FUJII Teruhiko 藤井輝彦

… Alternative Names

藤井輝彦フジイテルヒコ

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Researcher Number	50199288
External Links
Affiliation (Current)	2025: 久留米大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2007 – 2014: Kurume University, Dept of Medicine, Associated Professor 2003 – 2007: KURUME UNIVERSITY, SCHOOL OF MEDICINE, ASSISTANT PROFESSOR, 医学部, 講師 2006: Kurume University, Medical School, Associate Professor, 医学部, 助教授 2001 – 2004: 久留米大学, 医学部, 助手 2000: 久留米大学, 医学部, 講師 … More 1996 – 1997: 久留米大学, 医学部, 助手 1994: 医学部, 助手 1992 – 1994: 久留米大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General surgery / Digestive surgery Except Principal Investigator Digestive surgery / Radiation science / General surgery / Orthopaedic surgery / 細胞生物学 / Radiation science
Keywords	Principal Investigator Cap43 / YB-1 / breast cancer / 薬剤耐性 / ER / NDRG1 / HER2 / Akt / ER-α / 乳癌 … More / b2 chimaerin / protein kinase C / esophageal cancer / β2chimaerin / protein kinase C(PKC) / chimaerin / protein kinase C (PKC) / 食道癌 … More Except Principal Investigator Prospective trial / Informed consent / 乳癌 / 癌 / MAPK / 食道癌 / siRNA / ERK MAPK / 骨転移 / monoclonal antibody MIB-1 / 細胞増殖 / ERK / Induction chemoradiotherapy / Esophageal cancer / Area under the curve (AUC) / 導入照射化学療法 / 集学的治療 / 局所進行癌(T4) / Fab / 免疫 / PET/CT / 免疫学 / 乳腺外科学 / vitamin D_3 / differentiation / Cap 43 / osteosarcoma / 転移 / ビタミンD3 / 分化 / Cap43 / 骨肉腫 / Prognosis of patients with breast cancer / Cell proliferation / Breast cancer / 乳癌患者の予後予測 / signal transduction / breast cancer / bone metastasis / 動物実験モデル / 細胞内情報伝達 / atherosclerosis / phenotypes / protein kinase C / beta2-chimaerin / smooth muscle, vascular / プロテインキナーゼ C / 動脈硬化 / 形質転換 / プロテインキナーゼC / β2-カイメリン / 血管平滑筋細胞 / thyroid papillary carcinoma / cancer cell proliferation / cell cycle / ^<201>Tl / lung neoplasm / Non-small cell carcinoma / Small cell lung carcinoma / 核医学トレーサ / lung carcinoma / p-53 / MRP / mdr-1 gene product / Tc-99mSestamibi / EPK / Tc-99m Sestamibi / MIB-1 / 細胞増殖機能 / Tl-201 / 肺癌 / Hyperfruction radiotherapy / Daily chemotherapy / Multimodal treatment / Locally-advanced (T4) cancer / 術前照射化学療法 / 超多分割照射 / 制癌剤少量連日投与 / daily low-dose CTx / Multimodality treatment / Locally advanced cancer (T4) / インフォームドコンセント / シスプラチン(CDDP) / 化学療法 / AUC / インフォームド・コンセント / 姑息切除 / 制癌剤治療 / 放射線治療 / 局所進行癌 / Area under the curve(AUC) / Prospective trrial / 制癌剤少量連日投与法 / Tumor imaging / Biodistribution / F[ab']2 / Monoclonal antibody / Esophageal carcinoma / F(ab)'2 / F(ab′)_2フラグメント / 腫瘍イメージング / 生体内分布 / Fabフラグメント / F(ab')_2フラグメント / モノクローナル抗体 / 食道扁平上皮癌 / シグナル伝達 / 分子病理 / 膵臓癌 / 分子病理学 / 膵臓 / Akt / GLUT 4 / GLUT3 / GLUT1 / GLUT Family / GLUT 3 / GLUT 1 / VEGF / GLUT family / FDG / CT / PET Less

乳癌における分子標的治療薬に対する薬剤耐性機構の解明Principal Investigator
- Principal Investigator
  
  藤井輝彦
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Study of immunosuppressive tumor microenvironment and therapeutic strategy in breast cancer
- Principal Investigator
  
  SEKI Naoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
The investigation of both FDG uptake mechanism and predicton prognosis using PET/CT in pancreatic cancer patients
- Principal Investigator
  
  ISHIBASHI Masatoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kurume University
Immunological study of HER2+breast cancer-study of strategy for effective cancer-immunotherapy
- Principal Investigator
  
  SEKI Naoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Molecular pathological evaluation of therapeutic effect using PET/CT in patients with esophageal cancer
- Principal Investigator
  
  ISHIBASHI Masatoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kurume University
Immunological effects of the treatment with anti-tumor monoclonal antibody in breast cancer patients
- Principal Investigator
  
  SEKI Naoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Suppression of metastasis in osteosarcoma by approaching molecular targets
- Principal Investigator
  
  HIRAOKA Koji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Cellular characteristics and clinical assessment of breast cancer using F-18 FDG-PET
- Principal Investigator
  
  ISHIBASHI Masatoshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kurume University
Study of drug sensitivity to molecular targeting drugs in breast cancerPrincipal Investigator
- Principal Investigator
  
  FUJII Teruhiko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Control of bone metastasis of breast cancer via intracellular signal transduaction.
- Principal Investigator
  
  ZEMMYO Michihisa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Role of protein kinase C and chimaerin in esophageal cancer cellsPrincipal Investigator
- Principal Investigator
  
  FUJII Teruhiko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kurume University
Analysis of the Beta2-chimaerin signaling in phenotypiC modulation of vascular smooth muscle cells
- Principal Investigator
  
  KATO Seiya
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞生物学
- Research Institution
  Kurume University
The analysis and clinical application cellular characteristics of lung carcinoma or thyroid cancer using radionuclide tracer
- Principal Investigator
  
  ISHIBASHI Masatoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KURUME UNIVERSITY
Study on multimodal treatment for a locally-advanced esophageal cancer. Surgery, is it necessary?
- Principal Investigator
  
  FUJITA Hiromasa
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KURUME UNIVERSITY
Study on Multimodality treatment for Locally Advanced Esophageal Cancer
- Principal Investigator
  
  FUHITA Hiromasa
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kurume University
Fundamental Studies on New Effective Diagnosis and Treatment for Esophageal Carcinomas by using Monoclonal Antibody and its Fragment.
- Principal Investigator
  
  IRIE Hitoshi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kurume University

All 2014 2013 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Feasibility study of personalized peptide vaccination for metastatic recurrent triple-negative breast cancer patients.2014
- Author(s)
  Takahashi R, Toh U, Iwakuma N, Takenaka M, Otsuka H, Furukawa M, Fujii T, Seki N, Kawahara A, Kage M, Matsueda S, Akagi Y, Yamada A, Itoh K, Sasada T.
- Journal Title
  
  Breast Cancer Res.
  
  Volume: 16 Issue: 4 Pages: 00-00
- DOI
  10.1186/bcr3685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591914, KAKENHI-PROJECT-24591925, KAKENHI-PROJECT-26293293, KAKENHI-PROJECT-26430176, KAKENHI-PROJECT-26461965
[Journal Article] Treatment outcome in patients with stage III breast cancer treated with neoadjuvant chemotherapy.2013
- Author(s)
  Takahashi R, Toh U, Iwakuma N, Mishima M, Fujii T, Takenaka M, Koura K, Seki N, Kawahara A, Kage M, Ogo E, Shirouzu K
- Journal Title
  
  Exp Ther Med
  
  Volume: 6 Pages: 1089-1095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591925
[Journal Article] Preclinical ,clinical studies of novel drugs for breast cancer Preclinical, clinical studies of novel drugs for breast cancer2008
- Author(s)
  Fujii T, et. al.
- Journal Title
  
  Curr Med Chem (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591304
[Journal Article] Clinicopathological study of invasive ductal carcinoma with large central acellular zone: Special reference to magnetic resonance imaging findings.2008
- Author(s)
  Yamaguchi R, Fujii T, et. al.
- Journal Title
  
  Pathol Int 58
  
  Pages: 26-30
- NAID
  10027375400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591304
[Journal Article] Expression of ErbB2/HER2 and Expression of ErbB2/HER2 and Y-box binding protein-i in human breast cancers2008
- Author(s)
  Fujii T, Yamana H, et. al.
- Journal Title
  
  Cancer Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591304
[Journal Article] 17b-Estradiol induces down-regulation of Cap43/NDRG1/Drg-l, a putative differentiation-related ,metastasis suppressor gene, in human breast cancer cells.2006
- Author(s)
  Fotovati A, Fujii T, et. al.
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 3010-3018
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591304
[Journal Article] 17P-Estradiol Induces Down-regulation of Cap43/NDRG1/Drg-1, a Putative Differentiation-related and Metastasis Suppressor Gene, in Human Breast Cancer Cells.2006
- Author(s)
  Fotovati A, Fujii T, Yamaguchi M, Kage M, Shirouzu K, Oie S, Basaki Y, Ono M, Yamana H, Kuwano M.
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 3010-3018
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591282
[Journal Article] Activation of protein Kinase C δ induces growth arrest in NPA thyroid cancer cells through extracellular signal-regulated kinase mitogen-activated protein kinase.2006
- Author(s)
  Koike K, Fujii T, Nakamura AM, Yokoyama G, Yamana H, Kuwano M, Shirouzu K.
- Journal Title
  
  Thyroid 16
  
  Pages: 333-341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591282
[Journal Article] Characterization of IL-2-activated TILs and their use for Intrapericardial Immunotherapy in Malignant Pericardial Effusion.2006
- Author(s)
  Toh U, Fujii T, Seki N, Niiya F, Shirouzu K, Yamana H.
- Journal Title
  
  Cancer Immunol Immun 55
  
  Pages: 1219-1227
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591282
[Journal Article] Her2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.2005
- Author(s)
  Hirata A, Hosoi F, Miyagawa M, Ueda S, Naito S, Fujii T, Kuwano M, Ono M.
- Journal Title
  
  Cancer Res 65
  
  Pages: 4253-4260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591282
[Journal Article] Sensitivity to Gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the EGF receptor/ERK1/2 and EGF receptor/Akt pathway for proliferation.2004
- Author(s)
  Ono M, Hirata A, Kometani T, Miyagawa M, Ueda S, Kinoshita H, Fujii T, Kuwano M.
- Journal Title
  
  Mol Cancer Ther 3
  
  Pages: 465-472
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591282
[Journal Article] The role of nuclear Y-box binding protein 1 as a global marker in drug resistance.2004
- Author(s)
  Kuwano M, Oda Y, Izumi H, Yang SJ, Uchiumi T, Iwamoto Y, Toi M, Fujii T, Yamana H, Kinoshita H, Kamura T, Tsuneyoshi M, Yasumoto K, Kohno K.
- Journal Title
  
  Mol Cancer Ther 3
  
  Pages: 1485-1492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591282
[Presentation] Strategy to augment the efficacy of immunotherapy for refractory breast cancer using trastuzumab combined adoptive cell therapy.2008
- Author(s)
  U. Toh, T. Fujii, N. Seki, S. Nakagawa, M. Mishima, M. Fukunaga, E. Ogo, T. Yahara, H. Yamana, K. Shirouzu
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago, IL, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591524
[Presentation] Combination of gemcitabine and adoptive cell therapy of autologous anti-tumor CTL induces clinical activities in patients with refractory lung cancer.2007
- Author(s)
  U. Toh, T. Fujii, S. Takamori, M. Fukunaga, E. Ogo, N. Seki, H. Yamana, K. Shirouzu
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago, IL, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591524
[Presentation] Cap43/NDRG-1抑制によるヒト乳癌細胞の骨転移の制御2006
- Author(s)
  平岡弘二, 善明美千久, 庄田孝則, 永田見生, 細井文仁, 馬崎雄二, 小野眞弓, 藤井輝彦, 桑野信彦
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591646

1. YAMANA Hideaki (30140669)

# of Collaborated Projects: 8 results

# of Collaborated Products: 1 results
2. ISHIBASHI Masatoshi (20168256)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. HAYABUCHI Naofumi (20108731)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KAIDA Hayato (40299425)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. FUJITA Hiromasa (90156878)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SUEYOSHI Susumu (30235840)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SEKI Naoko (40226634)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
8. TOH Uhi (60268901)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
9. KAGE Masayoshi (80148840)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
10. HIRAOKA Kohji (10268914)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. SHOUDA Takanori (10352163)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. KURATA Seiji (80268888)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. SHIMA Ichiro (60178928)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. YASUNAGA Masafumi (50268843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KITASATO Yuhei (20569363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. UCHIDA Masafumi (50168704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. DOI Ryosuke (40400048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. IRIE Hitoshi (40176516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KONAKA Toshio (00195752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TOMITA Yusuke (30197933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. JYO Seiya (30196662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SHINOZAKI Koji (70226140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TANAKA Toshiaki (20227151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TANAKA Ken (60217023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TODA Yukihiro (80217512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. FUJIMOTO Kiminori (00199366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. HAYASHI Akihiro (70180958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KATO Seiya (60268844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. ZEMMYO Michihisa (10289465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. HAMADA Tetsuya (20341349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. YOKOYAMA Goro (00309808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. YAMAGUCHI Miki (70330834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. KUWANO Michihiko (80037431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
34. 木下壽文 (50186293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 力武浩 (30191688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 白水玄山 (10154379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 藤勇二 (50197836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 小野崇典 (00185638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 西田秀美 (50180617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 寺崎洋 (30268891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 広松雄治 (10201740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 主藤朝也 (50309803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. WAKIOKA Tohru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJII Teruhiko 藤井 輝彦

藤井 輝彦 フジイ テルヒコ

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乳癌における分子標的治療薬に対する薬剤耐性機構の解明Principal Investigator

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Study of drug sensitivity to molecular targeting drugs in breast cancerPrincipal Investigator

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Role of protein kinase C and chimaerin in esophageal cancer cellsPrincipal Investigator

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FUJII Teruhiko 藤井輝彦

藤井輝彦フジイテルヒコ