KONO Yumi 河野由美

… Alternative Names

河野由美コウノユミ

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Researcher Number	50243390
Other IDs
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2023: 自治医科大学, 医学部, 教授 2016: 自治医科大学, 小児科, 教授 2001 – 2006: 東京女子医科大学, 医学部, 講師 1996 – 2000: 鳥取大学, 医学部・附属病院, 助手 1996: Tottori University, Faculty of Medicine, Research associate, 医学部付属病院, 助手 1995: 鳥取大学, 医学部・付属病院, 助手 1994: 鳥取大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine / Basic Section 52050:Embryonic medicine and pediatrics-related / Embryonic/Neonatal medicine Except Principal Investigator Pediatrics / Embryonic/Neonatal medicine
Keywords	Principal Investigator メチル化 / 低出生体重児 / RT-PCR / antioxidant enzyme / CYP1A1 / lactation / dioxin / 発達障害 / 早産児 / ストレス反応 … More / 胎児 / 喫煙 / 腎疾患 / 心血管系疾患 / 早産低出生体重児 / 妊娠高血圧症候群 / 早産 / ストレス / newborn rat / 授乳 / neonate / 臍帯血 / CYP1B1 / 新生児 / ダイオキシン / 新生仔 / グルココルチコイド / 精神発達 / 喫煙暴露 / 低出生体重 / 受動喫煙 … More Except Principal Investigator 母乳 / 新生児 / 胆汁うっ滞 / 脳エネルギー産生 / 脳グリコーゲン / 痙性両麻痺 / 脳性まひ / 脳エネルギー代謝 / 低酸素性虚血性脳症 / 脳型ホスホリラーゼ / グリコーゲン代謝 / 遺伝子多型 / アストロサイト / 嫌気性解糖 / グリコーゲン / 脳性麻痺 / 神経後遺症 / 新生児仮死 / intracellular cyclic AMP level / breast milk / multi variate regression of bile flow / osmolarity / bile salt-dependent flow / basolateral plasma membrane / sinusoidal bile salt transport protein / biliary obstruction / アイソトープ / 生理的胆汁うっ滞 / 腸管循環 / 胆汁酸 / 小腸ループ法 / absorption / bile acid / 人工乳 / 人乳 / 胆汁酸消失率 / ラット小腸ループ法 / 放射性胆汁酸 / 胆汁酸輸送蛋白 / 部分肝切除 / cAMP / 胆汁酸依存性胆汁 / テオフィリン / ビタミンK / CHOLESTASIS / NEONATAL HEPATOCYTE / THREE-DIMENSIONAL CULTURE / EGF / エストラジオール / 肝内胆汁うっ滞 / 上皮増殖因子 / 毛細胆管 / スフェロイド肝細胞 / 新生仔 / 培養肝細胞 / 新生仔肝細胞 / 三次元培養 / 血 / 低ナトリウム血症 / 血圧 / 低Na血症 / 低出生体重児 / 早産児 Less

Methylation of genes related to cardiovascular and chronic kidney diseases in preterm low birth weight infants born to mothers with hypertensive disorders of pregnancyPrincipal Investigator
- Principal Investigator
  
  河野由美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Jichi Medical University
DNA methylation levels of stress-response related genes and behavior development in low birth weight infantsPrincipal Investigator
- Principal Investigator
  
  Kono Yumi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Jichi Medical University
DNA methylation of human glucocorticoid receptor gene (NR3C1) and stress response in low birth weight infantsPrincipal Investigator
- Principal Investigator
  
  Kono Yumi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Jichi Medical University
A Study on Cerebral Protection Mechanism against Neonatal Asphyxia: Treatment strategy Based on Brain Glycogen Metabolism
- Principal Investigator
  
  SUGIE Hideo
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokoha University
  Jichi Medical University
早産児認める低Na血症が成長後の血圧に及ぼす影響に関する基礎研究
- Principal Investigator
  
  楠田聡
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokyo Women's Medical University
低出生体重児における胎児期の喫煙暴露と精神運動発達,行動障害の関連に関する研究Principal Investigator
- Principal Investigator
  
  河野由美
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokyo Women's Medical University
Toxicity and its mechanism of dioxin-like chemicals in infants through their mothers exposed during a pregnancy and lactational period.Principal Investigator
- Principal Investigator
  
  KONO Yumi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokyo Woman's Medical University
  Tottori University
Physiological intrahepatic cholestasis by breast milk
- Principal Investigator
  
  MURA Tatsuo, 新澤毅
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tottori University
A study on mechanisms of intrahepatic cholestasis using neonatal rat hepatocytes cultured in three-dimensions.
- Principal Investigator
  
  SHIRAKI Kazuo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tottori University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2005

All Journal Article Presentation

[Journal Article] A Retrospective Cohort Study on Mortality and Neurodevelopmental Outcomes of Preterm Very Low Birth Weight Infants Born to Mothers with Hypertensive Disorders of Pregnancy2021
- Author(s)
  Kono Yumi、Yonemoto Naohiro、Nakanishi Hidehiko、Hosono Shigeharu、Hirano Shinya、Kusuda Satoshi、Fujimura Masanori、for the Neonatal Research Network Japan
- Journal Title
  
  American Journal of Perinatology
  
  Volume: － Issue: 13 Pages: 1465-1477
- DOI
  10.1055/s-0041-1722874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07779
[Journal Article] Neurodevelopmental outcomes of very low birth weight infants in the Neonatal Research Network of Japan: Importance of NICU graduate follow-up.2020
- Author(s)
  Kono Y
- Journal Title
  
  Clin Exp Pediatr.
  
  Volume: － Issue: 7 Pages: 313-321
- DOI
  10.3345/cep.2020.01312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10190
[Journal Article] hanges in survival and neurodevelopmental outcomes of infants born at <25 weeks’ gestation: a retrospective observational study in tertiary centers in Japan.2018
- Author(s)
  Kono Y, Yonemoto N, Nakanishi H, Kusuda S, Fujimura M
- Journal Title
  
  BMJ Paediatr Open
  
  Volume: 2 Issue: 1 Pages: e000211-e000211
- DOI
  10.1136/bmjpo-2017-000211
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10190
[Journal Article] 早産・低出生体重児の発達障害2017
- Author(s)
  河野由美
- Journal Title
  
  医学のあゆみ
  
  Volume: 260 Pages: 231-236
- Data Source
  KAKENHI-PROJECT-26461641
[Journal Article] 22、23週　新生児　長期予後の現状2016
- Author(s)
  河野由美
- Journal Title
  
  周産期医学
  
  Volume: 46 Pages: 845-849
- Data Source
  KAKENHI-PROJECT-26461641
[Journal Article] Long-term outcomes of antenatal corticosteroids treatment in very preterm infants after chorioamnionitis2015
- Author(s)
  Miyazaki K, Furuhashi M, Ishikawa K, Tamakoshi K, Hayashi K, Kai A, Ishikawa H, Murabayashi N, Ikeda T, Kono Y, Kusuda S, Fujimura M.
- Journal Title
  
  Arch Gynecol Obstet.
  
  Volume: 29 Issue: 6 Pages: 1239-1246
- DOI
  10.1007/s00404-015-3762-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461641
[Journal Article] The Effects of Antenatal Corticosteroids on Short- and Long-Term Outcomes in Small-for-Gestational-Age Infants.2015
- Author(s)
  Ishikawa H, Miyazaki K, Murabayashi N, Kono Y, et al.
- Journal Title
  
  Int J Med Sci
  
  Volume: 12 Issue: 4 Pages: 295-300
- DOI
  10.7150/ijms.11523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461641
[Journal Article] Perinatal dioxin exposure and psychosocial and behavioral development in school-aged children.2015
- Author(s)
  Kono Y, Oka A, Tada H, Itabashi K, Matsui E, Nakamura Y
- Journal Title
  
  Early Hum Dev
  
  Volume: 91 Issue: 9 Pages: 499-503
- DOI
  10.1016/j.earlhumdev.2015.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461641
[Journal Article] Developmental assessment of VLBW infants at 18months of age: A comparison study between KSPD and Bayley III.2015
- Author(s)
  Kono Y, Yonemoto N, Kusuda S, Hirano S, Iwata O, Tanaka K, Nakazawa J.
- Journal Title
  
  Brain Dev.
  
  Volume: 38(4) Issue: 4 Pages: 377-385
- DOI
  10.1016/j.braindev.2015.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24119004, KAKENHI-PROJECT-24591533, KAKENHI-PROJECT-26461641
[Journal Article] 極低出生体重児の予後2015
- Author(s)
  河野由美
- Journal Title
  
  小児内科
  
  Volume: 47 Pages: 316-322
- Data Source
  KAKENHI-PROJECT-26461641
[Journal Article] 非進行性肝型と考えられる糖原病IV型の1例2013
- Author(s)
  河野香, 安達昌功, 朝倉由美, 室谷浩二, 鹿間芳明, 赤城邦彦, 田中祐吉, 福田冬季子, 杉江秀夫
- Journal Title
  
  日本小児科学会雑誌
  
  Volume: 117 Pages: 1883-1887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461652
[Journal Article] 周産期の栄養と身体発育2005
- Author(s)
  河野由美, 三科潤
- Journal Title
  
  周産期医学 35, suppl
  
  Pages: 509-513
- Data Source
  KAKENHI-PROJECT-15659255
[Presentation] Survival and neurodevelopmental outcomes of infants born at less than 25 weeks' gestation in the Neonatal Research Network of Japan2019
- Author(s)
  Yumi Kono
- Organizer
  the 69th Korean Pediatric Society Annual Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10190
[Presentation] Changes in outcomes at 3 years of age in infants born at less than 25 weeks' gestation2017
- Author(s)
  Yumi Kono
- Organizer
  the Pediatric Academic　Societies (PAS) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461641
[Presentation] 超早産児の予後2015
- Author(s)
  河野由美
- Organizer
  日本小児科学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-04-19
- Data Source
  KAKENHI-PROJECT-26461641
[Presentation] Developmental assessment of VLBW infants at 18 months of age: a comparison study between Bayley III and KSPD.2015
- Author(s)
  Kono Y, Yonemoto N, Kusuda S, Hirano S, Iwata O, Tanaka K, Nakazawa J.
- Organizer
  The 11th Congress of Asian Society for Pediatric Research
- Place of Presentation
  Osaka
- Year and Date
  2015-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461641
[Presentation] SGA児の長期予後改善にむけた周産期管理 SGA児の予後2015
- Author(s)
  河野由美
- Organizer
  日本周産期・新生児医学会
- Place of Presentation
  福岡
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26461641
[Presentation] Trends of Neurodevelopmental Outcomes of Extremely Preterm Infants Born at 22 - 25 Weeks’ Gestation in Neonatal Research Network Japan　 The Hot Topics in Neonatology2015
- Author(s)
  Kono Y., Yonemoto N., Kusuda S., Fujimura M.
- Organizer
  The Hot Topics in Neonatology
- Place of Presentation
  Washington DC
- Year and Date
  2015-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461641
[Presentation] Neurodevelopmental Outcome of VLBW Infants in Neonatal Research Network Japan2014
- Author(s)
  Yumi Kono
- Organizer
  the 27th Annual Autumn Meeting of the Korean Society of Perinatology
- Place of Presentation
  Seuol, Korea
- Year and Date
  2014-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-26461641

1. MURA Tatsuo (80093631)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 三科潤 (60277192)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. JINBO Eriko (20291651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIRAKI Kazuo (60010229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 佐久間泉 (80246644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SUZUKI Yume (40458302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATANO Miyuki (90458315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAGATA Ikuo (50252846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OGURA Yoshio (00135849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUGIE Hideo (60119980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. FUKUDA Tokiko (10458268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. HIRASAWA Kyoko (50316709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松田義雄 (10339020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 楠田聡 (50372983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 仁志田博司 (80104553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 福井千佳 (70349695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 増本健一 (50385415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 新澤毅 (70216216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 神崎晋 (90224873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 大口昭英 (10306136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KONO Yumi 河野 由美

河野 由美 コウノ ユミ

Research Projects

Research Products

Co-Researchers

Methylation of genes related to cardiovascular and chronic kidney diseases in preterm low birth weight infants born to mothers with hypertensive disorders of pregnancyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DNA methylation levels of stress-response related genes and behavior development in low birth weight infantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA methylation of human glucocorticoid receptor gene (NR3C1) and stress response in low birth weight infantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Study on Cerebral Protection Mechanism against Neonatal Asphyxia: Treatment strategy Based on Brain Glycogen Metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

早産児認める低Na血症が成長後の血圧に及ぼす影響に関する基礎研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低出生体重児における胎児期の喫煙暴露と精神運動発達,行動障害の関連に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Toxicity and its mechanism of dioxin-like chemicals in infants through their mothers exposed during a pregnancy and lactational period.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological intrahepatic cholestasis by breast milk

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on mechanisms of intrahepatic cholestasis using neonatal rat hepatocytes cultured in three-dimensions.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A Retrospective Cohort Study on Mortality and Neurodevelopmental Outcomes of Preterm Very Low Birth Weight Infants Born to Mothers with Hypertensive Disorders of Pregnancy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurodevelopmental outcomes of very low birth weight infants in the Neonatal Research Network of Japan: Importance of NICU graduate follow-up.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] hanges in survival and neurodevelopmental outcomes of infants born at <25 weeks’ gestation: a retrospective observational study in tertiary centers in Japan.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 早産・低出生体重児の発達障害2017

Author(s)

Journal Title

Data Source

[Journal Article] 22、23週 新生児 長期予後の現状2016

Author(s)

KONO Yumi 河野由美

河野由美コウノユミ

[Journal Article] 22、23週　新生児　長期予後の現状2016

[Presentation] Trends of Neurodevelopmental Outcomes of Extremely Preterm Infants Born at 22 - 25 Weeks’ Gestation in Neonatal Research Network Japan　 The Hot Topics in Neonatology2015