Principal Investigator
  
  TOKINO Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Combined evaluation of lymph node metastasis in squamous cell carcinoma of the oral cavityPrincipal Investigator
- Principal Investigator
  
  HIRATSUKA Hiroyoshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Surgical dentistry
- Research Institution
  UNIVERSITY OF THE RYUKYUS, SCHOOL OF MEDICINE
口腔粘膜癌の頸部リンパ節転移に関する細胞接着分子の免疫組織学的研究
- Principal Investigator
  
  関口隆
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Diagnosis and treatment of cervical lymph node metastasis based on expression of cadherin-catenin complexPrincipal Investigator
- Principal Investigator
  
  HIRATSUAKA Hiroyoshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  University of the Ryukyus
  Sapporo Medical University
Development of treatment modality for oral squamous carcinoma based on histological, malignancy and biologic beharior
- Principal Investigator
  
  KOHAMA Gen-iku
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Department of Oral Surgery, Sapporo Medical University School of Medicine
Evaluations of apoptosis-relating factors as tumor markers with special reference to diagnosis and treatment in oral cancers
- Principal Investigator
  
  ODAJIMA Tetsuyo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
口腔癌に対する免疫化学法の効果発現に関する基礎的ならびに臨床的研究Principal Investigator
- Principal Investigator
  
  平塚博義
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  Sapporo Medical University
Oncogenes and tumor markers in oral squamous cell carcinomas with special reference to clinicopathological features
- Principal Investigator
  
  ODAJIMA Tetsuyo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  Sapporo Medical University
口腔癌の悪性度別治療法の開発に関する臨床病理,免疫学的研究
- Principal Investigator
  
  KOHAMA Gen-iku
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  Sapporo Medical University

All 2018 2013 2012 2011 2010 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] Anatomy, Kinematics and Diseases2012
- Author(s)
  Nakamori K, Dehari H, Miyazaki A, Ogi K, Anbo N, Shimanishi M, Kaneko T, Hiratsuka H
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-22390388
[Book] よくわかる歯科医学・口腔ケア2011
- Author(s)
  平塚博義
- Total Pages
  124
- Publisher
  医学情報社
- Data Source
  KAKENHI-PROJECT-22390388
[Journal Article] Tumor budding is an independent prognostic marker in early stage oral squamous cell carcinoma: With special reference to the mode of invasion and worst pattern of invasion2018
- Author(s)
  清水翔太, 宮﨑晃亘, 園田智子, 小池和茂, 荻　和弘, 小林淳一, 金子　剛, 五十嵐友彦, 上田　愛, 出張裕也, 宮川　明, 長谷川匡, 平塚博義
- Journal Title
  
  PLOS ONE
  
  Volume: 13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15827
[Journal Article] Highexpression of ALDH1 and SOX2 diffuse staining pattern of oral squamous cellcarcinomas correlates to lymph node metastasis.2013
- Author(s)
  Michifuri Y, Hirohashi Y, Torigoe T,Miyazaki A, Kobayashi J, Sasaki T, FujinoJ, Asanuma H, Tamura Y, Nakamori K, Hasegawa T, Hiratsuka H, Sato N.
- Journal Title
  
  Pathol Int.
  
  Volume: 62(10) Issue: 10 Pages: 684-9
- DOI
  10.1111/j.1440-1827.2012.02851.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-22592242, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659901, KAKENHI-PROJECT-24792005
[Journal Article] Silencing of GLUT-1 inhibits sensitization of oral cancer cells to cisplatin during hypoxia.2013
- Author(s)
  Shimanishi M, Ogi K, Sogabe Y, Kaneko T, Dehari H, Miyazaki A, Hiratsuka H.
- Journal Title
  
  J Oral Pathol Med.
  
  Volume: 42(5) Issue: 5 Pages: 382-8
- DOI
  10.1111/jop.12028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-24659901
[Journal Article] Suppression of NF-κB/p65 inhibits the proliferation in oral squamous cancer cells.2013
- Author(s)
  Naoki Anbo, Kazuhiro Ogi, Yohei Sogabe, Makoto Shimanishi, Takeshi Kaneko, Hironari Dehari, Akihiro Miyazaki, Hiroyoshi Hiratsuka.
- Journal Title
  
  Journal of Cancer Therapy
  
  Volume: 04 Issue: 04 Pages: 891-897
- DOI
  10.4236/jct.2013.44100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390388
[Journal Article] Six-transmembrane epithelial antigen of the prostate-1 plays a role for in vivo tumor growth via intercellular communication2013
- Author(s)
  Yamamoto T, Tamura Y, Kobayashi J, Kamiguchi K, Hirohashi Y, Miyazaki A, Torigoe T, Asanuma H, Hiratsuka H, Sato N
- Journal Title
  
  Exp. Cell Res.
  
  Volume: 319 Issue: 17 Pages: 2617-29
- DOI
  10.1016/j.yexcr.2013.07.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659901
[Journal Article] Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.2013
- Author(s)
  Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 439 Issue: 1 Pages: 96-102
- DOI
  10.1016/j.bbrc.2013.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659901, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-24792005, KAKENHI-PROJECT-25462344, KAKENHI-PROJECT-25463115
[Journal Article] Granulocyte colony-stimulating factor-producing squamous cellcarcinoma of the lower gingiva: a case report.2012
- Author(s)
  Kobayashi J, Miyazaki A, Yamamot T, Nakamori K, Suzuki R, Kaneko T, Suzuki N, Hiratsuka H.
- Journal Title
  
  Head Neck Oncol.
  
  Volume: 4 Issue: 1 Pages: 35-35
- DOI
  10.1186/1758-3284-4-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-24659901
[Journal Article] 口腔悪性腫瘍.2012
- Author(s)
  宮崎晃亘, 平塚博義.
- Journal Title
  
  医学と薬学
  
  Volume: 67 Pages: 799-805
- Data Source
  KAKENHI-PROJECT-22390388
[Journal Article] Phase I clinical trial of survivin-derived peptide vaccine therapy for patients with advanced or recurrent oral cancer2011
- Author(s)
  Miyazaki A, Kobayashi J, Torigoe T, Hirohashi Y, Yamamoto T, Yamaguchi A, Asanuma H, Takahashi A, Michifuri Y, Nakamori K, Nagai I, Sato N, Hiratsuka H.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 2 Pages: 324-329
- DOI
  10.1111/j.1349-7006.2010.01789.x
- NAID
  10029289826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-22592242, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235
[Journal Article] Cytoplasmic RASSF2A is a pro-appoptotic mediator whose expression is epigenetically silenced in gastric cancer.2008
- Author(s)
  Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka H, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T
- Journal Title
  
  Carcinogenesis Vol.29, No.7
  
  Pages: 1312-1318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390519
[Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008
- Author(s)
  Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T
- Journal Title
  
  Cancer Sci Vol.99, No.5
  
  Pages: 958-966
- NAID
  10024006089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390519
[Journal Article] Cytoplasmic RASSF2A is a Pro-apoptotic mediator whose expression is epigenetically silenced in gastric cancer2008
- Author(s)
  Maruyama, R., Akino, K., Suzuki, H., Imai, T., Ohe-Toyota, M., Yamamoto, E., Nojima, M., Fujikane, T., Sasaki, Y., Yamashita, T., Watanabe, Y., Hiratsuka, H., Hirata, K., Itoh, F., Imai, K., Shinomura, Y., Tokino, T
- Journal Title
  
  Carcinogenesis (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Journal Article] Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma2008
- Author(s)
  Sogabe, Y., Suzuki, H., Toyota, M., Ogi, K., Imai, T., Nojima, M., Sasaki, Y., Hiratsuka, H., Tokino, T
- Journal Title
  
  Int J Oncol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Journal Article] Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.2008
- Author(s)
  Sogabe Y, Suzuki H, Toyata M, Ogi K, Imai T, Nojima M, Sasaki Y, Hiratsuka H, Tokino T
- Journal Title
  
  Int J Oncology Vol.32, No.6
  
  Pages: 1253-1261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390519
[Journal Article] A single-institute phase I/II trial combining nedaplatin dose escalation with a fixed dose of docetaxel for induction chemotherapy of oral squamous cell carcinoma2008
- Author(s)
  Miyazaki, A., Kobayashi, J., Yamatoto, T., Kido, Y., Takemura, K., Abe, M., Tomihara, K., Dehari, H., Nakamori, K., Nagai, I., Hiratsuka, H
- Journal Title
  
  Oral Oncol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma2008
- Author(s)
  Imai, T., Toyota, M., Suzuki, H., Akino, K., Ogi, K., Sogabe, Y., Kashima, L., Maruyama, R., Nojima, M., Mita, H., Sasaki, Y., Itoh, F., Imai, K., Shinomura, Y., Hiratsuka, H., Tokino, T
- Journal Title
  
  Cancer sci (in press)
- NAID
  10024006089
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Journal Article] PRDM5 identified as a target of epigtnetic silencing in colorectal and gastric cancer2007
- Author(s)
  Watanabe, Y., Toyota, M., Kondo, Y., Suzuki, H., Imai, T., Ohe-Toyota, M., Maruyama, R., Nojima, M., Sasaki, Y., Sekido, Y., Hiratsuka, H., Shinomura, Y., Imai, K., Itoh, F., Tokino, T
- Journal Title
  
  Clin Cancer Res 13(16)
  
  Pages: 4786-4794
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Journal Article] Gene transfer the CD-40-ligand to human dendritic cells ifichices NK-medjated antitumor effects against human carcinoma cells2007
- Author(s)
  Tomihara, K., Kato, K., Masuta, Y., Nakamura, K., Tanaka, T., Hiratsuka, H., Hamada, H
- Journal Title
  
  Int J Cancer 120(7)
  
  Pages: 1491-1498
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Journal Article] Efficient Cross-Presentation by Heat Shock Protein 90 Peptide Complex-Loaded Dendritic Cells via an Endosomal Pathway2007
- Author(s)
  Kurotaki, T., Tamura, Y., Ueda, G., Oura, J., Kutami, G., Hirohashi, Y., Sahara, H., Torigoe, T., Hiratsuka, H., Sunakawa, H., Hirata, K., Sato, N
- Journal Title
  
  J Immunol 179(3)
  
  Pages: 1803-1813
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Journal Article] Aberrant expression of β- and γ-catenin are independent prognostic markers in oral squamous cell carcinoma2006
- Author(s)
  Ueda, G., Sunakawa, H., Nakamori, K., Shinya, T., Tsuhako, W., Tamura, Y., Kosugi, T., Sato, N., Ogi, K., Hiratsuka, H
- Journal Title
  
  Int J Oral Maxillofac Surg 35(4)
  
  Pages: 356-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592223
[Presentation] Survivin-derived peptide vaccine therapy for patients with advanced or recurrent oral cancer - Phase I clinical trial2012
- Author(s)
  Akihiro Miyazaki, Junichi Kobayashi, Toshihiko Torigoe, Yoshihiko Hirohashi, Yoshitaka Michifuri, Takanori Sasaki, Junki Fujino, Hiroko Asanuma, Akari Takahashi, Noriyuki Sato, Hiroyoshi Hiratsuka.
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Silencing of GLUT1 inhibits sensitizes oral cancer cells to CDDP during hypoxia2012
- Author(s)
  Kazuhiro Ogi, Makoto Shimanishi, Takeshi Kaneko, Hironari Dehari, Akihiro Miyazaki, Hiroyoshi Hiratsuka.
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 小胞体ストレスによりMHCクラスI抗原プロセシングの分子機構と病態2011
- Author(s)
  佐々木敬則、金関貴幸、山本絵利、植田恵実理、田村保明、鳥越俊彦、平塚博義、佐藤昇志
- Organizer
  日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] A phase I study of survivin-2B peptide vaccine therapy in combination with interferon-α for patients with oral cancer.2011
- Author(s)
  Akihiro Miyazaki, Junichi Kobayashi, Toshihiko Torigoe, Yoshihiko Hirohashi, Yoshitaka Michifuri, Takanori Sasaki, Hiroko Asanuma, Noriyuki Sato, Hiroyoshi Hiratsuka
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 動注化学放射線療法により制御し得たルビエールリンパ節転移の一例2011
- Author(s)
  平塚博義, 他
- Organizer
  第37回日本口腔外科学会北日本地方会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Analysis of cDNA plate array between CDDP sensitive and CDDP resistant. Oral squamous cancer cell line ; HIF-1 can regulate NF-κB under hypoxia2011
- Author(s)
  Naoki Anbo, Makoto Shimanishi, Kazuhiro Ogi, Hiroyoshi Hiratsuka
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Identification of epigenetic change of genes that mediates hypoxic adaptation using HIF regulated cDNA plate array.2011
- Author(s)
  Kazuhiro Ogi, Makoto Shimanishi, Naoki Anbo, Tsuyoshi Kaneko, Yohei sogabe, Hironari Dahari, Hiroyoshi Hiratsuka
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 口腔がんにおけるがん幹細胞特異的分子の同定2011
- Author(s)
  道振義貴、廣橋良彦、鳥越俊彦、宮崎晃亘、小林淳一、田村保明、平塚博義、佐藤昇志
- Organizer
  日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] The cells under the ER stress present novel pMHCI and elicit CD8+ T cell responses2011
- Author(s)
  Takanori Sasaki, Takayuki Kaneseki, Emiri Nakazawa, Eri Saka, Yasuaki Tamura, Toshihiko Torigoe, Hiroyoshi Hiratsuka,Noriyuki Sato
- Organizer
  The 2011 CSSI Congress
- Place of Presentation
  カナダ、ケベック
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] The cells under the ER stress present novel pMHCI and elict CD8+T cell responses.2011
- Author(s)
  Takanori Sasaki, Takayuki Kanaseki, Hiroyoshi Hiratsuka, Noriyuki Sato
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Small proline-rich protein-1B (SPRP1B) is overexpressed in ALDEFLUOR bright human cancer stem-like oral squamous cell carcinoma and related to its maintenance.2011
- Author(s)
  Yoshitaka Michifuri, Yoshihiko Hirohashi, Toshihiko Torigoe, Akihiro Miyazaki, Junichi Kobayashi, Takashi Yamamoto, Yasuaki Tamura, Akari Takahashi, Kenji Nakamori, Akira Yamaguchi, Hiroyoshi Hiratsuka, Noriyuki Sato
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 口腔癌における癌低酸素領域での血管新生因子に関する臨床的意義2010
- Author(s)
  荻和弘、仲盛健治、宮崎晃亘、島西真琴、安保直樹、平塚博義
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Clinical Significance of Cortactin and Cyclin D1 Expression in Squamous Cell Carcinomas of the Tongue2010
- Author(s)
  Kenji Nakamori, Hironari Dehari, Takashi Imai, Akihiro Miyazaki, Kazuhiro Ogi, Naoki Anbo, Makoto Shimanishi, Hiroyoshi Hiratsuka
- Organizer
  20th European Association for Cranio-Maxillo-facial Surgery
- Place of Presentation
  ベルギー
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] 口腔癌に対するサバイビン2Bペプチドワクチン療法の第I臨床試験2010
- Author(s)
  宮崎晃亘、小林淳一、鳥越俊彦、廣橋良彦、山本崇、道振義貴、浅沼広子、荻和弘、山口晃、佐藤昇志、平塚博義
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] hMHL1, hMSH2の口腔扁平上皮癌の抗癌剤耐性獲得への関与に関する研究2010
- Author(s)
  安保直樹、島西真琴、荻和弘、平塚博義
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22390388
[Presentation] Immunotherapeutic benefit of α-interferon in survivin2B-derived peptide vaccination for patients with oral cancer.
- Author(s)
  Akihiro　Miyazaki,　Junichi Kobayashi, Toshihiko Torigoe, Yoshihiko Hirohashi, Takanori Sasaki, Sho Miyamoto, Kazuhiro Ogi, Hironari Dehari, Noriyuki Sato, Hiroyoshi Hiratsuka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Identification of long non-coding RNAs potentially involved in oral squamous cell carcinoma.
- Author(s)
  Koyo Nishiyama, Reo Maruyama, Kosuke Takeda, Takahumi Nakagaki, Takeshi Niinuma, Kazuhiro Ogi, Hironari Dehari, Akihiro Miyazaki, Masahiro Kai, Yasushi Sasaki, Takeshi Tokino, Hiromu Suzuki, Hiroyoshi Hiratsuka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Tumor cells exposed to microenvironmental stresses express non-classical MHC Ib that attenuates CD8+ T cell responses
- Author(s)
  Takanori Sasaki, Takayuki Kanaseki, Sachiyo Kawami, Eri Saka, Yasuaki Tamura, Toshihiko Torigoe, Hiroyoshi Hiratsuka, Noriyuki Sato
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 family target
- Author(s)
  Kousuke Takeda，Yasushi Sasaki , Takafumi Nakagaki, Miyuki Tamura, Masashi Idogawa , Kazuhiro Ogi, Hiroyoshi Hiratsuka, Takashi Tokino
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Wnt/β-catenin signaling pathway directly controls hypoxia induced epithelial mesenchymal transition in oral cancer
- Author(s)
  Takeshi Kaneko, Hironari Dehari, Kazuhiro Ogi, Kousuke Takeda, Junichi Kobayashi, Akihiro Miyazaki, Hiroyoshi Hiratsuka
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] Identification of the natural antigenic peptide derived from FAM83B that is specifically expressed in cancer stem cells.
- Author(s)
  Sho Miyamoto, Takayuki Kanaseki, Akari Takahashi, Kochin Vitaly, Yoshihiko Hirohashi, Toshihiko Torigoe, Hiroyoshi Hiratsuka, Noriyuki Sato
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] 口腔がんに対するサバイビン２Bペプチドワクチン・インターフェロン併用療法の臨床試験
- Author(s)
  宮崎晃亘、小林淳一、鳥越俊彦、廣橋良彦、佐々木敬則、宮本昇、出張裕也、荻和弘、佐藤昇志、平塚博義
- Organizer
  第５２回日本癌治療学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-24659901
[Presentation] A next-Generation Sequencing Screen for Mutational Hotspots in 50 Cancer-Related Genes using Semiconductor Sequencer.
- Author(s)
  Takafumi　Nakagaki, Yasushi Sasaki, Masashi Idogawa, Kousuke Takeda, Miyuki Tamura, Tomoko Ohashi, Kazuhiro Ogi, Hiroyoshi Hiratsuka, Takashi Tokino
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24659901

1. OGI Kazuhiro (40433114)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. TOKINO Takashi (40202197)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. MIYAZAKI Akihiro (10305237)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
4. SOGABE Yohei (50468104)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. YAMAGUCHI Akira (10210353)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. ODAJIMA Tetsuyo (00177239)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KOHAMA Gen-iku (80014009)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NAGAI Itaru (30136957)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NOGUCHI Makoto (50208328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. DEHARI Hironari (00381260)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
11. NAKAMORI Kenji (60295334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
12. KOBAYASHI Jyunichi (80404739)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
13. YOKOI Tosikazu (30230634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 関口隆 (00240929)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. SASAKI Takanori (50548732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. YAMAMOTO Takashi (50448594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. SHIMANISHI Makoto (10516561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
18. MICHIFURI Yoshitaka (00457722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. IDE Takashi (70274933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KISHABA Manabu (50224936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NATSUME Nagato (90183532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. HIRAHARA Humiki (30201734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TAKADO Tsuyoshi (90171454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TOZUKA Yasunori (00109456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KOMURA Takeshi (10334434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KIDO Sachie (20363690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 宮川明 (70166122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 平田章二 (50218781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 津波古判 (00253964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 田中信幸 (50163548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 上田愛 (80568105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. 片岡親男

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. HIROHASHI Yoshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
34. 鳥越俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 佐藤昇志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 田村保明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hiratsuka Hiroyoshi 平塚 博義

平塚 博義 ヒラツカ ヒロヨシ

HIRATSUKA Hiroyoshi 平塚 博義

HIRATSUKA Hiroyosi 平塚 博義

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The elucidation of tumor microenvironment in invasive front of oral cancer and its application to therapyPrincipal Investigator

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Development of a novel cancer vaccine that targets oral cancer stem cellsPrincipal Investigator

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Analysis of the β catenin gene abnormality and therapeutic application for oral cancer.Principal Investigator

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EVALUATION OF GRADE OF MALIGNANCY AND ITS CLINICAL USE ON THE BASIS OF SFRP METHYLATION IN ORAL SQUAMOUS CELL CARCINOMAPrincipal Investigator

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Combined evaluation of lymph node metastasis in squamous cell carcinoma of the oral cavityPrincipal Investigator

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Diagnosis and treatment of cervical lymph node metastasis based on expression of cadherin-catenin complexPrincipal Investigator

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Hiratsuka Hiroyoshi 平塚博義

平塚博義ヒラツカヒロヨシ

HIRATSUKA Hiroyoshi 平塚博義

HIRATSUKA Hiroyosi 平塚博義