MATSUZAKI Toshihiro 松崎俊博

… Alternative Names

松崎俊博マツザキトシヒロ

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Researcher Number	50244330
Other IDs
Affiliation (based on the past Project Information) *help	2023: 琉球大学, 医学(系)研究科(研究院), 助教 2022: 琉球大学, 医学研究科, 助教 2018 – 2021: 琉球大学, 医学(系)研究科(研究院), 助教 2015 – 2018: 琉球大学, 医学研究科, 助教 2013: 琉球大学, 大学院医学研究科, 助教 … More 2012 – 2013: 琉球大学, 医学(系)研究科(研究院), 助教 2010 – 2011: 琉球大学, 医学研究科, 助教 1996: 琉球大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 56030:Urology-related / Anesthesiology / Urology / General pharmacology / General internal medicine (including Psychosomatic medicine)
Keywords	Principal Investigator cyclic GMP / イソソルビド / ニトロプルシッド / ニトログリセリン / グルタチオンS-トランスフェラーゼ / グルタチオン / 耐性 / NO Except Principal Investigator 一酸化窒素 / 一酸化窒素合成酵素 … More / テストステロン / マウス / 虚血性心疾患 / 虚血性心血管疾患 / 多様性 / 遺伝子欠損マウス / Wnt/β-catenin経路 / 呼吸器疾患 / 肺気腫 / 硝酸ナトリウム / 硝酸塩 / NOx / テストステロン補充 / エストロゲン / 欠損 / 性差 / ミトコンドリア機能不全 / 酸化ストレス / 再灌流 / 脳虚血 / 心筋梗塞 / 遺伝子改変マウス / 急性心筋梗塞 / 骨髄前駆細胞 / 慢性腎臓病 / 動脈硬化 / ノックアウトマウス / 臓器連関 / 循環器・高血圧 / 循環器学 / 薬理学 / メタボリックシンドローム / 東洋医学 / 漢方薬 Less

Elucidation of the role of the nitric oxide synthase system in the pathogenesis of respiratory diseases
- Principal Investigator
  
  Tsutsui Masato
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  University of the Ryukyus
The evaluation of the utility of in vivo NO level regulation for ischemic cardiovascular disease caused by androgen supplementation.
- Principal Investigator
  
  Sakanashi Mayuko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kinjo Gakuin University
Elucidation of the exacerbation mechanisms of ischemic cardiovascular disease induced by testosterone.
- Principal Investigator
  
  SAKANASHI MAYUKO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kinjo Gakuin University
  University of the Ryukyus
An attempt to apply to new therapy the phenomenon that complete disruption of all nitric oxide synthase genes reduces cerebral infarct volume.
- Principal Investigator
  
  Kubota Haruaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology
- Research Institution
  University of the Ryukyus
Basic research on the role of the nitric oxide synthase system in organ connection
- Principal Investigator
  
  TSUTSUI Masato
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of the Ryukyus
Elucidation of anti-metabolic syndrome effects by San'oshashinto
- Principal Investigator
  
  SAKANASHI Mayuko
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of the Ryukyus
ニトロ化合物による血管弛緩効果ならびに耐性発現に関する研究Principal Investigator
- Principal Investigator
  
  松崎俊博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of the Ryukyus

All 2020 2018 2017 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice.2017
- Author(s)
  Kina-Tanada M, Sakanashi M, Tanimoto A, Kaname T, Matsuzaki T, Noguchi K, Uchida T, Nakasone J, Kozuka C, Ishida M, Kubota H, Taira Y, Totsuka Y, Kina SI, Sunakawa H, Omura J, Satoh K, Shimokawa H, Yanagihara N, Maeda S, Ohya Y, Matsushita M, Masuzaki H, Arasaki A, Tsutsui M.
- Journal Title
  
  Diabetologia.
  
  Volume: 60 Issue: 6 Pages: 1138-1152
- DOI
  10.1007/s00125-017-4259-6
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-15H06519, KAKENHI-PROJECT-15K15046, KAKENHI-PROJECT-15K21251, KAKENHI-PROJECT-15K08238, KAKENHI-PROJECT-15K10644, KAKENHI-PROJECT-16K09519, KAKENHI-PROJECT-16H00594, KAKENHI-PROJECT-17K09839
[Journal Article] Long-Term Treatment With San'o-Shashin-To, a Kampo Medicine, Markedly Ameliorates Cardiac Ischemia-Reperfusion Injury in Ovariectomized Rats via the Redox-Dependent Mechanism2013
- Author(s)
  Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Junko Nakasone, Makiko Sakanashi, Taro Uchida, Mika Kina-Tanada, Haruaki Kubota, Kumiko Arakaki, Akihide Tanimoto, Nobuyuki Yanagihara, Matao Sakanashi, Yusuke Ohya , Hiroaki Masuzaki, Shogo Ishiuchi, Kazuhiro Sugahara, Masato Tsutsui
- Journal Title
  
  Circulation Journal
  
  Volume: vol. 77, No.7 Pages: 1827-37
- NAID
  10031173765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590660
[Journal Article] Na(+)/H(+) exchanger inhibitor induces vasorelaxation through nitric oxide production in endothelial cells via intracellular acidification-associated Ca2(+) mobilization.2013
- Author(s)
  Sasahara T, Yayama K, Matsuzaki T, Tsutsui M, Okamoto H.
- Journal Title
  
  Vascu Pharmacol
  
  Volume: 58(4) Issue: 4 Pages: 319-325
- DOI
  10.1016/j.vph.2012.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590093, KAKENHI-PROJECT-23590305
[Journal Article] Long-Term Treatment With San’o-Shashin-To, a Kampo Medicine, Markedly Ameliorates Cardiac Ischemia-Reperfusion Injury in Ovariectomized Rats via the Redox-Dependent Mechanism2013
- Author(s)
  Sakanashi M, Matsuzaki T, Noguchi K, Nakasone J, Sakanashi M, Uchida T, Kina-Tanada M, Kubota H, Arakaki K, Tanimoto A, Yanagihara N, Sakanashi M, Ohya Y, Masuzaki H, Ishiuchi S, Sugahara K, Tsutsui M
- Journal Title
  
  Circ J
  
  Volume: 77 Issue: 7 Pages: 1827-1837
- DOI
  10.1253/circj.CJ-12-1434
- NAID
  10031173765
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590660, KAKENHI-PROJECT-23390376, KAKENHI-PROJECT-23590159, KAKENHI-PROJECT-23590305, KAKENHI-PROJECT-23617035, KAKENHI-PROJECT-23790300, KAKENHI-PROJECT-24590324
[Journal Article] Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo.2011
- Author(s)
  Noguchi K, Hamadate N, Matsuzaki T, Sakanashi M, Nakasone J, Uchida T, Arakaki K, Kubota H, Ishiuchi S, Masuzaki H, Sugahara K, Ohya Y, Sakanashi M, Tsutsui M.
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590305
[Journal Article] Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo2011
- Author(s)
  Noguchi K, Hamadate N, Matsuzaki T, Sakanashi M, Nakasone J, Uchida T, Arakaki K, Kubota H, Ishiuchi S, Masuzaki H, Sugahara K, Ohya Y, Sakanashi M, Tsutsui M
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 301 Issue: 3 Pages: H721-H729
- DOI
  10.1152/ajpheart.01089.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590305, KAKENHI-PROJECT-23790300
[Presentation] 漢方薬による閉経モデルラットの心臓虚血再灌流障害軽減作用2020
- Author(s)
  坂梨まゆ子、松崎俊博、野口克彦、仲宗根淳子、筒井正人
- Organizer
  日本酸化ストレス学会東海支部第9回学術集会
- Data Source
  KAKENHI-PROJECT-18K09141
[Presentation] Sex Difference of Cardiovascular Death in the 2/3 Nephrectomized-Nitric Oxide Synthases Deficient Mice: Involvement of Androgen2018
- Author(s)
  Mayuko Sakanashi, Yuji Taira, Toshihiro Matsuzaki, Junko Nakasone, Haruaki Kubota, Katsuhiko Noguchi, Masato Tsutsui
- Organizer
  18th World congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10644
[Presentation] Deleterious effect of all nitric oxide synthases in cerebral infarction in male mice: involvements of sex difference and testosterone.2017
- Author(s)
  Tsutsui M, Kubota H, Noguchi K, Matsuzaki T, Sakanashi M, Nakasone J, Shimokawa H, Ohya Y, Sugahara K, Kakinohana M
- Organizer
  American Heart Association Scientific Sessions 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10644
[Presentation] Sex Difference in Sudden Death of 2/3 Nephrectomized Triple Nitric Oxide Synthases-Deficient Mice.2017
- Author(s)
  Tsutsui M, Sakanashi M, Taira Y, Matsuzaki T, Noguchi K, Nakasone J, Ohya Y, Shimokawa H
- Organizer
  The 8th Congress of the International Society for Gender Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10644
[Presentation] 低NO2-/NO3-食の長期的な摂取はメタボリックシンドロームを惹起する2017
- Author(s)
  坂梨まゆ子、喜名美香、野口克彦、松崎俊彦、仲宗根淳子、平良雄司、久保田陽秋、戸塚裕一、筒井正人
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K10644
[Presentation] 2/3腎摘NO合成酵素完全欠損マウスの突然死における性差2017
- Author(s)
  筒井正人、坂梨まゆ子、平良雄司、内田太郎、松崎俊博、野口克彦、仲宗根淳子、下川宏明
- Organizer
  第17回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10644
[Presentation] Development of an Experimentally Useful Model of Spontaneous Myocardial Infarction : 2/3 Nephrectomized Triple Nitric Oxide Synthases-Deficient Mouse2014
- Author(s)
  Uchida T, Furuno Y, Tanimoto H, Arakaki K, Kina M, Kubota H, Sakanashi M, Matsuzaki T, Noguchi K, Nakasone J, Ohya Y, Yanagihara N, Shimokawa H, Tamura M, Otsuji Y, Tsutsui M.
- Organizer
  The 78th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Tokyo International Forum, Tokyo, Japan
- Year and Date
  2014-03-22
- Data Source
  KAKENHI-PROJECT-23590305
[Presentation] The cardioprotective effects of San'oshashinto on ischemia/reperfusion injury in ovariectomized rats : involvement of emodin2014
- Author(s)
  Mayuko Sakanashi, Toshihiro Matsuzaki et al
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Year and Date
  2014-03-20
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] 三黄瀉心湯が実験的閉経モデルラットの心臓虚血再灌流障害におよぼす影響:エモジンの関与2014
- Author(s)
  坂梨まゆ子, 松崎俊博他
- Organizer
  日本薬学会第134回年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] San'o-shashin-to, a Kampo Medicine, Ameliorates Cardiac Ischemia/Reperfusion Injury in Ovariectomized Rats via Suppression of Peroxynitrite Formation and Restoration of Manganese Superoxide Dismutase Activities2013
- Author(s)
  Mayuko Sakanashi, Toshihiro Matsuzaki et al
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] Development of an experimentally useful animal model of spontaneous myocardial infarction2013
- Author(s)
  Uchida T, Furuno Y, Tanimoto A, Toyohira Y, Sakanashi M, Matsuzaki T, Noguchi K, Nakasone J, Ohya Y, Yanagihara N, Shimokawa H, Tamura M, Otsuji Y, Tsutsui M
- Organizer
  The 77th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Pacifico Yokohama, Yokohama, Japan
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PROJECT-23590305
[Presentation] 閉経モデルラットの心臓虚血再灌流障害に対する三黄瀉心湯の心保護作用:emodinの関与2013
- Author(s)
  坂梨まゆ子, 松崎俊博他
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2013-11-16
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] 三黄瀉心湯の長期投与レドックスに依存した機序を介して卵巣摘出ラットの心臓虚血再灌流障害を改善する2013
- Author(s)
  坂梨まゆ子、松崎俊博、野口克彦、仲宗根淳子、坂梨真木子、内田太郎、棚田美香、久保田陽秋、大屋祐輔、筒井正人
- Organizer
  第13回日本NO学会学術集会
- Place of Presentation
  沖縄県医師会館（沖縄）
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] 三黄瀉心湯の長期投与レドックスに依存した機序を介して卵巣摘出ラットの心臓虚血再灌流障害を改善する2013
- Author(s)
  坂梨まゆ子, 松崎俊博他
- Organizer
  第13回日本NO学会学術集会
- Place of Presentation
  沖縄
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] 卵巣摘出ラットの心臓虚血再灌流障害に対する三黄瀉心湯の心保護作用2012
- Author(s)
  坂梨まゆ子, 松崎俊博他
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] San-o-shashinto reduces cardiac ischemia-reperfusion injury in ovariectomized rats through selective activation of manganese superoxide dismutase2012
- Author(s)
  Mayuko Sakanashi, Toshihiro Matsuzaki et al
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] 三黄瀉心湯は卵巣摘出ラットの心臓虚血再灌流障害を改善する2012
- Author(s)
  坂梨まゆ子, 松崎俊博他
- Organizer
  第12回日本NO学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] 三黄瀉心湯の長期経口投与は高脂肪食負荷ラットの血管内皮機能障害および高脂血症を改善する2011
- Author(s)
  坂梨まゆ子, 松崎俊博他
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催/東日本大震災のため)
- Data Source
  KAKENHI-PROJECT-22590660
[Presentation] Increasing dihydrobiopterin causese dysfunction of endothelial nitric oxide synthase in rats in vivo.2011
- Author(s)
  Tsutsui M, Noguchi K, Matsuzaki T, Sakanashi M, Nakasone J, Uchida T, Arakaki K, Kubota H, Sugahara K, Ohya Y.
- Organizer
  American Heart Association, Scientific Sessions 2011
- Place of Presentation
  Orange County Convention Center, Orlando, USA
- Data Source
  KAKENHI-PROJECT-23590305
[Presentation] Development of an experimentally useful animal model of spontaneous myocardial infarction.
- Author(s)
  Uchida T, Furuno Y, Tanimoto A, Toyohira Y, Sakanashi M, Matsuzaki T, Noguchi K, Nakasone J, Ohya Y, Yanagihara N, Shimokawa H, Tamura M, Otsuji Y, Tsutsui M.
- Organizer
  The 77th Annual Scientific Meeting of the Japanese Circulation Society.
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23590305

1. SAKANASHI Mayuko (80363662)

# of Collaborated Projects: 5 results

# of Collaborated Products: 23 results
2. TSUTSUI Masato (70309962)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
3. NOGUCHI Katsuhiko (70156181)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
4. Kubota Haruaki (10600421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 坂梨又郎 (80040252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 安仁屋洋子 (90045055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANIMOTO Akihide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SATOH Kimio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. OKAMOTO Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 屋山勝俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUZAKI Toshihiro 松崎 俊博

松崎 俊博 マツザキ トシヒロ

Research Projects

Research Products

Co-Researchers

Elucidation of the role of the nitric oxide synthase system in the pathogenesis of respiratory diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The evaluation of the utility of in vivo NO level regulation for ischemic cardiovascular disease caused by androgen supplementation.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the exacerbation mechanisms of ischemic cardiovascular disease induced by testosterone.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An attempt to apply to new therapy the phenomenon that complete disruption of all nitric oxide synthase genes reduces cerebral infarct volume.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research on the role of the nitric oxide synthase system in organ connection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of anti-metabolic syndrome effects by San'oshashinto

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ニトロ化合物による血管弛緩効果ならびに耐性発現に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-Term Treatment With San'o-Shashin-To, a Kampo Medicine, Markedly Ameliorates Cardiac Ischemia-Reperfusion Injury in Ovariectomized Rats via the Redox-Dependent Mechanism2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Na(+)/H(+) exchanger inhibitor induces vasorelaxation through nitric oxide production in endothelial cells via intracellular acidification-associated Ca2(+) mobilization.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-Term Treatment With San&rsquo;o-Shashin-To, a Kampo Medicine, Markedly Ameliorates Cardiac Ischemia-Reperfusion Injury in Ovariectomized Rats via the Redox-Dependent Mechanism2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo.2011

Author(s)

Journal Title

Data Source

[Journal Article] Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] 漢方薬による閉経モデルラットの心臓虚血再灌流障害軽減作用2020

MATSUZAKI Toshihiro 松崎俊博

松崎俊博マツザキトシヒロ

[Journal Article] Long-Term Treatment With San’o-Shashin-To, a Kampo Medicine, Markedly Ameliorates Cardiac Ischemia-Reperfusion Injury in Ovariectomized Rats via the Redox-Dependent Mechanism2013