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Asahina Akihiko  朝比奈 昭彦

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ASAHINA Akihiko  朝比奈 昭彦

朝比奈 昭彦  アサヒナ アキヒコ

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Researcher Number 50202601
Other IDs
Affiliation (Current) 2025: 東京慈恵会医科大学, 医学部, 教授
2025: 独立行政法人国立病院機構(相模原病院臨床研究センター), アトピー性皮膚炎研究室, 研究員
Affiliation (based on the past Project Information) *help 2008: 東京大学, 医学部・附属病院, 助教授
2007: Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital, Clinical Research Center, National Hospital Organization Sagamihara Hospital, Researcher
2005 – 2006: 独立行政法人国立病院機構(相模原病院臨床研究センター), アレルギー性疾患研究部, 研究員
2004 – 2005: The University of Tokyo, Faculty of Medicine, Assistant Professor, 医学部附属病院, 助教授
2001: Faculty of Medicine, Lecturer, 医学部附属病院, 講師 … More
1999 – 2001: 東京大学, 医学部・附属病院, 講師
1998: 東京大学, 医学部・付属病院分院, 講師
1997: 東京大学, 医学部・付属病院, 助手
1996 – 1997: 東京大学, 医学部・附属病院, 助手
1995: 東京大学, 医学部(病), 助手
1992: 東京大学, 医学部(病), 助手
1991: 東京大学, 医学部・(病)皮膚科, 助手
1990: 東京大学, 医学部・附属病院・分院・皮膚科, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Dermatology
Except Principal Investigator
Dermatology / Dermatology
Keywords
Principal Investigator
樹状細胞 / ランゲルハンス細胞 / 血管内皮細胞 / vitamin D / psoriasis / type I interferons / Langerhans cells / dendritic cells / Immunology / ビタミンD3 … More / ビタミンD / 乾癬 / I型インターフェロン / 免疫学 / GM-CSF / 枝状細胞 / ヘルパーT細胞 / TGFβ / IL-12 / セレクチン / グリセオフルビン / コルヒチン / VCAM-1 / 接着分子 / 微小管 / 接触過敏反応 / ロイコトリエンB_4 … More
Except Principal Investigator
ランゲルハンス細胞 / サイトカイン / 樹状細胞 / MEC / CTACK / TARC / TGF-β / Th_1 / IL-12 / CD23 / Langerhans cells / マウス / ケラチノサイト / transgenic mice / Chemokine / Keratino cytes / Dendritic cells / Lagerhans cells / 皮膚疾患 / Toll-like recepter / Eotaxin-3 / トランスジェニックマウス / ケモカイン / Prion / esiticesfeird / cytokine production / CD40L / 免疫抑制薬 / B7-2 / B7-1 / CD40 / TNF-α / M-CSF / GM-CSF / プリオン / ステロイド / サイトカイン産生 / atopic dermatitis / mycosis fungoides / T cells / cytokine / IL-7 transgenic / extrathymic T cell development / fetal skin / 皮膚 / 接着分子 / RAG-1,2 / マウス胎仔皮膚 / アトピー性皮膚炎 / 皮膚T細胞リンパ腱 / T細胞 / ラレゲルハンス細胞 / ル-クトランスジェニックマウス / 胸腺外分化 / 胎仔付着 / 活性化 / 抗原提示 / 共刺激分子 / PCRCpolymerase chain reaction / 尋常性乾癬 / ^<73>Ala(73番目のアラニン) / HLAーCx53 / HLAーCw11 / HLAーCw6,Cw7 / アスパラギン酸9番目 / アラニン73番目 / HLAーC / レオウイルス / 9番目アスパラギン酸 / 73番目アラニン / HLA-C分子 / 乾癬 Less
  • Research Projects

    (9 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (10 People)
  •  Investigation of Langerhans cell stimulatory molecule and its application in skin disease therapy

    • Principal Investigator
      TAMAKI Kunihiko
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  Regulation of Langerhans cell function by type I interferons with elucidation of its significancePrincipal Investigator

    • Principal Investigator
      ASAHINA Akihiko
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
      The University of Tokyo
  •  The rote of chemokine and dendritic cells in skin diseases

    • Principal Investigator
      TAMAKI Kunihiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  ランゲルハンス細胞のIL-12産生制御機構とその意義の解明Principal Investigator

    • Principal Investigator
      朝比奈 昭彦
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  Establishment of Langerhans cell-cell line and its spplication for treatment

    • Principal Investigator
      TAMAKI Kunihiko
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  微小管阻害剤による免疫修飾メカニズムの解明Principal Investigator

    • Principal Investigator
      朝比奈 昭彦
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  マウスを用いた接触過敏反応のロイコトリエンB_4アンタゴニストによる修飾Principal Investigator

    • Principal Investigator
      朝比奈 昭彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  Ontogeny of T cells in skin : extrathymic development

    • Principal Investigator
      TAMAKI Kunihiko
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo
  •  乾癬患者の遺伝的マーカーおよび疾患感受性遺伝子の分子レベルでの解析

    • Principal Investigator
      中川 秀己
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokyo

All 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Langerhans cells: unique character in dendritic cells2008

    • Author(s)
      Asahina A, Fujita H, Tada Y
    • Journal Title

      Expert Review of Dermatology 3(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Langerhans cells unique character in dendritic cells.2008

    • Author(s)
      Asahina A, Fujita H, Tada Y.
    • Journal Title

      Expert Review of Dermatology 3

      Pages: 293-306

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Langerhans cells: unique character in dendritic cells2008

    • Author(s)
      Asahina A, Fujita H, Tada Y
    • Journal Title

      Expert Review of Dermatology 3

      Pages: 293-306

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Early inflammatory changes in the "perilesional skin" of psoriatic plaques: is there interaction between dendritic cells and keratinocytes?2007

    • Author(s)
      Komine M, Karakawa M, Takekoshi T, Sakurai N, Minatani Y, Mitsui H, Tada Y, Saeki H, Asahina A, Tamaki K.
    • Journal Title

      Journal of Investigative Dermatology 127

      Pages: 1915-1922

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Early inflammatory changes in the "perilesional skin" of psoriatic plaques is there interaction between dendritic cells and keratinocytes?2007

    • Author(s)
      Komine M, Karakawa M, Takekoshi T, Sakurai N, Minatani Y, Mitsui H, Tada Y, Saeki H, Asahina A, Tamaki K.
    • Journal Title

      Journal of Investigative Dermatology 127

      Pages: 1915-1922

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Early inflammatory changes in the "perilesional skin" of psoriatic plaques : is there interaction between dendritic cells and keratinocytes2007

    • Author(s)
      Komine M, Karakawa M, Takekoshi T, Sakurai N, Minatani Y, Mitsui H, Tada Y, Saeki H, Asahina A, Tamaki K.
    • Journal Title

      J Invest Dermatol 127巻

      Pages: 1915-1922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells2007

    • Author(s)
      Fujita H, Asahina A, Komine M, Tamaki K.
    • Journal Title

      Cell Immunol 245巻

      Pages: 70-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells2007

    • Author(s)
      Fujita H, Asahina A, Komine M, Tamaki K
    • Journal Title

      Cellular Immunology 245

      Pages: 70-79

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] The direct action of 1alpha, 25(OH) 2-vitamin D3 on purified mouse Langerhans cells.2007

    • Author(s)
      Fujita H, Asahina A, Komine M, Tamaki K.
    • Journal Title

      Cellular Immunology 245

      Pages: 70-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Role of Langerhans cells in cutaneous protective immunity : is the reappraisal necessary?2006

    • Author(s)
      Asahina A, Tamaki K
    • Journal Title

      Journal of Dermatological Science 44

      Pages: 1-9

    • NAID

      10020548390

    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Ligation of E-cadheirs malecules on muie rasident Layuks cells inlinbids their maturation and chenhis prodution2006

    • Author(s)
      Fujita H, Asahina A, Tamaki K
    • Journal Title

      J Dermatol Sci 43(2)

      Pages: 152-5

    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] Role of Langerhans cells in cutaneous protective immunity : is the reappraisal necessary?2006

    • Author(s)
      Asahina A, Tamaki K.
    • Journal Title

      Journal of Dermatological Science 44

      Pages: 1-9

    • NAID

      10020548390

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Rde of Langerhaus cells in cutanecus protectss ismunety : is the appraisal necessary?2006

    • Author(s)
      Asahina A, Tamaki K
    • Journal Title

      J Dermotol Sci 44(1)

      Pages: 1-9

    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] Role of Langerhans cells in cutaneous protective immunity: is the reappraisal necessary?2006

    • Author(s)
      Asahina A, Tamaki K.
    • Journal Title

      Journal of Dermatological Science 44

      Pages: 1-9

    • NAID

      10020548390

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Type I interferons inhibit maturation and activation of mouse Langeirhans cells.2005

    • Author(s)
      Fujita H, Asahina A, Tada Y, Fujiwara H, Tamaki K.
    • Journal Title

      Journal of Investigative Dermatology 125

      Pages: 126-133

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Interleukin-4 and interleukin-13 enhance CCL26 production in a human keratinocyte cell line, HaCaT cells.2005

    • Author(s)
      Kagami S, Saeki H, Komine M, (omission), Asahina A, Tamaki K
    • Journal Title

      Clin Exp Immunol 141(3)

      Pages: 459-466

    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] Type I interferons inhibit maturation and activation of mouse Langerhans cells.2005

    • Author(s)
      Fujita H, Asahina A, Tada Y, Fujiwara H, Tamaki K
    • Journal Title

      Journal of Investigative Dermatology 125

      Pages: 126-133

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Type I interferons inhibit maturation and activation of mouse Langerhans cells.2005

    • Author(s)
      Fujita H, Asahina A, Tada Y, Fujiwara H, Tamaki K.
    • Journal Title

      Journal of Investigative Dermatology 125・1

      Pages: 126-133

    • Data Source
      KAKENHI-PROJECT-16591088
  • [Journal Article] Type I interferons inhibit maturation and activation of mouse Langerhans cells.2005

    • Author(s)
      Fujita H, Asahina A, Tada Y, Fujiwara H, Tamaki K
    • Journal Title

      J Invest Dermatol 125(1)

      Pages: 126-133

    • Data Source
      KAKENHI-PROJECT-17209039
  • [Journal Article] Differential production of Th1- and Th2-type chemokines by mouse Langerhans cells and splenic dendritic cells.2005

    • Author(s)
      Fujita H, Asahina A, (omission), Tamaki K
    • Journal Title

      J Invest Dermatol 124(2)

      Pages: 343-350

    • Data Source
      KAKENHI-PROJECT-17209039
  • [Presentation] Langerhans cells: unique character in dendritic cells2007

    • Author(s)
      Asahina A
    • Organizer
      21st World congress of Dermatology
    • Place of Presentation
      Buenos Aires,Argentina
    • Year and Date
      2007-10-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Presentation] Langerhans cells: unique character in dendritic cells2007

    • Author(s)
      Asahina A
    • Organizer
      21st World congress of Dermatology
    • Place of Presentation
      Buenos Aires, Argentina
    • Year and Date
      2007-10-01
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Presentation] Langerhans cells : unique character in dendritic cells.2007

    • Author(s)
      Akihiko Asahina.
    • Organizer
      The 21st World congress of Dermatology
    • Place of Presentation
      Buenos Aires, Argentina
    • Year and Date
      2007-10-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Presentation] 乾癬局面周辺部皮膚における樹状細胞の分布と形質2006

    • Author(s)
      小宮根真弓、竹腰知紀、桜井直樹、南谷洋策、佐伯秀久、朝比奈昭彦、玉置邦彦
    • Organizer
      日本研究皮膚科学会第31回年次学術大会・総会
    • Place of Presentation
      京都
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Presentation] 活性型ビタミンD3がマウスランゲルハンス細胞の機能に及ぼす影響の解析2006

    • Author(s)
      藤田英樹、朝比奈昭彦、小宮根真弓、玉置邦彦
    • Organizer
      日本皮膚科学会第810回東京地方会
    • Place of Presentation
      東京
    • Year and Date
      2006-12-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Presentation] Analysis of the functional effect of active form vitamin D3 on mouse Langerhans cells.2006

    • Author(s)
      Fujita H, Asahina A, Komine M, Tamaki K.
    • Organizer
      The 810th Tokyo regional meeting of the Japanese dermatological association
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-12-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • [Presentation] Distribution and phenotype of dendritic cells in the perilesional skin of psoriatic plaques.2006

    • Author(s)
      Komine M, Takekoshi T, Sakurai N, Minatani Y, Saeki H, Asahina A, Tamaki K.
    • Organizer
      The 31st annual meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591088
  • 1.  TAMAKI Kunihiko (30010432)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 2.  WATANABE Takahiro (30280960)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  NAKAMURA Kohichiro (60175502)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KOMINE Mayumi (00282632)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  TADA Yayoi (00334409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  YASAKA Nami (00220129)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SAEKI Hidehisa (80235093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  中川 秀己 (20114580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  徳永 勝士 (40163977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  柿沼 誉 (30332604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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