Tamura Hiroomi 田村悦臣

… Alternative Names

TAMURA Hiroomi 田村悦臣

TAMURA Hiro-omi 田村悦臣

田村悦臣タムラヒロオミ

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Researcher Number	50201629
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 薬学部(芝共立), 名誉教授
Affiliation (based on the past Project Information) *help	2020: 慶應義塾大学, 薬学部(芝共立), 名誉教授 2016 – 2019: 慶應義塾大学, 薬学部(芝共立), 教授 2009 – 2015: Keio University, 薬学部, 教授 2001: Hygienic Chemistry, Kyoritsu College of Pharmacy Professor, 衛生化学講座, 教授 2000: 共立薬科大学, 薬学部・衛生化学教室, 助教授 1993 – 1994: 名古屋市立大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Eating habits, studies on eating habits / Basic Section 59040:Nutrition science and health science-related / Eating habits / Environmental pharmacy Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator コーヒー / 生活習慣病 / 肥満 / 認知症 / Nrf2 / 抗炎症 / P450 / 硫酸転移酵素 / 乳がん / 大腸がん … More / エストロゲン / プロテアソーム / NFκB / tamoxifen / カテコール / アミロイドβ / BACE1 / 炎症 / 白内障 / 焙煎 / IRS1 / 糖尿病 / 予防薬学 / environmental pollutant / oxidative stress / culture cells / glutathione S-transferase / UDP-glucuronyl transferase / blood / drug metabolism / P-450 / 環境汚染化学物質 / 酸化ストレス / 培養細胞 / グルタチオンS-転移酵素 / グルクロン酸転移酵素 / 血液 / 薬物代謝酵素 / SULT1E1 / ras遺伝子 / miRNA / 脂肪細胞 / 予防 / がん / 神経ステロイド / 前立腺がん / ステロイドホルモン / 消化管 / 硫酸抱合 … More Except Principal Investigator GPI-achored proteins / site-directed mutagenesis / primary structure-activity relationship / Primayr stucture of phospholipases / Bacillus thuringiensis phosphatidylinositol-specific phospholipase C / Penicillium notatum phospholipase B / Bacillus cereus sphingomyelinase / Microbial phospholipases / ホスホリパーゼ / 酸素蛋白質一次構造 / 酵素活性部位 / 酵素蛋白質一次構造 / Bacillus thuringiensis / Bacillus cereus / Penicillium notatum / PI特異的ホスホリパーゼC / スフィンゴミエリナーゼ / ホスホリパーゼB Less

Molecular analysis of preventive effects of coffee constituents on life-style-related diseases via protein degradations.Principal Investigator
- Principal Investigator
  
  Tamura Hiroomi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Keio University
Investigation of molecular basis of preventive effects of coffee consumption on lifestyle-related diseases.Principal Investigator
- Principal Investigator
  
  TAMURA Hiroomi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Keio University
Effects of coffee consumption on steroid metabolisms linked to life-style related disorders.Principal Investigator
- Principal Investigator
  
  TAMURA Hiroomi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Keio University
Study for the correlation between lifestyle-related diseases and the inhibition of estrogen sulfo-conjugation by coffee.Principal Investigator
- Principal Investigator
  
  TAMURA Hiroomi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Keio University
Expression pro filing of drug metabolizing enzymes in human myeloblastic and lymphoid cell linesPrincipal Investigator
- Principal Investigator
  
  TAMURA Hiro-omi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyoritsu College of Pharmacy
Analytical study of the primary structures of microbial phospholipases on the basis of molecular biology
- Principal Investigator
  
  IKEZAWA Hiroh
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] Chapter 61. Effects of Coffee on Estrogen Sulfation in Human Colon Carcinoma Caco-2 Cells. in "Coffee in health and Disease Prevention"2015
- Author(s)
  Hiroomi Tamura (ed. V. Preedy)
- Total Pages
  8
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-15K00883
[Book] Coffee in Health and Disease Prevention2015
- Author(s)
  H. Tamura
- Total Pages
  1046
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-24500996
[Journal Article] Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2.2020
- Author(s)
  Funakoshi-Tago M, Nonaka Y, Tago K, Takeda M, Ishihara Y, Sakai A, Matsutaka M, Kobata K, Tamura H.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 2584-2584
- DOI
  10.1038/s41598-020-59380-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11109, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-20K07035
[Journal Article] Molecular basis of preventive effects of habitual coffee intake against chronic diseases2020
- Author(s)
  Hiroomi Tamura
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 140 Pages: 1351-1363
- NAID
  130007933470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11109
[Journal Article] Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells.2020
- Author(s)
  Funakoshi-Tago M, Tago K, Li C, Hokimoto S, Tamura H.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(1) Issue: 1 Pages: 19588-19588
- DOI
  10.1038/s41598-020-76445-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07035, KAKENHI-PROJECT-18K11109
[Journal Article] Coffee brew intake can prevent the reduction of lens glutathione and ascorbic acid levels in HFD-fed animals.2019
- Author(s)
  Nakazawa Y, Ishimori N, Oguchi J, Nagai N, Kimura M, Funakoshi-Tago M, Tamura H.
- Journal Title
  
  Exp Ther Med.
  
  Volume: 17(2) Pages: 1420-1425
- DOI
  10.3892/etm.2018.7092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08286, KAKENHI-PROJECT-18K11109
[Journal Article] Roasted Coffee Reduces β-Amyloid Production by Increasing Proteasomal β-Secretase Degradation in Human Neuroblastoma SH-SY5Y Cells.2018
- Author(s)
  Fukuyama K, Kakio S, Nakazawa Y, Kobata K, Funakoshi-Tago M, Suzuki T, Tamura H.
- Journal Title
  
  Mol Nutr Food Res.
  
  Volume: 62(21) Issue: 21 Pages: 1800238-1800238
- DOI
  10.1002/mnfr.201800238
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08286, KAKENHI-PROJECT-18K11109, KAKENHI-PUBLICLY-18H04851, KAKENHI-PROJECT-18H02566
[Journal Article] Enhances the Anti-Cataract Effect of Coffee Beans: Ameliorating Selenite-Induced Cataracts in Rats.2017
- Author(s)
  Ishimori N, Oguchi J, Nakazawa Y, Kobata K, Funakoshi-Tago M, Tamura H
- Journal Title
  
  Current Eye Research
  
  Volume: - Issue: 6 Pages: 864-870
- DOI
  10.1080/02713683.2016.1262877
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K00883, KAKENHI-PROJECT-16K18957, KAKENHI-PROJECT-17K08286
[Journal Article] Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS12017
- Author(s)
  Maki C, Funakoshi-Tago M, Aoyagi R, Ueda F, Kimura M, Kobata K, Tago K, Tamura H
- Journal Title
  
  PLoS One
  
  Volume: 12(3) Issue: 3 Pages: e0173264-e0173264
- DOI
  10.1371/journal.pone.0173264
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17K08286, KAKENHI-PROJECT-15K00883
[Journal Article] Administration of antioxidant compounds affects the lens chaperone activity and prevents the onset of cataracts.2017
- Author(s)
  Nakazawa Y, Nagai N, Ishimori N, Oguchi J, Tamura H.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 95 Pages: 137-143
- DOI
  10.1016/j.biopha.2017.08.055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K00883, KAKENHI-PROJECT-16K18957
[Journal Article] Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNAs.2017
- Author(s)
  Nakayama T, Funakoshi-Tago M, Tamura H.
- Journal Title
  
  Oncol Lett.
  
  Volume: 14 Issue: 1 Pages: 1109-1114
- DOI
  10.3892/ol.2017.6227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08286, KAKENHI-PROJECT-15K00883
[Journal Article] Roasted coffee induces aldo-keto reductase 1C3 (AKR1C3) expression in human prostate cancer LNCaP cells associated with Nrf2 activation.2016
- Author(s)
  Kuniji Takahashi, Megumi Funakoshi-Tago, Marie Takaoka, Shota Kakio, Kenji Kobata, and Hiroomi Tamura
- Journal Title
  
  Oncology Letters
  
  Volume: -
- DOI
  10.3892/ol.2016.5334
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K00883
[Journal Article] Coffee induces vascular endothelial growth factor (VEGF) expression in human neuroblastama SH-SY5Y cells.2016
- Author(s)
  Shota Kakio, Megumi Funakoshi-Tago, Kenji Kobata and Hiroomi Tamura
- Journal Title
  
  Nutritional Neuroscience
  
  Volume: - Issue: 6 Pages: 336-342
- DOI
  10.1080/1028415x.2015.1133106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K00883
[Journal Article] A proline type fullerene derivative inhibits adipogenesis by preventing PPARgamma activation.2016
- Author(s)
  Megumi Funakoshi-Tago, Takahiro Hattori, Fumihito Ueda, Kenji Tago, Tomoyuki Ohe, Tadahiko Mashino and Hiroomi Tamura
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 5 Pages: 259-265
- DOI
  10.1016/j.bbrep.2016.01.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K00883, KAKENHI-PROJECT-26440062
[Journal Article] Nepetaefuran and leonotinin isolated from Leonotis nepetaefolia R. Br. potently inhibit the LPS signaling pathway by suppressing the transactivation of NF-κB.2015
- Author(s)
  eda F, Iizuka K, Tago K, Narukawa Y, Kiuchi F, Kasahara T, Tamura H, Funakoshi-Tago M.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 28 Issue: 2 Pages: 967-976
- DOI
  10.1016/j.intimp.2015.08.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K00883, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-25460073
[Journal Article] Coffee modulates the function of brain-derived neurotrophic factor (BDNF) in human neuroblastoma SH-SY5Y cells.2015
- Author(s)
  Shota Kakio, Yosuke Nakazawa, Megumi Funakoshi-Tago and Hiroomi Tamura
- Journal Title
  
  Neuroscience & Medicine
  
  Volume: 6 Issue: 04 Pages: 165-174
- DOI
  10.4236/nm.2015.64025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K00883
[Journal Article] Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway.2015
- Author(s)
  Funakoshi-Tago M, Okamoto K, Izumi R, Tago K, Yanagisawa K, Narukawa Y, Kiuchi F, Kasahara T, Tamura H.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 25 Pages: 189-198
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K00883
[Journal Article] Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway.2015
- Author(s)
  Funakoshi-Tago M, Okamoto K, Izumi R, Tago K, Yanagisawa K, Narukawa Y, Kiuchi F, Kasahara T, Tamura H.
- Journal Title
  
  Int. Immunopharmacol.
  
  Volume: 25 Issue: 1 Pages: 189-198
- DOI
  10.1016/j.intimp.2015.01.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500996, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-25460073, KAKENHI-PROJECT-26440062
[Journal Article] Coffee Inhibits Adipocyte Differentiation <i>via</i> Inactivation of PPARγ2014
- Author(s)
  Ryohei Aoyagi, Megumi Funakoshi-Tago, Yosuke Fujiwara, Hiroomi Tamura
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 11 Pages: 1820-1825
- DOI
  10.1248/bpb.b14-00378
- NAID
  130004687250
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500996
[Journal Article] Dexamethasone suppresses neurosteroid biosynthesis via downregulation of steroidogenic enzyme gene expression in human glioma GI-1 cells.2014
- Author(s)
  Fuyuko Koibuchi, Natsumi Ritoh, Megumi Funakoshi-Tago, Hiroomi Tamura
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 37
- NAID
  130004057421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500996
[Journal Article] Human keratinocyte caspase-14 expression is altered in human epidermal 3D models by dexamethasone and by natural products used in cosmetics2013
- Author(s)
  Kataoka S, Hattori K, Date A, Tamura H
- Journal Title
  
  Arch. Dermatol. Res.
  
  Volume: 305 Issue: 8 Pages: 683-689
- DOI
  10.1007/s00403-013-1359-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500996
[Journal Article] New diterpenoids with estrogen sulfotransferase inhibitory activity from Leonurus sibiricus L.2013
- Author(s)
  Yuji Narukawa, Akiko Niimura, Hitomi Noguchi, Hiroomi Tamura, Fumiyuki Kiuchi
- Journal Title
  
  J. Nat. Med.
  
  Volume: 68 Issue: 1 Pages: 125-131
- DOI
  10.1007/s11418-013-0781-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500996
[Journal Article] Coffee reduces SULT1E1 expression in human colon carcinoma Caco-2 cells.2013
- Author(s)
  Marina Isshiki, Haruka Ohta, Hiroomi Tamura
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 36 Pages: 229-3004
- NAID
  130003361375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500996
[Journal Article] Interferon gamma induces steroid sulfatase expression in human keratinocytes.2012
- Author(s)
  Hattori K, Yamaguchi N, Umezawa K, Tamura H
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 35 Pages: 1588-1593
- NAID
  130001872068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500996
[Journal Article] Interferon gamma induces steroid sulfatase expression in human keratinocytes2012
- Author(s)
  Hattori K, Yamaguchi N, Umezawa K, Tamura H.
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 35(9)(in press)
- NAID
  130001872068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500792
[Journal Article] Coffee induces Breast Cancer Resistance Protein Expression in Caco-2 cells2011
- Author(s)
  Isshiki, Umezawa, Tamura
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 34 Pages: 1624-1627
- NAID
  130001086598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500792
[Journal Article] Coffee induces breast cancer resistance protein expression in Caco-2 cells2011
- Author(s)
  Isshiki M, Umezawa K, Tamura H.
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 34(10) Pages: 1624-1627
- NAID
  130001086598
- URL
  http://dx.doi.org/10.1248/bpb.34.1624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500792
[Journal Article] Sulfation of estradiol in human epidermal keratinocyte2011
- Author(s)
  Kushida A. Hattori K. Yamaguchi N. Kobayashi T. Tamura H.
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 34(7) Pages: 1147-1151
- NAID
  130000738113
- URL
  http://dx.doi.org/10.1248/bpb.34.1147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500792
[Journal Article] Coffee induces 11β-hydroxysteroid dehydrogenase type 2 activity in human placental choriocarcinoma cells2011
- Author(s)
  Arao T, Tamura H.
- Journal Title
  
  J. Health Sci.
  
  Volume: 57(5) Pages: 436-441
- URL
  http://dx.doi.org/10.1248/jhs.57.436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500792
[Journal Article] Effects of coffee on the metabolism of glucocorticoid in human syncytiot rophoblast JEG-3 cells.2010
- Author(s)
  Arao, T., Tamura, H.
- Journal Title
  
  Journal of Health Science
  
  Volume: 56, supplement Pages: 131-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500792
[Journal Article] ヒト消化管を用いたin vitro試験の有用性と課題について考える2009
- Author(s)
  田村悦臣
- Journal Title
  
  HAB NEWS LETTER
  
  Volume: 16巻No.1 Pages: 7-8
- URL
  http://www.hab.or.jp/
- Data Source
  KAKENHI-PROJECT-21500792
[Journal Article] ヒト消化管組織を用いたin vitro試験の有用性と課題について考える2009
- Author(s)
  田村悦臣
- Journal Title
  
  HAB News Letter 16
  
  Pages: 7-8
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] コーヒーを飲んで延ばす健康寿命　～コーヒーの薬‘離’学～2020
- Author(s)
  田村悦臣
- Organizer
  日本コーヒー文化学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] 今いちど，眼科領域の進歩を考える―基礎，臨床，そしてドラッグリポジショニングについて―2020
- Author(s)
  中澤洋介、多胡めぐみ、田村悦臣
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] 正常マウス海馬におけるAβ発現及び記憶能に対するコーヒー焙煎成分の効果2020
- Author(s)
  保木本真梧、渋澤春風、中澤洋介、多胡めぐみ、田村悦臣
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] コーヒーの抗白内障効果の分子メカニズムの解析2019
- Author(s)
  小林亮太、音羽遼太郎、青木美紀、中澤洋介、多胡めぐみ、田村悦臣
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] 抗炎症作用を示すコーヒー含有成分の同定2019
- Author(s)
  豊嶋直樹、松高茉里、古旗賢二、多胡憲治、多胡めぐみ、田村悦臣
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] Molecular basis of preventive effects of coffee on neurodegenerative diseases.2019
- Author(s)
  H. Tamura
- Organizer
  2nd International conference on neuromuscular and neurodegenerative diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] 抗炎症を示すコーヒー含有成分の同定2018
- Author(s)
  松髙　茉里、多胡めぐみ、多胡憲治、古旗賢二、田村悦臣
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] コーヒーの水晶体上皮細胞株に対する抗アポトーシス効果の検討2018
- Author(s)
  鈴木正太、中澤洋介、平松範子、長井紀章、多胡めぐみ、山本直樹、田村悦臣
- Organizer
  第57回日本白内障学会総会
- Data Source
  KAKENHI-PROJECT-18K11109
[Presentation] コーヒーによる肥満誘導白内障予防効果の検討2018
- Author(s)
  鈴木正太、中澤洋介、福山和也、石森奈奈、小口潤、多胡めぐみ、田村悦臣
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] MCF-7 細胞におけるエストロゲン受容体の発現に対するコーヒーの影響2017
- Author(s)
  李チン、多胡めぐみ、中澤洋介、田村悦臣
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] Coffee reduces BACE1 expression by activation of proteasomal degradation in human neuroblastoma SH-SY5Y cells.2017
- Author(s)
  K. Fukuyama, S. Kakio, K. Kobata, T. Suzuki, M. Tago, H. Tamura
- Organizer
  第60回日本神経化学会（仙台）大会
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] コーヒーは神経芽細胞腫においてプロテアソームを活性化することによってBACE1のタンパク発現を抑制する2017
- Author(s)
  福山和也、垣尾将太、古旗賢二、鈴木利治、多胡めぐみ、田村悦臣
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] 抗炎症作用を示すコーヒー含有成分の同定及びその作用機序の解析2017
- Author(s)
  松髙茉里、並木淳裕、古旗賢二、多胡めぐみ、田村悦臣
- Organizer
  平成29年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] コーヒーによる白内障抑制効果の検討2016
- Author(s)
  石森奈奈、中澤洋介、多胡めぐみ、岡美佳子、竹鼻眞、田村悦臣
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] コーヒーによる白内障抑制効果の検討2016
- Author(s)
  田村悦臣、中澤洋介、石森奈奈、小口潤、多胡めぐみ
- Organizer
  第42回水晶体研究会
- Place of Presentation
  いわて県民情報交流センター　アイ―ナ（岩手県盛岡市）
- Year and Date
  2016-07-31
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] コーヒー豆抽出液が示す抗炎症作用の検討2016
- Author(s)
  谷尾真由美、野中勇佑、多胡めぐみ、田村悦臣
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] 白内障効果をもつコーヒー成分の解析.2016
- Author(s)
  小口潤, 石森奈奈, 中澤洋介, 多胡めぐみ, 田村悦臣
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-09-21
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNA.2016
- Author(s)
  Tamura H. Nakayama T, Funakoshi-Tago M.
- Organizer
  ESPEN 2016
- Place of Presentation
  Copenhagen(Denmark)
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] コーヒー成分によるヒト神経芽細胞腫におけるβ-セクレターゼ発現の抑制効果.2016
- Author(s)
  福山和也, 垣尾将大, 古旗賢二, 鈴木利治, 多胡めぐみ, 田村悦臣
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] 抗炎症作用を示すコーヒー含有成分の解析2016
- Author(s)
  松髙茉里, 上田史仁, 古旗賢二, 中澤洋介, 多胡めぐみ, 田村悦臣
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-09-21
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] ヒト乳がん由来MCF-7細胞におけるエストロゲン代謝に対するコーヒー豆抽出液の影響2015
- Author(s)
  武田　峰佳,露崎英子,多胡めぐみ,田村悦臣
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] コーヒー豆抽出液によるLPSシグナル伝達経路抑制機構の解析2015
- Author(s)
  野中勇佑、石原由麻、多胡めぐみ、古旗賢二、田村悦臣
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] コーヒーによる認知症予防効果の分子基盤の解析2015
- Author(s)
  田村悦臣
- Organizer
  第５回日本認知症予防学会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] ヒト神経芽細胞腫SH-SY5Yにおける血管内皮増殖因子VEGF発現に対するコーヒーの影響2015
- Author(s)
  垣尾翔大、古旗賢二、多胡めぐみ、田村悦臣
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] ヒト神経芽細胞腫SH-SY5YにおけるBACE1発現に対するコーヒーの効果2015
- Author(s)
  福山和也、垣尾翔大、古旗賢二、鈴木利治、多胡めぐみ、田村悦臣
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] SH-SY5Y細胞における血管内皮増殖因子VEGFの発現に対するコーヒーの影響2015
- Author(s)
  垣尾翔大、榎崇一郎、古旗賢二、多胡めぐみ、田村悦臣
- Organizer
  第５回日本認知症予防学会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] ヒト結腸がん由来Caco-2細胞のK-ras発現に対するコーヒーの影響2015
- Author(s)
  中山拓哉、辻山　真,　多胡めぐみ,　田村悦臣
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] Coffee reduces BACE1 expression in human neuroblastoma SH-SY5Y cells.2015
- Author(s)
  Kazuya Fukuyama, Shota Kakio, Soichiro Enoki, Kenji Kobata, Toshiharu Suzauki, Megumi Funakoshi-Tago, Hiroomi Tamura.
- Organizer
  第58回日本神経化学会（大宮）大会
- Place of Presentation
  大宮ソニックシティー（埼玉県大宮市）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] ヒト結腸がん細胞のK-ras発現に対するコーヒーの効果2015
- Author(s)
  中山拓哉、八木利恭、多胡（船越）めぐみ、田村悦臣
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] Coffee induces vascular endothelial growth factor expression in human neuroblastoma SH-SY5Y cells2015
- Author(s)
  Shota Kakio, Soichiro Enoki, Kenji Kobata, Megumi Funakoshi-Tago, Hiroomi Tamura
- Organizer
  25th Meeting of the International Society for Neurochemistry
- Place of Presentation
  Cains (Australia)
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] Effects of coffee on vascular endothelial growth factor expression in human neuroblastoma SH-SY5Y cells2015
- Author(s)
  Shota Kakio, Soichiro Enoki, Kenji Kobata, Megumi Funakoshi-Tago, Hiroomi Tamura.
- Organizer
  第58回日本神経化学会（大宮）大会
- Place of Presentation
  大宮ソニックシティー（埼玉県大宮市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K00883
[Presentation] SH-SY5Y細胞において、コーヒーが脳由来神経栄養因子ＢＤＮＦの働きに及ぼす影響2014
- Author(s)
  垣尾翔大, 高橋克徳, 多胡めぐみ, 田村悦臣
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] マウス脂肪前駆細胞3T3-L1の分化初期段階における一過性細胞増殖へのコーヒーの影響2014
- Author(s)
  牧千洋, 青柳良平, 多胡めぐみ, 田村悦臣
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] SH-SY5Y細胞における脳由来神経栄養因子BDNFの働きに対するコーヒーの影響2014
- Author(s)
  垣尾翔大、多胡めぐみ、田村悦臣
- Organizer
  第５７回日本神経化学会大会
- Place of Presentation
  奈良
- Year and Date
  2014-09-30
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] 脂肪細胞分化におけるRNA helicase DDX5の役割2014
- Author(s)
  野間瞭太, 多胡めぐみ, 多胡憲治, 柳沢健, 田村悦臣
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] Caco-2細胞におけるBCRP発現に対するコーヒーの効果2012
- Author(s)
  太田遥香, 一色真里奈, 木島文, 梅沢一夫, 田村悦臣
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] JEG-3細胞におけるグルココルチコイド代謝反応に対するコーヒーの効果2012
- Author(s)
  鯉渕芙由子, 矢作祐人, 荒尾智美, 田村悦臣
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] ヒト表皮三次元培養モデルにおけるコーヒーの表皮分化マーカー発現誘導効果2012
- Author(s)
  青柳良平, 服部研之, 伊達朗, 田村悦臣
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] コーヒーによるステロイド代謝調節を介した予防薬学の可能性2011
- Author(s)
  田村悦臣
- Organizer
  第4回食品薬学シンポジウム
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] コーヒーによるステロイド代謝調節を介した予防薬学の可能性2011
- Author(s)
  田村悦臣
- Organizer
  第4回食品薬学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] コーヒーによるヒト消化管モデルCaco-2細胞におけるBCRP発現誘導2011
- Author(s)
  一色真里奈, 田村悦臣
- Organizer
  日本薬学会第131年会
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] Coffee induces 11β-hydroxysteroid dehydrogenase type 2 activity in cultured human placental trophoblast JEG-32011
- Author(s)
  Hiroomi Tamura
- Organizer
  7th Asia Pacific Coference on Clinical Nutrition
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] コーヒーによるヒト消化管モデルCaco-2細胞におけるBCRP発現誘導2011
- Author(s)
  一色真里菜、田村悦臣
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] ヒト消化管モデルCaco-2細胞のエストロゲン代謝に対するコーヒーの影響2010
- Author(s)
  一色真里奈、田村悦臣
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] ヒト消化管モデルCaco-2細胞のエストロゲン代謝に対するコーヒーの影響2010
- Author(s)
  一色真里奈, 田村悦臣
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] ヒト胎盤絨毛細胞由来JEG-3におけるグルココルチコイド代謝に対するコーヒーの影響2010
- Author(s)
  荒尾智美、田村悦臣
- Organizer
  フォーラム2010 衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] 消化管モデルCaco-2細胞のエストロゲン硫酸抱合に対するコーヒーの影響2010
- Author(s)
  一色真里奈, 田村悦臣
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-21500792
[Presentation] メタ解析を用いた日本の大腸がん発症に対するコーヒー摂取の有用性評価.
- Author(s)
  清水美貴子, 吉田美咲, 橋口正行, 望月眞弓, 田村悦臣
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] コーヒーによるエストロゲン硫酸転移酵素SULT1E1の発現抑制の解析
- Author(s)
  太田遙香, 一色真里菜, 田村悦臣
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] マウス脂肪前駆細胞3T3L1におけるinsulinシグナルへのコーヒーの影響.
- Author(s)
  牧千洋, 青柳良平, 多胡めぐみ, 田村悦臣
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] ヒト由来前立腺がんLNPCap細胞のアンドロゲン代謝に対するコーヒーの影響
- Author(s)
  高橋國次、田村悦臣
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] コーヒーによる脂肪細胞分化抑制効果とそのメカニズム解析.
- Author(s)
  青柳良平, 牧千洋, 田村悦臣
- Organizer
  フォーラム2013 衛生薬学・環境トキシコロジー
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] Evaluation of goldensilk-derived extract epidermal barrier marker, caspase-14 and related genes in human skin equivalent models.
- Author(s)
  Hattori K, Date A, Toyama K, Tamura H
- Organizer
  International Investigative Dermatology Meeting
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] SH-SY5Y細胞における脳由来神経栄養因子BDNFの働きに対するコーヒーの効果.
- Author(s)
  垣尾翔太, 高橋克徳, 多胡めぐみ, 田村悦臣
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] 脂肪前駆細胞3T3-L1を用いたコーヒーの脂肪細胞分化への影響
- Author(s)
  青柳良平、田村悦臣
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] Effects of coffee on BDNF activity in human neuroblastoma SH-SY5Y cells.
- Author(s)
  S. Kakio, K. Takahashi, M. Tago-Funakoshi, H. Tamura
- Organizer
  The 12th International Congress on Alzheimer's and Parkinson's diseases.
- Place of Presentation
  Nice, France
- Year and Date
  2015-03-18 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] ヒト肝HepG2細胞の抱合反応に対するコーヒーの影響
- Author(s)
  垣尾翔太、眞鍋陽子、田村悦臣
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] コーヒーによる脂肪細胞への分化抑制メカニズムの解析.
- Author(s)
  青柳良平, 牧千洋, 多胡めぐみ, 田村悦臣
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] ヒト神経膠種GI-1細胞における神経ステロイド生合成に対するグルココルチコイドの影響.
- Author(s)
  鯉渕芙由子, 利藤奈都美, 田村悦臣
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] ヒト由来前立腺がんLNCap細胞に対するアンドロゲン作用へのコーヒーの影響.
- Author(s)
  高橋國次, 田村悦臣
- Organizer
  フォーラム2013 衛生薬学・環境トキシコロジー
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24500996
[Presentation] 脂肪前駆細胞3T3-L1を用いたコーヒーの脂肪細胞分化への影響.
- Author(s)
  青柳良平, 牧千洋, 田村悦臣
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24500996

1. 多胡めぐみ (30445192)

# of Collaborated Projects: 2 results

# of Collaborated Products: 37 results
2. IKEZAWA Hiroh (40080163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KOBAYASHI Tomoko (70214533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TSUKAMOTO Kikuo (20183478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAGUCHI Ryo (20080210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAGO Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tamura Hiroomi 田村 悦臣

TAMURA Hiroomi 田村 悦臣

TAMURA Hiro-omi 田村 悦臣

田村 悦臣 タムラ ヒロオミ

Research Projects

Research Products

Co-Researchers

Molecular analysis of preventive effects of coffee constituents on life-style-related diseases via protein degradations.Principal Investigator

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Investigation of molecular basis of preventive effects of coffee consumption on lifestyle-related diseases.Principal Investigator

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Effects of coffee consumption on steroid metabolisms linked to life-style related disorders.Principal Investigator

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Study for the correlation between lifestyle-related diseases and the inhibition of estrogen sulfo-conjugation by coffee.Principal Investigator

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Expression pro filing of drug metabolizing enzymes in human myeloblastic and lymphoid cell linesPrincipal Investigator

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Analytical study of the primary structures of microbial phospholipases on the basis of molecular biology

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[Book] Chapter 61. Effects of Coffee on Estrogen Sulfation in Human Colon Carcinoma Caco-2 Cells. in "Coffee in health and Disease Prevention"2015

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[Book] Coffee in Health and Disease Prevention2015

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[Journal Article] Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2.2020

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[Journal Article] Molecular basis of preventive effects of habitual coffee intake against chronic diseases2020

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NAID

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[Journal Article] Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells.2020

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[Journal Article] Coffee brew intake can prevent the reduction of lens glutathione and ascorbic acid levels in HFD-fed animals.2019

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[Journal Article] Roasted Coffee Reduces β-Amyloid Production by Increasing Proteasomal β-Secretase Degradation in Human Neuroblastoma SH-SY5Y Cells.2018

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[Journal Article] Enhances the Anti-Cataract Effect of Coffee Beans: Ameliorating Selenite-Induced Cataracts in Rats.2017

Author(s)

Tamura Hiroomi 田村悦臣

TAMURA Hiroomi 田村悦臣

TAMURA Hiro-omi 田村悦臣

田村悦臣タムラヒロオミ