MATSUMOTO Hiroko 松本裕子

… Alternative Names

松本裕子マツモトヒロコ

Less

Researcher Number	50221594
Other IDs
Affiliation (Current)	2025: 日本大学, 松戸歯学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2018: 日本大学, 松戸歯学部, 講師 2013: 日本大学, 松戸歯学部, 講師 2011 – 2012: 日本大学, 歯学部, 講師 2003 – 2006: Nihon University, School of Dentistry at Matsudo, Lecturer (Full-Time), 松戸歯学部, 講師 1998 – 2001: Nihon University, Nihon University School of Dentistry at Matsudo, Department of, 松戸歯学部, 助手 1997: 日本大学, 松戸歯学部, 副手 1992 – 1995: 日本大学, 松戸歯学部, 副手
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学) / Surgical dentistry Except Principal Investigator 病態科学系歯学(含放射線系歯学) / Surgical dentistry / Surgical dentistry / Functional basic dentistry / 畜産化学
Keywords	Principal Investigator IL-1α / HO-1-N-1 cell / PMA / IL-1β / ESE / NSAID / 転写因子 / 歯肉肥厚 / フェニトイン / ニフェジピン … More / カルシウム拮抗薬 / MAP kinase / ATF-2 / MAP Kinase / Akt / 抗アポトーシ作用 / 抗アポトーシス作用 / プロポフォール / 静脈麻酔薬 / transcription factor / buccal mucosa carcinoma-derived cell / ESE-3 / HO-1-N-1細胞 / 口腔扁平上皮癌由来上皮様細胞 / HO-1-N-1 / [Ca^<2+>]i / pHi / Gingival Overgrowth / Human Gingival Fibroblast / protein phosphorylation / Nifedipine / Calcium Channel Blocker / 細胞内Ca濃度 / 細胞内pH / 蛋白リン酸化 / 歯肉培養線維芽細胞 / 歯肉増殖症 / 炎症性因子 / ets遺伝子 / 薬物性歯肉肥厚 / Ets遺伝子 / ets-1 / 細胞周期 / 細胞増殖 / 細胞内カルシウム濃度 / 線維芽細胞 … More Except Principal Investigator 分離頻度 / 歯肉線維芽細胞 / 皮下膿瘍 / 歯性感染症 / bFGF / antimicrobial susceptibility / Staphylococcus aureus / 感受性 / 黄色ブドウ球菌 / メチシリン耐性黄色ブドウ球菌 / Nifedipine / カルシウム拮抗薬 / ニフェジピン / 歯肉肥厚 / メチシリン耐性ブドウ球菌 / BMC / BMD / pQCT / incidence of isolation / odontogenic infection / Staphylococcus epidermidis / 抗菌薬感受性 / 白色ブドウ球菌 / Human Gingival Fibroblast / Intracellular Signaling / 細胞内情報伝達 / methicillin-resistant Staphylococcus aureus / 細胞増殖 / ブラジキニン / subcutanus abscess / methicillin-resistant Staphylococcus epidermidis / methicillin-resistant staphylococci / メチシリン耐性白色ブドウ球菌 / Antimicrobial susceptibility / Incidence of isolation / Odontogenic infection / Methicillin-resistant staphylococci / メシシリン耐性白色ブドウ球菌 / gingival overgrowth / cyclin-dependent kinase (CDK) / cyclin / cell growth / cell cycle / gingival fibroblast / nifedipine / 歯肉培養線維芽細胞 / 歯肉増殖症 / p38MAPK / 歯肉増殖 / サイクリン依存性キナーゼ / サイクリン / 細胞周期 / Trabecular bone / Femur / Rat / Mandible / Osteoporosis / 海綿骨 / 下顎骨 / 大腿骨 / ラット / 実験的骨粗鬆症 / Rats and Dogs / Experimental Gingival Overgrowth / ジクロフェナクナトリウム / メフェナム酸 / インドメタシン / テニダップ / 合成抗炎症薬 / 細胞内pH / 細胞内カルシウム / 歯肉肥厚の治療 / NIFEDIPINE / TENIDAP / subcutaneous abscess / methicillin-resistant coagulase negative staphylococci / 薬剤感受性 / コアグラーゼ陰性メチシリン耐性ブドウ球菌 / メチシリン耐性コアグラーゼ陰性ブドウ球菌 / Gingival Overgrowth / Calcium Channel Blockers / IL-1α / リン酸化蛋白質 / cAMP / 蛋白リン酸化 / ヒト歯肉線維芽細胞 / odontogenic and oral infections / incidence / 歯性・口腔感染症 / Bradykinin / Intracellular calcium resoinse / Tissue culture / Gingival fibroblasts / Gingival hyperplasia / 細胞内カルシウム濃度 / カルシウム取り込み / コラーゲン合成能 / 線維芽細胞 / カルシウム拮抗剤 / ヒスタミン / フェニトン / DNA合成能 / 細胞内カルシウム応答 / 組織培養 Less

Effect of intravenous anesthetic agent on inflammasome in human bronchial smooth muscle cellPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Hiroko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Mechanism of gingival overgrowth caused by medication - Expression and role of ets transcription factor -Principal Investigator
- Principal Investigator
  
  MATSUMOTO Hiroko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Ets family expression in cultured cells from oral tissuePrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Hiroko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Methicillin-resistant staphylococci isolated from odontogenic infection
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Cell Growth and Cell Cycle in Nifedipine-Reactive Human Gingival FibroblastsPrincipal Investigator
- Principal Investigator
  
  FUJII Akira, 松本裕子
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
Clinical and Bacteriological study of methicillin-resistant staphylococci isolated from odontogenic infection.
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Mandible Bone Change in Osteoporosis Rats and Therapeutic Treatment
- Principal Investigator
  
  AKIRA Fujii
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
Clarification of Intracellular Signal Transductions in Nifedipine-Reactive Human Gingival FibroblastsPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Hiroko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
TREATMENT OF GINGIVAL OVERGROWTH CAUSED BY MEDICATION
- Principal Investigator
  
  FUJII Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
EFFECT OF NIFEDIPINE ON INTRACELLULAR SIGNAL TRANSDUCTIONS IN HUMAN GINGIVAL FIBROBLASTS
- Principal Investigator
  
  FUJII Akira
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
Incidence of isolation and antimicrobial susceptibility of methicillin-resistant coagulase negative staphylococci isolated from odontogenic infection
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
薬物性歯肉肥厚の発症機序の解明(特にニフェジピン及びフェニトイン感受性歯肉培養細胞の細胞特性について)Principal Investigator
- Principal Investigator
  
  松本裕子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
Incidence of isolation and antimicrobial
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Influence (Gingival Hyperplasia) of Nifedipine in Oral Region
- Principal Investigator
  
  FUJII Akira
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  畜産化学
- Research Institution
  Nihon University

All 2019 2018 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] The Inhibitory Action of Amlodipine for TNF-α-induced Apoptosis in Cultured Human Gingival Fibroblasts2012
- Author(s)
  Reiri Takeuchi，Hiroko Matsumoto， Yoshiaki Akimoto，Akira Fujii
- Journal Title
  
  Oral Therap Pharmacol
  
  Volume: 31(2) Pages: 45-52
- NAID
  10031168920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592779
[Journal Article] Inhibition of G1 Cell Cycle Arrest in Human Gingival Fibroblasts Exposed to Phenytoin2012
- Author(s)
  Reiri Takeuchi，Hiroko Matsumoto， Yoshiaki Akimoto，Akira Fujii
- Journal Title
  
  Fundam Clin Pharmacol
  
  Volume: 2012 Issue: 1 Pages: 1-6
- DOI
  10.1111/j.1472-8206.2012.01065.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592779
[Journal Article] The Inhibitory, Action of Amlodipine for TNF-α-induced Apopto- sis in Cultured Human Gingival Fibro- blasts2012
- Author(s)
  Takeuchi R,Matsumoto H,Akimoto Y,Fujii A
- Journal Title
  
  歯科薬物療法
  
  Volume: 31(2) Pages: 45-52
- NAID
  10031168920
- URL
  https://www.jstage.jst.go.jp/browse/jsotp/31/2/_contents/-char/ja
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Propofol reduces apoptosis through PI3K/Akt pathway in alveolar epithelial cells2019
- Author(s)
  Matsumoto H, Yamaguchi H, Takeuchi R, Nishimura H, Komiya M, Shibutani K
- Organizer
  IADR2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11325
[Presentation] H2O2によって誘導されたAkt活性化に対するプロポフォールの影響2018
- Author(s)
  松本裕子，山口秀紀，小野眞紀子，竹内麗理，小宮正道，渋谷　鑛
- Organizer
  第38回日本歯科薬物療法学会
- Data Source
  KAKENHI-PROJECT-15K11325
[Presentation] Effect of phenytoin on caspase activity in cultured human gingival fibroblasts2014
- Author(s)
  Reiri Takeuchi, Makiko Ono, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
- Organizer
  第34回日本歯科薬物療法学会
- Place of Presentation
  大阪歯科大学創立100周年記念館（大阪）
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] 18-alpha- glycyrrhetinic acid suppresses G1/S- phase transition and induces apoptosis in gingival fibroblast isolated from a patient that presented with nifedi- pine-induced gingival overgrowth2014
- Author(s)
  Takeuchi R, Ono M, Arikawa K, Akimoto Y, Fujii A, Matsumoto H
- Organizer
  17th World Congress on Basic & Clinical Pharmacology
- Place of Presentation
  Cape Town International Convention Center (Cape Town)
- Year and Date
  2014-07-13
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] 18-alpha-glycyrrhetinic acid suppresses G1/S-phase transition and induces apoptosis in gingival fibroblast isolated from a patient that presented with nifedipine-induced gingival overgrowth2014
- Author(s)
  Reiri Takeuchi, Makiko Ono, Kazumune Arikawa, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
- Organizer
  17th World Congress on Basic & Clinical Pharmacology
- Place of Presentation
  Cape Town International Convention Centre (Cape Town)
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Effect of phenytoin on caspase activity in cultured human gingival fibroblasts2014
- Author(s)
  Takeuchi R, Ono M, Akimoto Y, Fujii A, Matsumoto H
- Organizer
  第34回日本歯科薬物療法学会
- Place of Presentation
  大阪歯科大学(大阪)
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Tentative Pharmaco- therapy for Nifedipine-induced Gin- gival Overgrowth using 18α-glycyr- rhetinic Acid2013
- Author(s)
  Takeuchi R, Ono M, Akimoto Y, Fujii A, Matsumoto H
- Organizer
  第33回日本歯科薬物療法学会
- Place of Presentation
  東京医科歯科大学(東京)
- Year and Date
  2013-06-14
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Tentative Pharmacotherapy for Nifedipine-induced Gingival Overgrowth using 18α-glycyrrhetinic Acid2013
- Author(s)
  Reiri Takeuchi, Makiko Ono, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
- Organizer
  第33回日本歯科薬物療法学会
- Place of Presentation
  東京医科歯科大学（東京）
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] The Mechanism of Phenytoin-induced Gingival Overgrowth2012
- Author(s)
  Reiri Takeuchi，Hiroko Matsumoto， Yoshiaki Akimoto，Akira Fujii
- Organizer
  第32回日本歯科薬物療法学会
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] The Mechanism of Phenytoin- induced Gingival Overgrowth2011
- Author(s)
  Takeuchi R, Matsumoto H, Akimoto Y, Fujii A
- Organizer
  第32回日本歯科薬物療法学会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] The Mechanism of Nifedipine- induced Gingival Overgrowth2011
- Author(s)
  Takeuchi R, Matsumoto H, Akimoto Y, Fujii A
- Organizer
  第53回歯科基礎医学会
- Place of Presentation
  長良川国際会議場(岐阜)
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] アムロジピンによる歯肉肥厚の発症機序2011
- Author(s)
  松本裕子,竹内麗理,小野眞紀子,秋元芳明,藤井彰
- Organizer
  第13回応用薬理シンポジウム
- Place of Presentation
  日本大学薬学部(船橋)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-23592779

1. FUJII Akira (70102564)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. AKIMOTO Yoshiaki (10147720)

# of Collaborated Projects: 12 results

# of Collaborated Products: 13 results
3. ONO Makiko (00267113)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. YAMAMOTO Hirotugu (00102591)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. NISHIMURA Hitoshi (10198509)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SHIBUTANI Jun (20206147)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. TAKEUCHI Reiri (60419778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
8. KANEDA Takashi (40185947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HIRAYAMA Teruyasu (10189871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山根潤一 (20220428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中尾寿美 (20102577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 渋谷鉱 (70130523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 山口秀紀 (50220273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 小宮正道 (40186812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 池田眞紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

MATSUMOTO Hiroko 松本 裕子

松本 裕子 マツモト ヒロコ

Research Projects

Research Products

Co-Researchers

Effect of intravenous anesthetic agent on inflammasome in human bronchial smooth muscle cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of gingival overgrowth caused by medication - Expression and role of ets transcription factor -Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ets family expression in cultured cells from oral tissuePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell Growth and Cell Cycle in Nifedipine-Reactive Human Gingival FibroblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of Intracellular Signal Transductions in Nifedipine-Reactive Human Gingival FibroblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

薬物性歯肉肥厚の発症機序の解明(特にニフェジピン及びフェニトイン感受性歯肉培養細胞の細胞特性について)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

MATSUMOTO Hiroko 松本裕子

松本裕子マツモトヒロコ