Mayeda Akila 前田明

… Alternative Names

MAYEDA Akila 前田明

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Researcher Number	50212204
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 腫瘍医学研究センター, 客員教授
Affiliation (based on the past Project Information) *help	2024: 藤田医科大学, 腫瘍医学研究センター, 名誉教授 2023: 藤田医科大学, がん医療研究センター, 名誉教授 2023: 藤田医科大学, がん医療研究センター, 客員教授 2021 – 2023: 藤田医科大学, 医科学研究センター, 教授 2018 – 2021: 藤田医科大学, 総合医科学研究所, 教授 2008 – 2017: Fujita Health University, 総合医科学研究所, 教授
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Tumor diagnostics / System genome science / Living organism molecular science / Biological Sciences / 基礎ゲノム科学 Except Principal Investigator General surgery / Basic Section 56030:Urology-related / Genome biology / 基礎ゲノム科学
Keywords	Principal Investigator スプライシング / 癌 / 遺伝子発現調節 / mRNA / EJC / TSG101 / スプライシング完了機構 / 品質管理機構 / 遺伝子発現 / mRNA品質管理 … More / mRNA再スプライシング / 遺伝子発現制御 / イントロン / SAP30BP / RBM17 (SPF45) / mRNA前駆体 / エキシトロン / mRNA前駆体スプライシング / エクソン接合部複合体（EJC） / 非翻訳RNA / MIR / ciRS-7 / 環状RNA / ノンコーディングRNA / プロテオーム / p53 / RBM4a / PSAP / RNPS / eIF4A3 / mRNA品質管理機構 / Presenilin-2 / アルツハイマー病 / Presenillin-2 / HMGA1 / 異常スプライシング / 遺伝子 / 潜在的スプライス部位 / FHIT遺伝子 / TSG101遺伝子 / ジストロフィン遺伝子 / RNase R / 投縄状RNA / 選択的スプライス部位 … More Except Principal Investigator 選択的スプライシング / エストロゲン受容体 / 乳癌 / データーベース / 進化 / イントロン / RNAスプライシング / データベース / 膀胱全摘除術 / 膀胱癌 / 遺伝子パネル検査 / 血中循環癌細胞 / 術後イレウス / 腫瘍制御 / 鏡視下手術 / ロボット支援膀胱全摘除術 / 筋層浸潤性尿路上皮癌 / ヒト遺伝子 / 潜在的スプライシング部位 / 突然変異 / 人類進化 / 制御機構 / 脳 / 遺伝子発現 / スプライシング / RNA結合蛋白質 / 癌遺伝子産物 / 乳腺外科学 / HMGA1a / ストロゲン受容体 / 内分泌外科学 / スプライセオソーム / H-InvDB / アノテーション / オロソログ / 転写産物 / ヒトゲノム / pre-mRNA splicing / イントロン長 / ゲノム進化・再編 Less

The discovery of new essential splicing factors restructure a set of human intronsPrincipal Investigator
- Principal Investigator
  
  前田明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Fujita Health University
Understanding the mechanism underlying splicing termination with mRNA re-splicing repressorPrincipal Investigator
- Principal Investigator
  
  Mayeda Akila
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Fujita Health University
鏡視下膀胱全摘除術後の特異的腫瘍再発に関連する腫瘍細胞の生化学的解析と術式の検討
- Principal Investigator
  
  白木良一
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fujita Health University
Exploring the implications of cancer-specific mRNA re-splicing events in the robustness and catastrophe of gene expression systemPrincipal Investigator
- Principal Investigator
  
  Mayeda Akila
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Fujita Health University
Mechanisms to make important noncoding RNAs from dispensable coding RNAsPrincipal Investigator
- Principal Investigator
  
  Mayeda Akila
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  System genome science
- Research Institution
  Fujita Health University
Search for the cause of proteomic disorder without genomic mutations in the global mis-regulation of splicingPrincipal Investigator
- Principal Investigator
  
  MAYEDA Akila
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnostics
- Research Institution
  Fujita Health University
Global disorder of splicing caused by oncogene product HMGA1Principal Investigator
- Principal Investigator
  
  MAYEDA Akila
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Fujita Health University
Exploring a novel therapy of hormone-resistant breast cancer by short RNA
- Principal Investigator
  
  OHE Kenji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Bioinformatic and molecular biological study on ultra-short introns
- Principal Investigator
  
  SHIMADA Makoto
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Fujita Health University
ｍＲＮＡの再スプライシング現象から探る未知のｍＲＮＡ品質管理機構Principal Investigator
- Principal Investigator
  
  前田明
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Fujita Health University
Bioinformatic and molecular biological study on ultra-short introns
- Principal Investigator
  
  SHIMADA Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Fujita Health University
Regulation of Estrogen Receptor Alpha through novel function of HMGA1a.-Towards a novel breast cancer therapy-
- Principal Investigator
  
  OHE Kenji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Fujita Health University
ヒトゲノムに散在する巨大遺伝子の発現機構:イントロン内スプライシング予想の証明Principal Investigator
- Principal Investigator
  
  前田明
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Fujita Health University

[Book] スプライシング制御① mRNA転写・プロセシング・核外輸送・品質管理における相互連携の重要性: mRNAの制御機構の解明と治療薬・ワクチンへの活用2023
- Author(s)
  藤田賢一, 堀史人, , 鵜飼生望, 前田明, 増田誠司
- Total Pages
  411
- Publisher
  技術情報協会
- ISBN
  9784861049378
- Data Source
  KAKENHI-PROJECT-21K06024
[Book] 実験医学特集号「coding RNAルネッサンス」2016
- Author(s)
  片岡直行, 前田明
- Total Pages
  143
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16H04705
[Book] 実験医学特集号「coding RNAルネッサンス」2016
- Author(s)
  片岡直行, 前田明
- Total Pages
  142
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16K14659
[Book] Chapter 30 : ln vitro splicing assays (Alternative pre-mRNA splicing : Theory and protocols)2012
- Author(s)
  Mayeda, A., Krainer, A.R. (Stamm, S., Luhrmann, R., eds.)
- Total Pages
  10
- Publisher
  Wiley-VCH Verlag, Weinheim, Germany
- Data Source
  KAKENHI-PUBLICLY-23112722
[Book] In vitro splicing assays. In Alternative pre-mRNA splicing : Theory and Protocols (S. Stamm and R Luhrmann, eds.)2012
- Author(s)
  Akila Mayeda, Adrian R. Krainer
- Total Pages
  10
- Publisher
  Wiley-VCH Verlag, Weinheim, Germany
- Data Source
  KAKENHI-PROJECT-24310161
[Book] Chapter 30: In vitro splicing assays (Alternative pre-mRNA splicing: Theory and Protocols)2012
- Author(s)
  Mayeda, A., Krainer, A.R. (Stamm, S., Luhrmann, R., eds.)
- Total Pages
  10
- Publisher
  Wiley-VCH Verlag, Weinheim, Germany
- Data Source
  KAKENHI-PUBLICLY-23112722
[Book] Alternative pre-mRNA splicing : Theory and protocols Chaper 30 In vitro splicing assays2012
- Author(s)
  A.Mayeda, A.R.Krainer (Edited by S.Stam, et al.)
- Publisher
  Wiley-Blackwell, Weinheim, Germany
- Data Source
  KAKENHI-PUBLICLY-23112722
[Book] 実験医学増刊:拡大・進展を続けるRNA研究の最先端第3章2.癌の発生と進行に関わるmRNA前駆体スプライシングの破綻2010
- Author(s)
  亀山俊樹、前田明
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20651051
[Journal Article] Terminal regions of UAP56 and URH49 are required for their distinct complex formation functioning to an essential role in mRNA processing and export.2024
- Author(s)
  K-I. Fujita, T. Yamazaki, A. Mayeda, S. Masuda
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 703 Pages: 149682-149682
- DOI
  10.1016/j.bbrc.2024.149682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K19078, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-23K23809
[Journal Article] Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes.2024
- Author(s)
  K-I. Fujita, M. Ito, M. Irie, K. Harada, N. Fujiwara, Y. Ikeda, H. Yoshioka, T. Yamazaki, M. Kojima, B. Mikami, A. Mayeda, S. Masuda
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 455-455
- DOI
  10.1038/s41467-023-44217-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K19078, KAKENHI-PROJECT-21K15538, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-23K23809
[Journal Article] RBM17 expression Is associated with the efficacy of ICI monotherapy in NSCLC with low PD-L1 expression.2023
- Author(s)
  H. Nagamine, M. Yashiro, N. Yoshimoto, M. Izumi, A. Sugimoto, K. Nakahama, K. Ogawa, Y. Matsumoto, K. Sawa, Y. Tani, H. Kaneda, S. Mitsuoka, K. Yamada, T. Watanabe, K. Aasai, K. Fukumura, A. Mayeda, T. Kawaguchi
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 10 Pages: 4663-4672
- DOI
  10.21873/anticanres.16662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Journal Article] SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns2023
- Author(s)
  Fukumura Kazuhiro、Sperotto Luca、Seu? Stefanie、Kang Hyun-Seo、Yoshimoto Rei、Sattler Michael、Mayeda Akila
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 12 Pages: 113534-113534
- DOI
  10.1016/j.celrep.2023.113534
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05565, KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Journal Article] SAP30BP interacts with SPF45/RBM17 to promote splicing in a distinct subset of human short introns.2022
- Author(s)
  K. Fukumura, L. Sperotto, H-S. Kang, S. Seuss, R. Yoshimoto, M. Sattler, A. Mayeda
- Journal Title
  
  BioRxiv
  
  Volume: 2022 Pages: 522300-522300
- DOI
  10.1101/2022.12.30.522300
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-22K05565
[Journal Article] Epstein-Barr virus enhances cancer-specific aberrant splicing.2022
- Author(s)
  H.H. Chua, T. Kameyama, A. Mayeda, T.H. Yeh
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 23 Issue: 5 Pages: 2516-2516
- DOI
  10.3390/ijms23052516
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024
[Journal Article] 「イントロンの長さ」の不可思議に端を発する新しいスプライシング機構の発見.2022
- Author(s)
  福村和宏, 前田明
- Journal Title
  
  生化学
  
  Volume: 94 Pages: 806-813
- Data Source
  KAKENHI-PROJECT-21K06024
[Journal Article] SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns2021
- Author(s)
  Fukumura Kazuhiro、Yoshimoto Rei、Sperotto Luca、Kang Hyun-Seo、Hirose Tetsuro、Inoue Kunio、Sattler Michael、Mayeda Akila
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-021-24879-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05563, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PROJECT-21K06018, KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Journal Article] The exon junction complex core represses cancer-specific mature mRNA re-splicing: A potential key role in terminating splicing.2021
- Author(s)
  Y. Otani, K.-i. Fujita, T. Kameyama, A. Mayeda
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 12 Pages: 6519-6519
- DOI
  10.3390/ijms22126519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K15538
[Journal Article] スプライシングと抗がん剤耐性.2021
- Author(s)
  福村和宏, 前田明
- Journal Title
  
  細胞
  
  Volume: 53 Pages: 900-901
- Data Source
  KAKENHI-PROJECT-21K06024
[Journal Article] SPF45/RBM17-dependent splicing implicated in multidrug resistance in cancer chemotherapy.2021
- Author(s)
  K. Fukumura, J.P. Venables, A. Mayeda
- Journal Title
  
  Mol. Cell. Oncol.
  
  Volume: 8 Issue: 6 Pages: 1996318-1996318
- DOI
  10.1080/23723556.2021.1996318
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Journal Article] Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats2020
- Author(s)
  Yoshimoto Rei、Rahimi Karim、Hansen Thomas B.、Kjems J?rgen、Mayeda Akila
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 7 Pages: 101345-101345
- DOI
  10.1016/j.isci.2020.101345
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05563, KAKENHI-PROJECT-21K06024
[Journal Article] Component of splicing factor SF3b plays a key role in translational control of polyribosomes on the endoplasmic reticulum2019
- Author(s)
  Ueno Tomonori、Taga Yuki、Yoshimoto Rei、Mayeda Akila、Hattori Shunji、Ogawa-Goto Kiyoko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 19 Pages: 9340-9349
- DOI
  10.1073/pnas.1901742116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05563, KAKENHI-PROJECT-16H04705
[Journal Article] A distinct subset of human short introns: U2AF heterodimer is replaced by SPF45 (RBM17) as general splicing factor2019
- Author(s)
  K. Fukumura, R. Yoshimoto, T. Hirose, K. Inoue, A. Mayeda
- Journal Title
  
  bioRxiv
  
  Volume: - Pages: 784868-784868
- DOI
  10.1101/784868
- Open Access
- Data Source
  KAKENHI-PROJECT-16H04705
[Journal Article] Cancer-Specifically Re-Spliced TSG101 mRNA Promotes Invasion and Metastasis of Nasopharyngeal Carcinoma2019
- Author(s)
  Chua Huey-Huey、Kameyama Toshiki、Mayeda Akila、Yeh Te-Huei
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 3 Pages: 773-773
- DOI
  10.3390/ijms20030773
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07182, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-16H04705
[Journal Article] RNPS1 suppresses errors in pre-mRNA splicing: A key factor for mRNA quality control2018
- Author(s)
  K. Fukumura, K. Inoue, A. Mayeda
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 496 Issue: 3 Pages: 921-926
- DOI
  10.1016/j.bbrc.2018.01.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04705
[Journal Article] Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13).2016
- Author(s)
  Abe A, Mizuta S, Okamoto A, Yamamoto Y, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  International journal of laboratory hematology
  
  Volume: 38(2) Issue: 2 Pages: 15-18
- DOI
  10.1111/ijlh.12450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] 環状RNA（circRNA）2016
- Author(s)
  芳本玲, 前田明
- Journal Title
  
  ノンコーディングRNA―RNA分子の全体像を俯瞰する（DOJIN BIOSCIENCEシリーズ）
  
  Volume: 25 Pages: 271-279
- Data Source
  KAKENHI-PROJECT-16K14659
[Journal Article] MALAT1 long non-coding RNA in cancer.2016
- Author(s)
  Yoshimoto R, Mayeda A, Yoshida M, Nakagawa S.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1859 Issue: 1 Pages: 192-199
- DOI
  10.1016/j.bbagrm.2015.09.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26113005, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161
[Journal Article] ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9.2016
- Author(s)
  Abe A, Yamamoto Y, Iba S, Kanie T, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Mizuta S, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Genes, chromosomes & cancer
  
  Volume: 55(3) Issue: 3 Pages: 242-250
- DOI
  10.1002/gcc.22327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot2016
- Author(s)
  Hitoshi Suzuki, Yoshitsugu Aoki, Toshiki Kameyama, Takashi Saito, Satoru Masuda, Jun Tanihata, Tetsuya Nagata, Akila Mayeda, Shin’ichi Takeda, Toshifumi Tsukahara
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 17 Issue: 10 Pages: 1722-1722
- DOI
  10.3390/ijms17101722
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290072, KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-16K14659
[Journal Article] 生命現象を支える多種多様の蛋白質が正しく作られる仕組：遺伝子に隠されたスプライシング調節暗号を解く.2015
- Author(s)
  前田明
- Journal Title
  
  DNA多型
  
  Volume: 23 Pages: 3-8
- Data Source
  KAKENHI-PROJECT-25640081
[Journal Article] がん細胞で異常なタンパク質が作られる仕組みを「mRNA再スプライシング」現象から探る.2015
- Author(s)
  亀山俊樹, 前田明
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 22-26
- NAID
  130007447869
- Data Source
  KAKENHI-PROJECT-25640081
[Journal Article] 生命現象を支える多種多様の蛋白質が正しく作られる仕組：遺伝子に隠されたスプライシング調節暗号を解く.2015
- Author(s)
  前田明
- Journal Title
  
  DNA多型
  
  Volume: 23 Pages: 3-8
- Data Source
  KAKENHI-PROJECT-24310161
[Journal Article] NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214.2015
- Author(s)
  Abe A, Yamamoto Y, Iba S, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Kanie T, Tsuzuki M, Akatsuka Y, Mizuta S, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Cytogenetic and genome research
  
  Volume: 146(4) Issue: 4 Pages: 279-284
- DOI
  10.1159/000441464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161
[Journal Article] Identification and Validation of Evolutionarily Conserved Unusually Short Pre-mRNA Introns in the Human Genome2015
- Author(s)
  Makoto K. Shimada,Noriko Sasaki-Haraguchi, and Akila Mayeda
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 16 Issue: 5 Pages: 10376-10388
- DOI
  10.3390/ijms160510376
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510271, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161
[Journal Article] がん細胞で異常なタンパク質が作られる仕組みを「mRNA再スプライシング」現象から探る.2015
- Author(s)
  亀山俊樹, 前田明
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 22-26
- NAID
  130007447869
- Data Source
  KAKENHI-PROJECT-24310161
[Journal Article] Identification and Validation of Evolutionarily Conserved Unusually Short Pre-mRNA Introns in the Human Genome2015
- Author(s)
  Shimada MK, Sasaki-Haraguchi N, Mayeda, A
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510271
[Journal Article] がん細胞で異常なタンパク質が作られる仕組みを「mRNA再スプライシング」現象から探る．2015
- Author(s)
  亀山俊樹、前田明
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 22-26
- NAID
  130007447869
- Data Source
  KAKENHI-PROJECT-25640081
[Journal Article] がん細胞で異常なタンパク質が作られる仕組みを「mRNA再スプライシング」現象から探る．2015
- Author(s)
  亀山俊樹, 前田明
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 22-26
- NAID
  130007447869
- Data Source
  KAKENHI-PROJECT-24310161
[Journal Article] HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA.2013
- Author(s)
  Rahman, M. A., Masuda, A., Ohe, K., Ito, M. , Hutchinson, D. O., Mayeda, A., Engel, A. G. and Ohno, K.
- Journal Title
  
  Sci. Rep.
  
  Volume: 3 Issue: 1 Pages: 2931-2931
- DOI
  10.1038/srep02931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24591920, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25670164
[Journal Article] Nested introns in an intron : Evidence of multi-step splicing in a large intron of the human dystrophin pre-mRNA.2013
- Author(s)
  Suzuki, H., Kameyama, T., Ohe, K. Tsukahara, T., Mayeda, A.
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 6 Pages: 555-561
- DOI
  10.1016/j.febslet.2013.01.057
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112722, KAKENHI-PROJECT-24591920, KAKENHI-PROJECT-24700974, KAKENHI-PROJECT-25290072, KAKENHI-PROJECT-25640081
[Journal Article] Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: potential unusual mechanism identifies G-rich introns2012
- Author(s)
  Sasaki-Haraguchi N, Shimada MK, Taniguchi I, Ohno M, Mayeda A
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 423 Pages: 289-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510271
[Journal Article] Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites.2012
- Author(s)
  Kameyama, T., Suzuki, H., Mayeda, A.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 40 Issue: 16 Pages: 7896-7906
- DOI
  10.1093/nar/gks520
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112722
[Journal Article] Mechanistic insights into human pre-mRNA splicing of human ultra-short introns : potential unusual mechanism identifies G-rich introns2012
- Author(s)
  Sasaki-Haraguchi N, Shimada MK, Taniguchi I, Ohno M, Mayeda A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510205
[Journal Article] スプライシング異常から解析する統合失調症2011
- Author(s)
  眞部孝幸、前田明
- Journal Title
  
  臨床検査
  
  Volume: 55 Pages: 893-899
- Data Source
  KAKENHI-PROJECT-24310161
[Journal Article] HMGA1a trapping of U1 snRNP at an authentic 5' splice site induces aberrant exon skipping in sporadic Alzheimer's disease2010
- Author(s)
  大江賢治, 前田明
- Journal Title
  
  Molecular and Cellular Biology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591679
[Journal Article] MGA1a trapping of U1 snRNP at an authentic 5' splice site induces aberrant exon skipping in sporadic Alzheimer's disease2010
- Author(s)
  Ohe K, Mayeda A
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 30 Pages: 2220-2228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591679
[Journal Article] The expression of HMGA1a is increased in lymphoblastoid cell lines from schizophrenia patients2010
- Author(s)
  Morikawa T, Manabe T, Ito Y, Yamada S, Yoshimi A, Nagai T, Ozaki N, Mayeda A
- Journal Title
  
  Neurochem Int
  
  Volume: 56(6-7) Pages: 736-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591679
[Journal Article] HMGA1a trapping of U1 snRNP at an authentic 5' splice site induces aberrant exon skipping in sporadic Alzheimer's disease.2010
- Author(s)
  Ohe K, Mayeda A
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 30 Pages: 2220-2228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591679
[Journal Article] がん遺伝子産物HMGA1aがひき起こす孤発性アルツハイマー病の異常スプライシング2009
- Author(s)
  前田明, 眞部孝幸, 大江賢治
- Journal Title
  
  蛋白質核酸酵素 54(12月増刊号)
  
  Pages: 2245-2250
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] RNPS1 in PSAP complex controls periodic pre-mRNA splicing over the cell cycle.2024
- Author(s)
  K. Fukumura, A. Masuda, J.-i. Takeda, K. Ohno, A. Mayeda
- Organizer
  The 29th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] エクソン接合部複合体(EJC)から形成されるmRNP密集構造はエキシトロン(エクソン内イントロン)で起こる異常スプライシングを抑制している.2023
- Author(s)
  藤田賢一, 大谷勇太, 亀山俊樹, P. Venhuizen, M. Kalyna, 前田明
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] Identified RBM17 (SPF45)-SAP30BP interaction promotes non-canonical splicing in a subset of human short introns.2023
- Author(s)
  K. Fukumura, L. Sperotto, Stefanie Seuss, H-S. Kang, R. Yoshimoto, M. Sattler, A. Mayeda
- Organizer
  The 28th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] Splicing in a subset of human short introns is promoted by SAP30BP-RBM17 but not by canonical U2AF2-UFAF1.2023
- Author(s)
  K. Fukumura, L. Sperotto, S. Seuss, H.-S. Kang, R. Yoshimoto, M. Sattler, A. Mayeda
- Organizer
  The 24th Annual Meeting of the RNA Society of Japan
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] SAP30BP-RBM17 interaction is an essential process to splice out a subset of human short introns.2023
- Author(s)
  福村和宏, L. Sperotto, S. Seuss, H.-S. Kang, 芳本玲, M. Sattler, 前田明
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] EJC core-triggered compacted mRNP structure represses cancer-specific splicing in exitron.2023
- Author(s)
  K.-I. Fujita, Y. Otani, T. Kameyama, P. Venhuizen, M. Kalyna, A. Mayeda
- Organizer
  Eukaryotic mRNA Processing Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] A novel pre-mRNA splicing mechanism with RBM17 (SPF45)-SAP30BP complex for a subset of human short introns.2022
- Author(s)
  K. Fukumura, L. Sperotto, H-S. Kang, Stefanie Seuss, R. Yoshimoto, M. Sattler, A. Mayeda
- Organizer
  Cold Spring Harbor Asia Conference: RNA Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] 45 years of splicing, 40 years of my studies, leading to the recent discovery of new splicing.2022
- Author(s)
  A. Mayeda
- Organizer
  Tokyo RNA Club:The 31st Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] The exon junction complex core represses cancer-specific mature mRNA re-splicing: A potential key role in terminating splicing.2021
- Author(s)
  Y. Ohtani, T. Kameyama, A. Mayeda
- Organizer
  The 26th Annual Meeting of the RNA Society (online meeting).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024
[Presentation] Repressors of cancer-specific mRNA re-splicing: Key factors for splicing fidelity or mRNA quality control?2019
- Author(s)
  A. Mayeda
- Organizer
  Annual Congress of Taiwan Society of Otorhinolaryngology Head and Neck Surgery/Taiwan Academy of Otology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] EJC represses caner-specific mature mRNA re-splicing: EJC as a guardian to maintain the integrity of mRNA2019
- Author(s)
  A. Mayeda
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] A distinct subset of human short introns with weak pyrimidine tract: U2AF heterodimer is replaced by SPF45/RBM17 as general splicing factor2019
- Author(s)
  A. Mayeda
- Organizer
  The 24th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] The PSAP complex is a global guardian of pre-mRNA splicing fidelity.2018
- Author(s)
  K. Fukumura, A. Mayeda
- Organizer
  Gordon Research Conference: Post-Transcriptional Gene Regulation--Integrating Technology and Mechanisms to Illuminate Function in RNA Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] EJCががん細胞特異的な成熟ｍRNA再スプライシングを抑制する: スプライシング正常化に働く新たなEJCの役割.2018
- Author(s)
  大谷雄太, 亀山俊樹, 前田明
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] A repressor candidate of cancer specific mRNA re-splicing: A key factor for splicing fidelity or mRNA quality control?2017
- Author(s)
  T. Kameyama, K. Fukumura, K. Inoue, T. Hirose, A. Mayeda
- Organizer
  2017 International Symposium on the 'Hallmarks of Cancer: Focus on RNA'
- Place of Presentation
  Prague Congress Center　(Czech Republic)
- Year and Date
  2017-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] A repressor candidate of cancer specific mRNA re-splicing: a key factor for splicing fidelity or mRNA quality control2017
- Author(s)
  T. Kameyama, K. Fumura, K. Inoue, T. Hirose, A. Mayeda
- Organizer
  International Symposium on the Hallmarks of Cancer: Focus on RNA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] A repressor candidate of cancer specific mRNA re-splicing: a key factor for splicing fidelity or mRNA quality control2017
- Author(s)
  T. Kameyama, K. Fumura, K. Inoue, T. Hirose, A. Mayeda
- Organizer
  The 22th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] がん抑制因子RBM4aはがん細胞特異的成熟ｍRNA再スプライシングを抑制する: ｍRNA品質保証の鍵となる因子か？2017
- Author(s)
  亀山俊樹, 福村和宏, 井上邦夫, 廣瀬哲朗, 前田明
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] A repressor candidate of cancer specific mRNA re-splicing: A key factor for splicing fidelity or mRNA quality control?2017
- Author(s)
  T. Kameyama, K. Fukumura, K. Inoue, T. Hirose, A. Mayeda
- Organizer
  The 22nd Annual Meeting of the RNA Society
- Place of Presentation
  Prague Congress Center (Czech Republic)
- Year and Date
  2017-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] 逆位スプライシングによって作られる環状RNAが核外に輸送される仕組み2017
- Author(s)
  芳本玲, 谷口一郎, 大野睦人, 前田明
- Organizer
  2017年度生命科学系学会合同年次大会（第４０回日本分子生物学会年会）
- Data Source
  KAKENHI-PROJECT-16K14659
[Presentation] 環状RNA（circRNA）の核外輸送機構の解明2017
- Author(s)
  芳本玲, 谷口一郎, 大野睦人, 前田明
- Organizer
  2017年度生命科学系学会合同年次大会（第４０回日本分子生物学会年会）
- Data Source
  KAKENHI-PROJECT-16K14659
[Presentation] Topological constraint and solution to generate circular RNA (circRNA) from linear RNA (pre-mRNA)2016
- Author(s)
  Mayeda A
- Organizer
  NAIST International Workshop "New era of pre-mRNA splicing world".
- Place of Presentation
  Nara Institute of Science and Technology, Nara, Japan.
- Year and Date
  2016-03-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310161
[Presentation] Topological constraint and solution to generate circular RNA (circRNA) from linear RNA (pre-mRNA).2016
- Author(s)
  Mayeda A
- Organizer
  NAIST International Workshop "New era of pre-mRNA splicing world".
- Place of Presentation
  Nara Institute of Science and Technology, Nara, Japan.
- Year and Date
  2016-03-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] Cisplatin-stimulated cancer-specific mature mRNA re-splicing is under the control of tumor suppressor p532016
- Author(s)
  T. Kameyama, Y. Amemoto, A. Mayeda
- Organizer
  The 21st Annual Meeting of the RNA Society / The 18th Annual Meeting of the RNA Society of Japan
- Place of Presentation
  京都国際会館（京都府、京都市）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] ヒト遺伝子の「無意味」な配列の「意味」を考えてみよう！2016
- Author(s)
  亀山俊樹, 芳本玲, 福村和宏, 嶋田誠, Maria Kalyna, 前田明
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H04705
[Presentation] Pre-mRNA splicing generates not only linear conding RNA (mRNA), but also circular non-coding RNA (circRNA)2016
- Author(s)
  A. Mayeda
- Organizer
  Mini-Symposium on ncRNA
- Place of Presentation
  Academia Sinica (Taipei, Taiwan)
- Year and Date
  2016-09-29
- Invited
- Data Source
  KAKENHI-PROJECT-16K14659
[Presentation] The functional circular RNA, ciRS-7/CDR1as, is biosynthesized from back-splicing promoted by Inverted MIR (not Alu) Elements.2016
- Author(s)
  R. Yoshimoto, T.B. Hansen, J. Kjems, A. Mayeda
- Organizer
  The 21th Annual Meeting of the RNA Society / The 18th Annual Meeting of the RNA Society of Japan
- Place of Presentation
  京都国際会館（京都府、京都市）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14659
[Presentation] Ultra-short G-rich introns with completely inefficient 5' and 3' splice sites are spliced in vivo, but how?2015
- Author(s)
  Mayeda A
- Organizer
  Eukaryotic mRNA Processing Meeting
- Place of Presentation
  Cold Spring Harbor Laboratory, New York, U.S.A.
- Year and Date
  2015-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310161
[Presentation] Ultra-short G-rich introns with completely inefficient 5' and 3' splice sites are spliced in vivo, but how?2015
- Author(s)
  Mayeda A
- Organizer
  Eukaryotic mRNA Processing Meeting
- Place of Presentation
  Cold Spring Harbor Laboratory, New York, U.S.A.
- Year and Date
  2015-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] Ultra-short G-rich introns with completely inefficient 5’ and 3’ splice sites are spliced in vivo, but how?2015
- Author(s)
  Shimada MK, Sasaki-Haraguchi N, Mayeda A
- Organizer
  Cold Spring Harbor Laboratory Meeting “Eukaryotic mRNA processing”
- Place of Presentation
  Cold Spring Harbor, NY.
- Year and Date
  2015-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24510271
[Presentation] Novel mRNA Re-splicing Event as Potential Paradigm for Understanding Robustness and Catastrophe in Gene Expression Systems2014
- Author(s)
  Toshiki Kameyama, Ryoichi Shiroki, Nobuhiko Emi, Akila Mayeda
- Organizer
  The 2nd International Symposium on Dynamical Ordering of Biomolecular Systems for Creation of Integrated Functions
- Place of Presentation
  キャンパスプラザ、京都
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] 癌細胞における成熟mRNAの異常再スプライシングの発見と意義2014
- Author(s)
  亀山俊樹、前田明
- Organizer
  平成25年度「個体レベルでのがん研究支援活動」ワークショップ: 個体レベルから見た炎症と癌
- Place of Presentation
  琵琶湖ホテル、滋賀
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] Novel mRNA re-splicing event: Important aspects for understanding robustness and catastrophe in gene expression systems.2014
- Author(s)
  A. Mayeda
- Organizer
  RIKEN Symposium and 15th Tokyo RNA Club
- Place of Presentation
  理化学研究所、和光市
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-24310161
[Presentation] Novel mRNA re-splicing event: Important aspects for understanding robustness and catastrophe in gene expression systems2014
- Author(s)
  A. Mayeda
- Organizer
  RIKEN Syposium and 15th Tokyo RNA Club
- Place of Presentation
  理化学研究所、和光市
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] Sequence-specific RNA-binding of HMGA1a may play a role in acquired resistance of estrogen receptor-positive breast carcinoma2013
- Author(s)
  Ohe K, Miyajima S, Kuwasako K, Muto Y, Utsumi T, Hagiwara M, Mayeda A
- Organizer
  Eukaryotic mRNA Processing Meeting
- Place of Presentation
  Cold Spring Harbor Laboratory, USA
- Data Source
  KAKENHI-PROJECT-24310161
[Presentation] DMD遺伝子のホットスポットのスキップ産物とcircRNA2013
- Author(s)
  鈴木仁、亀山俊樹、前田明、塚原俊文
- Organizer
  第15回日本RNA学会年会
- Place of Presentation
  愛媛県民文化会館・ひめぎんホール、愛媛
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] Mature mRNA Resplicing in Cancer Cells Postulates Undiscovered Quality Control Mechanism of mRNA in Normal Cells2013
- Author(s)
  Toshiki Kameyama, Akila Mayeda
- Organizer
  BRI International Symposium　2013: RNA World in Brain
- Place of Presentation
  新潟大学脳研究所、新潟
- Invited
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] Sequence-specific RNA-binding of HMGA1a may play a role in acquired resistance of estrogen receptor-positive breast carcinoma2013
- Author(s)
  Kenji Ohe, Shinsuke Miyajima, Kanako Kuwasako, Yutaka Muto, Toshiaki Utsumi, Masatoshi Hagiwara, Akila Mayeda
- Organizer
  2013 CSHL Meeting on Eukaryotic mRNA Processing
- Place of Presentation
  コールドスプリングハーバー、ニューヨーク、米国
- Data Source
  KAKENHI-PROJECT-24591920
[Presentation] Splicing of Alzheimer's disease: Discovery, mechanism of action, therapeutic insights, and biological significance2013
- Author(s)
  前田明
- Organizer
  BRI International Conference: RNA World in Brain
- Place of Presentation
  新潟大学脳研究所、新潟
- Invited
- Data Source
  KAKENHI-PROJECT-24310161
[Presentation] Analysis of the intron distribution of the human genes implicates the existence of ultra-short introns（ヒト遺伝子のイントロン長分析から明らかになった微小イントロンの存在）2012
- Author(s)
  嶋田　誠、佐々木（原口）典子、前田　明
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24510271
[Presentation] Mature mRNA resplicing in cancer cells postulates undiscovered quality control mechanism of mRNA in normal cells2012
- Author(s)
  Kameyama, T., Mayeda, A.
- Organizer
  The 22nd CDB Meeting: RNA Sciences in Cell and Developmental Biology II
- Place of Presentation
  Kobe, Japan
- Year and Date
  2012-06-11
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] 外れ値にあたる短さをもつヒト・イントロンの進化的保存性2012
- Author(s)
  嶋田　誠、佐々木（原口）典子、前田　明
- Organizer
  日本霊長類学会第28回学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24510271
[Presentation] ヒトにおける規格外に短いイントロンの発見とその特徴2012
- Author(s)
  嶋田　誠、佐々木（原口）典子、前田　明
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24510271
[Presentation] 乳癌における癌遺伝子産物HMGA1aによるERα46 の発現調節機構2012
- Author(s)
  宮島慎介、大江賢治、牛窓かおり、引地理浩、小林尚美、前田明、内海俊明
- Organizer
  第20回　日本乳癌学会学術総会
- Place of Presentation
  熊本市民会館
- Data Source
  KAKENHI-PROJECT-24591920
[Presentation] Mature mRNA resplicing in cancer cells postulates undiscovered quality control mechanism of mRNA in normal cells2012
- Author(s)
  Kameyama, T., Mayeda, A.
- Organizer
  Gordon Research Conference: The Biology of Post-Transcriptional Gene Regulation
- Place of Presentation
  Newport, U.S.A.
- Year and Date
  2012-07-15
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] がん細胞で発見された成熟mRNA再スプライシングから正常細胞で重要なmRNA品質管理機構が想定できる2012
- Author(s)
  亀山俊樹、前田明
- Organizer
  第35回　分子生物学会年会：　ワークショップ「 RNA病解明への挑戦」
- Place of Presentation
  福岡、日本
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] Characterization of Evolutionary Conserved Unusually Short Human Introns2011
- Author(s)
  Shimada MK, Sasaki-Haraguchi N, Mayeda A
- Organizer
  Annual Meeting of the Society for Molecular Biology and Evolution(SMBE2011)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] A Novel Sequence Signal That Promotes Pre-mRNA Splicing without U1 snRNP2011
- Author(s)
  Kenji Ohe, Eiji Sakashita, Hitoshi Endo, Akila Mayeda
- Organizer
  第16回RNA society国際会議
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] Characterization of Evolutionary Conserved Unusually Short Human Introns2011
- Author(s)
  Shimada MK, Sasaki-Haraguchi N, Mayeda A
- Organizer
  Annual Meeting of the Society for Molecular Biology and Evolution (SMBE2011)
- Place of Presentation
  京都国際会議場(京都)
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Identification and Characterization of Unusually Small Introns, Termed Micro-introns, in the Human Genomes2011
- Author(s)
  Shimada MK, Sasaki-Haraguchi N, Mayeda A
- Organizer
  The 16^<th> Annual Meeting of the RNA Society and The RNA Society of Japan 13^<th> Annual Meeting
- Place of Presentation
  京都大学(京都)
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Resplicing of mature mRNA in cancer cells : two-step splicing mechanism to activate far distant alternative splice sites2011
- Author(s)
  T.Kameyama, A.Mayeda
- Organizer
  Eukaryotic RNA Processing Meeting
- Place of Presentation
  Cold Spring Harbor Laboratory, New York, U.S.A.
- Year and Date
  2011-08-25
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] Identification and Characterization of Unusually Small Introns, Termed Micro-introns, in the Human Genomes2011
- Author(s)
  Shimada MK, Sasaki-Haraguchi N, Mayeda A
- Organizer
  The 16th Annual Meeting of the RNA Society and The RNA Society of Japan 13th Annual Meeting
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Aberrant re-splicing of mature spliced mRNA discovered in cancer cells : Considering its generality and significance2011
- Author(s)
  T.Kameyama, A.Mayeda
- Organizer
  The 16^<th> annual meeting of the RNA society
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2011-06-14
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] HMGA1に対する「おとり」RNAは、エストロゲン受容体αの異常スプライシングを是正する2010
- Author(s)
  大江賢治、内海俊明、前田明
- Organizer
  第18回日本ステロイドホルモン学会年会
- Place of Presentation
  名古屋市、WINC AICHI
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] HMGA1a induces aberrant splicing of Estrogen Receptor α in MCF-7 breast cancer cells2010
- Author(s)
  Kenji Ohe, Toshiaki Utsumi, Akila Mayeda
- Organizer
  第6回国際ホルモン依存性癌シンポジウム
- Place of Presentation
  シエラトン・グランデ・トーキョーベイ・ホテル
- Year and Date
  2010-09-12
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] Evolution of spliceosomal proteins : High conservation and low modification, but drastic change in parasitic genome.2010
- Author(s)
  嶋田誠、内山郁夫、前田明
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] RNAスプライシング機構の進化:スプライシング因子保存性についての網羅的解析2010
- Author(s)
  嶋田誠、内山郁夫、前田明
- Organizer
  第12回日本進化学会大会
- Place of Presentation
  東京工業大(東京都)
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Aberrant splicing by an activation of the 5' and 3' cryptic Splice sites in the far distant exons takes place after thenormal constitutive splicing2010
- Author(s)
  T.Kameyama, A.Mayeda
- Organizer
  Gordon Research Conference : The biology of post-transcriptional gene regulation
- Place of Presentation
  Salve Regina University, U.S.A.(招待講演)
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-20651051
[Presentation] HMGA1a induces aberrant splicing of Estrogen Receptor α in MCF-7 breast cancer cells2010
- Author(s)
  大江賢治, 内海俊明, 前田明
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  京都市、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] HMGA1に対する「おとり」RNAは、エストロゲン受容体αの異常スプライシングを是正する2010
- Author(s)
  江賢治、内海俊明、前田明
- Organizer
  第18回日本ステロイドホルモン学会年会
- Place of Presentation
  名古屋市
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] ヒト免疫不全ウイルス特異的なスプライシングに必要な新しい宿主因子の解析2010
- Author(s)
  大江賢治、鶴野親是、倉光球、高浜洋一、浜口功、大隈和、前田明
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京、学術総合センター一ツ橋記念講堂
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] Human transcript database search showed existence of extremely short introns.2010
- Author(s)
  Shimada MK, Haraguchi N, Mayeda A
- Organizer
  The Conference of the International Society for Biocuration
- Place of Presentation
  Odaiba, Tokyo
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Different mechanisms to splice micro-introns in Eukaryotes2010
- Author(s)
  Shimada MK, Uchiyama I, Mayeda A
- Organizer
  Annual Meeting of the Society for Molecular Biology and Evolution(SMBE2010)
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] ヒト免疫不全ウイルス特異的なスプライシングに必要な新しい宿主因子の解析2010
- Author(s)
  大江賢治、鶴野親是、倉光球、高浜洋一、浜口功、大隈和、前田明
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京、学術総合センター、一ツ橋記念講堂
- Year and Date
  2010-07-27
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] Human transcript database search showed existence of extremely short introns2010
- Author(s)
  Shimada MK, Haraguchi N, Mayeda A
- Organizer
  The Conference of the International Society for Biocuration(Biocuration 2010)
- URL
  http://dx.doi.org/10.1038/npre.2010.5115.1
- Place of Presentation
  Odaiba, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] HMGA1a induces aberrant splicing of Estrogen Receptor α in MCF-7 breast cancer cells2010
- Author(s)
  Kenji Ohe, Toshiaki Utsumi, kila Mayeda
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  京都市、国立京都国際会館
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] 癌細胞で発見した成熟mRNAの異常スプライシング現象の普遍性と重要性2010
- Author(s)
  亀山俊樹、前田明
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20651051
[Presentation] RNAスプライシング機構の進化:スプライシング因子保存性についての網羅的解析2010
- Author(s)
  嶋田誠、内山郁夫、前田明
- Organizer
  第12回日本進化学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] HMGA1a induces aberrant splicing of Estrogen Receptor α in MCF-7 breast cancer cells2010
- Author(s)
  Kenji Ohe, Toshiaki Utsumi, Akila Mayeda
- Organizer
  第6回国際ホルモン依存性癌シンポジウム
- Place of Presentation
  千葉、シエラトン・グランデ・トーキョーベイ・ホテル
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] Different mechanisms to splice micro-introns in Eukaryotes.2010
- Author(s)
  Shimada MK, Uchiyama I, Mayeda A
- Organizer
  Annual Meeting of the Society for Molecular Biology and Evolution
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Evolution of spliceosomal proteins : High conservation and low modification, but drastic change in parasitic genome(スプライソソーム・タンパク質の進化:高保存・低変更なシステム、ただし寄生性ゲノムにおける劇的な変更)2010
- Author(s)
  嶋田誠、内山郁夫、前田明
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] 成熟mRNAの異常再スプライシング現象:癌細胞で破綻しているスプライシングの終了機構は何だろう?2009
- Author(s)
  亀山俊樹, 前田明
- Organizer
  第11回日本RNA学会年
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-20651051
[Presentation] Widely Distributed Pre-mRNA Micro-Introns in the Human Genome : Are They Spliced in the Conventional Pathways2009
- Author(s)
  原口典子、嶋田誠、前田明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Aberrant re-splicing of mature mRNA : What is splicing termination mechanism hidden2009
- Author(s)
  亀山俊樹, 前田明
- Organizer
  The 2009 Meeting on Eukaryotic mRNA Processing
- Place of Presentation
  Cold Spring Harbor Laboratory, U.S.A.
- Year and Date
  2009-08-19
- Data Source
  KAKENHI-PROJECT-20651051
[Presentation] 癌遺伝子産物HMGA1が、乳癌においてエストロゲン受容体αの異常スプライシングの誘導因子として機能しているかもしれない!2009
- Author(s)
  大江賢治, 内海俊明, 前田明
- Organizer
  第11回日本RNA学会年会
- Place of Presentation
  新潟市、朱鷺メッセ
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] 標準的なスプライシング複合体で遂行されるスプライシング反応系の中に新たな分子機構が存在する可能性を探る2009
- Author(s)
  嶋田誠、前田明
- Organizer
  第11回日本進化学会大会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] イントロン長の集計によるスプライシング機構多様性の推定2009
- Author(s)
  嶋田誠、原口典子、前田明
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] Aberrant re-splicing of mature mRNA : What is splicing termination mechanism hidden2009
- Author(s)
  亀山俊樹, 前田明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20651051
[Presentation] 癌遺伝子産物HMGA1が、乳癌においてエストロゲン受容体αの異常スプライシングの誘導因子として機能しているかもしれない!2009
- Author(s)
  大江賢治、内海俊明、前田明
- Organizer
  第11回日本RNA学会年会
- Place of Presentation
  新潟市
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] Oncogenic Product HMGA1a Might Function as Aberrant Splicing Inducer of Estrogen Receptor α in Breast Cancer2009
- Author(s)
  Kenji Ohe, Toshiaki Utsumi, Akila Mayeda
- Organizer
  2009 EUKARYOTIC mRNA PROCESSING meeting(Cold Spring Harbor Laboratory meeting)
- Place of Presentation
  ニューヨーク州、コールド・スプリング・ハーバー
- Year and Date
  2009-08-18
- Data Source
  KAKENHI-PROJECT-21591679
[Presentation] Are Spliceosomal Proteins Required to Splice Extremely Small Introns, termed Micro-introns, in non-metazoa?(非後生動物の極端に短いイントロン(極小イントロン)でもスプライセオソームタンパク質が使われているのか?)2009
- Author(s)
  嶋田誠、前田明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21510205
[Presentation] がん細胞で発見された成熟mRNA再スプライシングから正常細胞で重要なmRNA品質管理機構が想定できる。
- Author(s)
  亀山俊樹、前田明
- Organizer
  第35回分子生物学会年会 : ワークショップ「RNA病解明への挑戦」
- Place of Presentation
  福岡、日本
- Year and Date
  2012-12-11 – 2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] Mature mRNA resplicing in cancer cells postulates undiscovered quality control mechanism of mRNA in normal cells.
- Author(s)
  Kameyama, T., Mayeda, A.
- Organizer
  The 22^<nd> CDB Meeting : RNA Sciences in Cell and Developmental Biology ll
- Place of Presentation
  Kobe, Japan
- Year and Date
  2012-06-11 – 2012-06-13
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] Mature mRNA resplicing in cancer cells postulates undiscovered quality control mechanism of mRNA in normal cells.
- Author(s)
  Kameyama, T., Mayeda, A.
- Organizer
  Gordon Research Conference : The Biology of Post-Transcriptional Gene Regulation
- Place of Presentation
  Newport, U.S.A.
- Year and Date
  2012-07-15 – 2012-07-20
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] mRNA前駆体スプライシング研究の最前線：異常スプライシングから見えてくる疾患の原因と治療
- Author(s)
  前田明
- Organizer
  東海血液疾患フォーラム（特別講演）
- Place of Presentation
  ヒルトンホテル、名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-25640081
[Presentation] mRNA前駆体スプライシング研究の最前線：異常スプライシングから見えてくる疾患の原因と治療
- Author(s)
  前田明
- Organizer
  東海血液疾患フォーラム
- Place of Presentation
  ヒルトンホテル、名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24310161
[Presentation] Aberrant re-splicing of mature spliced mRNA discovered in cancer cells : Considering its generality and significance.
- Author(s)
  Kameyama, T., Mayeda, A.
- Organizer
  The 16^<th> annual meeting of the RNA society
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-07-14 – 2011-07-18
- Data Source
  KAKENHI-PUBLICLY-23112722
[Presentation] ヒト微小イントロンは4 種類の進化様式で出現した
- Author(s)
  (27)嶋田　誠、佐々木（原口）典子、前田　明
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウィンクあいち（愛知県名古屋市）
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-24510271
[Presentation] Resplicing of mature mRNA in cancer cells : Two-step splicing Mechanism to activate far distant alternative splice sites.
- Author(s)
  Kameyama, T., Mayeda, A.
- Organizer
  Eukaryotic RNA Processing Meeting
- Place of Presentation
  Cold Spring Harbor, U.S.A.
- Year and Date
  2011-08-23 – 2011-08-27
- Data Source
  KAKENHI-PUBLICLY-23112722

1. OHE Kenji (30419527)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
2. UTSUMI Toshiaki (10176711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. SHIROKI Ryoichi (70226330)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. SASAKI Noriko (90546649)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
5. SHIMADA Makoto (00528044)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
6. KATAYAMA Tai-ichi (80333459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MUTOH Yutaka (30192769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. NAMEKI Kanako (10568736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAMEYAMA Toshiki (60298544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. SUGIOKA Atsushi (20171150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YOSHIMOTO Rei (70595652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
12. OHNO Mutsuhito (80201979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 藤井多久磨 (10218969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 恵美宣彦 (30185144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 住友誠 (50255535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高原健 (90418939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 全並賢二 (60440731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 福村和宏 (80622117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MIKAKO Ito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. SUZUKI Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 桑迫香奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 中川真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 塚原俊文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 武田伸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mayeda Akila 前田 明

MAYEDA Akila 前田 明

Research Projects

Research Products

Co-Researchers

The discovery of new essential splicing factors restructure a set of human intronsPrincipal Investigator

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Understanding the mechanism underlying splicing termination with mRNA re-splicing repressorPrincipal Investigator

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鏡視下膀胱全摘除術後の特異的腫瘍再発に関連する腫瘍細胞の生化学的解析と術式の検討

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Exploring the implications of cancer-specific mRNA re-splicing events in the robustness and catastrophe of gene expression systemPrincipal Investigator

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Mechanisms to make important noncoding RNAs from dispensable coding RNAsPrincipal Investigator

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Search for the cause of proteomic disorder without genomic mutations in the global mis-regulation of splicingPrincipal Investigator

Principal Investigator

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Global disorder of splicing caused by oncogene product HMGA1Principal Investigator

Principal Investigator

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Exploring a novel therapy of hormone-resistant breast cancer by short RNA

Principal Investigator

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Bioinformatic and molecular biological study on ultra-short introns

Principal Investigator

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ｍＲＮＡの再スプライシング現象から探る未知のｍＲＮＡ品質管理機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bioinformatic and molecular biological study on ultra-short introns

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Estrogen Receptor Alpha through novel function of HMGA1a.-Towards a novel breast cancer therapy-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトゲノムに散在する巨大遺伝子の発現機構:イントロン内スプライシング予想の証明Principal Investigator

Principal Investigator

Project Period (FY)

Mayeda Akila 前田明

MAYEDA Akila 前田明