TAKAHASHI Satoshi 高橋智

Researcher Number	50216719
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012: 岩手医科大学, 医学部, 教授 2011: 岩手医科大学, 医学部, 准教授 2005 – 2006: 岩手医科大学, 医学部, 助教授 1995 – 2002: 岩手医科大学, 医学部, 講師 1993: 岩手医科大学, 医学部, 講師 1991 – 1993: 岩手医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurology Except Principal Investigator Neurology / Radiation science / Applied entomology
Keywords	Principal Investigator CTG反復配列 / 海馬 / 白質病変 / 知能障害 / 筋強直性ジストロフィー / alpha-TQ / alpha-TOH / ビタミンE / 抗酸化物質 / 脳脊髄液 / ビンスワンガー型痴呆 / アルツハイマー型痴呆 … More Except Principal Investigator … More aging / 老化 / α7nAChR / PC12 / neurite outgrowth / human brain / extracellular-signal-regulated kinase / cell cycle / cDNA array / ニューロン / tau / APP / RAGE / transcription / promoter / methylcytosines / dopamine / GABA / Glutamate / Serotonin / Dopamine / Parkinson's disease / schizophrenia / depression / noradrenaline / locus ceruleus / substantia nigra / neuromelanin / magnetic resonance imaging / Parkinson病 / 統合失調症 / うつ病 / ドパミン / ノルアドレナリン / 青斑核 / 黒質 / 神経メラニン / MRI / リン酸化 / アセチルコリン受容体 / DNAアレイ / ERK / α7nAchR / 転写調節領域 / タウ蛋白 / アミロイド前駆体蛋白 / bisulfite法 / 加齢 / プロモーター領域 / メチルシトシン / 補体 / α7サブユニット / ニコチン性Ach受容体 / nicotinic acetyocholine receptor subunits(alpha4, beta2) / dopamine receptor (D_1, D_2) / nuclear receptors / molecular chaperone / selective vulnerability / neuron death / 海馬 / ニューロン死 / rt-PCR / D_1,S_2受容体 / 線条体 / ニコチン性アセチルコリン受容体 / 核内受容体 / D_1,D_2受容体 / ペプチド前駆物質 / 熱ショックタンパク / 選択的脆弱性 / 神経細胞死 / 3-O-methydopa / Norepinephrine / 3ーOーmthldopa / Lーdopa / tyrosine / cerebrospinal fluid / 5-HIAA / Serotonin(5-HT) / tryptophan / Kynurenine / 3-0-methydopa / Norepinophrine / 生理活性 / 養蚕 / 昆虫機能利用 / 昆虫バイオテクノロジー / 生物有機科学 / 脳神経疾患 / 脳神経 / 生物有機化学 / 病理解剖 / 養蚕イノベーション / 有用物質生産 / 機能開発 / 昆虫利用 Less

Structure and function of an improving factor in hippocampal impairment originated from the silkworm-parasitic fungus (Paecilomyces tenuipes) and practical use for human brain
- Principal Investigator
  
  Suzuki Koichi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied entomology
- Research Institution
  Iwate University
In vivo imaging of dopaminergic and noradrenergic neurons using neuromelanin-sensitive MRI
- Principal Investigator
  
  SASAKI Makoto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Iwate Medical University
Gene expression profile of aging human brain and its in vitro model
- Principal Investigator
  
  TOHGI Hideo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Iwate Medical University
Changes with age in DNA methylation and transcription in human cerebral cortex.
- Principal Investigator
  
  TOHGI Hideo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neurology
- Research Institution
  Iwate Medical University
筋緊張性ジストロフィー症の知能障害-遺伝子不安定領域、脳循環、海馬萎縮の検討-Principal Investigator
- Principal Investigator
  
  高橋智
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Iwate Medical University
Selective Vulnerability of neurons in age-related neuronal death and its molecular mechanisms
- Principal Investigator
  
  TOHGI Hideo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Department of Neurology, Iwate Medical University
老年期痴呆における髄液中抗酸化物質および神経伝達物質の変化とその病態生化学的意義Principal Investigator
- Principal Investigator
  
  高橋智
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Iwate Medical University
Alterations in concentrations of neurotransmitters in cerebrospinal fluid in patients with Parkinson's disease.
- Principal Investigator
  
  TOHGI Hideo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Iwata Medical University

All 2015 2014 2006 Other

All Journal Article Presentation

[Journal Article] 18F-AV45(Florbetapir F18)を用いた認知症における脳アミロイドイメージング2015
- Author(s)
  柴田俊秀・米澤久司・高橋純子・工藤雅子・小原智子・鈴木真紗子・石塚直樹・藤澤豊・佐々木敏秋・寺崎一典・世良耕一郎・寺山靖夫
- Journal Title
  
  脳循環代謝
  
  Volume: 26 Pages: 11-18
- NAID
  130005093691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23228001
[Journal Article] Detection of early changes in the parahippocampal and posterior cingulum bundles during mild cognitive impairment by using high-resolution multi-parametric diffusion tensor imaging2015
- Author(s)
  Ito, K., Sasaki, MM., Takahashi, J., Uwano, I., Yamashita, F., Higuchi, S., Goodwin, J., Harada, T., Kudo, K. and Terayama, Y.
- Journal Title
  
  Psychiatry Rresearch: Neuroimaging
  
  Volume: 231 Issue: 3 Pages: 346-352
- DOI
  10.1016/j.pscychresns.2015.01.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-25861119
[Journal Article] Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer's disease: High-resolution fast spin-echo T1weighted imaging2015
- Author(s)
  Takahashi, J., Shibata, T., Sasaki, M., Kudo, M., Yanezawa, H., Obara, S., Kudo, K., Ito, K., Yamashita, F. and Terayama, Y.
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 15 Issue: 3 Pages: 334-340
- DOI
  10.1111/ggi.12280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-25861119
[Journal Article] 18Ｆ-ＡＶ45（Ｆｌｏｒｂｅｔａｐｉｒ）を用いた脳アミロイドイメージング2014
- Author(s)
  工藤雅子・米澤久司・柴田俊秀・小原智子・高橋純子・佐々木敏秋・寺崎一典・世良耕一郎・寺山靖夫
- Journal Title
  
  脳循環代謝
  
  Volume: 25 Pages: 91-96
- NAID
  130004708209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23228001
[Journal Article] Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease2006
- Author(s)
  Sasaki M, Shibata E, Tohyama K, Takahashi J, Otsuka K, Tsuchiya K, Takahashi S, Ehara S, Terayama Y, Sakai A
- Journal Title
  
  Neuroreport 17(11)
  
  Pages: 1215-1218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591290
[Presentation] カイコ冬虫夏草に由来する海馬修復因子の精製と機能解析2015
- Author(s)
  石黒慎一・Piyamas Sillapakong・苅間澤真弓・江幡真規子・佐々木謙吾・高橋真奈美・漆畑拓弥・若林篤光・松浦哲也・品田哲郎・鈴木幸一
- Organizer
  平成27年度蚕糸・昆虫機能利用学術講演会（日本蚕糸学会第85回大会）
- Place of Presentation
  北海道大学農学部
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-23228001
[Presentation] Alzheimer病およびMCI患者における記憶機能検査(WMS-R)成績の検討2015
- Author(s)
  石塚直樹・鈴木真紗子・坂本暁恵・高橋純子・工藤雅子・米澤久司・寺山靖夫
- Organizer
  第56回日本神経学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-23228001
[Presentation] 18F-AV45(Florbetapir)によるSUVR値とeZIS z-score値との比較検討2015
- Author(s)
  柴田俊秀・米澤久司・高橋純子・工藤雅子・小原智子・鈴木真紗子・寺崎一典・佐々木敏秋・世良耕一郎・寺山靖夫
- Organizer
  第27回日本脳循環代謝学会総会
- Place of Presentation
  富山
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-23228001
[Presentation] 地域の医師会会員を対象とした認知症診療に関する意識調査2015
- Author(s)
  赤坂博・高橋純子・石塚直樹・藤澤豊・鈴木真紗子・小原智子・柴田俊秀・工藤雅子・米澤久司・寺山靖夫
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  青森
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-23228001
[Presentation] Amyloid imaging of dementia using the radioligand 18F-AV45(Florbetapir F 18)2015
- Author(s)
  Shibata, T., Yonezawa, H., Takahashi, J., Kudo, M., Obara, S., Suzuk,i M., Sasaki, T., Terasak,i K., Sera, K., Terayama, Y.
- Organizer
  第56回日本神経学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-23228001
[Presentation] 18Ｆ-ＡＶ45（Florbetapir）を用いた認知症におけるアミロイドイメージング
- Author(s)
  柴田俊英・米澤久司・高橋純子・工藤雅子・鈴木真沙子・小原智子・寺崎一典・佐々木敏秋・世良耕一郎・寺山靖夫
- Organizer
  第26回日本脳循環代謝学会総会
- Place of Presentation
  岡山市
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-23228001
[Presentation] 早期に認知症外来を受信するのはどういった症例か、外来初診患者の検討
- Author(s)
  赤坂　博・高橋純子・藤沢　豊・鈴木真沙子・石塚直樹・柴田俊英・小原智子・工藤雅子・米澤久司・寺山靖夫
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-29 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-23228001

1. ABE Takashi (30202667)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. TOHGI Hideo (90155490)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. UTSUGISAWA Kimiaki (00244913)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NAGANE Yuriko (10306003)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Suzuki Koichi (20003791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. GORYO Masanobu (80153774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHINADA Tetsuro (30271513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TERAYAMA Yasuo (70146596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. YOSHIOKA Yoshichika (00174897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAGATA Munehisa (00295974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SASAKI Makoto (80205864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. OIKAWA Hirobumi (10337157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKAHASHI Junko (00423989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. SUZUKI Mitsuru (10196876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAHASHI Satoshi 高橋 智

Research Projects

Research Products

Co-Researchers

Structure and function of an improving factor in hippocampal impairment originated from the silkworm-parasitic fungus (Paecilomyces tenuipes) and practical use for human brain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo imaging of dopaminergic and noradrenergic neurons using neuromelanin-sensitive MRI

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene expression profile of aging human brain and its in vitro model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Changes with age in DNA methylation and transcription in human cerebral cortex.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

筋緊張性ジストロフィー症の知能障害-遺伝子不安定領域、脳循環、海馬萎縮の検討-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Selective Vulnerability of neurons in age-related neuronal death and its molecular mechanisms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

老年期痴呆における髄液中抗酸化物質および神経伝達物質の変化とその病態生化学的意義Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alterations in concentrations of neurotransmitters in cerebrospinal fluid in patients with Parkinson's disease.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 18F-AV45(Florbetapir F18)を用いた認知症における脳アミロイドイメージング2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Detection of early changes in the parahippocampal and posterior cingulum bundles during mild cognitive impairment by using high-resolution multi-parametric diffusion tensor imaging2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer's disease: High-resolution fast spin-echo T1weighted imaging2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 18Ｆ-ＡＶ45（Ｆｌｏｒｂｅｔａｐｉｒ）を用いた脳アミロイドイメージング2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease2006

Author(s)

Journal Title

Description

Data Source

[Presentation] カイコ冬虫夏草に由来する海馬修復因子の精製と機能解析2015

Author(s)

Organizer

TAKAHASHI Satoshi 高橋智