KAGABU Shinzo 利部伸三

Researcher Number	50185708
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2006: 岐阜大学, 教育学部, 教授
Review Section/Research Field	Principal Investigator Bioproduction chemistry/Bioorganic chemistry
Keywords	Principal Investigator pharmacophore / metabolism / half-life / structure activity relationship / insect nerve activity / prodrug / imidacloprid / neonicotinoid / 置換ピリジン / 酸化反応 … More / アセタール / 昆虫神経活性 / ファーマコフォア / 代謝 / 半減期 / 構造活性相関 / 昆虫神経 / プロドラッグ / イミダクロプリド / ネオニコチノイド Less

Research Projects
(1 results)
Research Products
(25 results)

Design of neonicotinoid molecules based on the prodrug conceptPrincipal Investigator
- Principal Investigator
  
  KAGABU Shinzo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Gifu University

All 2007 2006 2005

All Journal Article

[Journal Article] Is pyridylmethyl group of imidacloprid replaceable with fluoroalkyl moiety as a hydrogen-bond acceptor?2007
- Author(s)
  利部伸三, 青木英司, 大野育也
- Journal Title
  
  Journal of Pesticide Science (印刷中)
- NAID
  110006273857
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore.2007
- Author(s)
  Shinzo Kagabu, Rilca Ishihara, Yosuke Hieda, Keiichiro Nishimura, Yuji Naruse
- Journal Title
  
  Journal of Agricultural Food Chemistry 55(3)
  
  Pages: 812-818
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Is pyridylmethyl group of imidacloprid replaceable with fluoroalkyl moiety as a hydrogen-bond acceptor?2007
- Author(s)
  Shinzo Kagabu, Eiji Aoki, Ikuya Ohno
- Journal Title
  
  Journal of Pesticide Science 32(2)
  
  Pages: 128-130
- NAID
  110006273857
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Is pyridylmethyl group of imidacloprid replaceable with fluoroalkyl moiety as a hydrogen-bond acceptor?2007
- Author(s)
  S.Kagabu, E.Aoki and I.Ohno
- Journal Title
  
  Journal of Pesticide Science 32・2
  
  Pages: 128-130
- NAID
  110006273857
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Effect of substituents at the 5-position of the pyridine ring of imidcaloprid on insecticidal activity against Periplaneta americana2007
- Author(s)
  S.Kagabu, Y.Murase, R.Imai, N.Ito and K.Nishimura
- Journal Title
  
  Pest Management Sclence 63・1
  
  Pages: 75-83
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Molecular design of proinsecticides: in vitro and in vivo hydrolysis of N-(5-methy1-2-oxo-1,3-dioxol-4yl)methyl derivatives of imidacloprid and 1-cholorothiazolylmethy1-2-nitroimino-imidazolidine2007
- Author(s)
  I.Ohno, K.Hirata, C.Ishida, M.Ihara, K.Matsuda and S.Kagabu
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Molecular design of proinsecticides : in vitro and in vivo hydrolysis of N-(5-methyl-2-oxo-1,3-dioxol-4-yl) methyl derivatives of imidacloprid and 1-chlorothiazolylmethyl-2-nitroimino-imidazolidine2007
- Author(s)
  大野育也, 石田千春, 平田幸一, 伊原誠, 松田一彦, 利部伸三
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry Letters (印刷中)
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Effect of substituents at the 5-position of the pyridine ring of imidcaloprid on insecticidal activity against Periplaneta americana.2007
- Author(s)
  Shinzo Kagabu, Yuko Murase, Rie Imai, Nakako Ito, Keiichiro Nishimura
- Journal Title
  
  Pest Management Science 63(1)
  
  Pages: 75-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Molecular design of proinsecticide : in vitro and in vivo hydrolysis of N-(5-methyl-2-oxo-1, 3-dioxol-4-yl) methyl derivatives of imidacloprid and 1-chlorothiazolylmethy 1- 2-nitroimino-imidazolidine2007
- Author(s)
  Ikuya Ohno, K. Hirata, C. Ishida,, M. Ihara, K. Matsuda S. Kagabu
- Journal Title
  
  Bio organic & Medicinal Chemistry Letters (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacore2007
- Author(s)
  S.Kagabu, R.Ishihara, Y.Hieda, K.Nishimura and Y.Naruse
- Journal Title
  
  Journal of Agricultural Food Chemistry 55・3
  
  Pages: 812-818
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Quantitative structure-activity relationships of imidacloprid and its analogs with substituents at the C5 position on the pyridine ring in the neuroblocking activity2006
- Author(s)
  K.Nishimura, K.Kiriyama and S.Kagabu
- Journal Title
  
  Journal of Pesticide Science 31・2
  
  Pages: 110-115
- NAID
  10018328735
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Quantitative structure-activity relationships of imidacloprid and its analogs with substituents at the C5 oposition on the pyridine ring in the neuroblocking activity.2006
- Author(s)
  Keiichiro Nishimura, Kazuhisa Kiriyama, Shinzo Kagabu
- Journal Title
  
  Journal of Pesticide Science 31(2)
  
  Pages: 110-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Insecticidal activity of imidacloprid derivatives with an alkoxy group at the CS position of the pyridine ring.2006
- Author(s)
  Shinzo Kagabu, Yuya Fujii, Keiichiro Nishimura
- Journal Title
  
  Journal of Pesticide Science 31(2)
  
  Pages: 150-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Insecticidal activity of imidacloprid derivatives with analkoxy group at the C5 position of the pyridine ring2006
- Author(s)
  S.Kagabu, Y.FujiiahdK, Nishimura
- Journal Title
  
  Journal of Pesticide Science 31・2
  
  Pages: 150-155
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Quantitative structure-activity relationships of imidacloprid and its analogs with substituents at the C5 oposition on the pyridine ring in the neuroblocking activity.2006
- Author(s)
  西村勁一郎, 桐山和久, 利部伸三
- Journal Title
  
  Journal of Pesticide Science 31・2
  
  Pages: 110-115
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Insecticidal activity of imidacloprid derivatives with an alkoxy group at the C5 position of the pyridine ring.2006
- Author(s)
  利部伸三, 藤井裕矢, 西村勁一郎
- Journal Title
  
  Journal of Pesticide Science 31・2
  
  Pages: 150-155
- NAID
  10018328870
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Methyl, trifluoromethyl, and methoxycarbonyl introduction to the fifth position on the pyridine ring of chloronicotinyl insecticide imidacloprid.2006
- Author(s)
  利部伸三
- Journal Title
  
  Synthetic Communications 36・9
  
  Pages: 1235-1245
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imicacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore.2006
- Author(s)
  利部伸三, 石原里佳, 稗田洋祐, 西村勁一郎, 成瀬有二
- Journal Title
  
  Journal of Agricultural Food Chemistry 55・3
  
  Pages: 812-818
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Methyl, trifluoromethyl, and methoxycarbonyl introduction to the fifth position on the pyridine ring of chioronicotinyl insecticide imidacloprid.2006
- Author(s)
  Shinzo Kagabu
- Journal Title
  
  Synthetic Communications 36(9)
  
  Pages: 1235-1245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Methyl, trifluoromethyl, and methoxycarbonyl introduction to the fifth position on the pyridine ring of chloronicotinyl insecticide imidacloprid2006
- Author(s)
  S.Kagabu
- Journal Title
  
  Synthetic Communications 36・9
  
  Pages: 1235-1245
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Effects of substituents at the 5-position of the pyridine ring of imidcaloprid on insecticidal activity against Periplaneta americana.2006
- Author(s)
  利部伸三, 村瀬ゆう子, 今井里英, 伊藤菜花子, 西村勁一郎
- Journal Title
  
  Pest Management Science 63.1
  
  Pages: 75-83
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Effects of halogen introduction at the C5 position of the imidacloprid pyridine ring upon insecticidal activity2005
- Author(s)
  S.Kagabu, N.Ito, R.Imai, Y.Hieda, and K.Nishimura
- Journal Title
  
  Journal of Pesticide Science 30・4
  
  Pages: 409-413
- NAID
  110002323365
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Effects of halogen introduction at the C5 position of the imidaclopridpyridin ring upon insecticidal activity.2005
- Author(s)
  利部伸三, 伊藤菜花子, 今井里英, 稗田洋祐, 西村勁一郎
- Journal Title
  
  Journal of Pesticide Science 30・4
  
  Pages: 409-413
- NAID
  110002323365
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Effects of halogen introduction at theC5 position of the imidacloprid pyridine ring upon insecticidal activity.2005
- Author(s)
  Shinzo Kagabu, Nakako Ito, Rie Imai, Yosuke Hieda, Keiichiro Nishimura
- Journal Title
  
  Journal of Pesticide Science 30(4)
  
  Pages: 409-413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580094
[Journal Article] Effects of halogen introduction at the C5 position of the imidacloprid pyridine ring upon insecticidal activity2005
- Author(s)
  Shinzo Kagabu, Nakako Ito, Bie Imai, Yosuke Hieta, Keiichiro Nishimura
- Journal Title
  
  Journal of Pesticide Science 30・4
  
  Pages: 409-413
- NAID
  110002323365
- Data Source
  KAKENHI-PROJECT-17580094

KAGABU Shinzo 利部 伸三

Research Projects

Research Products

Design of neonicotinoid molecules based on the prodrug conceptPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Is pyridylmethyl group of imidacloprid replaceable with fluoroalkyl moiety as a hydrogen-bond acceptor?2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Is pyridylmethyl group of imidacloprid replaceable with fluoroalkyl moiety as a hydrogen-bond acceptor?2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Is pyridylmethyl group of imidacloprid replaceable with fluoroalkyl moiety as a hydrogen-bond acceptor?2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Effect of substituents at the 5-position of the pyridine ring of imidcaloprid on insecticidal activity against Periplaneta americana2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Molecular design of proinsecticides: in vitro and in vivo hydrolysis of N-(5-methy1-2-oxo-1,3-dioxol-4yl)methyl derivatives of imidacloprid and 1-cholorothiazolylmethy1-2-nitroimino-imidazolidine2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Molecular design of proinsecticides : in vitro and in vivo hydrolysis of N-(5-methyl-2-oxo-1,3-dioxol-4-yl) methyl derivatives of imidacloprid and 1-chlorothiazolylmethyl-2-nitroimino-imidazolidine2007

Author(s)

Journal Title

Data Source

[Journal Article] Effect of substituents at the 5-position of the pyridine ring of imidcaloprid on insecticidal activity against Periplaneta americana.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Molecular design of proinsecticide : in vitro and in vivo hydrolysis of N-(5-methyl-2-oxo-1, 3-dioxol-4-yl) methyl derivatives of imidacloprid and 1-chlorothiazolylmethy 1- 2-nitroimino-imidazolidine2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacore2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Quantitative structure-activity relationships of imidacloprid and its analogs with substituents at the C5 position on the pyridine ring in the neuroblocking activity2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Quantitative structure-activity relationships of imidacloprid and its analogs with substituents at the C5 oposition on the pyridine ring in the neuroblocking activity.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Insecticidal activity of imidacloprid derivatives with an alkoxy group at the CS position of the pyridine ring.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Insecticidal activity of imidacloprid derivatives with analkoxy group at the C5 position of the pyridine ring2006

Author(s)

Journal Title

Description

KAGABU Shinzo 利部伸三