HAYASHI Yoshitake 林祥剛

Researcher Number	50189669
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009 – 2021: 神戸大学, 保健学研究科, 教授 2013: 神戸大学, 大学院保健学研究科, 教授 2010: 神戸大学, 大学院・保健学研究科, 教授 2002 – 2008: Kobe University Neurosurgery Prof., 医学部, 教授 2001 – 2002: 神戸大学, 大学院・医学系研究科, 助教授 1993 – 2000: 神戸大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Human pathology / Human pathology / Epidemiology and preventive medicine Except Principal Investigator Thoracic surgery / Cerebral neurosurgery / Gastroenterology / Basic Section 49050:Bacteriology-related / Cerebral neurosurgery / Thoracic surgery / Respiratory surgery / Digestive surgery
Keywords	Principal Investigator HNF-1 / 肝細胞癌 / Hepatocellular carcinoma / Oval cell / HNF-4 / 人体病理 / 転写制御因子 / vHNF-1 / FoxO1 / Akt … More / PI3-kinase / SgIGSF / 糖尿病 / Nonalcoholic steatohepatitis (NASH) / oval cell / HNF / SAP-1 / HNF-3 / Pathology / Stem cell / Nuclear protein / Transcriptional regulation factor / 病理 / 組織病理学 / インターフェロン / Fox01 / インスリン抵抗性 / NASH / 予防医学 / 疫学 / 教育活動 / 疫学調査 / 画像診断 / B型肝炎ウイルス / 教育 / 肝疾患 / インドネシア国 / 医学 / 薬剤耐性 / 早期診断 / 肝がん / 肝炎ウイルス / インドネシア / Insulin resistance / Diabetes Mellitus / Regenerative medicine / Hepatocyte / 骨髄幹細胞 / 遺伝子多型 / HCV / HBV / 肝臓 / 再生医学 / 肝細胞 / Fatty change of liver / Hepatic stemcell / Regeneration / ATBF-1 / 2-acetylaminofluorene(2-AAF) / tyrosine phosphatase / 劇症肝炎 / _p27^<Kip1> / hepatocyte nuclear factor / apoptosis / 肝脂肪化 / 肝幹細胞 / 幹細胞 / 肝再生 / Tyrosine phosphatase / Transcription factor / E-cadherin / HNF-6 / liver / differentiation / pathology / transcriptional regulation / gene therapy / hepatocellular carcinoma / Histology / HCC / Transcription / Liver / uPAR / uPA / Differentiation / RT-PCR / competitive RT-PCR / 転写抑制因子 / 組織分化 / 免疫染色 / 核蛋白 / 転写因子 / 組織診断 / 分化 / Human Pathology / Histopathology / Hepatoblastoma / Competitive RT-PCR / 転写制御 / Competetive RT-PCR / 肝芽腫 / CompetetiveRT-PCR / 血管内皮リパーゼ / adipocytokine / アルコール性肝炎 / 脂肪肝 / メタボリック症候群 / Nonalcoholic steatohepatitis(NASH) / pegylated interferon / cryptogenic cirrhosis / 非B非C肝炎 / 酸化ストレス / 非ウイルス性肝癌 / 非ウイルス性肝炎 / アディポネクチン / Endothelial lipase / 脂肪性肝炎 … More Except Principal Investigator VEGF / 原発性肺癌 / 肺癌 / 遺伝子治療 / 悪性グリオーマ / SAP-1 / lung cancer / 癌宿主相互作用 / 腫瘍血管新生 / アンチセンス / 重粒子線 / 腫瘍マーカー / チロシンホスファターゼ / 脂肪性肝炎 / 非アルコール性脂肪性肝炎 / 腸内細菌 / 脂肪性肝疾患 / 高脂肪食 / Bacteroides / 短鎖脂肪酸 / 脂肪肝 / single nucleotide polymorphism / DNA damage repair gene / risk factor / 1塩基多型 / DNA修復遺伝子 / 危険因子 / hRad9 / DNA damage / 細胞周期 / DNA複製 / Rad9 / DNAダメージ / gene therapy / angiogenesis / radiotherapy / brain tumor / 血管新生阻止療法 / 重粒子線治療 / 血管新生 / 放射線治療 / 脳腫瘍 / Anti-angiogenic Gene Therapy / Antisense / Malignant Gliomas / デコイ / HIF-1 / siRNA / RNA干渉 / ウイルス産生細胞 / Inhibitor / Antibody / Gastrointestinal cancer / Protein tyrosine phosphatse / CEA / モノクローナル抗体 / チロシンガスファターゼ / 阻害剤 / 抗体 / 消化器癌 / テロシンホスファターゼ / apotosis / myocardial protection / myocardial ischemia / 高齢心筋 / 心筋虚血障害 / アポトーシス / 心筋保護 / 心筋虚血 / 癌幹細胞 / トランスレーショナルリサーチ / バイオテクノロジー / 発生・分化 / lung cancer organoids / iPS cell / cancer stem cell / cancer invasion / adenocaricinoma / lung cancerr / 癌浸潤 / Necl-5 / バイオマーカー / 分子標的 / 上皮間葉移行 / 浸潤能 / Necl5 / 細胞接着分子 / 肺腺癌 / 線維芽細胞 / 線維芽細 / 浸潤 / 呼吸器外科学 / 炭素線 / 遺伝子診断 / 肝特異転写因子 / 肝細胞癌 / CL100 / 胃癌 / 大腸癌 Less

Effect for Bacteroides spp. against steatohepatitis
- Principal Investigator
  
  Yano Yoshihiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kobe University
Establishment of the education system to the early diagnosis of the chronic liver disease in IndonesiaPrincipal Investigator
- Principal Investigator
  
  Hayashi Yoshitake
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Kobe University
The Role of induced lung cancer stem Like cells on invasive activity of lung adenocaricinoma
- Principal Investigator
  
  MANIWA YOSHIMASA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kobe University
The role of Necl-5 in the invasive activity of lung adenocarcinoma
- Principal Investigator
  
  MANIWA YOSHIMASA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kobe University
The role of cancer-host interaction in the invasion of lung adenocarcinoma
- Principal Investigator
  
  MANIWA Yoshimasa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kobe University
肝炎ウイルス非感染肝細胞癌発生の分子機序の解明Principal Investigator
- Principal Investigator
  
  林祥剛
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kobe University
Non-synonymous SNPs of DNA damage repair genes in lung cancer patients
- Principal Investigator
  
  MANIWA Yoshimasa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kobe University
The differentiating regulation from bone marrow stem cells and hepatic stem cells to hepatocytes and bile-duct cells as a tool of treatment against hepatic failurePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshitake
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kobe University
Significance of hRad9 expression in non-small cell lung cancer cells
- Principal Investigator
  
  MANIWA Yoshimasa
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kobe University
Basic research for the combination with anti-angiogenic therapy and heavy charged particle therapy against malignant gliomas
- Principal Investigator
  
  EHARA Kazumasa
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kobe University
Identification and characterization of the phenotype of hepatic stem cells in various liver diseases, its application to frontier medicinePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshitake
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kobe University
重粒子線と血管新生阻止療法を併用した悪性神経膠腫の局所制御に関する基礎的研究
- Principal Investigator
  
  EHARA Kazumasa
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kobe University
Antisense VEGF Tumor Gene Therapy for Malignant Gliomas (Anti-angiogenic Gene Therapy)
- Principal Investigator
  
  SASAKI Masato
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kobe University Graduate School of Medicine
Analysis of expressional changes of liver enriched transcription factors during occurrence and development of hepatocellular carcinoma, its application to pathological diagnosis and gene therapyPrincipal Investigator
- Principal Investigator
  
  YOSHITAKE Hayashi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human pathology
- Research Institution
  Kobe University
肝細胞癌の肝特異転写因子発現比による診断法の研究
- Principal Investigator
  
  山本正博
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Basic research and clinical application of SAP-1, a protein tyrosine phosphatase expressed in gastrointestinal cancers.
- Principal Investigator
  
  MATOZAKI Takashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
消化器癌におけるチロシンホスファターゼの異常に関する研究
- Principal Investigator
  
  MATOZAKI Takashi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
Analysis of how liver-specific transcriptional regulation factors are implicated in hepatocytic differentiation and oncogenesis ; their application for histo- and clinicopathological diagnosisPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshitake
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  KOBE UNIVERSITY
Induction of apotosis in ischemic and reperfused rabbit heart
- Principal Investigator
  
  ATAKA Keiji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kobe University
THE ROLE OF TRANSCRIPTIONAL REGULATION FACTORS ON ONTOGENY,DIFFERENTIATION AND ONCOGENESIS ; ITS APPLICATION FOR HISTOPATHOLOGIC DIAGNOSISPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshitake
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  KOBE UNIVERSITY

All 2021 2019 2018 2017 2016 2013 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Clinical features of immune-mediated hepatotoxicity induced by immune checkpoint inhibitors in patients with cancers.2021
- Author(s)
  Yamamoto A, Yano Y, Ueda Y, Yasutomi E, Hatazawa Y, Hayashi H, Yoshida R, Asaji N, Shiomi Y, Tobimatsu K, Sakai A, Kodama Y.
- Journal Title
  
  J Cancer Res Clin Oncol.
  
  Volume: 147 Issue: 6 Pages: 1747-1756
- DOI
  10.1007/s00432-020-03448-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07539
[Journal Article] Analysis of hepatitis B virus genotype and gene mutation in patients with advanced liver disease in East Kalimantan, Indonesia2019
- Author(s)
  Wahyuni RM, Utsumi T, Juniastuti, Yano Y, Murti IS, Amin M, Yamani LN, Istimagfiroh A, Purwono PB, Soetjipto, Lusida MI, Hayashi Y
- Journal Title
  
  Biomedical Reports
  
  Volume: 10 Pages: 303-310
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Association Between HBx Variations and Development of Severe Liver Disease Among Indonesian Patients2019
- Author(s)
  Putri WA, Yano Y, Yamani LN, Lusida MI, Soetjipto, Liang Y, Mardian Y, Wasityastuti W, Hayashi Y
- Journal Title
  
  Kobe J Med Sci
  
  Volume: 65
- NAID
  120006645703
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Association between quasispecies variants of hepatitis B virus, as detected by high throughput sequencing, and progression of advanced liver disease in Indonesian patients2019
- Author(s)
  Putri WA, Yano Y, Yamani LN, Liang Y, Mardian Y, Utsumi T, Soetjipto, Lusida MI, Hayashi Y.
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection2018
- Author(s)
  Hatazawa Yuri、Yano Yoshihiko、Okada Rina、Tanahashi Toshihito、Hayashi Hiroki、Hirano Hirotaka、Minami Akihiro、Kawano Yuki、Tanaka Motofumi、Fukumoto Takumi、Murakami Yoshiki、Yoshida Masaru、Hayashi Yoshitake
- Journal Title
  
  Infectious Agents and Cancer
  
  Volume: 13 Issue: 1 Pages: 1-8
- DOI
  10.1186/s13027-018-0179-4
- NAID
  120006398795
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19328, KAKENHI-PROJECT-16H05826
[Journal Article] Early changes in quasispecies variant after antiviral therapy for chronic hepatitis B.2018
- Author(s)
  Liang Y, Yano Y, Putri WA, Mardian Y, Okada R, Tanahashi T, Murakami Y, Hayashi Y.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 17 Pages: 5528-5537
- DOI
  10.3892/mmr.2018.8551
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Genetic polymorphisms of HLA-DP and isolated anti-HBc are important subsets of occult hepatitis B infection in Indonesian blood donors: a case-control study.2017
- Author(s)
  Mardian Y, Yano Y, Wasityastuti W, Ratnasari N, Liang Y, Putri WA, Triyono T, Hayashi Y.
- Journal Title
  
  Virol J.
  
  Volume: 14 Issue: 1 Pages: 1-11
- DOI
  10.1186/s12985-017-0865-7
- NAID
  120006373794
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Profile of Mutations in the Reverse Transcriptase and Overlapping Surface Genes of Hepatitis B Virus (HBV) in Treatment-Naïve Indonesian HBV Carriers2017
- Author(s)
  4.Yamani LN, Yano Y, Utsumi T, Wasityastuti W, Rinonce HT, Widasari DI, Juniastuti, Lusida MI, Soetjipto, Hayashi Y.
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 70 Issue: 6 Pages: 647-655
- DOI
  10.7883/yoken.JJID.2017.078
- NAID
  130006210251
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Hepatitis B Virus Infection in Indonesia 15 Years after Adoption of a Universal Infant Vaccination Program: Possible Impacts of Low Birth Dose Coverage and a Vaccine-Escape Mutant.2016
- Author(s)
  2.Purwono PB, Juniastuti, Amin M, Bramanthi R, Nursidah, Resi EM, Wahyuni RM, Yano Y, Soetjipto, Hotta H, Hayashi Y, Utsumi T, Lusida MI.
- Journal Title
  
  Am J Trop Med Hyg.
  
  Volume: 95 Issue: 3 Pages: 674-679
- DOI
  10.4269/ajtmh.15-0121
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Protective effects of HLA-DPA1/DPB1 variants against Hepatitis B virus infection in an Indonesian population.2016
- Author(s)
  3.Wasityastuti W, Yano Y, Ratnasari N, Triyono T, Triwikatmani C, Indrarti F, Heriyanto DS, Yamani LN, Liang Y, Utsumi T, Hayashi Y.
- Journal Title
  
  Infect Genet Evol.
  
  Volume: 41 Pages: 177-184
- DOI
  10.1016/j.meegid.2016.03.034
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Journal Article] Slug increases sensitivity to tubulin-binding agents via the downregulation ofβIII andβIVa-tubulin in lung cancer cells2013
- Author(s)
  Tamura D, Arao T, Nagai T, Kaneda H, Aomatsu K, Fujita Y, Matsumoto K, De Velasco MA, Kato H, Hayashi H, Yoshida S, Kimura H, Maniwa Y, Nishio W, Sakai Y, Ohbayashi C, Kotani Y, Nishimura Y, Nishio K.
- Journal Title
  
  Cancer Med
  
  Volume: 2 Pages: 144-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592060
[Journal Article] Psf3 is a prognostic biomarker in lung adenocarcinoma2013
- Author(s)
  Hokka D, Maniwa Y, Tane S, Nishio W, Yoshimura M, Okita Y, Ohbayashi C, Sakai Y, Chen X, Hayashi Y
- Journal Title
  
  Ｌｕｎｇ　Ｃａｎｃｅｒ
  
  Volume: ７９ Issue: 1 Pages: 77-82
- DOI
  10.1016/j.lungcan.2012.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592060
[Journal Article] Psf3 is a prognostic biomarker in lung adenocarcinoma2013
- Author(s)
  Hokka D, Maniwa Y, Tane S, Nishio W, Yoshimura M, Okita Y, Ohbayashi C, Sakai Y, Chen X, Hayashi Y
- Journal Title
  
  Lung Cancer
  
  Volume: 79 Pages: 77-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592060
[Journal Article] Slug increases sensitivity to tubulin-binding agents via the downregulation of βIII and βIVa-tubulin in lung cancer cells2013
- Author(s)
  Tamura D, Arao T, Nagai T, Kaneda H, Aomatsu K, Fujita Y, Matsumoto K, De Velasco MA, Kato H, Hayashi H, Yoshida S, Kimura H, Maniwa Y, Nishio W, Sakai Y, Ohbayashi C, Kotani Y, Nishimura Y, Nishio K
- Journal Title
  
  Cancer Med
  
  Volume: ２ Issue: 2 Pages: 144-154
- DOI
  10.1002/cam4.68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592060, KAKENHI-PROJECT-24240122, KAKENHI-PROJECT-25350979
[Journal Article] The Oncogenic Phosphatase Wip1 is a Novel Prognostic Marker for Lung Adenocarcinoma Patient Survival2011
- Author(s)
  Satoh N, Maniwa Y*, Bermudez VP, Nishimura K, Nishio W, Yoshimura M, Okita Y, Ohbayashi C, Hurwitz J, Hayashi Y
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1101-1109
- NAID
  10029294028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592060
[Journal Article] MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell2011
- Author(s)
  Doi T, Maniwa Y*, Tanaka Y, Tane S, Hashimoto S, Ohno Y, Nishio W, Nishimura Y, Ohbayashi C, Okita Y, Hayashi Y, Yoshimura M.
- Journal Title
  
  Exp Mol Pathol
  
  Volume: 90 Pages: 91-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592060
[Journal Article] Non-synonymous SNPs in DNA damage repair pathways and lung cancer risk.2010
- Author(s)
  Tanaka Y, Maniwa Y, Bermudez VP, Doi T, Nishio W, Ohbayashi C, Okita Y, Hurwitz J, Hayashi Y, Yoshimura M.
- Journal Title
  
  Cancer 116
  
  Pages: 896-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591670
[Journal Article] Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma.2010
- Author(s)
  Nakai R, Maniwa Y, Tanaka Y, Nishio W, Yoshimura M, Okita Y, Ohbayashi C, Satoh N, Ogita H, Takai Y, Hayashi Y
- Journal Title
  
  Cancer Sci 101
  
  Pages: 1326-1330
- NAID
  10026592945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591670
[Journal Article] The cytological characteristics of small cell change of dysplasia in small hepatic nodules.2010
- Author(s)
  Chang O, Yano Y, Masuzawa A, Fukushima N, Teramura K, Hayashi Y.
- Journal Title
  
  Oncol Rep 23
  
  Pages: 1229-1232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591670
[Journal Article] Clinical significance of hepatitis B virus-DNA in hepatocellular carcinoma negative for hepatitis B virus surface antigen.2010
- Author(s)
  Tateiwa S, Yano Y, Seo Y, Miki A, Kawano Y, Azuma T, Hayashi Y.
- Journal Title
  
  Exper Therapeutic Med 1
  
  Pages: 343-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591670
[Journal Article] Expression and localization of FOXO1 in non-small cell lung cancer.2009
- Author(s)
  Maekawa T, Maniwa Y, Doi T, Okada K, Nishio W, Yoshimura M, Ohbayashi C, Hayashi Y, Okita Y.
- Journal Title
  
  Oncol Rep 22
  
  Pages: 57-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591670
[Journal Article] damage sensor protein hRad9-a novel molecular target for lung cancer treatment2008
- Author(s)
  Yuki, T, Maniwa, Y*, Doi, T, Okada, K, Nishio, W, Hayashi, Y, Okita, Y., DNA
- Journal Title
  
  Dncol Rep (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591547
[Journal Article] Double-layered collagen gel hemisphere for cell invasion assay: Successful visualization and quantification of cell invasion activity2007
- Author(s)
  Takata, M, Maniwa, Y*, Doi, T, Tanaka, Y, Okada, K, Nishio, W, Ohbayashi, C, Yoshimura, M, Hayashi, Y, Okita, Y
- Journal Title
  
  Cell common adhes 14
  
  Pages: 157-167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591547
[Journal Article] MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell.
- Author(s)
  Doi T, Maniwa Y, Tanaka Y, Tane S, Hashimoto S, Ohno Y, Nishio W, Nishimura Y., Ohbayashi C, Okita Y, Hayashi Y, Yoshimura M.
- Journal Title
  
  Exp Mol Pathol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591670
[Presentation] A crude extract from Cananga odorata exhibits antiviral activity against hepatitis B virus2019
- Author(s)
  Indrasetiawan Puguh, 靭千恵, Muhammad Hanafi, Sri Hartata, 亀岡正典, 堀田博, 林祥剛
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05826
[Presentation] 進行肝疾患おけるHBVウイルス多様性の変化－インドネシア人の次世代シークエンサーを用いた解析から2018
- Author(s)
  矢野嘉彦、林宏樹、安冨栄一郎、畑澤友里、平野仁崇、南晶洋、川野佑輝、林祥剛
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H05826
[Presentation] Profile of HBx variation in relation to HCC development among Indonesian patients2018
- Author(s)
  Putri W Aristyaning, 矢野嘉彦, Yamani N Laura, Maria I Lusida, Soetjipto, Yujiao Liang, Yan Mardian, 林祥剛
- Organizer
  The 25th APASL Single Topic Conference on HCC Yokohama
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Presentation] Reduced muscle (radio) density and Barcelona Clinic Liver Cancer (BCLC) staging are independently survival prognostic of Indonesia hepatocellular carcinoma (HCC) patients2018
- Author(s)
  Mardian Yan, Yoshihiko Yano, Neneng Ratnasari, Lina Choridah, Fahmi Indrati, Putut Bayupurnama, Catharina Triwikatwani, Nurhuda H Setiawan, Yoshitake Hayashi
- Organizer
  Internatinal Digestive Disease Forum (IDDF) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826
[Presentation] A Comparison of Quasispecies Variant of Pre-S/S Gene in HBV-related HCC with HBs Antigen Positive and Occult Infection2018
- Author(s)
  畑澤友里、岡田理奈、棚橋俊仁、林宏樹、平野仁崇、南晶洋、川野佑輝、田中基文、福本巧、村上善基、吉田優、林祥剛
- Organizer
  The 25th APASL Single Topic Conference on HCC Yokohama
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05826

1. MANIWA Yoshimasa (50362778)

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# of Collaborated Products: 12 results
2. MATOZAKI Takashi (80252782)

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3. KANOMATA Naoki (60263373)

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4. Yano Yoshihiko (60419489)

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5. SASAKI Masato (80314483)

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6. EHARA Kazumasa (20151996)

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7. GU Eisei (40195615)

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8. SUGIMURA Kazurou (00136384)

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9. HANIOKA Keisuke (70127463)

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10. ITOH Hiroshi (40168373)

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11. SANO Kimihiko (40205993)

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12. SEO Yasushi (90362772)

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13. YOSHIMURA Masahiro (70324910)

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14. OKITA Yutaka (40322193)

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15. OBAYASHI Chiho (90223940)

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16. SAIJOH Kiyofumi (00178469)

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17. ATAKA Keiji (20252760)

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18. YAMASHITA Chojiro (00144569)

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19. KITAGAWA Motoji (80262898)

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20. TAKEYAMA Yoshifumi (70263374)

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21. AOYAMA Nobuo (30243299)

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22. TAMAKI Norihiko (10030941)

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23. KOHMURA Eiji (30225388)

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24. KAWAMURA Atsufumi (00346256)

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25. SASAYAMA Takashi (10379399)

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26. TSUJIMURA Tohru (20227408)

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27. 山本正博 (40166822)

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28. 福本巧 (70379402)

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29. 青井貴之 (00546997)

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30. 穀内隆 (30178248)

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31. 尹聖哲 (60273786)

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32. 靭千恵 (50570834)

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33. 亀岡正典 (60281838)

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34. 星奈美子 (40645214)

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35. TSUKUBE Takuro

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36. NAKAJIMA Motoo

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37. 金丸太一

# of Collaborated Projects: 1 results

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38. LUSIDA Maria Inge

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
39. RATNASARI Neneng

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
40. MUHAMMAD Hanafi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
41. 川野佑輝

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# of Collaborated Products: 1 results

HAYASHI Yoshitake 林 祥剛

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Establishment of the education system to the early diagnosis of the chronic liver disease in IndonesiaPrincipal Investigator

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肝炎ウイルス非感染肝細胞癌発生の分子機序の解明Principal Investigator

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The differentiating regulation from bone marrow stem cells and hepatic stem cells to hepatocytes and bile-duct cells as a tool of treatment against hepatic failurePrincipal Investigator

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Identification and characterization of the phenotype of hepatic stem cells in various liver diseases, its application to frontier medicinePrincipal Investigator

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Analysis of expressional changes of liver enriched transcription factors during occurrence and development of hepatocellular carcinoma, its application to pathological diagnosis and gene therapyPrincipal Investigator

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HAYASHI Yoshitake 林祥剛