Kuwana Masataka 桑名正隆

… Alternative Names

KUWANA Masataka 桑名正隆

桑名正隆クワナマサタカ

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Researcher Number	50245479
Other IDs
External Links
Affiliation (Current)	2025: 日本医科大学, 大学院医学研究科, 大学院教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 日本医科大学, 大学院医学研究科, 大学院教授 2016: 日本医科大学, 大学院医学研究科, 教授 2014 – 2015: 日本医科大学, 医学(系)研究科(研究院), 教授 2014: 慶應義塾大学, 医学部, 講師 2007 – 2014: Keio University, School of Medicine, Associate Professor … More 2005 – 2006: Keio University, School of Medicine, Assistant Professor, 医学部, 助教授 2000 – 2005: Keio University, School of Medicine, Assistant Professor, 医学部, 講師 2000: 慶応義塾大学, 医学部, 講師 2000: 慶應義塾大学, 医学部, 専任講師 1997 – 1999: 慶應義塾大学, 医学部, 助手 1993: 慶応義塾大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学 / Basic Section 54020:Connective tissue disease and allergy-related / Hematology / Collagenous pathology/Allergology Except Principal Investigator 膠原病・アレルギー・感染症内科学 / Ophthalmology / Experimental pathology / 内科学一般 / Circulatory organs internal medicine / Dermatology
Keywords	Principal Investigator 単球 / 強皮症 / 線維化 / 自己反応性T細胞 / 自己抗体 / 血管新生 / 線維芽細胞 / 自己免疫疾患 / 全身性硬化症(強皮症) / 全身性強皮症 … More / 心筋 / 幹細胞 / 再生医療 / マクロファージ / 膠原病 / 血管内皮前駆細胞 / HLA / 主要組織適応抗原 / エピトープ / T細胞 / 皮膚 / トランスクリプトーム / 心筋炎 / バイオインフォマティクス / 間質性肺疾患 / I型インターフェロン / Platelets / Multipotential cells / Cerebral infraction / Monocytes / Vasculogenesis / Regeneration / Stem cells / 皮弁 / 血小板 / 多能性細胞 / 脳梗塞 / Genechip / Stem cell / Trans-differentiation / Differentiation / Monocyte / Regenerative medicine / 神経 / 遣伝子チップ / 遺伝子チップ / 分化転換 / 分化能 / Autoimmune disease / Immuno-therapy / Antiphospholipid antibody / Phospholipid / Thrombosis / T cell / Autoantibody / T細胞リセプター / 習慣性流産 / 抗原提示細胞 / 免疫療法 / 抗リン脂質抗体 / リン脂質 / 血栓症 / 動物モデル / 肺線維症 / 肺高血圧症 / 血管リモデリング / 肺動脈性肺高血圧症 / 膠原病学 / 末梢循環障害 / 血管再生 / ケモカイン / 脈管形成 / 移植 / 免疫不全マウス / 細胞傷害性T細胞 / MICA / マイクロサテライト / 細胞障害性T細胞 / ベーチェット病 / 翻訳後修飾 / トポイソメラーゼ / T細胞レセプター / 免疫トレランス / DNAトポイソメラーゼI … More Except Principal Investigator 関節リウマチ / 免疫学 / 末梢血単球 / Mesenchymal stem cell / Fibrosis / Fibroblast / Immunology / Hematopietic stem cell transplantation / Graft-versus-host disease / Dry eye / Ocular pathology / 骨髄 / マーカー / 涙腺 / 慢性移植片対宿主病 / 幹細胞 / 間葉系幹細胞 / 線維化 / 線維芽細胞 / 造血幹細胞移植 / 移植片対宿主病 / ドライアイ / 眼病理学 / Macrophage-colony stimulating factor / Adenovirus vector / Bone marrow chimera / Mouse model for arthritis / Monocytes / Rheumatoid arthritis / M-Csf / アデノウイルスベクタ / M-CSF / アデノウイルスベクター / 骨髄キメラ / 関節炎モデルマウス / 単球 / novel antoantogens / cDNA expression cloning analysis / Human IgG antibody / SCID mice / salivary and lacrimal glands biopsy tissue / Sjogren's syndrome (SS) / 新規自己抗原 / cDNA発現クローニング / ヒトIgG抗体 / SCIDマウス / 病巣涙腺・唾液腺 / シェーグレン症候群(SS) / antiphospholipid syndrome / scleroderma / immune thrombocytopenic purpura / immunotherapy / HLA / autoimmune disease / T cell / dendritic cell / 造血器腫瘍 / 抗腫瘍免疫 / 自己免疫性血小板減少症 / 強皮症 / 特発性血小板減少性紫斑病 / 抗リン脂質抗体症候群 / 免疫療法 / 主要組織適応抗原 / 自己免疫疾患 / T細胞 / 樹状細胞 / シンバスタチン / BMP受容体 / 血管内皮細胞 / 低酸素 / 肺動脈性高血圧症 / リウマチ学 / 多分化能 / 細胞接着 / 皮膚疾患 / 自己抗体 / カドヘリン / 天疱瘡 / モデルマウス / 免疫寛容 / 自己免疫 Less

Construction of a comprehensive pathological model reflecting the skin transcriptome of patients with systemic sclerosisPrincipal Investigator
- Principal Investigator
  
  桑名正隆
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nippon Medical School
Circulating monocytes in contributing to myocardial involvement of systemic sclerosisPrincipal Investigator
- Principal Investigator
  
  Kuwana Masataka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nippon Medical School
Identification of circulating monocyte subset contributing to pathogenesis of systemic sclerosisPrincipal Investigator
- Principal Investigator
  
  Kuwana Masataka
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nippon Medical School
Development of novel strategies for treating systemic sclerosis focusing on circulating monocytesPrincipal Investigator
- Principal Investigator
  
  KUWANA Masataka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nippon Medical School
Analysis of monocytes involved in joint destruction and joint repair in rheumatoid arthritis
- Principal Investigator
  
  SETA noriyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tokyo Dental College
  Keio University
Roles of bone marrow-derived cells in pathogenesis of pulmonary arterial hypertension associated with connective tissue diseasesPrincipal Investigator
- Principal Investigator
  
  KUWANA Masataka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
Analysis of monocytes involved in joint destruction and joint repair in rheumatoid arthritis
- Principal Investigator
  
  SETA Noriyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
A mechanism for hypoxia-induced pulmonary arterial hypertension
- Principal Investigator
  
  SATOH Takashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University
Analysis of pathogenesis of systemic sclerosis based on dysfunctional endothelial progenitor cells and its application to novel therapeutic interventionsPrincipal Investigator
- Principal Investigator
  
  KUWANA Masataka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
Examination of a role for circulating monocytes in pathogenesis of rheumatoid arthritis
- Principal Investigator
  
  SETA Noriyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
Role of donorderived fibroblasts in the pathogenic process of lacriimal gland chronic graft-versus-host disease
- Principal Investigator
  
  OGAWA Yoko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Elucidation of tolerance mechanism against peripheral target antigens in autoimmune diseases
- Principal Investigator
  
  AMAGAI Masayuki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Establishment of optimal tissue regenerating procedures using monocyte-derived multipotential cells for tissue regenerationPrincipal Investigator
- Principal Investigator
  
  KUWAMA Masataka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Keio University
ヒト組織移植免疫不全マウスを用いた線維化抑制療法の評価モデルの確立Principal Investigator
- Principal Investigator
  
  桑名正隆
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Keio University
Identification of novel autoantigens using human IgG in SCID mice implanted with lacrimal and salivary grands from patients with Sjogren's Syndrome
- Principal Investigator
  
  SAKURAI Toshiharu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
Gene expression profiling and evaluation of physiologic functions in monocyte-derived multipotential cellsPrincipal Investigator
- Principal Investigator
  
  KUWANA Masataka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Keio University
病因遺伝子解析結果に基づいたベーチェット病の病態解明の試みPrincipal Investigator
- Principal Investigator
  
  桑名正隆
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  内科学一般
- Research Institution
  Keio University
Analysis of Pathogenic Autoreactive T cells in Patients with Antiphospholipid Syndrome and its Application for Developing Specific Immune TherapiesPrincipal Investigator
- Principal Investigator
  
  KUWANA Masataka
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Keio University
強皮症病変皮膚の線維芽細胞における自己抗原の修飾の解析Principal Investigator
- Principal Investigator
  
  桑名正隆
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Keio University
全身性硬化症(強皮症)における自己抗体産生機序の解明Principal Investigator
- Principal Investigator
  
  桑名正隆
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Keio University
Selective Suppression of Pathogenic T Cell Responses Using Dendritic Cells
- Principal Investigator
  
  IKEDA Yasuo
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  内科学一般
- Research Institution
  Keio University
全身性硬化症におけるトポイソメラーゼIに対する自己免疫応答の解明-クラスIIHLAと抗原提示細胞の役割-Principal Investigator
- Principal Investigator
  
  桑名正隆
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Keio University

[Book] 全身性硬化症(強皮症).間質性肺疾患診療マニュアル2010
- Author(s)
  桑名正隆
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21390300
[Book] 強皮症.最新内科学
- Author(s)
  桑名正隆
- Publisher
  西村書店、東京(印刷中)
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Biomarker analysis from the phase 2b randomized placebo-controlled trial of riociguat in early diffuse cutaneous systemic sclerosis2024
- Author(s)
  Khanna D, Kramer F, Hofler J, Ghadessi M, Sandner P, Allanore Y, Denton CP, Kuwana M, et al
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 11 Pages: 3124-3134
- DOI
  10.1093/rheumatology/keae150
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07884
[Journal Article] Clinical worsening following discontinuation of tocilizumab in diffuse cutaneous systemic sclerosis: a single-centre experience in Japan2022
- Author(s)
  Isomura Y, Shirai Y, Kuwana M
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: - Issue: 11 Pages: 4491-4496
- DOI
  10.1093/rheumatology/keac136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08921, KAKENHI-PROJECT-20K08812
[Journal Article] Use of vonoprazan, a novel potassium-competitive acid blocker, for the treatment of proton pump inhibitor-refractory reflux esophagitis in patients with systemic sclerosis2022
- Author(s)
  Shirai Y, Kawami N, Iwakiri K, Kuwana M
- Journal Title
  
  J Scleroderma Relat Disord
  
  Volume: 7 Issue: 1 Pages: 57-61
- DOI
  10.1177/23971983211021747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08921, KAKENHI-PROJECT-20K08812
[Journal Article] Chest wall muscle atrophy as a contributory factor for forced vital capacity decline in systemic sclerosis-interstitial lung disease2021
- Author(s)
  Nawata T, Shirai Y, Suzuki M, and Kuwana M
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 60(1) Issue: 1 Pages: 250-255
- DOI
  10.1093/rheumatology/keaa322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Nintedanib in patients with systemic sclerosis-associated interstitial lung disease: subgroup analyses by autoantibody status and skin score.2021
- Author(s)
  Kuwana M, Allanore Y, Denton CP, Distler JHW, Steen VD, Khanna D, Matucci-Cerinic M, Mayes MD, Volkmann ER, Miede C, Gahlemann M, Quaresma Lic M, Alves M, and Distler O
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 74 Issue: 3 Pages: 518-526
- DOI
  10.1002/art.41965
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Primary systemic sclerosis heart involvement: a systematic literature review and preliminary consensus-based WSF/HFA definition2021
- Author(s)
  Bruni C, Kuwana M. (35人中27番目)
- Journal Title
  
  J. Scleroderma Relet. Disord
  
  Volume: 7 Issue: 1 Pages: 24-32
- DOI
  10.1177/23971983211053246
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Outcomes in patients with systemic sclerosis undergoing early versus delayed intervention with potential disease-modifying therapies2021
- Author(s)
  Yomono K and Kuwana M
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: - Issue: 9 Pages: 3677-3685
- DOI
  10.1093/rheumatology/keab931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Therapeutic approaches to systemic sclerosis: Recent approvals and future candidate therapies2021
- Author(s)
  Lescoat A, Roofeh D, Kuwana M, Lafyatis R, Allanore Y, and Khanna D
- Journal Title
  
  Clin. Rev. Allergy Immunol
  
  Volume: - Issue: 3 Pages: 239-261
- DOI
  10.1007/s12016-021-08891-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Clinical relevance of the serial measurement of Krebs von den Lungen-6 levels in patients with systemic sclerosis-associated interstitial lung disease2021
- Author(s)
  Shirai Y, Fukue R, Kaneko Y, Kuwana M
- Journal Title
  
  Diagnostics
  
  Volume: 11 Issue: 11 Pages: 2007-2007
- DOI
  10.3390/diagnostics11112007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08921, KAKENHI-PROJECT-20K08812
[Journal Article] Initial predictors of skin thickness progression in patients with diffuse cutaneous systemic sclerosis: results from a multicentre prospective cohort in Japan.2021
- Author(s)
  Kuwana M, Hasegawa M, Fukue R, Shirai Y, Ishikawa O, Endo H, Ogawa F, Goto D, Kawaguchi Y, Sato S, Ihn H, and Takehara K
- Journal Title
  
  Mod. Rheumatol
  
  Volume: 31(2) Issue: 2 Pages: 386-393
- DOI
  10.1080/14397595.2020.1784548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] A randomized, double-blind, placebo-controlled phase 3 study of lenabasum in diffuse cutaneous systemic sclerosis: RESOLVE-1 design and rationale2021
- Author(s)
  Spiera R, Khanna D, Kuwana M, Furst DE, Frech TM, Hummers L, Stevens W, Matucci-Cerinic M, Baron M, Distler O, Dgetluck N, Bloom BJ, Dinh Q, White B, and Denton CP
- Journal Title
  
  Clin. Exp. Rheumatol
  
  Volume: 131 Pages: 124-133
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Updates on genetics in systemic sclerosis2021
- Author(s)
  Ota Y, and Kuwana M
- Journal Title
  
  Inflamm. Regen
  
  Volume: 4 Issue: 1 Pages: 17-17
- DOI
  10.1186/s41232-021-00167-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Systemic sclerosis and the COVID-19 pandemic: World Scleroderma Foundation preliminary advice for patient management2020
- Author(s)
  Matucci-Cerinic M, Bruni C, Allanore Y, Clementi M, Dagna L, Damjanov N, De Paulis A, Denton CP, Distler O, Fox D, Furst DE, Khanna D, Krieg T, Kuwana M, Lee EB, Li, Pillai S, Wang Y, Zeng X, and Taliani G
- Journal Title
  
  Ann. Rheum. Dis
  
  Volume: 79(6) Issue: 6 Pages: 724-726
- DOI
  10.1136/annrheumdis-2020-217407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08812
[Journal Article] Endothelial cells and endothelial progenitor cells in the pathogenesis of systemic sclerosis2020
- Author(s)
  Ota Yuko、Kuwana Masataka
- Journal Title
  
  European Journal of Rheumatology
  
  Volume: 7 Issue: -3 Pages: 139-146
- DOI
  10.5152/eurjrheum.2019.19158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] Fos-related antigen-1 transgenic mouse as a model for systemic sclerosis: A potential role of M2 polarization2019
- Author(s)
  Yasuoka H, Yuen Yu Angela Tam, Okazaki Y, Tamura Y, Matsuo K, Carol Feghali-Bostwick, Takeuchi T, Kuwana M
- Journal Title
  
  J Scleroderma Relat Disord
  
  Volume: 4(2) Issue: 2 Pages: 137-148
- DOI
  10.1177/2397198319838140
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08183, KAKENHI-PROJECT-17K09989
[Journal Article] Progression of Interstitial Lung Disease in Systemic Sclerosis: The Importance of Pneumoproteins Krebs von den Lungen 6 and CCL182019
- Author(s)
  Volkmann Elizabeth R.、Tashkin Donald P.、Kuwana Masataka、et al
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 71 Issue: 12 Pages: 2059-2067
- DOI
  10.1002/art.41020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] Add-on tocilizumab versus conventional treatment for systemic sclerosis, and cytokine analysis to identify endotype to tocilizumab therapy2019
- Author(s)
  Shima Y, Kawaguchi Y, and Kuwana M
- Journal Title
  
  Mod. Rheumatol
  
  Volume: 29 Issue: 1 Pages: 134-139
- DOI
  10.1080/14397595.2018.1452178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] Fra-1 transgenic mouse as a model for systemic sclerosis: a potential role of M2 polarization2019
- Author(s)
  Yasuoka H, Tam YY, Okazaki Y, Tamura Y, Matsuo K, Feghali-Bostwick C, Takeuchi T, and Kuwana M
- Journal Title
  
  J. Scleroderma Relat. Disord
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] Performance of candidate serum biomarkers for systemic sclerosis-interstitial lung disease2019
- Author(s)
  Elhai M, Hoffmann-Vold AM, Pezet S, Cauvet A, Leblond A, Avouac J, Kuwana M, Molberg ø248; 248; 248;216;216;, and Allanore Y
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 0 Issue: 6 Pages: 0-0
- DOI
  10.1002/art.40815
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] KL-6 but not CCL-18 is a predictor of early progression in systemic sclerosis-related interstitial lung disease2018
- Author(s)
  Salazar GA, Kuwana M, Wu M, Estrada-Y-Martin RM, Ying J, Charles J, Mayes MD, and Assassi S
- Journal Title
  
  J. Rheumatol
  
  Volume: 45 Issue: 8 Pages: 1153-1158
- DOI
  10.3899/jrheum.170518
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] KL-6 but not CCL-18 is a predictor of early progression in systemic sclerosis related interstitial lung disease2018
- Author(s)
  335.Salazar GA, Kuwana M, Wu M, Estrada-Y-Martin R, Ying J, Charles J, Mayes MD and Assassi S
- Journal Title
  
  J. Rheumatol
  
  Volume: In press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] Pathogenesis of systemic sclerosis: recent insights of molecular and cellular mechanisms and therapeutic opportunities2017
- Author(s)
  Varga J, Trojanowska M, and Kuwana M
- Journal Title
  
  J. Scleroderma Relat. Disord
  
  Volume: 2 Issue: 3 Pages: 137-152
- DOI
  10.5301/jsrd.5000249
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Journal Article] 単球由来多能性細胞を用いた膠原病治療の可能性を探る2016
- Author(s)
  桑名正隆
- Journal Title
  
  分子リウマチ治療
  
  Volume: 258 Pages: 19-23
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] Recent updates in experimental protocols for endothelial cells.2016
- Author(s)
  Kahaleh B, Guiducci S, and Kuwana M
- Journal Title
  
  J. Scleroderma Rel. Dis
  
  Volume: 1 Pages: 257-265
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] Elevated serum Krebs von den Lungen-6 in early disease predicts subsequent deterioration of pulmonary function in patients with systemic sclerosis and interstitial lung disease2016
- Author(s)
  Kuwana M, Shirai Y, and Takeuchi T
- Journal Title
  
  J. Rheumatol.
  
  Volume: 43 Pages: 1835-1831
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] Tocilizumab is clinically, functionally, and radiographically effective and safe either with or without low-dose methotrexate in active rheumatoid arthritis patients with inadequate responses to DMARDs and/or TNF inhibitors: A single-center retrospective cohort study (KEIO-TCZ study) at week 52.2015
- Author(s)
  22.Izumi K, Kaneko Y, Yasuoka H, Seta N, Kameda H, Kuwana M, and Takeuchi T.
- Journal Title
  
  Modern Rheumatology
  
  Volume: 25 Issue: 1 Pages: 31-7
- DOI
  10.3109/14397595.2014.897793
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591455
[Journal Article] Elevated pentraxin 3 in systemic sclerosis: associations with vascular manifestations and defective vasculogenesis.2015
- Author(s)
  Shirai Y, Okazaki Y, Inoue Y, Tamura Y, Yasuoka H, Takeuchi T, and Kuwana M.
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 67 Issue: 2 Pages: 498-507
- DOI
  10.1002/art.38953
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] Rapid initiation of intravenous epoprostenol infusion is the favored option in patients with advanced pulmonary arterial hypertension2015
- Author(s)
  Kimura M, Tamura Y, Takei M, Yamamoto T, One T, Kuwana M, Fukuda K, and Satoh T
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 4 Pages: e0121894-e0121894
- DOI
  10.1371/journal.pone.0121894
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] Oral vasopressin receptor antagonist tolvaptan in right heart failure due to pulmonary hypertension2015
- Author(s)
  Tamura Y, Kimura M, Takei M, Ono T, Kuwana M, Satoh T, Fukuda K, and Humbert M
- Journal Title
  
  Eur. Respir. J
  
  Volume: 46 Issue: 1 Pages: 283-286
- DOI
  10.1183/09031936.00044915
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] Clinical and immunological predictors of scleroderma renal crisis in Japanese systemic sclerosis patients with anti-RNA polymerase III antibodies.2015
- Author(s)
  Hamaguchi Y, Kodera M, Matsushita T, Usuda T, Kuwana M, Takehara K, and Fujimoto M
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 67 Issue: 4 Pages: 1045-1052
- DOI
  10.1002/art.38994
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461471, KAKENHI-PROJECT-26461680, KAKENHI-PROJECT-25461686
[Journal Article] 強皮症の新たな治療概念2015
- Author(s)
  桑名正隆
- Journal Title
  
  臨床リウマチ
  
  Volume: 27 Pages: 281-287
- NAID
  130005141285
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] 強皮症性混合型肺高血圧症に対する病態評価と治療のポイント2015
- Author(s)
  桑名正隆
- Journal Title
  
  内科
  
  Volume: 117 Pages: 449-454
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] 免疫抑制薬の臨床応用実践論2015
- Author(s)
  桑名正隆
- Journal Title
  
  炎症と免疫
  
  Volume: 23 Pages: 90-95
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] 強皮症重症例に対する治療2015
- Author(s)
  桑名正隆
- Journal Title
  
  分子リウマチ治療
  
  Volume: 8 Pages: 50-53
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] 強皮症の病態と最新治療2014
- Author(s)
  桑名正隆
- Journal Title
  
  Medicina
  
  Volume: 51 Pages: 2409-2413
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement.2014
- Author(s)
  Kaji K, Fertig N, Medsger TA Jr, Satoh T, Hoshino K, Hamaguchi Y, Hasegawa M, Lucas M, Schnure A, Ogawa F, Sato S, Takehara K, Fujimoto M, Kuwana M.
- Journal Title
  
  Arthritis Care Res
  
  Volume: 66 Issue: 4 Pages: 575-84
- DOI
  10.1002/acr.22163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-26461471
[Journal Article] Impaired in vivo neovascularization capacity of endothelial progenitor cells in patients with systemic sclerosis.2014
- Author(s)
  Kuwana M, and Okazaki Y.
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 66 Issue: 5 Pages: 1300-1305
- DOI
  10.1002/art.38326
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461471
[Journal Article] A single nucleotide polymorphism of TRAF1 predicts the clinical response to anti-TNF treatment in Japanese patients with rheumatoid arthritis.2013
- Author(s)
  Nishimoto T, Seta N, Anan R, Yamamoto T, Kaneko Y, Takeuchi T, and Kuwana M.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591455
[Journal Article] Potential involvement of human circulating CD14^+ monocytes in tissuerepair and regeneration2012
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 32 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Quantification of circulating endothelial progenitor cells in systemic sclerosis : a direct comparison of protocols2012
- Author(s)
  Kuwana M, Okazaki Y
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 71 Issue: 4 Pages: 617-620
- DOI
  10.1136/annrheumdis-2011-200713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Circulating anti-double-stranded DNA antibody-secreting cells in patients with systemic lupus erythematosus: a novel biomarker for disease activity2012
- Author(s)
  Hanaoka H, Okazaki Y, Satoh T, Kaneko Y, Yasuoka H, Seta N, and Kuwana M
- Journal Title
  
  Lupus
  
  Volume: 21 Issue: 12 Pages: 1284-1293
- DOI
  10.1177/0961203312453191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591455
[Journal Article] Intracranial transplantation of monocyte-derived multipotential cells enhances recovery after ischemic stroke in rats2012
- Author(s)
  Hattori H, Suzuki S, Okazaki Y, Suzuki N, Kuwana M
- Journal Title
  
  J Neurosci Res
  
  Volume: 90(2) Pages: 479-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Potential Involvement of Human Circulating CD14^+Monocytes in Tissue Repair and Regeneration2012
- Author(s)
  Seta N and Kuwana M
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 32(1) Pages: 1-7
- NAID
  130004482286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591270
[Journal Article] Quantification of circulating endothelial progenitor cells in systemic sclerosis : a direct comparison of protocols2012
- Author(s)
  Kuwana M, Okazaki Y
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 71(4) Pages: 617-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Fibronectin binding is required for acquisition of mesenchymal/endothelial differentiation potential in human circulating monocytes.2012
- Author(s)
  Seta N, Okazaki Y, Izumi K, Miyazaki H, Kato T, and Kuwana M
- Journal Title
  
  Clin. Exp. Immunol.
  
  Volume: 1 Pages: 1-9
- DOI
  10.1155/2012/820827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591455
[Journal Article] Potential Involvement of Human Circulating CD14^+ Monocytes in Tissue Repair and Regeneration2012
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: VOL.32 Pages: 1-7
- NAID
  130004482286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591270
[Journal Article] Association of Hepatocyte Growth Factor promoter polymorphism with severity of interstitial lung disease in Japanese patients with systemic sclerosis2011
- Author(s)
  Hoshino K, Satoh T, Kawaguchi Y, Kuwana M
- Journal Title
  
  Arthritis & Rheumatism
  
  Volume: 63 Issue: 8 Pages: 2465-2472
- DOI
  10.1002/art.30415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Effect of bosentan on systemic sclerosis-associated interstitial lung disease ineligible for cyclophosphamide therapy : a prospective open-label study2011
- Author(s)
  Furuya Y, Kuwana M
- Journal Title
  
  The Journal of Rheumatology
  
  Volume: 38 Issue: 10 Pages: 2186-2192
- DOI
  10.3899/jrheum.110499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Association of Hepatocyte Growth Factor promoter polymorphism with severity of interstitial lung disease in Japanese patients with systemic sclerosis2011
- Author(s)
  Hoshino K, Satoh T, Kawaguchi Y, Kuwana M
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63(8) Pages: 2465-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Derivation of multipotent progenitors from human circulating CD14+monocytes2010
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  Exp Hematol
  
  Volume: 38(7) Pages: 557-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Derivation of multipotent progenitors from human circulating CD14+monocytes2010
- Author(s)
  Seta N and Kuwana M
- Journal Title
  
  Exp. Hematol
  
  Volume: 38(7) Pages: 556-583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591270
[Journal Article] Mobilization of endothelial progenitor cells by intravenous cyclophosphamide in patients with systemic sclerosis : potential association with efficacy for interstitial lung disease2010
- Author(s)
  Furuya Y, Okazaki Y, Kaji K, Sato S, Takehara K, Kuwana M
- Journal Title
  
  Rheumatology
  
  Volume: 49(12) Pages: 2375-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] 話題;強皮症の早期診断2010
- Author(s)
  桑名正隆
- Journal Title
  
  リウマチ科
  
  Volume: 44 Pages: 464-472
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Interleukin-6 as a potential therapeutic target for pulmonary arterial hypertension2010
- Author(s)
  Furuya Y, Satoh T, Kuwana M
- Journal Title
  
  Int J Rheumatol
  
  Volume: 2010 Pages: 720305-720305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] 膠原病-新たな治療戦略;膠原病診療の実際:全身性硬化症2010
- Author(s)
  桑名正隆
- Journal Title
  
  臨床と研究
  
  Volume: 87(9) Pages: 1209-13
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Enhanced angiogenic potency of monocytic endothelial progenitor cells in patients with systemic sclerosis2010
- Author(s)
  Yamaguchi Y, Okazaki Y, Seta N, Satoh T, Takahashi K, Ikezawa Z, and Kuwana M
- Journal Title
  
  Arthritis Res. Ther
  
  Volume: 12(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591270
[Journal Article] Derivation of multipotent progenitors from human circulating CD14+ monocytes.2010
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  Experimental Hematology
  
  Volume: VOL.38 Pages: 556-583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591270
[Journal Article] Enhanced angiogenic potency of monocytic endothelial progenitor cells in patients with systemic sclerosis2010
- Author(s)
  Yamaguchi Y, Okazaki Y, Seta N, Satoh T, Takahashi K, Ikezawa Z, Kuwana M
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Enhanced angiogenic potency of monocytic endothelial progenitor cells in patients with systemic sclerosis2010
- Author(s)
  Yamaguchi Y, Okazaki Y, Seta N, Satoh T, Takahashi K, Ikezawa Z, Kuwana M
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 12(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] Enhanced angiogenic potency of monocytic endothelial progenitor cells in patients with systemic sclerosis.2010
- Author(s)
  Yamaguchi Y, Okazaki Y, Seta N, Satoh T, Takahashi K, Ikezawa Z, Kuwana M.
- Journal Title
  
  Arthritis Research & Theraphy
  
  Volume: VOL.12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591270
[Journal Article] A single helper T cell clone is sufficient to commit polyclonal naive B cells to produce pathogenic IgG in experimental pemphigus vulgaris2009
- Author(s)
  Takahashi H, Kuwana M, Amagai M
- Journal Title
  
  J Immunol 182
  
  Pages: 1740-1745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109012
[Journal Article] RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermato myositis : association with rapidly progressive interstitial lung disease2009
- Author(s)
  Sato S, Hoshino K, Satoh T, Fujita T, Kawakami Y, Fujita T, Kuwana M
- Journal Title
  
  Arthritis & Rheumatism 60
  
  Pages: 2193-2200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390300
[Journal Article] A single helper T cell clone is sufficient to commit polyclonal naive B cells to produce pathogenic IgG in experimental pemphigus vulgaris2009
- Author(s)
  Takahashi H, Kuwana M, Amagai M
- Journal Title
  
  J Immunol 182(3)
  
  Pages: 1740-1745
- Data Source
  KAKENHI-PROJECT-17109012
[Journal Article] Novel system evaluating in vivo pathogenicity of desmoglein 3-reactive T cell clones using murine pemphigus vulgaris.2008
- Author(s)
  Takahashi H, Amagai M, Nishikawa T, Fujii Y, Kawakami Y, Kuwana M
- Journal Title
  
  J Immunol 181(2)
  
  Pages: 1526-1535
- Data Source
  KAKENHI-PROJECT-17109012
[Journal Article] Human circulating monocytes can express receptor activator of nuclear factor-kB ligand and differentiate into functional osteoclasts without exogenous stimulation2008
- Author(s)
  Seta N, Okazaki Y, Kuwana M
- Journal Title
  
  Immunology and Cell Biology 86
  
  Pages: 453-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390275
[Journal Article] Novel system evaluating in vivo pathogenicity of desmoglein 3-reactive T cell clones using murine pemphigus vulgaris2008
- Author(s)
  Takahashi H, Amagai M, Nishikawa T, Fujii Y, Kawakami Y, Kuwana M
- Journal Title
  
  J Immunol 181
  
  Pages: 1526-1535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109012
[Journal Article] A CD40-CD154 interaction in tissue fibrosis2008
- Author(s)
  Kawai M, Masuda A, Kuwana M
- Journal Title
  
  Arthritis & Rheumatism 58
  
  Pages: 3562-3573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390275
[Journal Article] A CD40-CD154 interaction in tissue fibrosis2008
- Author(s)
  Kawai M, Masuda A, Kuwana M.
- Journal Title
  
  Arthritis Rheum 58(11)
  
  Pages: 3562-3573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390275
[Journal Article] Estrogen receptor gene polymorphisms in Japanese patients with systemic sclerosis2008
- Author(s)
  1. Hoshi M, Yasuoka H, Kuwana M.
- Journal Title
  
  Clin. Exp. Rheumatol 26(5)
  
  Pages: 914-917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390275
[Journal Article] Human circulating monocytes can express receptor activator of nuclear factor-αB ligand and differentiate into functional osteoclasts without exogenous stimulation2008
- Author(s)
  Seta N, Okazaki Y, Kuwana M.
- Journal Title
  
  Immunol. Cell Biol 86(5)
  
  Pages: 453-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390275
[Journal Article] Estrogen receptor gene polymorphisms in Japanese patients with systemic sclerosis2008
- Author(s)
  Hoshi M, Yasuoka H, Kuwana M
- Journal Title
  
  Clinical Experimental Rheumatology 26
  
  Pages: 914-917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390275
[Journal Article] Human circulating monocytes as multipotential progenitors2007
- Author(s)
  Seta, N, Kuwana, M
- Journal Title
  
  The Keio Journal of Medicine 56
  
  Pages: 41-47
- NAID
  130000103945
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591125
[Journal Article] Human circulating monocytes as multipotential progenitors2007
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  The Keio Journal of Medicine 56
  
  Pages: 41-47
- NAID
  130000103945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591125
[Journal Article] T helper type 2-biased natural killer cell phenotype in patients with pemphigus vulgaris.2007
- Author(s)
  Takahashi H, Amagai M, Tanikawa A, Suzuki S, Ikeda Y, Nishikawa T, Kawakami Y, Kuwana M
- Journal Title
  
  J Invest Dermatol 127
  
  Pages: 324-330
- Data Source
  KAKENHI-PROJECT-17109012
[Journal Article] Human circulating monocytes as multipotential progenitors2007
- Author(s)
  Seta N, Kuwana M.
- Journal Title
  
  Keio J. Med. 56(2)
  
  Pages: 41-47
- NAID
  130000103945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390275
[Journal Article] Human circulating monocytes as multipotential progenitors2007
- Author(s)
  Seta N and Kuwana M
- Journal Title
  
  The Keio Journal of Medicine 56
  
  Pages: 41-47
- NAID
  130000103945
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591125
[Journal Article] Role of heat shock protein 47, a collagen-binding chaperone, in lacrimal gland pathology in patients with cGVHD2007
- Author(s)
  Ogawa, Y, Kawakami, Y, Kuwana, M., et. al.
- Journal Title
  
  Invest Ophthalmol Vis Sci 48
  
  Pages: 1079-1086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591932
[Journal Article] Role of heat shock protein 47, a collagen-binding chaperone, in lacrimal gland pathology in patients with cGVHD2007
- Author(s)
  Ogawa Y, Razzaque MS, Kameyama K, Hasegawa G, Shimmura S, Kawai M, Okamoto S, Ikeda Y, Tsubota K, Kawakami Y, Kuwana
- Journal Title
  
  Invest Ophthalmol Vis Sci 48.3
  
  Pages: 1079-1086
- Data Source
  KAKENHI-PROJECT-18591932
[Journal Article] T helper type 2-biased natural killer cell phenotype in patients with pemphigus vulgaris2007
- Author(s)
  Takahashi H, Amagai M, Tanikawa A, Suzuki S, Ikeda Y, Nishikawa T, Kawakami Y, Kuwana M
- Journal Title
  
  J Invest Dermatol 127・2
  
  Pages: 324-330
- Data Source
  KAKENHI-PROJECT-17109012
[Journal Article] Endothelial differentiation potential of human monocyte-derived multipotential cells2006
- Author(s)
  Kuwana M, Okazaki Y, et al.
- Journal Title
  
  Stem Cells 24・12
  
  Pages: 2733-2743
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Increase in circulating endothelial precursors by atorvastatin in patients with systemic sclerosis2006
- Author(s)
  Kuwana M, Kaburaki J, et al.
- Journal Title
  
  Arthritis ＆ Rheumatism 54・6
  
  Pages: 1946-1951
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Neurogenic potential of progenitors derived from human circulating CD14^+ monocytes2006
- Author(s)
  Kodama H, Kuwana M, et al.
- Journal Title
  
  Immunology and Cell Biology 84・2
  
  Pages: 209-217
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Increase in circulating endothelial precursors by atorvastatin in patients with systemic sclerosis2006
- Author(s)
  Kuwana M, Kaburaki J et al.
- Journal Title
  
  Arthritis ＆ Rheumatism 54-6
  
  Pages: 1946-1951
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Neurogenic potential of progenitors derived from human circulating CD 14^+ monocytes2006
- Author(s)
  Kodama H, Kuwana M et al.
- Journal Title
  
  Immunology and Cell Biology 84-2
  
  Pages: 209-217
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Endothelial differentiation potential of human monocyte-derived multipotential cells2006
- Author(s)
  Kuwana M, Okazaki Y et al.
- Journal Title
  
  Stem Cells 24-12
  
  Pages: 2733-2743
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Donor fibroblast chimerism in the lacrimal gland of human chronic graft-versus-host disease2005
- Author(s)
  Ogawa Y, Kuwana M, et al.
- Journal Title
  
  Investigative Ophthalmology and Visual Science 46・12
  
  Pages: 4519-4527
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] Interleukin-10 genotypes are associated with systemic sclerosis and influence disease-associated autoimmune responses2005
- Author(s)
  Hudson LL, Kuwana M, et al.
- Journal Title
  
  Genes and Immunity 6・3
  
  Pages: 274-278
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] Cardiomyogenic potential of mesenchymal progenitors derived from human circulating CD 14^+ monocytes2005
- Author(s)
  Kodama H, Kuwana M et al.
- Journal Title
  
  Stem Cells and Development 14-6
  
  Pages: 676-686
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Lack of circulating autoantibodies to bone morphogenetic protein receptor-II or activin receptor-like kinase 1 in mixed connective tissue disease patients with pulmonary arterial hypertension2005
- Author(s)
  Satoh T, Kuwana M, et al.
- Journal Title
  
  Rheumatology 44・2
  
  Pages: 192-196
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] Cardiomyogenic potential of mesenchymal progenitors derived from human circulating CD14^+ monocytes2005
- Author(s)
  Kodama H, Kuwana M, et al.
- Journal Title
  
  Stem Cells and Development 14・6
  
  Pages: 676-686
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Enzyme-linked immunosorbent assay for detection of anti-RNA polymerase III antibody : analytical accuracy and clinical associations in systemic sclerosis2005
- Author(s)
  Kuwana M, et al.
- Journal Title
  
  Arthritis and Rheumatism 52・8
  
  Pages: 2425-2432
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] Mortality in systemic sclerosis : an international meta-analysis of individual patient data2005
- Author(s)
  Ioannidis JPA, Kuwana M, et al.
- Journal Title
  
  Am J Med 118・1
  
  Pages: 2-10
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] Defective vasculogenesis in systemic sclerosis2004
- Author(s)
  Kuwana M, et al.
- Journal Title
  
  Lancet 364・9434
  
  Pages: 603-610
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] Defective vasculogenesis in systemic sclerosis2004
- Author(s)
  Kuwana M, et al.
- Journal Title
  
  Lancet 364・9434
  
  Pages: 603-610
- Data Source
  KAKENHI-PROJECT-15390307
[Journal Article] 強皮症患者由来線維芽細胞で発現される新規自己抗原2004
- Author(s)
  安岡秀剛, 桑名正隆
- Journal Title
  
  臨床免疫 42・2
  
  Pages: 214-217
- NAID
  40006398254
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] The effect of a single injection of humanized anti-CD 154 monclonal antibody on the platelet-specific autoimmune response in patients with immune thrombocytopenic purpura2004
- Author(s)
  Kuwana M, et al.
- Journal Title
  
  Blood 103
  
  Pages: 1229-1236
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390307
[Journal Article] Defective vasculogenesis in systemic sclerosis2004
- Author(s)
  Kuwana M, et al.
- Journal Title
  
  Lancet 364
  
  Pages: 603-610
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390307
[Journal Article] Human circulating CD14^+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation2003
- Author(s)
  Kuwana M, et al.
- Journal Title
  
  Journal of Leukocyte Biology 74
  
  Pages: 833-845
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390307
[Journal Article] A novel protein highly expressed in testis is overexpressed in systemic sclerosis fibroblasts and targeted by autoantibodies2003
- Author(s)
  Yasuoka H, Kuwana M, et al.
- Journal Title
  
  Journal of Immunology 171
  
  Pages: 6883-6890
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390307
[Journal Article] Interleukin-10 genotypes are associated with systemic sclerosis and influence disease-associated autoimmune responses
- Author(s)
  Hudson LL, Kuwana M, et al.
- Journal Title
  
  Genes Immun (印刷中)
- Data Source
  KAKENHI-PROJECT-16659267
[Journal Article] Human circulating monocytes as multipotential progenitors
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  The Keio Journal of Medicine (In press)
- NAID
  130000103945
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Human circulating monocytes as multipotential progenitors
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  The Keio Journal of Medicine (In press)
- NAID
  130000103945
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Journal Article] Human circulating monocytes as multipotential progenitors
- Author(s)
  Seta N, Kuwana M
- Journal Title
  
  The Keio Journal of Medicine (In press)
- NAID
  130000103945
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Patent] 単球由来多能性細胞(MOMC)の効率的な作製法2007
- Inventor(s)
  桑名正隆、加藤尚志、瀬田範行、宮崎洋
- Industrial Property Rights Holder
  学校法人慶應義塾
- Filing Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-19390275
[Patent] 単球由来多能性細胞(MOMC)の効率的な作製法2007
- Inventor(s)
  桑名正隆、加藤尚志、瀬田範行、宮崎洋
- Industrial Property Rights Holder
  学校法人慶應義塾
- Filing Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-19390275
[Patent] CD40-CD154シグナル阻害による抗線維化剤2006
- Inventor(s)
  桑名正隆
- Industrial Property Rights Holder
  慶應義塾
- Filing Date
  2006-01-12
- Data Source
  KAKENHI-PROJECT-16659267
[Patent] 単球由来多能性細胞MOMC2005
- Inventor(s)
  桑名正隆, 小玉博明
- Industrial Property Rights Holder
  慶應義塾
- Filing Date
  2005-08-05
- Acquisition Date
  2007-03-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390284
[Presentation] New treatment of SSc associated ILD2023
- Author(s)
  Kuwana M
- Organizer
  The 44th Korean College of Rheumatology Annual Scientific Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07884
[Presentation] Improving the Outcome of Systemic Sclerosis2023
- Author(s)
  Kuwana M
- Organizer
  International Conference of Chinese Rheumatologists 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07884
[Presentation] Effect of Nintedanib on KL-6 in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease in the SENSCIS Trial2021
- Author(s)
  Assassi S, Christopher P Denton, Cutolo M, Tracy R Luckhardt, Diefenbach C, Ittrich C, Alves M, Kuwana M on behalf of the SENSCIS trial investigators
- Organizer
  ACR Convergence2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Presentation] Outcomes of Dose-Reduction or Discontinuation of Tocilizumab in Patients with Early Diffuse Cutaneous Systemic Sclerosis2021
- Author(s)
  Isomura Y, Yamasaki Y, Shirai Y, Kuwana M
- Organizer
  Annual European Congress of Rheumatology EULAR2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Presentation] Management of pulmonary arterial hypertension and interstitial lung disease associated with systemic sclerosis2021
- Author(s)
  Kuwana M
- Organizer
  23st Asia Pacific League of Associations for Rheumatology Congress. APLAR2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Presentation] Early Intervention with Immunomodulators Leads to Better Outcomes in Patients with Systemic Sclerosis.2021
- Author(s)
  Yomono K, and Kuwana M
- Organizer
  ACR Convergence2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Presentation] Effects of Nintedanib on Patient-Reported Outcomes in Japanese Patients with Progressive Fibrosing Interstitial Lung Diseases: Sub-Analysis of INBUILD2020
- Author(s)
  Kuwana M, Inoue Y, Inase N, Makino S, Takizawa A, Takenouchi K, Rohr K, Schlenker-Herceg R, Takeuchi T
- Organizer
  APLAR2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08812
[Presentation] Current problems and future direction of management of systemic sclerosis2019
- Author(s)
  Kuwana M
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] 強皮症の病態関連遺伝子2019
- Author(s)
  桑名正隆
- Organizer
  第40回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] Are we on the verge of cracking the nut in systemic sclerosis?2019
- Author(s)
  Kuwana M
- Organizer
  21st Asia Pacific League of Associations for Rheumatology Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] Utility of risk stratification in predicting outcomes of initial monotherapy versus combination therapy in pulmonary arterial hypertension associated with connective tissue disease: a post-hoc analysis of the AMBITION study2019
- Author(s)
  Kuwana M, Blair C, Langley J, Takahashi T, Coghlan G
- Organizer
  EULAR2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] Management of systemic sclerosis: current status and future directions2018
- Author(s)
  Kuwana M
- Organizer
  The 38th Korean College of Rheumatology Annual Scientific Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] Interstitial lung disease associated with systemic sclerosis: current and future approach to the management2018
- Author(s)
  Kuwana M
- Organizer
  20th Asia Pacific League of Associations for Rheumatology Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] Biomarker in SSc-associated interstitial lung disease2018
- Author(s)
  Kuwana M
- Organizer
  The 9th Symposium of International Network of Scleroderma Clinical Care and Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] 全身性強皮症2018
- Author(s)
  桑名　正隆
- Organizer
  第39回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] New Autoantibodies, organ involvement and disease progression2018
- Author(s)
  Kuwana M
- Organizer
  5th Systemic Sclerosis World Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09989
[Presentation] Predictors of digital ulcer in SSc: endothelial progenitor cells and circulating biomarkers.2016
- Author(s)
  Kuwana M
- Organizer
  18th Asia Pacific League of Associations for Rheumatology Congress.
- Place of Presentation
  Shanghai
- Year and Date
  2016-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] An Increased Circulating Level of Periostin in Patients with Systemic Sclerosis: Associations with Functional Impairment in Various Affected Organs Display combined fields only if separate fields don't exist2016
- Author(s)
  Yamaguchi Y, Shirai Y, Ono J, Kawaguchi Y, Izuhara K, Kuwana M and Aihara M
- Organizer
  80th Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  Washington, DC
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] M2-Shifted Mice Recapitulate Dermal and Pulmonary Remodeling2016
- Author(s)
  Yasuoka H, Tam Y. Y, Okazaki Y, Tamura Y, Matsuo K, Takeuchi T, Kuwana M
- Organizer
  4th Systemic Sclerosis World Congress
- Place of Presentation
  Lisbon/PORTUGAL
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] Efficacy and Safety of Tocilizumab in Patients with Systemic Sclerosis: Experiences in a Routine Clinical Setting2016
- Author(s)
  Shirai Y, Takeuchi T, Kuwana M
- Organizer
  4th Systemic Sclerosis World Congress
- Place of Presentation
  Lisbon/PORTUGAL
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] Parameters That Predict Worsening of Skin Thickness in Patients with Early Diffuse Cutaneous Systemic Sclerosis2015
- Author(s)
  Kuwana M, Hasegawa, M Shirai Y, Ishikawa O, Endo H, Ogawa F, Goto D, Sato S, Ihn H, Kawaguchi Y and Takehara K
- Organizer
  79th Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  San Francisco/USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] Clinical Utility of Serial KL-6 Measurement in Interstitial Lung Disease Associated with Systemic Sclerosis2015
- Author(s)
  Shirai Y, Takeuchi T and Kuwana M
- Organizer
  79th Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  San Francisco/USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] 強皮症に対するIL-6阻害療法2015
- Author(s)
  桑名正隆
- Organizer
  第59回日本リウマチ学会総会
- Place of Presentation
  名古屋/日本
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] Angiogenesis and vasculogenesis in systemic sclerosis-review and gaps in the evidence2012
- Author(s)
  Kuwana M
- Organizer
  2nd Systemic Sclerosis World Congress(Madrid)
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] Organ involvement in early SSc2011
- Author(s)
  Kuwana M
- Organizer
  4th International Systemic Sclerosis Forum-Combating Morbidity and Mortality
- Place of Presentation
  Barcelona
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] Impaired in vivo neovascularization capacity of endothelial progenitor cells in patients with systemic sclerosis2011
- Author(s)
  Kuwana M, Okazaki Y, Yasuoka H, Takeuchi T
- Organizer
  The 75th Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  McCormick Place West (Chicago)
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] カレントシンポジウム;膠原病の診療最前線;強皮症2011
- Author(s)
  桑名正隆
- Organizer
  第55回日本リウマチ学会総会
- Place of Presentation
  神戸
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] Impaired in vivo neovascularization capacity of endothelial progenitor cells in patients with systemic sclerosis2011
- Author(s)
  Kuwana M, Okazaki Y, Yasuoka H, Takeuchi T
- Organizer
  The 75th Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  Chicago
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] 強皮症患者の抗トポイソメラーゼI抗体産生はいつからみられるか?2010
- Author(s)
  桑名正隆、鏑木淳一
- Organizer
  第54回日本リウマチ学会総会
- Place of Presentation
  神戸ポートピアホテル(神戸市)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] Clinical and immunological characteristics of Japanese patients with connective tissue disease and pulmonary arterial hypertension2010
- Author(s)
  Shirai Y, Yasuoka H, Takeuchi T, Satoh T, Kuwana M
- Organizer
  1st Systemic Sclerosis World Congress
- Place of Presentation
  Florence
- Year and Date
  2010-02-13
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] Quantification of circulating endothelial progenitor cells verification of the EUSTAR recommendations.2010
- Author(s)
  Okazaki Y, Satoh T, Yasuoka H, Kuwana M
- Organizer
  1st Systemic Sclerosis World Congress
- Place of Presentation
  Florence
- Year and Date
  2010-02-13
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] Upregulated expression of versican in monocytes from patients with systemic sclerosis : role in amplification of MCP-1 activity at site of fibrosis.2010
- Author(s)
  Yasuoka H, Masuda A, Yamaguchi Y, Satoh T, Kuwana M
- Organizer
  1st Systemic Sclerosis World Congress
- Place of Presentation
  Florence
- Year and Date
  2010-02-12
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] The gene polymorphism within hepatocyte growth factor promoter controls progression of systemic sclerosis-associated interstitial lung disease.2010
- Author(s)
  Satoh T, Hoshino K, Kuwana M
- Organizer
  1st Systemic Sclerosis World Congress
- Place of Presentation
  Florence
- Year and Date
  2010-02-13
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] 強皮症患者におけるVEGFおよびHIF-1αの一塩基多型解析2010
- Author(s)
  佐藤隆司、岡崎有佳、白井悠一郎、安岡秀剛、竹内勤、桑名正隆
- Organizer
  第54回日本リウマチ学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] 強皮症における循環血管内皮前駆細胞(EPC)数の再検討2010
- Author(s)
  岡崎有佳、佐藤隆司、安岡秀剛、竹内勤、桑名正隆
- Organizer
  第54回日本リウマチ学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] 未治療関節リウマチ患者由来末梢血単核球のフェノタイプと血漿中液性因子の解析2010
- Author(s)
  瀬田範行、金子祐子、安岡秀剛、佐藤隆司、竹内勤、桑名正隆
- Organizer
  第54回日本リウマチ学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591270
[Presentation] 未治療関節リウマチ患者由来末梢血単核球のフェノタイプと血漿中液性因子の解析2010
- Author(s)
  瀬田範行、金子祐子、安岡秀剛、佐藤隆司、竹内勤、桑名正隆
- Organizer
  第54回日本リウマチ学会総会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21591270
[Presentation] マウス関節炎モデルにおける骨髄由来細胞の役割2009
- Author(s)
  瀬田範行、海江田信二郎、岡田保典、桑名正隆
- Organizer
  第53回日本リウマチ学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591270
[Presentation] 膠原病関連肺高血圧症2009
- Author(s)
  桑名正隆
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田ビューホテル(秋田県)
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-21390300
[Presentation] 強皮症末梢血単球のフェノタイプ解析第12回強皮症研究会2009
- Author(s)
  増田絢子、安岡秀剛、山口由衣、岡崎有佳、佐藤隆司、桑名正隆
- Organizer
  第12回強皮症研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-17
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] 強皮症におけるHGF及びその受容体の一塩基多型解析2008
- Author(s)
  星野香菜、佐藤隆司、桑名正隆
- Organizer
  第52回日本リウマチ学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-04-22
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Fibrogenic gene expression profiles in circulating monocytes from patients with systemic sclerosis (SSc)2008
- Author(s)
  増田絢子、安岡秀剛、山口由衣、佐藤隆司、桑名正隆
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] 強皮症末梢血単球のフェノタイプ解析2008
- Author(s)
  増田絢子、山口由衣、岡崎有佳、佐藤隆司、桑名正隆
- Organizer
  第52回日本リウマチ学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-04-22
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] 強皮症における単球系血管内皮前駆細胞(MEP)の解析2008
- Author(s)
  桑名正隆、山口由衣、増田絢子、岡崎有佳、高橋一夫、池澤善郎
- Organizer
  第11回強皮症研究会
- Place of Presentation
  東京
- Year and Date
  2008-01-19
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] 強皮症におけるHGFおよびその受容体の一塩基多型(SNP)解析2008
- Author(s)
  星野香菜、佐藤隆司、桑名正隆
- Organizer
  第11回強皮症研究会
- Place of Presentation
  東京
- Year and Date
  2008-01-19
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Insufficient repair as a mechanism for scleroderma vasculopathy2008
- Author(s)
  Kuwana M
- Organizer
  13th Congress of the Asia Pacific League of Associations for Rheumatology
- Place of Presentation
  Yokohama
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Circulating endothelial cell progenitors in scleroderma2008
- Author(s)
  Kuwana M
- Organizer
  The 10th International Workshop for Scleroderma Research
- Place of Presentation
  Cambridge
- Year and Date
  2008-08-05
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Single desmoglein 3-reactive CD4+ T cell clones activate polyclonal naive B cells and promote the production of pathogenic IgG in experimental pemphigus vulgaris2008
- Author(s)
  Takahashi H, Kuwana M, Amagai M
- Organizer
  The International Investigative Dermatology 2008
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-17109012
[Presentation] Single desmoglein 3-reactive CD4+ T cell clones activate polyolonalnaive B cells and promote the production of pathogenic IgG inexperimental pemphigus vulgaris2008
- Author(s)
  Takahashi H, Kuwana M, Amagai M
- Organizer
  The International Investigative Dermatology 2008
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-17109012
[Presentation] Hepatocyte growth factor promoter gene polymorphism controls severity of interstitial lung disease in patients with systemic sclerosis2008
- Author(s)
  Hoshino K, Satoh T, Kuwana M
- Organizer
  The 72nd Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  San Francisco
- Year and Date
  2008-10-27
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Deficient vascular repair as a mechanism for scleroderma vascular disease2007
- Author(s)
  Kuwana M
- Organizer
  Carwile LeRoy Memorial International Workshop on Scleroderma(Professor E.)
- Place of Presentation
  Tokyo
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Hepatocyte growth factor gene polymorphism can predict end-stage lung disease in patients with systemic sclerosis2007
- Author(s)
  Hoshino K, Satoh T, Kuwana M
- Organizer
  Carwile LeRoy Memorial International Workshop on Scleroderma(Professor E.)
- Place of Presentation
  Tokyo
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] A critical role of the CD40-CD154 interaction in fibroblast activation2007
- Author(s)
  Kuwana M, Kawai M, Furuya Y
- Organizer
  Carwile LeRoy Memorial International Workshop on Scleroderma(Professor E.)
- Place of Presentation
  Tokyo
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Paradoxical increase in monocytic progenitors for endothelial cells in patients with systemic sclerosis2007
- Author(s)
  Yamaguchi Y, Okazaki Y, Seta N, Satoh T, Takahashi K, Ikezawa Z, Kuwana M
- Organizer
  The 71th Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  Boston
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19390275
[Presentation] Characterization of desmoglein 3-reactive helper T cells involved in pathogenic IgG production in a mouse model for pemphigus vulgaris2006
- Author(s)
  Takahashi H, Amagai M, Nishikawa T, Kawakami Y, Kuwana M
- Organizer
  The 67th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-17109012
[Presentation] Elevated Pentraxin 3 in Patients with Systemic Sclerosis: Associations with Vascular Manifestations and Defective Vasculogenesis.
- Author(s)
  Shirai Y, Okazaki Y, Inoue Y, Tamura Y, Yasuoka H, Takeuchi T, and Kuwana M
- Organizer
  The 78th Annual Scientific Meeting of American College of Rheumatology
- Place of Presentation
  Boston/USA
- Year and Date
  2014-11-14 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26461471
[Presentation] Treat to Target（T2T）に基づいた関節リウマチに対するインフリキシマブの投与間隔短縮の実践
- Author(s)
  53.倉沢隆彦、鈴木勝也、花岡洋成、金子祐子、安岡秀剛、瀬田範行、桑名正隆、亀田秀人、平形道人、竹内勤
- Organizer
  第58回日本リウマチ学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24591455

1. SETA Noriyuki (40338372)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. IKEDA Yasuo (00110883)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SATOH Takashi (90407114)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
4. KAWAKAMI Yutaka (50161287)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. AMAGAI Masayuki (90212563)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. KOYASU Shigeo (90153684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ISHIKO Akira (10202988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KANEKO Yuko (60317112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. INOUE Yumiko (60348638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FURUYA Yoshiaki (30424154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. ASAHI Atsuko (50348265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Shigeaki (50276242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. INOKO Hidetoshi (10101932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. INOUE Takafumi (10262081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SAKURAI Toshiharu (20101933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAJIMA Tatsuo (40095633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KISHI Kazuo (40224919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ISHIDA Akaru (80212885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKAHASHI Hayato (40398615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. OGAWA Yoko (30160774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. 河合正孝 (50296662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAMURA Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. SHIRAI Yuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
24. 藤本学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuwana Masataka 桑名 正隆

KUWANA Masataka 桑名 正隆

桑名 正隆 クワナ マサタカ

Research Projects

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Construction of a comprehensive pathological model reflecting the skin transcriptome of patients with systemic sclerosisPrincipal Investigator

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Circulating monocytes in contributing to myocardial involvement of systemic sclerosisPrincipal Investigator

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Identification of circulating monocyte subset contributing to pathogenesis of systemic sclerosisPrincipal Investigator

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Development of novel strategies for treating systemic sclerosis focusing on circulating monocytesPrincipal Investigator

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Roles of bone marrow-derived cells in pathogenesis of pulmonary arterial hypertension associated with connective tissue diseasesPrincipal Investigator

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Analysis of pathogenesis of systemic sclerosis based on dysfunctional endothelial progenitor cells and its application to novel therapeutic interventionsPrincipal Investigator

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Establishment of optimal tissue regenerating procedures using monocyte-derived multipotential cells for tissue regenerationPrincipal Investigator

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ヒト組織移植免疫不全マウスを用いた線維化抑制療法の評価モデルの確立Principal Investigator

Principal Investigator

Kuwana Masataka 桑名正隆

KUWANA Masataka 桑名正隆

桑名正隆クワナマサタカ