SHIMIZU EIJI 清水英治

… Alternative Names

SHIMIZU Eiji 清水英治

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Researcher Number	50187449
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014 – 2017: 鳥取大学, 医学部, 教授 2009 – 2012: 鳥取大学, 医学部, 教授 2005 – 2007: 鳥取大学, 医学部, 教授 2002 – 2003: 鳥取大学, 医学部, 教授 1999: TOTTORI UNIVERSITY, DEPARTMENT OF 3RD INTERNAL MEDICINE, SCHOOL OF MEDICINE, PROFESSOR, 医学部, 教授 … More 1997 – 1999: 徳島大学, 医学部, 講師 1994 – 1995: 徳島大学, 医学部, 講師 1989: The University of Tokushima Assistant internist, 医学部・附属病院, 講師 1988: 徳島大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine / 電磁場環境 / 応用薬理学・医療系薬学 / Environmental physiology (including Physical medicine and Nutritional physiology) / Emergency medicine
Keywords	Principal Investigator RB / 癌遺伝子 / 肺癌 / ULBP-2 / ProGRP / lung cancer / ELISA / 癌抑制遺伝子 / Oncogene / Lung cancer … More / 化学療法 / PBSC / 胸膜中皮腫 / anti-p53 autoantibody / tumor marker / serum / コチニン / p53自己抗体 / 腫瘍マーカー / 血清 / 肺癌検診 / health examination / antibody / tumor suppressor gene / 血清診断 / 癌制遺伝子 / 検診 / 網膜芽細胞腫 / 癌遺伝子産物抗体 / 早期診断 / 早期発見 / 抗Rb抗体 / 健診 / 抗体 / Cisplatin / Pleuritis carcinomatosa / Chemotherapy / Gene therapy / p16, rb / Tumor suppressor gene / コロニー形成試験 / 抗癌剤感受性試験 / p16 / シスプラチン / 癌性胸膜炎 / 遺伝子治療 / p16 rb / SCF / Cyclin / Peripheral blood stem cell transplant / hematopoietic stem cell / NK cell / High dose chemotherapy / 自家移植 / サイトカイン / 末梢血幹細胞移植術 / 造血幹細胞 / NK細胞 / 大量化学療法 / 耐性 / 臨床呼吸器学 / ペメトレキセド / 悪性胸膜中皮腫 / 分子標的治療 … More Except Principal Investigator Adrenal Chromaffin Cells / 副腎クロマフィン細胞 / 内科 / 生理学 / 時計遺伝子 / 睡眠時無呼吸症候群 / NK細胞 / 肺癌 / 免疫療法 / Lymphocyte / Eosinophil colony stimulating factor / Eosinophilia / 好酸球遊走因子 / 好酸球コロニー刺激因子 / リンパ球 / 好酸球 / PIE症候群 / 気管支喘息 / T-リンパ球 / インタ-ロイキン-5 / 好酸球コロニ-刺激因子 / 好酸球増多症 / sleep apnea syndrome / clock gene / circadian rhythm / gene / Internal medicine / Physiology / 概日リズム / 遺伝子 / Bradykinin / Intracellular Free Calcium / Magnetic Field / 強磁界 / カルシウムイオン / 神経細胞 / Anti-hypertensive Drugs / Calcium Efflux / Neuronal Cells / 高血圧治療薬 / カルシウム排出 / 興奮性細胞 / EPIDEMIOLOGICAL STUDY / ACTIVITIES OF DAILY LIFE (ADL) / OBESITY / EXERCISE TRAINING / FOOD HABIT / VLDL CHOLESTEROL / LYMPHOCYTE PROLIFERATION / VITAMIN E / AGED PEOPLE / CELLULAR IMMUNITY / NK活性 / 幼若化能 / 免疫能 / 末梢血リンパ球 / 日常生活機能(ADL) / 体格指数(BMI) / 血清アルブミン値 / 疫学調査 / 運動機能 / 食習慣 / 血中脂質 / リンパ球増殖能 / ビタミンE / 高齢者 / 細胞性免疫能 / 可溶性ULBP2 / ULBP2 / 敗血症 / 薬剤反応 / 薬剤反応性 / 低酸素 / 内科学 / VEGF / IL-6 / 間歇的低酸素 / 抗体治療 / 免疫遺伝子治療 / 薬剤耐性 / サイトカイン / ADCC / モノクローナル抗体 / ガンクリオシドGM2 / 転移モデル / SCIDマウス / 遺伝子治療 / P糖蛋白質 / 多剤耐性 / 転移 / 肺がん Less

Development of the new clinical cure to overcome pemetrexed tolerance for malignant pleural mesotheliomaPrincipal Investigator
- Principal Investigator
  
  SHIMIZU EIJI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
A novel therapy for sepsis by regulating soluble ULBP2
- Principal Investigator
  
  CHIKUMI HIROKI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Tottori University
Development of novel therapy for malignant mesothelioma by controllingADCC activity.Principal Investigator
- Principal Investigator
  
  SHIMIZU Eiji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Development of novel biomarker for cetuximab therapy in lung cancer
- Principal Investigator
  
  CHIKUMI Hiroki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Influence of sleep apnea syndrome on clock gene dysfunction
- Principal Investigator
  
  BURIOKA Naoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Measurement of newly developed tumor markers and molecular markers in health screening for lung cancerPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Eiji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Clock gene dysfunction in patients with obstructive sleep apnea syndrome
- Principal Investigator
  
  BURIOKA Naoto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University
Measurement of antibodies against tumor suppressor gene products in health screening for lung cancerPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Eiji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tottori University Faculty of Medicine
STUDIES ON THE EFFECTS OF NUTRITION AND EXERCISE ON THE DECREASED CELLULAR IMMUNITY IN THE AGED
- Principal Investigator
  
  MORIGUCHI Satoru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Yamaguchi Prefectural University
Physiological Role of Calcium Efflux from Neuronal Cells and Its Regulation by Drugs
- Principal Investigator
  
  MINAKUCHI Kazuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  The University of Tokushima
Effects of Time-varying Magnetic Field on Stimulus-secretion Coupling and Its Application for Environmental Criterion
- Principal Investigator
  
  HOUCHI Hitoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  電磁場環境
- Research Institution
  The University of Tokushima
Gene therapy for lung cancer using tumor suppressor gene product as molecular targetPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Eiji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tokushima
肺がんの薬剤耐性と転移因子を分子標的とした免疫遺伝子治療
- Principal Investigator
  
  曽根三郎
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokushima
Basic and clinical research of peripheral blood stem cell transplant (PBSCT) in chemotherapy for lung cancerPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Eiji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tokushima
Regulation of release of eosinophil colony stimulating factors and chemotactic factors from lymphocytes of patients withdiseases.
- Principal Investigator
  
  OZAKI Toshio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima

All 2018 2017 2016 2015 2014 2012 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] 今日の治療指針20172017
- Author(s)
  清水英治
- Total Pages
  1
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-26461159
[Book] 内科学2017
- Author(s)
  鰤岡直人、清水英治
- Total Pages
  4
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] γ-Tocotrienol Inhibits TGF-β1-Induced Contractile Phenotype Expression of Human Airway Smooth Muscle Cells.2018
- Author(s)
  Fukushima T, Yamasaki A, Harada T, Chikumi H, Watanabe M, Okazaki R, Takata M, Hasegawa Y, Kurai J, Yanai M, Yamamoto A, Sueda Y, Halayko AJ, Shimizu E.
- Journal Title
  
  Yonago Acta Med.
  
  Volume: 60 Pages: 16-23
- NAID
  120005999117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] Evaluation of antigen‐positive toxin‐negative enzyme immunoassay results for the diagnosis of toxigenic Clostridium difficile infection2018
- Author(s)
  Akamatsu Y, Morishita S, Okamoto R, Okada K, Kitaura T, Miyake N, Yamaguchi K, Nakamoto M, Shimohiro H, Takata M, Yamasaki A, Burioka N, Shimizu E.
- Journal Title
  
  J. Med. Invest.
  
  Volume: 65 Issue: 1.2 Pages: 131-135
- DOI
  10.2152/jmi.65.131
- NAID
  130006575562
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159, KAKENHI-PROJECT-26462755
[Journal Article] A novel SLC34A2 mutation in a patient with pulmonary alveolar microlithiasis.2017
- Author(s)
  Izumi H, Kurai J, Kodani M, Watanabe M, Yamamoto A, Nanba E, Adachi K, Igishi T, Shimizu E.
- Journal Title
  
  Hum Genome Var
  
  Volume: 26 Issue: 1 Pages: 1647-1647
- DOI
  10.1038/hgv.2016.47
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] A case of proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) positive/IgG4-related lung disease.2017
- Author(s)
  Touge H, Tomita K, Yamasaki A, Shimizu E.
- Journal Title
  
  Respir Med Case Rep
  
  Volume: 20 Pages: 92-94
- DOI
  10.1016/j.rmcr.2017.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] γ-Tocotrienol Inhibits TGF-β1-Induced Contractile Phenotype Expression of Human Airway Smooth Muscle Cells2017
- Author(s)
  Fukushima T, Yamasaki A, Harada T, Chikumi H, Watanabe M, Okazaki R, Takata M, Hasegawa Y, Kurai J, Yanai M, Yamamoto A, Sueda Y, Halayko AJ, Shimizu E.
- Journal Title
  
  Yonago Acta Med
  
  Volume: 60 Pages: 16-23
- NAID
  120005999117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] A case of lung abscess successfully treated by transbronchial drainage using a guide sheath.2017
- Author(s)
  Izumi H, Kodani M, Matsumoto S, Kawasaki Y, Igishi T, Shimizu E.
- Journal Title
  
  Respirol Case Rep
  
  Volume: 5 Issue: 3 Pages: 228-230
- DOI
  10.1002/rcr2.228
- NAID
  120007146980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Development of fever following first administration of zoledronate as a prognostic factor in advanced non-small cell lung cancer patients with bone metastases.2017
- Author(s)
  Izumi H, Igishi T, Yamasaki A, Takeda K, Yanai M, Tanaka N, Sakamoto T, Nishii-Ito S, Touge H, Kodani M, Matsumoto S, Kawasaki Y, Shimizu E.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 7 Pages: 1000-1004
- DOI
  10.3892/mco.2017.1447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Frequency of Epidermal Growth Factor Receptor Mutation in Smokers with Lung Cancer Without Pulmonary Emphysema.2017
- Author(s)
  Takeda K, Yamasaki A, Igishi T, Kawasaki Y, Ito-Nishii S, Izumi H, Sakamoto T, Touge H, Kodani M, Makino H, Yanai M, Tanaka N, Matsumoto S, Araki K, Nakamura H, Shimizu E.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Pages: 765-771
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] γ-Tocotrienol Inhibits TGF-β1-Induced Contractile Phenotype Expression of Human Airway Smooth Muscle Cells.2017
- Author(s)
  Fukushima T, Yamasaki A, Harada T, Chikumi H, Watanabe M, Okazaki R, Takata M, Hasegawa Y, Kurai J, Yanai M, Yamamoto A, Sueda Y, Halayko AJ, Shimizu E.
- Journal Title
  
  Yonago Acta Med
  
  Volume: 60 Pages: 16-23
- NAID
  120005999117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] DNA-PK Inhibition by NU7441 Enhances Chemosensitivity to Topoisomerase Inhibitor in Non-Small Cell Lung Carcinoma Cells by Blocking DNA Damage Repair.2017
- Author(s)
  Yanai M, Makino H, Ping B, Takeda K, Tanaka N, Sakamoto T, Yamaguchi K, Kodani M, Yamasaki A, Igishi T, Shimizu E.
- Journal Title
  
  Yonago Acta Med
  
  Volume: 60 Pages: 9-15
- NAID
  120005999118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] An onion farmer with a case of hypersensitivity pneumonitis caused by Aspergillus niger.2017
- Author(s)
  Sakamoto T, Yamasaki A, Funaki Y, Harada T, Okazaki R, Hasegawa Y, Sueda Y, Fukushima T, Morita M, Yamamoto A, Kodani M, Shimizu E.
- Journal Title
  
  Respir Med Case Rep
  
  Volume: 23 Pages: 60-62
- DOI
  10.1016/j.rmcr.2017.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year.2016
- Author(s)
  Nishii-Ito S, Izumi H, Touge H, Takeda K, Hosoda Y, Yamasaki A, Kuwamoto S, Shimizu E, Motokura T.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 5 Issue: 6 Pages: 689-692
- DOI
  10.3892/mco.2016.1063
- NAID
  120007144887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Association between Outdoor Fungal Concentrations during Winter and Pulmonary Function in Children with and without Asthma.2016
- Author(s)
  Watanabe M, Noma H, Kurai J, Hantan D, Burioka N, Nakamoto S, Sano H, Taniguchi J, Shimizu E.
- Journal Title
  
  Int J Environ Res Public Health
  
  Volume: 28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Properties of Achromobacter xylosoxidans highly resistant to aminoglycoside antibiotics.2016
- Author(s)
  Nakamoto S, Goda N, Hayabuchi T, Tamaki H, Ishida A, Suzuki A, Nakano K, Yui S, Katsumata Y, Yamagami Y, Burioka N, Chikumi H, Shimizu E.
- Journal Title
  
  Jpn J Antibiot
  
  Volume: 69 Pages: 113-118
- NAID
  40020827421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462755
[Journal Article] Difference in interleukin-8 transcriptional activity induced in THP-G8 cells by particulate matter collected in winter and summer in western Japan.2015
- Author(s)
  Watanabe M, Kurai J, Minato S, Noma H, Sano H, Saito R, Aiba S, Oshimura M, Hatakeyama K, Yamasaki A, Shimizu E.
- Journal Title
  
  J Med Invest
  
  Volume: 62 Pages: 145-148
- NAID
  130005099161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] A new rapid method for detecting epidermal growth factor receptor mutations in non-small cell lung cancer2015
- Author(s)
  Takata M, Chikumi H, Matsunami K, Kodani M, Sakamoto T, Hashimoto K, Nakamoto M, Okada K, Kitaura T, Matsumoto S, Kurai J, Yamasaki A, Igishi T, Burioka N, Shimizu E
- Journal Title
  
  Oncol Rep
  
  Volume: 33 Issue: 3 Pages: 1040-1048
- DOI
  10.3892/or.2015.3716
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase; inhibitory fluoropyrimidine in EGFR; mutated lung adenocarcinoma: retrospective and in vitro studies.2015
- Author(s)
  Izumi H, Touge H, Igishi T, Makino H, Nishii-Ito S, Takata M, Nakazaki H, Ueda Y, Matsumoto S, Kodani M, Kurai J, Takeda K, Sakamoto T, Yanai M, Tanaka N, Nirodi CS, Shimizu E.
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Issue: 3 Pages: 989-998
- DOI
  10.3892/ijo.2015.2815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] A novel point-of-care system for high-speed real-time polymerase chain reaction testing for epidermal growth factor receptor mutations in bronchial lavage fluids after transbronchial biopsy in patients with non-small cell lung cancer2015
- Author(s)
  Sakamoto T, Kodani M, Takata M, Chikumi H, Nakamoto M, Nishii-Ito S, Ueda Y, Izumi H, Makino H, Touge H, Takeda K, Yamasaki A, Yanai M, Tanaka N, Igishi T, Shimizu E
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Issue: 4 Pages: 1473-1480
- DOI
  10.3892/ijo.2015.2875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461159
[Journal Article] Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity2012
- Author(s)
  Takata M, Chikumi H, Miyake N, Adachi K, Kanamori Y, Yamasaki A, Igishi T, Burioka N, Nanba E, Shimizu E
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 13 Pages: 369-378
- URL
  http://dx.doi.org/10.4161/cbt.19238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994
[Journal Article] Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells2012
- Author(s)
  Miyake N, Chikumi H, Takata M, Nakamoto M, Igishi T, Shimizu E
- Journal Title
  
  Oncology reports 28
  
  Volume: 28 Pages: 848-854
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22313637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863
[Journal Article] Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity2012
- Author(s)
  Takata M, Shimizu E, et al
- Journal Title
  
  Cancer biology & therapy
  
  Volume: 13 Pages: 369-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863
[Journal Article] Diagnostic and Prognostic Impact of Serum Soluble UL16-Bin ding Protein 2 in Lung Cancer Patients2012
- Author(s)
  Yamaguchi K, Shimizu E, et al
- Journal Title
  
  Cancer Science
  
  Volume: 103(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863
[Journal Article] Therapeutic antitumor efficacy of anti-epidermal growth factor receptor antibody, cetuximab, against malignant pleural mesothelioma2012
- Author(s)
  Kurai J, Chikumi HT, Hamada H, Yano S, , Hashimoto K, Takata M, Sako T, Yamaguchi K, Kinoshita N, Watanabe M, Touge H, Makino H, Igishi Shimizu E
- Journal Title
  
  International Journal of Oncology
  
  Volume: 41 Issue: 5 Pages: 1610-1618
- DOI
  10.3892/ijo.2012.1607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863, KAKENHI-PROJECT-24390209, KAKENHI-PLANNED-22112010
[Journal Article] Diagnostic and Prognostic Impact of Serum Soluble UL16-Binding Protein 2 in Lung Cancer Patients2012
- Author(s)
  Yamaguchi K, Chikumi H, Shimizu A, Takata M, Kinoshita N, Hashimoto K, Nakamoto M, Matsunaga S, Kurai J, Miyake N, Matsumoto S, Watanabe M, Yamasaki A, Igishi T, Burioka N, Shimizu E
- Journal Title
  
  Cancer Science
  
  Volume: (in press) Issue: 8 Pages: 1405-1413
- DOI
  10.1111/j.1349-7006.2012.02330.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994, KAKENHI-PROJECT-22590863
[Journal Article] Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity2012
- Author(s)
  Takata M, Chikumi H, Miyake N, Adachi K, Kanamori Y, Yamasaki A, Igishi T, Burioka N, Nanba E, Shimizu E
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 13 Pages: 369-378
- URL
  http://dx.doi.org/10.4161/cbt.19238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863
[Journal Article] Asthma : chronopharmacotherapy and the molecular clock.2010
- Author(s)
  Burioka N, Fukuoka Y, Koyanagi S, Miyata M, Takata M, Chikumi H, Watanabe M, Endo M, Sako T, Suyama H, Ohdo S, Shimizu E.
- Journal Title
  
  Adv Drug Deliv Rev 62
  
  Pages: 946-955
- Data Source
  KAKENHI-PROJECT-20590923
[Journal Article] Influence of intermittent hypoxia on the signal transduction pathways to inflammatory response and circadian clock regulation.2009
- Author(s)
  Burioka N, Koyanagi S, Fukuoka Y, Okazaki F, Fujioka T, Kusunose N, Endo M, Suyama H, Chikumi H, Ohdo S, Shimizu E.
- Journal Title
  
  Life Sci 85
  
  Pages: 372-378
- Data Source
  KAKENHI-PROJECT-20590923
[Journal Article] Day-night variations of serum interleukin-6 in patients with severe obstructive sleep apnea syndrome before and after continuous positive airway pressure (CPAP).2008
- Author(s)
  Burioka N, Miyata M, Endo M, Fukuoka Y, Shimizu E.
- Journal Title
  
  Chronobiol Int 25
  
  Pages: 827-834
- Data Source
  KAKENHI-PROJECT-20590923
[Journal Article] Sequential treatment with SN-38 followed by 5-fluorouracil shows synergistic cytotoxic activity in small cell lung cancer cells2008
- Author(s)
  Takeda, K, Suyama, H, Igishi, T, Shigeoka, Y, Matsumoto, S, Yamasaki, A, Hashimoto, K, Sumikawa, T, Morita, M, Ueda, Y, Shimizu, E
- Journal Title
  
  Oncol Rep 19
  
  Pages: 945-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Dexamethasone interferes with trastuzumab-induced cell growth inhibition through restoration of AKT activity in BT-474 breast cancer cells2008
- Author(s)
  Sumikawa, T, Shigeoka, Y, Igishi, T, Suyama, H, Yamasaki, A, Hashimoto, K, Matsumoto, S, Takeda, K, Ueda, Y, Shimizu, E
- Journal Title
  
  Int J Oncol 32
  
  Pages: 683-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Clock gene dysfunction in patients with obstructive sleep apnea syndrome.2008
- Author(s)
  Burioka N, Koyanagi S, Takata M, Endo M, Fukuoka Y, Miyata M, Takeda K, Chikumi H, Ohdo S, Shimizu E.
- Journal Title
  
  Eur Respir J 32
  
  Pages: 105-112
- Data Source
  KAKENHI-PROJECT-20590923
[Journal Article] Treatment with β_2-adrenoceptor agonist in vivo induces human clock gene, Per1, mRNA expression in peripheral blood2007
- Author(s)
  Burioka N, Takata M, Endo M, Miyata M, Takeda K, Chikumi H, Tomita K, Fukuoka Y, Nakazaki H, Sano H, Shimizu E
- Journal Title
  
  Chronobiol Int 24(1)
  
  Pages: 183-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines2007
- Author(s)
  Kurai, J, Chikumi, H, Hashimoto, K, Yamaguchi, K, Yamasald, A, Sako, T, Touge, H, Makino, H, Takata, M, Miyata, M, Nakamoto, M, Burioka, N, Shimizu, E
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 1552-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Prevalence and specificity of LKB 1 genetic alterations in lung cancers2007
- Author(s)
  Matsumoto, S, Iwakawa, R, Takahashi, K, Kohno, T, Nakanishi, Y, Matsuno, Y, Suzuki, K, Nakamoto, M, Shimizu, E, Minna, JD, Yokota, J
- Journal Title
  
  Oncogene 26
  
  Pages: 5911-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Severe Toxicities After Irinotecan-Based Chemotherapy in a Patient With Lung Cancer: A Homozygote for the SLCO1B1*15 Allele2007
- Author(s)
  Takane, H, Miyata, M, Burioka, N, Kurai, J, Fukuoka, Y, Suyama, H, Shigeoka, Y, Otsubo, K, Ieiri, I, Shimizu, E
- Journal Title
  
  Ther Drug Monit 29
  
  Pages: 666-668
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Function of clock genes in disease: Influence of medication for bronchial asthma on circadian gene.2007
- Author(s)
  Burioka N, Fukuoka Y, Takata M, Endo M, Miyata M, Chikumi H, Tomita K, Kodani M, Touge H, Takeda K, Sumikawa T, Yamaguchi K, Ueda Y, Nakazaki H, Suyama H, Yamasaki A, Sano H, Igishi T, Shimizu E
- Journal Title
  
  J Pharmacol Sci 103(2)
  
  Pages: 144-149
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Dexamethasone inhibits paclitaxel-induced cytotoxic activity through retinoblastoma protein dephosphorylation in non-small cell lung cancer cells2007
- Author(s)
  Morita, M, Suyama, H, Igishi, T, Shigeoka, Y, Kodani, M, Hashimoto, K, Takeda, K, Sumikawa, T, Shimizu, E
- Journal Title
  
  Int J Oncol 30
  
  Pages: 187-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Diverse activation states of R_hoA in human lung cancer cells: contribution of G protein coupled receptors2007
- Author(s)
  Touge, H, Chikumi, H, Igishi, T, Kurai, J, Makino, H, Tamura, Y, Takata, M, Yoneda, K, Nakamoto, M, Suyama, H, Gutkind, JS, Shimizu, E
- Journal Title
  
  Int J Oncol 30
  
  Pages: 709-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma2006
- Author(s)
  Matsumoto, S, Takahashi, K, Iwakawa, R, Matsuno, Y, Nakanishi, Y, Kohno T, Shimizu, E, Yokota, J
- Journal Title
  
  Int J Cancer 119
  
  Pages: 1491-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma2006
- Author(s)
  Matsumoto, S, Iwalcawa, R, Kohno, T, Suzuki, K, Matsuno, Y, Yamamoto, S, Noguchi, M, Shimizu, E, Yokota, J
- Journal Title
  
  Int J Cancer 118
  
  Pages: 2498-504
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590849
[Journal Article] Dexamethasone influences human clock gene expression in bronchial epithelium and peripheral blood mononuclear cells in vitro2005
- Author(s)
  Burioka N, Takata M, Okano Y, Ohdo S, Fukuoka Y, Miyata M, Takane H, Endo M, Suyama H, Shimizu E
- Journal Title
  
  Chronobiol Int 22(3)
  
  Pages: 585-590
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Glucocorticoid administration increases hPer1 mRNA levels in human peripheral blood mononuclear cells in vitro or in vivo.2005
- Author(s)
  Fukuoka Y, Burioka N, Takata M, Ohdo S, Miyata M, Endo M, Shimizu E
- Journal Title
  
  J Biol Rhythm 20(6)
  
  Pages: 550-553
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] β2-adrenoceptor agonists induce the mammalian clock gene, hPer1, mRNA in cultured human bronchial epithelium cells in vitro.2005
- Author(s)
  Takata M, Burioka N, Ohdo S, Fukuoka Y, Miyata M, Endo M, Suyama H, Shimizu E
- Journal Title
  
  Chronobiol Int 22(4)
  
  Pages: 777-783
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Clock gene dysfunction in patients with obstructive sleep apnea syndrome.
- Author(s)
  Burioka N, Koyanagi S, Endo M, Takata M, Fukuoka Y, Miyata M, Takeda K, Chikumi H, Ohdo S, Shimizu E
- Journal Title
  
  Eur Respir J (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590791
[Journal Article] Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells Oncology reports
- Author(s)
  Miyake N, Chikumi H, Takata M, Nakamoto M, Igishi T, Shimizu E
- Volume
  (in press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22313637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] 骨芽細胞におけるResolvin E1のPGE2産生抑制効果とその機序についての検討2017
- Author(s)
  舟木佳弘、長谷川泰之、末田悠里子、原田智也、岡崎亮太、山崎章、清水英治
- Organizer
  第61回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] 滑膜線維芽細胞におけるω‐3系脂肪酸由来抗炎症脂質メディエーターの抗炎症効果やRANKL発現抑制効果についての検討2017
- Author(s)
  岡崎亮太、長谷川泰之、舟木佳弘、末田悠里子、原田智也、山崎章、清水英治
- Organizer
  第61回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] SMARCA4-deficient thoracic sarcomaに対して放射線治療が奏功した１例2017
- Author(s)
  武田賢一、桑本聡史、田原誉敏、田中那津美、矢内正晶、小谷昌広、牧野晴彦、山口耕介、坂本智宏、清水英治
- Organizer
  第26回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] トシリズマブ投与後にマクロファージ活性化症候群を発症し,自然軽快した成人発症スティル病の1例2017
- Author(s)
  末田悠里子、原田智也、舟木佳弘、岡崎亮太、長谷川泰之、山崎章、清水英治
- Organizer
  第61回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] Nivolumabで治療した非小細胞肺癌患者の中枢神経系転移2017
- Author(s)
  田中那津美、武田賢一、矢内正晶、牧野晴彦、泉大樹、井岸正、清水英治
- Organizer
  第26回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] 肺癌標的分子としてのULBP2の役割と治療戦略2016
- Author(s)
  清水英治
- Organizer
  第25回日本がん転移学会学術集会
- Place of Presentation
  米子コンベンションセンター（鳥取県米子市）
- Year and Date
  2016-07-22
- Invited
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] 肺癌細胞におけるEGFR阻害剤耐性獲得時の浸潤能とその機序の検討2014
- Author(s)
  高田美也子、泉大樹、千酌浩樹、三宅直美、牧野晴彦、井岸正、清水英治
- Organizer
  第23回日本がん転移学会総会
- Place of Presentation
  金沢市文化ホール（金沢）
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-26462755
[Presentation] 肺癌細胞におけるEGFR阻害剤耐性獲得時の浸潤能とその機序の検討2014
- Author(s)
  高田美也子、泉大樹、千酌浩樹、三宅直美、牧野晴彦、井岸正、清水英治
- Organizer
  第23回日本がん転移学会総会
- Place of Presentation
  金沢市文化ホール（金沢市）
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-26461159
[Presentation] Circulating serum ULBP2 in patients with various lung diseases2012
- Author(s)
  Kinoshita N, Chikumi H, Yamaguchi K, Takata M, Nakamoto M, Kodani M, Matsumoto S, Kawasaki Y, Tadashi I, Shimizu E
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2012-04-22
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Development of a novel combination therapy using cetuximab2012
- Author(s)
  Takata M, Chikumi H, Igishi T, Burioka N, Yamasaki A, Nakamoto M, Kinoshita N, Kitaura T, Okada K, Shimizu E
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Development of a novel combination therapy using cetuximab2012
- Author(s)
  Takata M, Shimizu E, et al
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] Antibody-dependent cellular cytotoxicity mediated by cetuximab against mesothelioma cells2010
- Author(s)
  Chikumi H, Kurai J, Kinoshita N, Nakamoto M, Matsumoto S, Igishi T, Hamada H, Yano S, Shimizu E
- Organizer
  The 10th international conference of the international mesothelioma interest group
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Antibody-dependent cellular cytotoxicity mediated by cetuximab against mesothelioma cells2010
- Author(s)
  Chikumi H, Kurai J, Kinoshita N, Nakamoto M, Matsumoto S, Igishi T, Hamada H, Yano S, Shimizu E
- Organizer
  The 10th international conference of the international mesothelioma interest group(Workshop : Immunotherapy : bench to bedside-II)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] Soluble UL16 binding protein 2 is elevated in the sera of lung cancer patients2010
- Author(s)
  Yamaguchi K, Chikumi H, Kinoshita N, Shimizu A, Hashimoto K, Kurai J, Yamasaki A, Nakamoto M, Matsumoto S, Takata M, Igishi T, Burioka N, Shimizu E
- Organizer
  American Association for Cancer Research 101st Annual Meeting 2010
- Place of Presentation
  Washington DC, USA
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21590994
[Presentation] Antibody-Dependent Cellular Cytotoxicity Mediated by Cetuximab against Mesothehoma Cells.2010
- Author(s)
  H.Chikumi, E.Shimizu.
- Organizer
  The 101th International Conference of the International Mesothelioma Interest Group.
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590863
[Presentation] Biomarkers of immunological therapy of lung cancer2009
- Author(s)
  Chikumi, H., Shimizu, E
- Organizer
  第49回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-21590994

1. CHIKUMI Hiroki (90283994)

# of Collaborated Projects: 7 results

# of Collaborated Products: 27 results
2. BURIOKA Naoto (50252854)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. YAMAGUCHI Kousuke (60529402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. MIYAKE Naomi (90747205)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. YOSHIZUMI Masanori (60294667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HOUCHI Hitoshi (00219156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 高田美也子 (50523643)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
8. 山本晃義 (60284288)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KINOSHITA Naoki (40750336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWANISHI Masashi (90301316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MORIGUCHI Satoru (80166397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MINAKUCHI Kazuo (30284326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IKEHARA Toshitaka (40111033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YASUDA Kazuhito (90322213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IGISHI Tadashi (80273895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KISHIMOTO Takuji (00116394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OZAKI Toshio (70108893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 曽根三郎 (40145024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 篠原勉 (70284289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 西岡安彦 (70274199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 楊河宏章 (50263827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 高橋安毅 (10253197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMIZU EIJI 清水 英治

SHIMIZU Eiji 清水 英治

Research Projects

Research Products

Co-Researchers

Development of the new clinical cure to overcome pemetrexed tolerance for malignant pleural mesotheliomaPrincipal Investigator

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Development of novel therapy for malignant mesothelioma by controllingADCC activity.Principal Investigator

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Measurement of newly developed tumor markers and molecular markers in health screening for lung cancerPrincipal Investigator

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Measurement of antibodies against tumor suppressor gene products in health screening for lung cancerPrincipal Investigator

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Gene therapy for lung cancer using tumor suppressor gene product as molecular targetPrincipal Investigator

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Basic and clinical research of peripheral blood stem cell transplant (PBSCT) in chemotherapy for lung cancerPrincipal Investigator

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SHIMIZU EIJI 清水英治

SHIMIZU Eiji 清水英治