KARASAWA Ken 唐澤健

… Alternative Names

唐澤健カラサワケン

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Researcher Number	50186029
Other IDs
External Links
Affiliation (Current)	2025: 帝京大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2005 – 2006: 帝京大学, 薬学部, 教授 2001 – 2004: 帝京大学, 薬学部, 助教授 1999 – 2000: 帝京大学, 薬学部, 講師 1995 – 1997: 帝京大学, 薬学部, 講師 1993 – 1994: 帝京大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator PAF / PAF-アセチルヒドロラーゼ / LDL / Red blood cells / 酸化脂質 / 赤血球 / PAF-acetylhydrolase / 血小板活性化因子 / PAFアセチルヒドロラーゼ / Oxidized lipids … More / Mass spectrometry / PAF-acetylhydrolases / 質量分析法 / Oxidized liuids / Oxidative stress / Platelet-activating factor (PAF) / 酸化ストレス / 血小板活性化因子(PAF) / glycosylation / gene transfer / platelet-activating factor / 糖鎖修飾 / 遺伝子導入 / Molecular Cloning / PAF-Acetylhydrolase / PAF (Platelet-Activating Factor) / PAT / 遺伝子クローニング / 動脈硬化 / 酸化リン脂質 / アセチルハイドロラーゼ / 過酸化りん脂質分解産物 … More Except Principal Investigator PAF / enzyme purification / PAF synthetic enzyme / membrane bound enzyme / Platelet Activating Factor / 膜結合酵素の精製 / PAF合成酵 / 酵素精製 / 膜結合型酵素 / PAF合成酵素 / platelet activating factor / 血小板活性化因子 / lysoPAF-acetyltransferase / Genomic DNA Cloning / cDNA Cloning / PAF (Platelet-Activating Factor) / PAF-Acetylhydrolase / 遺伝子クローニング / タンパク精製 / PAFアセチルトランスフェラーゼ / lysoPAFアセチルトランスフェラーゼ / 1ysoPAFアセチルトランスフェラーゼ / ゲノムDNAクローニング / cDNAクローニング / 血小板活性化因子(PAF) / PAFアセチルヒドロラーゼ Less

Protective role of blood PAF-acetylhydrolases against oxidation of lipidsPrincipal Investigator
- Principal Investigator
  
  KARASAWA Ken
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University
Protective role of red blood cells PAF-acetylhydrolase against oxidative siessPrincipal Investigator
- Principal Investigator
  
  KARASAWA Ken
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University
NEW APPROACH TO PURIFICATION OF MEMBRANE-BOUND ENZYME - APPLIED TO PAF SYNTHETIC ENZYME PURIFICATION
- Principal Investigator
  
  SETAKA Morio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  TEIKYO UNIVERSITY
The role of glycohydrates in the function of plasma-type PAF-acetylhydrolase.Principal Investigator
- Principal Investigator
  
  KARASAWA Ken
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University
Molecular biological and biochemical study of plasms platelet-activating factor-metabolic enzymes for new anti-PAF drugs
- Principal Investigator
  
  SETAKA Morio
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University
Molecular biological and biochemical study of plasma Platelet-activating factor-acetylhydrolase ; its regulation and functionPrincipal Investigator
- Principal Investigator
  
  KARASAWA Ken
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University
酸化ストレスにより生成する過酸化リン脂質の血管病変における役割Principal Investigator
- Principal Investigator
  
  唐澤健
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University
過酸化リン脂質分解産物の炎症反応における役割に関する免疫化学的研究Principal Investigator
- Principal Investigator
  
  唐澤健
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University

All 2006 2005 2003 Other

All Journal Article

[Journal Article] Clinical aspects of plasma platelet-activating factor acetylhydrolase.2006
- Author(s)
  Ken Karasawa
- Journal Title
  
  Biochim. Biophys.Acta 1761
  
  Pages: 1359-1372
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Clinical aspects of plasma platelet-activating factor acetylhydrolase.2006
- Author(s)
  Ken Karasawa
- Journal Title
  
  Biochim. Biophys. Acta 1761
  
  Pages: 1359-1372
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Clinical aspects of plasma platelet-activating factor acetylhydrolase2006
- Author(s)
  Ken Karasawa
- Journal Title
  
  Biochim.Biophys.Acta 1761
  
  Pages: 1359-1372
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Red blood cells highly express type I platelet-activating factor acetylhydrolase (PAF-AH) which consists of α1/α2 complex.2005
- Author(s)
  Ken Karasawa, Mariko Shirakura, Noriko Satoh, Ayako Harada, Kazuaki Yokoyama, Morio Setaka, Keizo Inoue
- Journal Title
  
  J. Biochem. 138
  
  Pages: 509-517
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Adenovirus-mediated gene transfer and lipoprotein-mediated protein delivery of plasma PAF-AH ameliorates proteinuria in rat model of glomerulosclerosis.2005
- Author(s)
  Naoyuki Iso-O, Hiroshi Noto, Masumi Hara, Masako Togo, Ken Karasawa, Noriko Ohashi, Eisei Noiri, Yoshiaki Hashimoto, Takashi Kadowaki, Satoshi Kimura, Tsuyoshi Watanabe, Kazuhisa Tsukamoto
- Journal Title
  
  Ther 113
  
  Pages: 118-126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Local expression of platlet-activating factor-acetylydrolase reduces accumulation of oxidized lipoproteins and inhibits inflammation, shear stress-induced thrombosis, and neointima formation in balloon-injured carotid arteries in nonhyperlipidemic rabbits2005
- Author(s)
  Hideki Arakawa, Jian-Yong Qian, Dolgor Baatar, Ken Karasawa, Yujiro Asada, Yasuyuki Sasaguri, Elizabeth R. Miller, Joseph L. Wiztum, Hikaru Ueno
- Journal Title
  
  Circulation. 111
  
  Pages: 3302-3309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Red blood cells highly express type I PAF-acetylhydrolase which consists of α_1/α_2 complex.2005
- Author(s)
  Ken Karasawa
- Journal Title
  
  J. Biochem. 138(4)
  
  Pages: 509-517
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Red blood cells highly express type I PAF-acetylhydrolase which consists of α_1/α_2 complex.2005
- Author(s)
  Ken Karasawa
- Journal Title
  
  J.Biochem. 138(4)
  
  Pages: 509-517
- Data Source
  KAKENHI-PROJECT-17590069
[Journal Article] Human Plasma Platelet-activating Factor Acetylhydrolase Binds to All the Murine Lipoproteins, Conferring Protection against Oxidative Stress.2003
- Author(s)
  Hiroshi Noto, Masumi Hara, Ken Karasawa, Naoyuki Iso-O, Hiroaki Satoh, Masako Toga, Yoshiaki Hashimoto, Yoshiji Yamada, Tetsuya Kosaka, Mitsunobu Kawamura, Satoshi, Kimura., Kazuhisa Tsukamoto
- Journal Title
  
  Artherioscler.Thromb.Vasc.Biol. 23
  
  Pages: 829-835
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590069
[Journal Article] Regulation of Activities of CDP-choline : 1 -O-alkyl-2-acetyl-sn-glycerol Cholinephosphotransferase (AAG-CPT), an Enzyme Responsible for de novo Synthesis of Platelet-activating Factor (PAF), by Membrane Phospholipids.2003
- Author(s)
  Noriko Satoh, Ayako Harada, Kazuaki Yokoyama, Ken Karasawa, Keizo Inoue, Mono Setaka
- Journal Title
  
  J.Health.Sci 49
  
  Pages: 13-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590069
[Journal Article] Plasma Platelet activating Factor-acetylhydrilase (PAF-AH)2003
- Author(s)
  Ken Karasawa, Ayako Harada, Noriko Satoh, Keizo Inoue, Morio Setaka
- Journal Title
  
  Prog.Lipid.Res. 42
  
  Pages: 93-114
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590069
[Journal Article] Plasma Platelet-activating Factor-acetylhydrolase (PAF-AH).2003
- Author(s)
  Ken Karasawa, Ayako Harada, Noriko Satoh, Keizo Inoue, Morio Setaka
- Journal Title
  
  Prog.Lipid.Res. 42
  
  Pages: 93-114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590069
[Journal Article] Regulation of Activities of CDP-choline:1-0-alkyl-2-acetyl-sn-glycerol Cholinephosphotransferase (AAG-CPT), an Enzyme Responsible for de novo Synthesis of Platelet-Activating Factor (PAF), by Membrane Phospholipids.2003
- Author(s)
  Noriko Satoh, Ayako Harada, Kazuaki Yokoyama, Ken Karasawa, Keizo Inoue, Morio Setaka
- Journal Title
  
  J.Health.Sci 49
  
  Pages: 13-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590069
[Journal Article] Human Plasma Platelet-activating Factor Acetylhydrolase Binds to All the Murine Lipoproteins, Conforring Protection against Oxidetive Stress.2003
- Author(s)
  Hiroshi Noto, Masumi Hara, Ken Karasawa, Naoyuki Iso-O, Hiroaki Satoh, Masako Toga, Yoshiaki Hashimoto, Yoshiji Yamada, Tetsuya Kosaka, Mitsunobu Kawamura, Satoshi, Kimura, Kazuhisa Tsukamoto
- Journal Title
  
  Artherioseler.Thromb, Vasc.Biol. 23
  
  Pages: 829-835
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590069
[Journal Article] Analysis of oxidized phosphatidylcholines using theoretically expanded multiple reaction monitoring with reversed-phase liquid chromatography/tandem mass spectrometry.
- Author(s)
  Yasuhiro Iida, Takahiro Suzuki, Ken Karasawa, Takao Shimizu, Ryo Taguchi
- Journal Title
  
  J. Am. Soc. Mass. Spectrom (in the press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590069

1. SATO Noriko (80162460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. SETAKA Morio (70012630)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YOKOYAMA Kazuaki (50246021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUJITA Masamichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SHIMIZU Fuzuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KARASAWA Ken 唐澤 健

唐澤 健 カラサワ ケン

Research Projects

Research Products

Co-Researchers

Protective role of blood PAF-acetylhydrolases against oxidation of lipidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protective role of red blood cells PAF-acetylhydrolase against oxidative siessPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NEW APPROACH TO PURIFICATION OF MEMBRANE-BOUND ENZYME - APPLIED TO PAF SYNTHETIC ENZYME PURIFICATION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of glycohydrates in the function of plasma-type PAF-acetylhydrolase.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological and biochemical study of plasms platelet-activating factor-metabolic enzymes for new anti-PAF drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological and biochemical study of plasma Platelet-activating factor-acetylhydrolase ; its regulation and functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

酸化ストレスにより生成する過酸化リン脂質の血管病変における役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

過酸化リン脂質分解産物の炎症反応における役割に関する免疫化学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Clinical aspects of plasma platelet-activating factor acetylhydrolase.2006

Author(s)

Journal Title

Data Source

[Journal Article] Clinical aspects of plasma platelet-activating factor acetylhydrolase.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Clinical aspects of plasma platelet-activating factor acetylhydrolase2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Red blood cells highly express type I platelet-activating factor acetylhydrolase (PAF-AH) which consists of α1/α2 complex.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Adenovirus-mediated gene transfer and lipoprotein-mediated protein delivery of plasma PAF-AH ameliorates proteinuria in rat model of glomerulosclerosis.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Local expression of platlet-activating factor-acetylydrolase reduces accumulation of oxidized lipoproteins and inhibits inflammation, shear stress-induced thrombosis, and neointima formation in balloon-injured carotid arteries in nonhyperlipidemic rabbits2005

Author(s)

Journal Title

KARASAWA Ken 唐澤健

唐澤健カラサワケン