YOSHIMURA Ashio 吉村吾志夫

… Alternative Names

YOSIMURA Ashio 吉村吾志夫

吉村吾志夫ヨシムラアシオ

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Researcher Number	50211660
Other IDs
Affiliation (Current)	2025: 昭和医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2009 – 2011: Showa University, 医学部, 教授 2007: Showa University, Department of Medicne, Associate Professor 2006: 昭和大学, 医学部, 助教授 2003 – 2004: 昭和大学, 医学部, 助教授 2001: SHOWA UNIVERSITY, SCHOOL OF MEDICINE, ASSOCIATE PROFESSOR, 医学部, 助教授 … More 2000: 昭和大, 医学部, 助教授 1997 – 1999: 昭和大学, 医学部, 助教授 1995: 昭和大学, 医学部, 助教授 1993 – 1994: 昭和大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine Except Principal Investigator Kidney internal medicine
Keywords	Principal Investigator メサンギウム細胞 / カルポニン / 糸球体硬化 / 抗Thy-1腎炎 / 増殖性糸球体腎炎 / α平滑筋アクチン / frizzled / 腎不全 / トランスジェニックマウス / 中性カルポニン … More / 糸球体腎炎 / アポトーシス / マクロファージ / ループス腎炎 / IgA腎症 / PCNA(増殖細胞核抗原) / in situ hybridization / PDGF(血小板由来成長因子) / macrophage / aSmooth muscle actin / Streptozocin / Transgenic mouse / Diabetic nephropathy / Neutral calponin / 血管内皮細胞 / 新生血管 / 糖尿病 / ストレプトゾシン / 糖尿病性腎症 / smooth muscle actin / glomerulosclerosis / mesaneial cell / proliferative glomerulonephritis / hypertension / SHE / transgenic rat / basic calponin / 腎障害 / 血管平滑筋細胞 / 平滑筋細胞 / 平滑筋アクチン / 糸球体硬化症 / 高血圧 / SHR / トランスジェニックラット / 塩基性カルポニン / unilateral ureteral obstruction / α-smooth muscle sctin / interstitium / renal fibrosis / myofibroblast / polarity gene / 組織極性 / frizzled遺伝子 / Myofibroblast / 腎間質線維化 / 一側尿管結紮 / 間質 / 腎線維化 / 筋線維芽細胞 / 極性 / hemodialysis therapy / renal failure / glomerulonephritis / oxygen radicals / mesangial cell / telomerase / telomere / senescence / 透析療法 / 活性酸素 / テロメラーゼ / テロメア / 老化 / 心腎相関 / 心腎連関 / 心・腎連関 / 慢性腎臓病 / 線維化 / CVD / CKD / Le^Y抗原 / clusterin / Bax / Bcl-2 / In situ hybridization / Osteonectin / SPARC … More Except Principal Investigator 尿細管壊死 / 抗血小板抗体 / 免疫組織化学 / 塩化第2水銀 / 上皮成長因子 / 急性腎不全 Less

The role of neutral calponin in the relationship between CKD and CVDPrincipal Investigator
- Principal Investigator
  
  YOSHIMURA Ashio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
Suppression of the development of diabetic nephropathy by expression of non-smooth muscle calponinPrincipal Investigator
- Principal Investigator
  
  YOSHIMURA Ashio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
REGULATION OF HYPERTENSION-INDUCED RENAL INJURY BY INDUCTION OF SMOOTH MUSCLE ACTIN BINDING PROTEIN EXPRESSIONPrincipal Investigator
- Principal Investigator
  
  YOSHIMURA Ashio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
TISSUE POLARITY GENE FRIZZLED IS EXPRESSED IN THE INTERSTITIAL MYOFIBROBLASTS IN A RENAL FIBROSIS.Principal Investigator
- Principal Investigator
  
  YOSHIMURA Ashio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
Significance of mesangial cell aging in glomerulonephritisPrincipal Investigator
- Principal Investigator
  
  YOSIMURA Ashio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
糸球体腎炎の進展と制御におけるアポトーシスの意義についての遺伝子レベルからの解明Principal Investigator
- Principal Investigator
  
  吉村吾志夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
低タンパク食によるメサンギウム細胞増殖の制御についての遺伝子レベルからの解析Principal Investigator
- Principal Investigator
  
  吉村吾志夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
糸球体内因性物質によるメサンギウム細胞増殖の制御についての遺伝子レベルからの解明Principal Investigator
- Principal Investigator
  
  吉村吾志夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University
急性腎不全の修復における上皮細胞成長因子の関与についての遺伝子レベルからの解析
- Principal Investigator
  
  飯塚一秀
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Showa University

All 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] Annual Review腎臓20052005
- Author(s)
  渡辺励, 吉村吾志夫
- Total Pages
  240
- Publisher
  中外医学社(分担執筆)(伊藤克己, 他編集)
- Data Source
  KAKENHI-PROJECT-15590860
[Book] 臨床に直結する腎疾患治療のエビデンス2003
- Author(s)
  吉村吾志夫
- Total Pages
  402
- Publisher
  文光堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse.2009
- Author(s)
  Nakayama T, Yoshimura A, Nakagawa T, et al.
- Journal Title
  
  Am J Physiol Renal Physiol 206 :
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse.2009
- Author(s)
  Nakayama T, Yoshimura A, Nakagawa T, et al.
- Journal Title
  
  Am J Physiol Renal Physiol 206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Actin-related protein 3(Arp3)is mutated in proteinuric BUF/Mna rats2008
- Author(s)
  Akiyama K, Morita H, Yoshimura A, 他
- Journal Title
  
  Mamm Genome 19
  
  Pages: 41-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Type B insulin resistance syndrome of systemic lupus erythematosus in a hemodialysis patients.2008
- Author(s)
  Nagayama Y, Yoshimura A, et al.
- Journal Title
  
  Clin Nephrol 69
  
  Pages: 130-134
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] The role of heparin sulfate in the glomerular basement membrane2008
- Author(s)
  Morita H, Yoshimura A, Kimata K
- Journal Title
  
  Kidney Int 73
  
  Pages: 247-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Actin-related protein 3(Arp3)is mutated in proteinuric BUF/Mna rats2008
- Author(s)
  Akiyama K, Morita H, Yoshimura A, et al.
- Journal Title
  
  Mamm Genome 19
  
  Pages: 41-50
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Actin-related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats2008
- Author(s)
  Akiyama K, Morita H, Yoshimura A, et al.
- Journal Title
  
  Mamm Genome 19
  
  Pages: 41-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Heparan sulfate in the glomerular basement membrane.2008
- Author(s)
  Morita H, Yoshimura A, Kimata K
- Journal Title
  
  Kidney Int 73
  
  Pages: 247-248
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Type B insulin resistance syndrome induced by increased activity of systemic Iupus erythematosus in a hemodialysis patient2008
- Author(s)
  Nagayama Y, Yoshimura A, 他
- Journal Title
  
  Clin Nephrol 69
  
  Pages: 130-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Immunohistochemical analysis on serum proteins in nephrons of protein-overload mice by "in vivo cryotechnique"2007
- Author(s)
  Zhou D, Ohno N, Terada N, Li Z, Morita H, Inui K, Yoshimura A, Ohno S
- Journal Title
  
  Histol Histopathol 22
  
  Pages: 137-145
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Immunohistochemical analysis on serum proteins in nephrons of protein-overload mice by “in vivo cryotechnique"2007
- Author(s)
  Zhou D, Yoshimura A, OhnoS, et. al.
- Journal Title
  
  Histol Histopatho 22
  
  Pages: 137-145
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Immunohistochemical analysis on serum proteins in nephrons of protein-overload mice by "in vivo cryotechnique".2007
- Author(s)
  Zhou D, Yoshimura A, Ohno S, et. al.
- Journal Title
  
  Histol Histopatho 22
  
  Pages: 137-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Glomerulonephritis in sarcoidosis2006
- Author(s)
  Morita H, Yoshimura A
- Journal Title
  
  Clin Exp Nephrol 10
  
  Pages: 85-86
- NAID
  10017320421
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] Application of periodic acid-Schiff fluorescence emission for immunohistochemistry of living mouse renal glomeruli by an "in vivo cryotechnique"2006
- Author(s)
  Li Z, Ohno N, Terada N, Zhou D, Yoshimura A, Ohno S
- Journal Title
  
  Arch Histol Cytol 69
  
  Pages: 147-161
- NAID
  10020623460
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] The proliferation-associated antigen Ki-67 is a useful marker for evaluating disease activity in human IgA nephropathy2006
- Author(s)
  Jiang W, Zhou D, Inui K, Watanabe S, Morita H, Yoshimura A
- Journal Title
  
  Showa Univ J Med Sci 18
  
  Pages: 117-124
- NAID
  130004190197
- Data Source
  KAKENHI-PROJECT-18590908
[Journal Article] 食事療法2004
- Author(s)
  吉村吾志夫, 原恭子
- Journal Title
  
  最新医学(別冊) 別冊23
  
  Pages: 89-96
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Prognosis and risk factors for idiopathic membranous nephropathy with nephrotic syndrome in Japan.2004
- Author(s)
  Shiiki H, Saito T, Nishitani Y, Mitarai T, Yorioka N, Yoshimura A, et. al.
- Journal Title
  
  Kidney Int 65
  
  Pages: 1400-1407
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Prognosis and risk factors for idiopathic membranous nephropathy with nephrotic syndrome in Japan2004
- Author(s)
  Shiiki H, Saito T, Nishitani Y, Mitarai T, Yorioka N, Yoshimura A, et. al.
- Journal Title
  
  Kidney Int 65
  
  Pages: 1400-1407
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] 微小変化型ネフローゼ症候群2004
- Author(s)
  宇田晋, 吉村吾志夫
- Journal Title
  
  日本臨床 62
  
  Pages: 1829-1836
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Collagenofibrotic glomerulopathy with awidespread expression of thype-V collagen.2003
- Author(s)
  Morita H, Yoshimura A, et. al.
- Journal Title
  
  VirchowArch 442
  
  Pages: 163-168
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] The long-term effect of high phosphate intake on parathyroid cell proliferation in chronic renal failure rats.2003
- Author(s)
  X. Zhong, A. Yoshimura, et. al.
- Journal Title
  
  Showa Univ J Med Sci 15
  
  Pages: 257-264
- NAID
  130004190120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Effect of the Lathyrogene,β-aminopropionitrile on rats with Adriamycin nephropathy2003
- Author(s)
  Liu Y, Yoshimura A, et. al.
- Journal Title
  
  Showa Univ JMed Sci 15
  
  Pages: 323-329
- NAID
  130004190128
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Combination treatment of angiotensin-II receptor Mocker and angiotensin converting enzyme inhibitor in non-diabetic renal disease(COOPERATE):a randomized conhrolled tiral2003
- Author(s)
  Nakao N, Yoshimura A, et. al.
- Journal Title
  
  Lancet 361
  
  Pages: 117-124
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Effect of the Lathyrogene, j3 -aminopropionitrile on rats with Adriamycin nephropathy.2003
- Author(s)
  Liu Y, Yoshimura A, et. al.
- Journal Title
  
  Showa Univ JMed Sci 15
  
  Pages: 323-329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Collagenofibrotic glomerulopathy with a widespread expression of thype-V collagen2003
- Author(s)
  Morita H, Yoshimura A, et. al.
- Journal Title
  
  Virchow Arch 442
  
  Pages: 163-168
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Effect of nonsupplemented low-protein-diet on very late stage CRF2003
- Author(s)
  Ideura T, Yoshimura A, et. al.
- Journal Title
  
  Am J Kidney Dis 41(Supp)
  
  Pages: 831-834
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Effect of nonsupplemented low-protein-diet on very late stage CRF.2003
- Author(s)
  Ideura 1, Yoshimura A, et. al.
- Journal Title
  
  Am J Kidney Dis 41(Supp)
  
  Pages: 831-834
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Combination treatment of angiotensin-Il receptor blocker and angiote-sin converting enzyme inhibitor in non-diabetic renal disease(COOPERATE) : arandomized controlled tiral.2003
- Author(s)
  Nakao N, Yoshimura A, et. al.
- Journal Title
  
  Lancet 361
  
  Pages: 117-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] The long-term effect of high phosphate intake on parathyroid cell proliferation in chronic renal failure rats2003
- Author(s)
  X. Zhong, A. Yoshimura, et. al.
- Journal Title
  
  Showa Univ J Med Sci 15
  
  Pages: 257-264
- NAID
  130004190120
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590860
[Journal Article] Heparan sulfate in the glomerular basement membrane.
- Author(s)
  Morita H, Yoshimura A, Kimata K.
- Journal Title
  
  Kidney Int 73
  
  Pages: 247-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590908
[Presentation] Neutral calponinによる糖尿病の腎組織障害抑制2011
- Author(s)
  乾聖子、吉村吾志夫、他
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21591041
[Presentation] Neutral calponin (calponin-h2, CN2)による糖尿病(DM)の腎組織障害抑制2011
- Author(s)
  乾聖子、吉村吾志夫, 他
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21591041
[Presentation] Precedent anti-inflammation and suppression of subsequent interstitial fibrosis in the kidney by non-smooth muscle calponin (calponin-h2) in diabetic mice are independent of both glucose metabolism and expression of its related molecules.2010
- Author(s)
  K.Inui, T.Nakayama, Y.Inoue, A.Yoshimura
- Organizer
  Renal Week 2010 of the American Society of Nephrology
- Place of Presentation
  Colorado (Denver)
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21591041
[Presentation] Precedent anti-inflammation and suppression of subsequent interstitial fibrosis in the kidney by non-smooth muscle calponin(calponin-h2) in diabetic mice are independent of both glucose metabolism and expression of its related molecules.2010
- Author(s)
  K, Inui, T. Nakayama, Y. Inoue, A. Yoshimura
- Organizer
  米国腎臓学会
- Place of Presentation
  アメリカ(デンバー)
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21591041
[Presentation] Non-smooth muscle calponin suppresses active interstitial inflammation and subsequent fibrosis in the kidney after unilateral ureteral obstruction.2009
- Author(s)
  K. Inui, H. Morita, A. Yoshimura et al
- Organizer
  米国腎臓学会
- Place of Presentation
  アメリカ(サンディエゴ)
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21591041
[Presentation] Non-smooth muscle calponin suppresses active interstitial inflammation and subsequent fibrosis in the kidney after unilateral ureteral2009
- Author(s)
  K.Inui, H.Morita, A.Yoshimura, et al
- Organizer
  米国腎臓学会
- Place of Presentation
  San Diego(USA)
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21591041
[Presentation] Regulation of active inflammation in early phase of unilateral ureteral obstruction by eplerenone,novel selective aldosterone blocker,is critical for suppression of subsequent development of fibrosis2007
- Author(s)
  Inui K, Chen H, Yoshimura A, 他
- Organizer
  2007 Annual Meeting of the Amer Society of Nephrol
- Place of Presentation
  San Francisco
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18590908

1. 飯塚一秀 (60255833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 岩崎滋樹 (00241026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. INOUE Yoshihiko (20343494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKASHASHI Katsuhito (40211338)

# of Collaborated Projects: 1 results

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YOSHIMURA Ashio 吉村 吾志夫

YOSIMURA Ashio 吉村 吾志夫

吉村 吾志夫 ヨシムラ アシオ

Research Projects

Research Products

Co-Researchers

The role of neutral calponin in the relationship between CKD and CVDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Suppression of the development of diabetic nephropathy by expression of non-smooth muscle calponinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

REGULATION OF HYPERTENSION-INDUCED RENAL INJURY BY INDUCTION OF SMOOTH MUSCLE ACTIN BINDING PROTEIN EXPRESSIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TISSUE POLARITY GENE FRIZZLED IS EXPRESSED IN THE INTERSTITIAL MYOFIBROBLASTS IN A RENAL FIBROSIS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Significance of mesangial cell aging in glomerulonephritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糸球体腎炎の進展と制御におけるアポトーシスの意義についての遺伝子レベルからの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低タンパク食によるメサンギウム細胞増殖の制御についての遺伝子レベルからの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糸球体内因性物質によるメサンギウム細胞増殖の制御についての遺伝子レベルからの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

急性腎不全の修復における上皮細胞成長因子の関与についての遺伝子レベルからの解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Annual Review腎臓20052005

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床に直結する腎疾患治療のエビデンス2003

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse.2009

Author(s)

Journal Title

Description

Data Source

[Journal Article] Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse.2009

Author(s)

Journal Title

Description

YOSHIMURA Ashio 吉村吾志夫

YOSIMURA Ashio 吉村吾志夫

吉村吾志夫ヨシムラアシオ