YOSHIZAWA Toshihiro 吉澤利弘

… Alternative Names

吉沢利弘ヨシザワトシヒロ

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Researcher Number	50212311
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: 筑波大, 人間総合科学研究科, 講師 2004 – 2005: University of Tsukuba, Graduate School of Comprehensive Human Science, Assistant Professor, 大学院・人間総合科学研究科, 講師 2003: 筑波大学, 臨床医学系, 講師 1998 – 2001: 筑波大学, 臨床医学系, 講師 1999: Tsukuba Univ. Med. School, Department of Neurology, lecturer, 臨床医学系・神経内科, 講師 1998 – 1999: 筑波大学, 臨床医学系神経内科, 講師 1991 – 1993: 筑波大学, 臨床医学系, 講師
Review Section/Research Field	Principal Investigator Neurology / Neurology / Biological Sciences Except Principal Investigator Cell biology / Neurology
Keywords	Principal Investigator ataxin-3 / マシャド・ジョセフ病 / ポリグルタミン病 / 細胞死 / aggregation / cell death / neuron / polyglutamine / Machado-Joseph disease / 凝集体 … More / Machado-Joseph病 / 凝集体形成 / ectoine / Machado-Joseph Disease / polyglutamine disease / マシャド・ジョセア病 / エクトイン / polyclonal antibody / 抗体 / ポリクローナル抗体 / cell cycle / ポリグルタシ鎖 / トソプレット病 / 細胞周期 / 神経細胞死 / P19細胞 … More Except Principal Investigator Bcl-2 / Cu / immunosuppressants / neuron / cancer / ischemia / apoptosis / calcineurin / phosphorylation / glia / Transgenic / 細胞死 / NF-AT / 虚血 / リン酸化 / 転写因子 / アポトーシス / 免疫系 / 神経系 / カルシニューリン / oxidative stress / Zu SOD / ferric iron / alphaB-cystallin / ubiquitin / oligodendroglia / argyrophilic inclusion / Multiple system atrophy / ZnSOD / 3価鉄 / αBクリスタル / 酸化ストレス / Zn SOD / 三価鉄 / αBクリスタリン / ユビキチン / オリゴデンドログリア / 嗜銀性封入体 / 多系統変性症 Less

マシャド・ジョセフ病遺伝子産物の結合タンパク解析による分子病態解明の研究Principal Investigator
- Principal Investigator
  
  吉澤利弘
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  University of Tsukuba
Evaluation of suppressive effects of drugs on cell death using cellular and transgenic models of polyglulamine disease.Principal Investigator
- Principal Investigator
  
  YOSHIZAWA Toshihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  University of Tsukuba
マシャド・ジョセフ病における神経細胞死選択性の基礎研究Principal Investigator
- Principal Investigator
  
  吉澤利弘
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
INVESTIGATION OF DIFFERENTIAL SUSCEPTIBILITY TO CELL DEATH IN POLYGLUTAMINE DISEASESPrincipal Investigator
- Principal Investigator
  
  YOSHIZAWA Toshihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  UNIVERSITY OF TSUKUBA
Role of calcineurin in neurons and immune cells
- Principal Investigator
  
  SHINBASAKI Futoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
IN VITRO CELLULAR MODEL FOR MACHADO-JOSEPH DESEASE, A MODEL FOR TRIPLET REPEAT DISEASES.Principal Investigator
- Principal Investigator
  
  YOSHIZAWA Toshihiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  University of Tsukuba
A morphological and biochemical study of argyrophilic inclusions in multiple system atrophy
- Principal Investigator
  
  MIZUSAWA Hidehiro
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  University of Tsukuba

All 2006 2005 2004 2003 Other

All Journal Article

[Journal Article] A novel GRPase, CRAG, mediates PML-associated nuclear body formation and degradation of expanded polyglutamine protein2006
- Author(s)
  Qin Q, Inatome R, Hotta A, Kijima M, Yamamura H, Hirai H, Yoshizawa T, Tanaka H, Fukami K, Yanagi S
- Journal Title
  
  J Cell Biol (in press)
- Data Source
  KAKENHI-PROJECT-17590858
[Journal Article] ANCA-associated vasculitis (AAV) causing bilateral cerebral infarction and subsequent intracerebral hemorrhage without renal and respiratory dysfunction.2006
- Author(s)
  Ito Y, Suzuki K, Yamazaki T, Yoshizawa T, Ohkoshi N, Matsumura A
- Journal Title
  
  Journal of Neurological Sciences 240
  
  Pages: 99-101
- Data Source
  KAKENHI-PROJECT-17590858
[Journal Article] Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.2005
- Author(s)
  Furusho K, Yoshizawa T, Shoji S
- Journal Title
  
  Neurobiology of Disease (in press)
- Data Source
  KAKENHI-PROJECT-15590877
[Journal Article] Ectoine alters subcelluar localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.2005
- Author(s)
  Furusho K, Yoshizawa T, Shoji S
- Journal Title
  
  Neurobiology of Disease 20
  
  Pages: 170-178
- Data Source
  KAKENHI-PROJECT-17590858
[Journal Article] MRIで髄内病変を明確に描出し得た長期経過のflexion myelopathy.2005
- Author(s)
  辻浩史, 吉澤利弘, 玉岡晃
- Journal Title
  
  神経内科 63
  
  Pages: 299-300
- Data Source
  KAKENHI-PROJECT-17590858
[Journal Article] MRミエログラフィーが漏出部位推定に有用であった特発性髄液圧症候群の1例2005
- Author(s)
  上野卓教, 吉澤利弘, 町野毅, 庄司進一, 阿武泉
- Journal Title
  
  日本内科学会雑誌 94
  
  Pages: 2382-2384
- Data Source
  KAKENHI-PROJECT-17590858
[Journal Article] Choreaで発症し、抗VGKC抗体陽性を認めた膀腫瘍性神経症候群が疑われる1例2005
- Author(s)
  大越教夫, 石井亜紀子, 渡邊雅彦, 中馬越清隆, 望月昭英, 吉澤利弘, 庄司進一
- Journal Title
  
  運動障害 13
  
  Pages: 23-26
- Data Source
  KAKENHI-PROJECT-17590858
[Journal Article] Early vestibular dysfunction in Machado-Joseph disease detected by caloric test.2004
- Author(s)
  Yoshizawa T, Nakamagoe K, Ueno T, Furusho K, Shoji S
- Journal Title
  
  Journal of Neurological Sciences 221
  
  Pages: 109-111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590877
[Journal Article] Early vestibular dysfunction in Machado-Joseph disease detected by caloric test.2004
- Author(s)
  Yoshizawa T.Nakamagoe K, Ueno T, Furusho K, Shoji S
- Journal Title
  
  Journal of Neurological Sciences 221
  
  Pages: 109-111
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590877
[Journal Article] Magnetic resonance imaging demonstrates differential atrophy of pontine base and tegmentum in Machado-Joseph disease.2003
- Author(s)
  Yoshizawa T, Watanabe M, Furusho K, Shoji S
- Journal Title
  
  Journal of Neurological Sciences 215
  
  Pages: 45-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590877
[Journal Article] Ectoine alters subcelluar localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.
- Author(s)
  Furusho K, Yoshizawa T, Shoji S
- Journal Title
  
  Neurobiology of Disease (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590877
[Journal Article] Ectoine alters subcelluar localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.
- Author(s)
  Furusho K, Yoshizawa T, Shoji S
- Journal Title
  
  Neurobiology of Disease (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590877

1. MIZUSAWA Hidehiro (30144091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SHINBASAKI Futoshi (90300954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KONDO Eisaku (30252951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OMORI Nobuhiko (80311421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOSHIZAWA Toshihiro 吉澤 利弘

吉沢 利弘 ヨシザワ トシヒロ

Research Projects

Research Products

Co-Researchers

マシャド・ジョセフ病遺伝子産物の結合タンパク解析による分子病態解明の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of suppressive effects of drugs on cell death using cellular and transgenic models of polyglulamine disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マシャド・ジョセフ病における神経細胞死選択性の基礎研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

INVESTIGATION OF DIFFERENTIAL SUSCEPTIBILITY TO CELL DEATH IN POLYGLUTAMINE DISEASESPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of calcineurin in neurons and immune cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IN VITRO CELLULAR MODEL FOR MACHADO-JOSEPH DESEASE, A MODEL FOR TRIPLET REPEAT DISEASES.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A morphological and biochemical study of argyrophilic inclusions in multiple system atrophy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A novel GRPase, CRAG, mediates PML-associated nuclear body formation and degradation of expanded polyglutamine protein2006

Author(s)

Journal Title

Data Source

[Journal Article] ANCA-associated vasculitis (AAV) causing bilateral cerebral infarction and subsequent intracerebral hemorrhage without renal and respiratory dysfunction.2006

Author(s)

Journal Title

Data Source

[Journal Article] Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.2005

Author(s)

Journal Title

Data Source

[Journal Article] Ectoine alters subcelluar localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.2005

Author(s)

Journal Title

Data Source

[Journal Article] MRIで髄内病変を明確に描出し得た長期経過のflexion myelopathy.2005

Author(s)

Journal Title

Data Source

[Journal Article] MRミエログラフィーが漏出部位推定に有用であった特発性髄液圧症候群の1例2005

Author(s)

Journal Title

Data Source

[Journal Article] Choreaで発症し、抗VGKC抗体陽性を認めた膀腫瘍性神経症候群が疑われる1例2005

Author(s)

Journal Title

Data Source

[Journal Article] Early vestibular dysfunction in Machado-Joseph disease detected by caloric test.2004

Author(s)

Journal Title

Description

Data Source

YOSHIZAWA Toshihiro 吉澤利弘

吉沢利弘ヨシザワトシヒロ