KAWAGUCHI Makoto 川口誠

… Alternative Names

川口誠カワグチマコト

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Researcher Number	50204699
Affiliation (based on the past Project Information) *help	2019 – 2023: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2016 – 2018: 名古屋市立大学, 大学院医学研究科, 研究員 2011 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 研究員 2007 – 2010: Nagoya City University, 大学院・医学研究科, 研究員 2006: 名古屋市立大学, 大学院医学研究科, 研究員 … More 2004: Toyama Medical and Pharmaceutical University, Faculty of Medicine, Department of Pathology, Assistant Professor, 医学部, 助手 2000 – 2002: 富山医科薬科大学, 医学部, 助手 1989 – 1990: 富山医科薬科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Urology / Experimental pathology / General medical chemistry Except Principal Investigator Orthopaedic surgery / Experimental pathology / Tumor biology / Gastroenterology / Human pathology / Human pathology
Keywords	Principal Investigator ATBF1 / ZFH4 / ATPase / ジンクフィンガー / ホメオドメイン / 悪性度 / 前立腺癌 / 肺胞 / うっ血 / オスマウス … More / Collagen Type III / Collagen Type I / 全身うっ血 / 心不全 / AF / 川崎病 / 肺血栓塞栓症 / 脳梗塞 / SNP / Central nervous System / Zinc Finger / Homeodomain / 中枢神経 / AFP-producing gastric cancer / ZFH-4 / zinc finger / homeodomain / DNA結合特異性 / AFP産生胃癌 / 転写因子 / 神経発生 / 免疫組織化学 / 膀胱癌 / タンパク分断化 / 癌悪性度 / malignant progression / immunohistochemistry / urothelial carcinoma / Overall survival / 免疫組織科学 / 核での局在 / 膀胱表在癌 / ATBF1 (ZFHX3) / 核移行 / 病理学 / 癌 … More Except Principal Investigator genomic hybridization / sarcoma / gene analysis / metastasis / fibrosarcoma / Klotho / FGF / knockout mouse / 転写因子 / ATBF1 / metastasisi / kidney / ZFH transcription factor / development / brain / platelet-derived growth factor / ノックアウト / 脳 / Conditional knockout / 神経伝達 / 高次脳機能 / conditional knockout / 受容体 / 再生 / apoptosis / マウス / 腎臓 / 発達 / 神経 / 血小板由来増殖因子 / 性ホルモン / 肺癌 / ATBF1(ZFHX3) / 核・細胞質移行 / RUNX3 / 転写制御因子 / p53 / 癌抑制因子 / 胃癌 / アスベスト / 核移行シグナル / 細胞内局在 / 中皮腫 / 多核巨細胞 / モノクロ-ナル抗体 / ライソザイム陽性細胞 / S-100蛋白陽性細胞 / 樹状細胞 / マクロファ-ジ系細胞 / 掌蹠膿疱症 / 扁桃病巣感染症 / Macrophage / Interdigitating cell / Langerhans cell / Helper T cell / Palmoplantal pustulosis / Tonsil / Focal infection Less

Development of a diagnostic method for prostate cancer malignancy using intracellular localization of tumor suppressor ATBF1 as a biomarkerPrincipal Investigator
- Principal Investigator
  
  Kawaguchi Makoto
- Project Period (FY)
  2016 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagoya City University
Analysis of sex hormones derived signaling in lung cancer
- Principal Investigator
  
  INOUE Masaaki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  University of Occupational and Environmental Health, Japan
A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggest malignant progressionPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Makoto
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagoya City University
The significance of nuclear translocation of transcriptional regulatory factor & tumor suppressor, ATBF1, for the malignant nature of gastric cancer.
- Principal Investigator
  
  KATAOKA Hiromi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University
Analysis of the mechanism concerning ATBF1 distribution and altered malignant potential in bladder cancerPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagoya City University
中皮腫の細胞内異常シグナル
- Principal Investigator
  
  MIURA Yutaka
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Nagoya City University
EXPRESSION ANALYSIS OF TRANSCRIPTION FACTOR, ATBF1 AND ZFH4 IN NORMAL DEVELOPING RAT BRAINPrincipal Investigator
- Principal Investigator
  
  SAKATA Nobuo, 川口誠
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  SHOWA PHARMACEUTICAL UNIVERSITY
  Toyama Medical and Pharmaceutical University
Genetic aberrations in the metastatic process and its control -mouse sarcoma and human sarcoma cells-
- Principal Investigator
  
  KANAMORI Masahiko
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Functional analysis on the role of platelet-derived growth factor in CNS development after birth using knockout model.
- Principal Investigator
  
  SASAHARA Masakiyo
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Analysis of DNA binding specificity in homeodomains (1-4) of ATBF1Principal Investigator
- Principal Investigator
  
  KAWAGUCHI Makoto
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
扁桃病巣感染症とみなされる掌蹠膿疱症の免疫病理学的解析
- Principal Investigator
  
  小泉富美朝
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Toyama Medical and Pharmaceutical University

All 2017 2016 2015 2013 2011 2010 2009 2008 2007

All Journal Article Presentation Patent

[Journal Article] Expression and subcellular localization of AT motif binding factor 1 in colon tumours.2017
- Author(s)
  Kataoka H, Miura Y, Kawaguchi M, Suzuki S, Okamoto Y, Ozeki K, Shimura T, Mizoshita T, Kubota E, Tanida S, Takahashi S, Asai K, Joh T.
- Journal Title
  
  Mol Med Rep
  
  Volume: 16 Issue: 3 Pages: 3095-3102
- DOI
  10.3892/mmr.2017.7016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10913, KAKENHI-PROJECT-16K11024, KAKENHI-PROJECT-17K11020, KAKENHI-PROJECT-15K19343
[Journal Article] A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression.2016
- Author(s)
  Kawaguchi M, Hara N, Bilim V, Koike H, Suzuki M, Kim TS, Gao N, Dong Y, Zhang S, Fujinawa Y, Yamamoto O, Ito H, Tomita Y, Naruse Y, Sakamaki A, Ishii Y, Tsuneyama K, Inoue M, Itoh J, Yasuda M, Sakata N, Jung CG, Kanazawa S, Akatsu H, Minato H, Nojima T, Asai K, Miura Y.
- Journal Title
  
  BMC Cancer.
  
  Volume: 16 Issue: 1 Pages: 805-805
- DOI
  10.1186/s12885-016-2845-5
- NAID
  120006814095
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460660, KAKENHI-PROJECT-26461470, KAKENHI-PROJECT-15K06714, KAKENHI-PROJECT-16K11024
[Journal Article] ATBF1 is a novel amyloid-β protein precursor (AβPP) binding protein that affects AβPP expression.2015
- Author(s)
  Uhm KO, Kim MJ, Kawaguchi M, Akatsu H, Miura Y, Misumi S, Hida H, Choi EK, Kim YS, Michikawa M, Jung CG
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 43(1) Pages: 243-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592343
[Journal Article] 胃癌の胃型腸型粘液形質制御における転写因子型癌抑制因子ATBF1の役割2010
- Author(s)
  片岡洋望, 三浦裕, 馬淵元志, 森義徳, 志村貴也, 溝下勤, 谷田諭史, 神谷武, 川口誠, 城卓志
- Journal Title
  
  PROGRESS IN MEDICINE Vol.30(3)
  
  Pages: 787-790
- Data Source
  KAKENHI-PROJECT-20590731
[Journal Article] Tumor suppressor, AT motif binding factor 1 (ATBF1), translocates to the nucleus with runt domain transcription factor 3 (RUNX3) in response to TGF・β signal transduction.2010
- Author(s)
  Mabuchi M, Kataoka H, Miura Y, Kim TS, Kawaguchi M, Ebi M, Tanaka M, Mori Y, Kubota E, Mizushima T, Shimura T, Mizoshita T, Tanida S, Kamiya T, Asai K, Joh T.
- Journal Title
  
  Biochem Biophys Res Commun. 23;398(2)
  
  Pages: 321-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590731
[Journal Article] Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer2007
- Author(s)
  Mori Y, Kataoka H, Miura Y, Kawaguchi M, Kubota E, Ogasawara N, Oshima T, Tanida S, Sasaki M, Ohara H, Mizoshita T, Tatematsu M, Asai K, Joh T.
- Journal Title
  
  Int J Cancer 121
  
  Pages: 241-247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591867
[Patent] 抗ATBF1抗体及びその用途2009
- Inventor(s)
  三浦裕川口誠
- Industrial Property Rights Holder
  (財)名古屋産業科学研究所
- Industrial Property Number
  2009-062180
- Filing Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-18659099
[Patent] 抗ATBF1抗体及びその用途2009
- Inventor(s)
  川口誠、三浦裕
- Industrial Property Rights Holder
  (財)名古屋産業科学研究所
- Industrial Property Number
  2009-062180
- Filing Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19591867
[Patent] 抗ATBF1抗体及びその用途2009
- Inventor(s)
  三浦裕川口誠
- Industrial Property Rights Holder
  (財)名古屋産業科学研究所
- Industrial Property Number
  2009-062180
- Filing Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19591867
[Presentation] 初回TUR膀胱癌細胞の、ATBF1細胞内局在変化により、膀胱癌患者の全生存率、非再発生存率を予測出来る2013
- Author(s)
  川口誠、三浦裕
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌キャッスル
- Data Source
  KAKENHI-PROJECT-23592343
[Presentation] The expression of ATBF1 is in proportion to the expression of estrogen receptor in lung cancer cells2013
- Author(s)
  Masaaki Inoue, Makoto Kawaguchi, Junya Fukuoka, Yutaka Miura
- Organizer
  15^<th> World Conference on Lung Cancer
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24650624
[Presentation] The expression of ATBF1 is in proportion to the expression of estrogen receptor in lung cancer cells2013
- Author(s)
  Masaaki Inoue, Makoto Kawaguchi, Junya Fukuoka, Yutaka Miura
- Organizer
  15th World Conference on Lung Cancer
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24650624
[Presentation] Fragmentation of ATBF1 shows distinct alteration of its subcellular localization suggesting malignancy of bladder cancer cells2011
- Author(s)
  川口誠
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23592343
[Presentation] 遺伝子発現プロファイルを用いたアルゴリズム分析による肺がん培養細胞の分類2008
- Author(s)
  渡辺貴志、三浦知弘、井上政昭、川口誠、降旗千恵
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学学会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19591867
[Presentation] AβはATBF1の発現を上昇させ神経細胞死を誘導する2008
- Author(s)
  鄭且均、川口誠、三浦裕、赤津裕康、金泰善、道川誠
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19591867
[Presentation] P19細胞の神経分化誘における転写調節因子ATBF1による細胞外マトリックス接着関連因子の発現調節 BMB20082008
- Author(s)
  三浦裕、金泰善、鈴木光子、川口誠、鄭且均、浅井清文
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19591867
[Presentation] オリジナルDNA マイクロアレイによるヒト肺がん組織型に特徴的な遺伝子発現の解析2008
- Author(s)
  杉山真未、椿山由香、渡辺貴志、井上政昭、川口誠、降旗千恵
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学学会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19591867
[Presentation] ATBF1 Expression in Primary Lung Cancer2007
- Author(s)
  井上政昭、川口誠、杉尾賢二、安元公正、三浦裕
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591867
[Presentation] ATM/AR の標的因子ATBF1 の細胞内局在制御メカニズム2007
- Author(s)
  鄭且均、川口誠、浅井清文、三浦裕
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591867
[Presentation] ATBF1 expression is a novel indicator for diagnosis of small size lung adenocarcinomas2007
- Author(s)
  Inoue M, Kawaguchi M, Noguchi M, Yasumoto K, Miura M
- Organizer
  American Association for Cancer Research Annual Meeting 2007
- Place of Presentation
  Los Angels, CA, USA
- Data Source
  KAKENHI-PROJECT-19591867

1. MIURA Yutaka (90285198)

# of Collaborated Projects: 6 results

# of Collaborated Products: 14 results
2. SASAHARA Masakiyo (20154015)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SAKATA Nobuo (00170598)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KATAOKA Hiromi (40381785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. JOU Takashi (30231369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. INOUE Masaaki (20330988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. ISHII Yoko (00361949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OYA Takeshi (00343179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUJIMORI Toshihiko (80301274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KANAMORI Masahiko (20204547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OHMORI Kazuo (80303238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GEJO Ryuichi (00359712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小泉富美朝 (70018323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 倉茂洋一 (00126517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 浦本秀隆 (90389445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石澤伸 (40222989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MINATO Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 浅井清文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAGUCHI Makoto 川口 誠

川口 誠 カワグチ マコト

Research Projects

Research Products

Co-Researchers

Development of a diagnostic method for prostate cancer malignancy using intracellular localization of tumor suppressor ATBF1 as a biomarkerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of sex hormones derived signaling in lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggest malignant progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The significance of nuclear translocation of transcriptional regulatory factor & tumor suppressor, ATBF1, for the malignant nature of gastric cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism concerning ATBF1 distribution and altered malignant potential in bladder cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

中皮腫の細胞内異常シグナル

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EXPRESSION ANALYSIS OF TRANSCRIPTION FACTOR, ATBF1 AND ZFH4 IN NORMAL DEVELOPING RAT BRAINPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic aberrations in the metastatic process and its control -mouse sarcoma and human sarcoma cells-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis on the role of platelet-derived growth factor in CNS development after birth using knockout model.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of DNA binding specificity in homeodomains (1-4) of ATBF1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

扁桃病巣感染症とみなされる掌蹠膿疱症の免疫病理学的解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression and subcellular localization of AT motif binding factor 1 in colon tumours.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression.2016

Author(s)

Journal Title

DOI

KAWAGUCHI Makoto 川口誠

川口誠カワグチマコト

[Presentation] 初回TUR膀胱癌細胞の、ATBF1細胞内局在変化により、膀胱癌患者の全生存率、非再発生存率を予測出来る2013