Hazama Shoichi 硲彰一

… Alternative Names

HAZAMA Shoichi 硲彰一

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Researcher Number	50253159
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2021 – 2023: 山口大学, 医学部, 特別医学研究員 2021: 山口大学, 医学部, 教授(連携講座) 2017 – 2020: 山口大学, 医学部, 教授(寄附講座等) 2007 – 2011: Yamaguchi University, 大学院・医学系研究科, 准教授 2002 – 2005: Yamaguchi University Hospital, Assistant Professor, 医学部附属病院, 講師 1993 – 2001: 山口大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / Digestive surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 56030:Urology-related / Biological Sciences
Keywords	Principal Investigator gene therapy / ネオアンチゲン / ペプチド / chemokine / cytokine / GM-CSF / IL-18 / IL-15 / UGT1A1 / イリノテカン … More / 遺伝子多型 / 化学療法 / 大腸癌 / non-coding RNA / 消化器癌 / 癌 / マルチ抗原 / 多種類（マルチ）HLA結合ペプチド / がん幹細胞関連抗原 / Calreticulin / Cathepsin B / MUC1 / 免疫療法 / がん幹細胞 / 膵癌 / MIP-1alpha / Vaccination / mouse / inter lerkin-18 / immunotherapy / MIP-1a / EGFR / P13K / cetuximab / Cetuximab / UGT1As / Irinotecan / PI3K / BRAF / KRAS / セツキシマブ / ^6 / ^28 / 6 / 28 / UGT1Ai / 毒性 / mou / Meth-A / Oene Therapy / raccination / Tumor immumity / interleukin-15 / 免疫染色 / RT-PCR / iCIl-1ra(細胞内局在型) / sIL-1ra(分泌型) / 胃癌細胞株 / 胃癌 … More Except Principal Investigator 膵癌 / nm23-H1 / オルガノイド / YAP / 大腸癌 / 化学療法 / MUC1 / 免疫組織染色 / メカノホメオスターシス / 大腸癌肝転移 / 癌 / 免疫チェックポイント / がん免疫 / 肝転移 / miRNA / Gemcitabine / ペプチドワクチン / Chemotherapy / マイクロアレイ / cell therapy / 樹状細胞 / 細胞療法 / CTL / NM23-H1遺伝子 / pancreatic cancer / prognosis / IL-2 / 免疫療法 / 肝細胞癌 / 遺伝子解析 / CTL療法 / 予後 / CDDP / 食道癌 / 腸内細菌叢 / 人工腸管 / 力学恒常性 / がんオルガノイド / イメージング・マスサイトメトリー / メカノホメオスターシス / YAPレポーターマウス / magnetic tweezers法 / CODEX法 / 磁気ピンセット法 / PhenoCycler / がん免疫微小環境 / YAPの活性化 / YAP活性化 / がん発症・進展 / 遺伝子多型 / 個別化医療 / 副作用診断チップ / ゲノム網羅的解析 / 進行大腸癌 / FOLFOXIRI療法 / 同定 / RNA-seq / LCM / 大腸がん / TCRレパト / TCRレパトア / CyTOF / マスサイトメトリー / 腫瘍浸潤リンパ球 / CTC / 血中循環腫瘍細胞 / 膵臓がん / 膵がん / 遺伝子チップ / アルゴリズム / 治療効果予測 / 泌尿器癌 / ミスマッチ修復蛋白 / 消化管内マイクロバイオーム / 口腔内マイクロバイオーム / ミスマッチ修復遺伝子 / マイクロサテライト不安定性 / 腎細胞癌 / 尿路上皮癌 / 抗PD-1抗体 / 固形がん / がんペプチド療法 / 癌局所微小環境 / 負の免疫応答 / バイオマーカー / 免疫チェックポイント阻害剤 / ペプチドワクチン療法 / 力学特性 / 免疫チェックポイント療法 / リンパ節 / microRNA / 癌微小環境 / 癌間質 / Peptide vaccination / Immunotherapy / Pancreatic cancer / postoperative recurrence / vaccine therapy / Pancreatic Cancer / 手術 / 再発防止 / ワクチン療法 / Immunohistochemical staining / Microarray / Intrahepatic recurrence / Hepatocellular carcinoma / RT-PCR / テロメラーゼ活性 / 免疫染色 / 肝再発 / 肝内再発 / nm23-H1遺伝子 / 肝癌 / dendritic cell / cancer vaccine therapy / cancer-related peptide / ペプチド療法 / 癌ワクチン療法 / 癌ペプチド / cisplatin / chemosensitivity / chemotherapy / Esophageal cancer / 制癌剤感受性 / 転移抑制遺伝子 / 感受性 / 制癌剤 / postoperative administration / adoptive immunotherapy / liver metastasis / cytotoxic T lymphocyte / MUC1特異的CTL / MUC1抗原 / 肝転移防止 / 術後投与 / 養子免疫療法 / cytotoxic T-lymphocyte / apoptosis / liver regeneration / intraarterial infusion / immunotherapy / hepatectomy / hepatocellular carcinoma / リンパ球サブセット / 細胞障害性T細胞 / 予後改善 / アポトーシス / 肝再生 / 肝動注 / 肝切除 / 臨床効果 / DC療法 / アンチセンス / 薬剤感受性 / VP-16 / S-Fu Less

A mini-organ culture system with cancer immune microenvironment recapitulating in vivo
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
Identification of tumor-specific antigens to construct the novel combination immunotherapyPrincipal Investigator
- Principal Investigator
  
  Hazama Shoichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Can Anti-EGFR Antibodies Turn Colorectal Cancer into Hot Tumors?
- Principal Investigator
  
  Tomochika Shinobu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Identification and elucidation of liver metastasis-associated miRNAs in primary colorectal cancer
- Principal Investigator
  
  XU MING
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Development of an in vitro diagnosis of adverse effects of FOLFOXIRI therapy for colorectal cancer
- Principal Investigator
  
  Suzuki Nobuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
がん発症・進展過程におけるYAPの活性化の機械的制御機構の解明
- Principal Investigator
  
  田尾嘉誉
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Development of new immunotherapy for metastatic pancreatic cancer by applying organoids derived from circulating tumor cells in blood.
- Principal Investigator
  
  Tanabe Tsuyoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Yamaguchi University
Analysis of CD4+FOXP3+ cells infiltrating colorectal tumors using CyTOF and their relationship to prognosis
- Principal Investigator
  
  YOSHIDA Shin
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Creation of lyph node organoids enabling mechanical control of immunity
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
MSI related predictive biomarkers of response to immune checkpoint inhibitors for patients with metastatic urological cancers
- Principal Investigator
  
  Yamamoto Yoshiaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
Novel immunotherapy for pancreatic cancer by the multi-HLA binding peptides derived from cancer stemness molecules.Principal Investigator
- Principal Investigator
  
  Hazama Shoichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Identification for biomarkers in cancer peptide vaccine therapy with immune checkpoint inhibitors
- Principal Investigator
  
  Suzuki Nobuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Analysis of microRNA in cancer microenvironment involved in colorectal liver metastasis
- Principal Investigator
  
  IIDA Michihisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Novel strategy for prediction of toxicity and efficacy of chemotherapy for patients with metastatic colorectal cancer.Principal Investigator
- Principal Investigator
  
  HAZAMA Shoichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
The polymorphisms can predict the adverse effects of chemotherapy in patients with colorectal cancerPrincipal Investigator
- Principal Investigator
  
  HAZAMA Shoichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Combination therapy with immunotherapy and chemotherapy for pancreatic cancer. -Aim at the standardization of clinical trial for immuno-chemotherapy-
- Principal Investigator
  
  YAMAMOTO Koutaro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
膵癌に対するMUC1刺激樹状細胞療法の臨床研究―樹状細胞マイクロアレイ解析を含めて―
- Principal Investigator
  
  岡正朗
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
Immunotherapy for prevention of postoperative recurrence in pancreatic cancer using cell therapy and vaccine therapy
- Principal Investigator
  
  OKA Masaaki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Immunotherapy using cytotoxic T cell and peptide vaccine for pancreatic cancer
- Principal Investigator
  
  OKA Masaaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Relation between nm23-H1 expression and effect of chemotherapy for hepatocellular carcinoma
- Principal Investigator
  
  OKA Masaaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Targeting chemotherapy with NM 23-H1 for carcinoma of the esophagus
- Principal Investigator
  
  TANGOKU Akira
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
食道癌のNM23-H1の発現に基づいた化学療法の開発
- Principal Investigator
  
  岡正朗
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Yamaguchi University
Immunogene therapy for the gostrointestinal malignancies using tumor cells engineered to secrete cytokines and chemokinesPrincipal Investigator
- Principal Investigator
  
  HAZAMA Shoich
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
新しい癌ワクチン療法におけるinterleuk in-15遺伝子導入療法の有用性Principal Investigator
- Principal Investigator
  
  硲彰一
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Adoptive immunotherapy using MUC1 specific cytotoxic T lymphocytes for pancreatic cancer
- Principal Investigator
  
  OKA Masaaki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
IL-1R antaqonist発現による胃癌悪性度評価と遺伝子療法への応用Principal Investigator
- Principal Investigator
  
  硲彰一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
New Immunotherapy for hepatocellular carcinoma after hepatectomy
- Principal Investigator
  
  OKA Masaaki
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University

[Book] 消化器外科レビュー20052005
- Author(s)
  硲彰一
- Total Pages
  249
- Publisher
  株式会社総合医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390397
[Journal Article] High serum proteinase-3 levels predict poor progression-free survival and lower efficacy of bevacizumab in metastatic colorectal cancer2024
- Author(s)
  Furuya Kei、Nakajima Masao、Tsunedomi Ryouichi、Nakagami Yuki、Xu Ming、Matsui Hiroto、Tokumitsu Yukio、Shindo Yoshitaro、Watanabe Yusaku、Tomochika Shinobu、Maeda Noriko、Iida Michihisa、Suzuki Nobuaki、Takeda Shigeru、Hazama Shoichi、Ioka Tatsuya、Hoshii Yoshinobu、Ueno Tomio、Nagano Hiroaki
- Journal Title
  
  BMC Cancer
  
  Volume: 24 Issue: 1 Pages: 165-165
- DOI
  10.1186/s12885-024-11924-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08874, KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756, KAKENHI-PROJECT-21K16448
[Journal Article] IL-6 levels correlate with prognosis and immunosuppressive stromal cells in patients with colorectal cancer2023
- Author(s)
  Yamamoto Tsunenori, Tunedomi Ryouichi, Nakajima Masao, Suzuki Nobuaki, Yoshida Shin, Tomochika Shinobu, Nakagami Yuki, Xu Ming, Hazama Shoichi, Tanabe Tsuyoshi, Ioka Tatsuya, Hoshii Yoshinobu, Kiyota Akifumi, Takizawa Hitoshi, Kawakami Yutaka, Ueno Tomio, Nagano Hiroaki, et. al.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09079
[Journal Article] Anti-VEGF and Anti-EGFR Antibody Therapy on T-Cell Infiltration and TCR Variation in Metastatic Colorectal Cancer2023
- Author(s)
  XU MING、TSUNEDOMI RYOUICHI、KIYOTANI KAZUMA、TOMOCHIKA SHINOBU、FURUYA KEI、NAKAJIMA MASAO、MATSUI HIROTO、TOKUMITSU YUKIO、SHINDO YOSHITARO、YOSHIDA SHIN、IIDA MICHIHISA、SUZUKI NOBUAKI、TAKEDA SHIGERU、IOKA TATSUYA、HAZAMA SHOICHI、NAGANO HIROAKI
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 2 Pages: 613-620
- DOI
  10.21873/anticanres.16197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756
[Journal Article] Development of multiple AI pipeline that predict NAC response of breast cancer using H&E-stained tissues.2023
- Author(s)
  Bin Shen, Akira Saito, Ai Ueda, Koji Fujita, Mikihiro Hashimoto, Masaharu Kobayashi, Aashiq H. Mirza, Hans Peter Graf, Eric Cosatto, Shoichi Hazama, Hiroaki Nagano, Toshitaka Nagao, Eiichi Sato, Esther Cheng, Syed AF Hoda, Takashi Ishikawa, Masahiko Kuroda.
- Journal Title
  
  J Pathol Clin Res
  
  Volume: 9 Issue: 3 Pages: 182-194
- DOI
  10.1002/cjp2.314
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-23K06432, KAKENHI-PROJECT-21K08711
[Journal Article] Phase I study of a novel therapeutic vaccine as perioperative treatment for patients with surgically resectable hepatocellular carcinoma: The YCP02 trial2023
- Author(s)
  Nakajima M, Hazama S, Tokumitsu Y, Shindo Y, Matsui H, Matsukuma S, Nakagami Y, Tamada K, Udaka K, Sakamoto M, Saito A, Kouki Y, Uematsu T, Ming Xu, Iida M, Tsunedomi R, Suzuki N, Takeda S, Ioka T, Doi S, Nagano H
- Journal Title
  
  Hepatol Res.
  
  Volume: - Issue: 7 Pages: 649-660
- DOI
  10.1111/hepr.13900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04808, KAKENHI-PROJECT-20K17618, KAKENHI-PROJECT-22K16513, KAKENHI-PROJECT-21K08711, KAKENHI-PROJECT-21K08756
[Journal Article] IL-6 Levels Correlate with Prognosis and Immunosuppressive Stromal Cells in Patients with Colorectal Cancer2023
- Author(s)
  Yamamoto Tsunenori、Tsunedomi Ryouichi、Nakajima Masao、Suzuki Nobuaki、Yoshida Shin、Tomochika Shinobu、Xu Ming、Nakagami Yuki、Matsui Hiroto、Tokumitsu Yukio、Shindo Yoshitaro、Watanabe Yusaku、Iida Michihisa、Takeda Shigeru、Hazama Shoichi、Tanabe Tsuyoshi、Ioka Tatsuya、Hoshii Yoshinobu、Kiyota Akifumi、et al.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 30 Issue: 8 Pages: 5267-5277
- DOI
  10.1245/s10434-023-13527-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08850, KAKENHI-PROJECT-22K08874, KAKENHI-PROJECT-21K08711, KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756, KAKENHI-PROJECT-21K16448
[Journal Article] Serum CCL7 Is a Novel Prognostic Biomarker of Metastatic Colorectal Cancer2022
- Author(s)
  CHIDIMATSU HIKARI、TSUNEDOMI RYOUICHI、NAKAGAMI YUKI、XU MING、NAKAJIMA MASAO、NAKASHIMA-NAKASUGA CHIYO、TOMOCHIKA SHINOBU、et al
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 1 Pages: 105-114
- DOI
  10.21873/anticanres.16139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756, KAKENHI-PROJECT-22K08874
[Journal Article] CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule2022
- Author(s)
  Nakagami Yuki、Hazama Shoichi、Suzuki Nobuaki、Yoshida Shin、Tomochika Shinobu、et al
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 1071-1071
- DOI
  10.1186/s12885-022-10181-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-22K08874, KAKENHI-PROJECT-20H03534
[Journal Article] Association between a single nucleotide polymorphism in the <i>R3HCC1</i> gene and irinotecan toxicity2022
- Author(s)
  Kanesada Kou、Tsunedomi Ryouichi、Hazama Shoichi、Ogihara Hiroyuki、Hamamoto Yoshihiko、Shindo Yoshitaro、Matsui Hiroto、Tokumitsu Yukio、Yoshida Shin、Iida Michihisa、Suzuki Nobuaki、Takeda Shigeru、Ioka Tatsuya、Nagano Hiroaki
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 4 Pages: 4294-4305
- DOI
  10.1002/cam4.5299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08799, KAKENHI-PROJECT-22K08849
[Journal Article] Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids2021
- Author(s)
  Elbadawy Mohamed、Hayashi Kimika、Ayame Hiromi、Ishihara Yusuke、Abugomaa Amira、Shibutani Makoto、Hayashi Shim-Mo、Hazama Shoichi、Takenouchi Hiroko、Nakajima Masao、Tsunedomi Ryouichi、Suzuki Nobuaki、Nagano Hiroaki、Shinohara Yuta、Kaneda Masahiro、Yamawaki Hideyuki、Usui Tatsuya、Sasaki Kazuaki
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 142 Pages: 112043-112043
- DOI
  10.1016/j.biopha.2021.112043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-21K08711
[Journal Article] Transcript-targeted analysis reveals isoform alterations and double-hop fusions in breast cancer2021
- Author(s)
  Namba Shinichi、Ueno Toshihide、Kojima Shinya、Kobayashi Kenya、Kawase Katsushige、Tanaka Yosuke、Inoue Satoshi、Kishigami Fumishi、Kawashima Shusuke、Maeda Noriko、Ogawa Tomoko、Hazama Shoichi、Togashi Yosuke、Ando Mizuo、Shiraishi Yuichi、Mano Hiroyuki、Kawazu Masahito
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1320-1320
- DOI
  10.1038/s42003-021-02833-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21K08711, KAKENHI-PROJECT-21K12117
[Journal Article] Pancreatic Cancer Stem-Like Cells With High Calreticulin Expression Associated With Immune Surveillance2021
- Author(s)
  Fujiwara Yasuhiro、Tsunedomi Ryouichi、Yoshimura Kiyoshi、Matsukuma Satoshi、Fujiwara Nobuyuki、Nishiyama Mitsuo、Kanekiyo Shinsuke、Matsui Hiroto、Shindo Yoshitaro、Tokumitsu Yukio、Yoshida Shin、Iida Michihisa、Suzuki Nobuaki、Takeda Shigeru、Ioka Tatsuya、Hazama Shoichi、Nagano Hiroaki
- Journal Title
  
  Pancreas
  
  Volume: 50 Issue: 3 Pages: 405-413
- DOI
  10.1097/mpa.0000000000001772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07320, KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-20K08956, KAKENHI-PROJECT-20K17619, KAKENHI-PROJECT-20K17655, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K16364, KAKENHI-PROJECT-20K17620
[Journal Article] Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer2020
- Author(s)
  Yamada Kensuke、Hazama Shoichi、Suzuki Nobuaki、Xu Ming、Nakagami Yuki、Fujiwara Nobuyuki、Tsunedomi Ryouichi、Yoshida Shin、Tomochika Shinobu、Matsukuma Satoshi、Matsui Hiroto、Tokumitsu Yukio、Kanekiyo Shinsuke、Shindo Yoshitaro、Watanabe Yusaku、Iida Michihisa、Takeda Shigeru、Ioka Tatsuya、Ueno Tomio、et al.
- Journal Title
  
  Oncology Letters
  
  Volume: 21 Issue: 1 Pages: 1-1
- DOI
  10.3892/ol.2020.12271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-20K17619, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K16364, KAKENHI-PROJECT-20H03534
[Journal Article] Cathepsin B is highly expressed in pancreatic cancer stem-like cells and is associated with patients' surgical outcomes2020
- Author(s)
  Fujimoto Takuya、Tsunedomi Ryouichi、Matsukuma Satoshi、Yoshimura Kiyoshi、Oga Atsunori、Fujiwara Nobuyuki、Fujiwara Yasuhiro、Matsui Hiroto、Shindo Yoshitaro、Tokumitsu Yukio、Suzuki Nobuaki、Kobayashi Shogo、Hazama Shoichi、Eguchi Hidetoshi、Nagano Hiroaki
- Journal Title
  
  Oncology Letters
  
  Volume: 21 Issue: 1 Pages: 1-1
- DOI
  10.3892/ol.2020.12291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-20K17655, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K16364
[Journal Article] Clinical implications of cancer stem cells in digestive cancers: acquisition of stemness and prognostic impact.2020
- Author(s)
  Tsunedomi R、Yoshimura K、Suzuki N、Hazama S、Nagano H
- Journal Title
  
  Surgery Today
  
  Volume: - Issue: 12 Pages: 1560-1577
- DOI
  10.1007/s00595-020-01968-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K08646
[Journal Article] A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial.2020
- Author(s)
  Masao;Nakajima, Shoichi, Hazama; Koji;Tamada. Nobuaki;Suzuki.Hiroaki;Nagano
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 5 Issue: 8 Pages: 5-10
- DOI
  10.1007/s00262-020-02518-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08681, KAKENHI-PROJECT-16H02474, KAKENHI-PROJECT-19K07775, KAKENHI-PROJECT-20K17618, KAKENHI-PROJECT-20K17619, KAKENHI-PROJECT-20K17620, KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-18K08646
[Journal Article] Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial2020
- Author(s)
  Hiroto Matsui、Hazama Shoichi、Nakajima Masao、Xu Ming、Matsukuma Satoshi、Tokumitsu Yukio、Shindo Yoshitaro、Tomochika Shinobu、Yoshida Shin、Iida Michihisa、Suzuki Nobuaki、Takeda Shigeru、Yoshino Shigefumi、Ueno Tomio、Oka Masaaki、Nagano Hiroaki
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 70 Issue: 4 Pages: 945-957
- DOI
  10.1007/s00262-020-02737-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17620, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-21K08711, KAKENHI-PROJECT-20K17618, KAKENHI-PROJECT-20K17655
[Journal Article] Identification of a Promiscuous Epitope Peptide Derived From HSP70.2019
- Author(s)
  Matsui H, Hazama S, Tamada K, Udaka K, Irie A, Nishimura Y, Miyakawa T, Doi S, Nakajima M, Kanekiyo S, Tokumitsu Y, Shindo Y, Tomochika S, Yoshida S, Iida M, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Nagano H.
- Journal Title
  
  J Immunother.
  
  Volume: 42 Pages: 244-250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08618
[Journal Article] Identification of a Promiscuous Epitope Peptide Derived From HSP70.2019
- Author(s)
  Matsui H, Hazama S, Tamada K, Udaka K, Irie A, Nishimura Y, Miyakawa T, Doi S, Nakajima M, Kanekiyo S, Tokumitsu Y, Shindo Y, Tomochika S, Yoshida S, Iida M, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Nagano H
- Journal Title
  
  J Immunother
  
  Volume: 42 Issue: 7 Pages: 244-250
- DOI
  10.1097/cji.0000000000000274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08008, KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-18K08681, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-16H02474, KAKENHI-PROJECT-19K07775
[Journal Article] Novel Biomarkers for Personalized Cancer Immunotherapy.2019
- Author(s)
  Shindo Y, Hazama S, Tsunedomi R, Suzuki N, Nagano H.
- Journal Title
  
  Cancers (Basel).
  
  Volume: 121 Issue: 9 Pages: 983-984
- DOI
  10.3390/cancers11091223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-15H05791
[Journal Article] Overexpression of miR221 and miR222 in the cancer stroma is associated with malignant potential in colorectal cancer2018
- Author(s)
  Iida Michihisa、Hazama Shoichi、Tsunedomi Ryouichi、Tanaka Hironori、Takenouchi Hiroko、Kanekiyo Shinsuke、Tokumitsu Yukio、Tomochika Shinobu、Tokuhisa Yoshihiro、Sakamoto Kazuhiko、Suzuki Nobuaki、Takeda Shigeru、Ueno Tomio、Yamamoto Shigeru、Yoshino Shigefumi、Fujita Koji、Kuroda Masahiko、Nagano Hiroaki
- Journal Title
  
  Oncology Reports
  
  Volume: 40 Pages: 1621-1631
- DOI
  10.3892/or.2018.6575
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10635, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-17H04067, KAKENHI-PROJECT-16K10574, KAKENHI-PROJECT-17K16558
[Journal Article] IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides2018
- Author(s)
  Kanekiyo S, Hazama S, Takenouchi H, Nakajima M, Shindo Y, Matsui H, Tokumitsu Y, Tomochika S, Tsunedomi R, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Okuno K, Udaka K, Kawakami Y, Matsueda S, Ito K, Nagano H.
- Journal Title
  
  Oncology Reports
  
  Volume: 39 Pages: 2385-2392
- DOI
  10.3892/or.2018.6288
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-16K10574
[Journal Article] Combination treatment of advanced pancreatic cancer using novel vaccine and traditional therapies2018
- Author(s)
  Matsui H、Hazama S、Shindo Y、Nagano H
- Journal Title
  
  Expert Review of Anticancer Therapy
  
  Volume: 18 Issue: 12 Pages: 1205-1217
- DOI
  10.1080/14737140.2018.1531707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K08646
[Journal Article] Worldwide consortium-based validation of Immunoscore for the classification of colon cancer.2018
- Author(s)
  Pages F, Mlecnik B, Xu M, Kawakami Y, Galon J, et al.
- Journal Title
  
  Lancet
  
  Volume: 391(10135) Issue: 10135 Pages: 2128-2139
- DOI
  10.1016/s0140-6736(18)30789-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-17H01540
[Journal Article] Metastatic ability and the epithelial-mesenchymal transition in induced cancer stem-like hepatoma cells2018
- Author(s)
  Nishiyama M、Tsunedomi R、Yoshimura K、Hashimoto Ni、Matsukuma S、Ogihara H、Kanekiyo S、Iida M、Sakamoto K、Suzuki N、Takeda S、Yamamoto S、Yoshino S、Ueno T、Hamamoto Y、Hazama S、Nagano H
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 4 Pages: 1101-1109
- DOI
  10.1111/cas.13527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-16H05420, KAKENHI-PROJECT-16K10574
[Journal Article] Current status of immunotherapy against gastrointestinal cancers and its biomarkers: Perspective for precision immunotherapy2018
- Author(s)
  Hazama S、Tamada K、Yamaguchi Y、Kawakami Y、Nagano H
- Journal Title
  
  Annals of Gastroenterological Surgery
  
  Volume: 2 Issue: 4 Pages: 289-303
- DOI
  10.1002/ags3.12180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-16H02474
[Journal Article] Cediranib in combination with mFOLFOX6 in Japanese patients with mCRC2012
- Author(s)
  Kato T, Muro K, Hazama S, et al
- Journal Title
  
  Ann Oncol
  
  Volume: 23 Pages: 933-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Impact of chemotherapy for colorectal cancer on regulatory T-cells and tumor immunity2011
- Author(s)
  Maeda K, Hazama S, Tokuno K, Kan S, Maeda Y, Watanabe Y, Kamei R, Shindo Y, Maeda N, Yoshimura K, Yoshino S, Oka M
- Journal Title
  
  Anticancer Res
  
  Volume: 31(12): 4569-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Possible involvement of Wnt11 in colorectal cancer progression2011
- Author(s)
  ishioka M, Ueno K, Hazama S, et al
- Journal Title
  
  Mol Carcinog
  
  Volume: 10 Issue: 3 Pages: 207-217
- DOI
  10.1002/mc.21845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725, KAKENHI-PROJECT-23240129
[Journal Article] Cediranib in combination with mFOLFOX6 in Japanese patients with metastatic colorectal cancer : results from the randomised phase II part of a phase I/ II study2011
- Author(s)
  Kato T, Muro K, Yamaguchi K, Bando H, Hazama S, Amagai K, Baba H, Denda T, Shi X, Fukase K, Sakamoto J, Mishima H
- Journal Title
  
  Ann Oncol
  
  Volume: 23(4): 933-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Importance and practice of UGT1A1 polymorphisms2011
- Author(s)
  Hazama S, Oka M
- Journal Title
  
  Nihon Rinsho
  
  Volume: 69Suppl3 : 351-4
- NAID
  40018805551
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Prospective phase II study of FOLFIRI for mCRC in Japan, including the analysis of UGT1A1 28/ 6 polymorphisms2011
- Author(s)
  Okuyama Y, Hazama S, Nozawa H, Kobayashi M, Takahashi K, Fujikawa K, Kato T, Nagata N, Kimura H, Oba K, Sakamoto J, Mishima H
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 41(4): 477-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Impact of chemotherapy for CRC on regulatory T-cells and tumor immunity2011
- Author(s)
  Maeda K, Hazama S, Tokuno K, et al
- Journal Title
  
  Anticancer Res
  
  Volume: 31 Pages: 4569-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1*28 polymorphism2010
- Author(s)
  Hazama s, et al.
- Journal Title
  
  Cancer Sciense 101
  
  Pages: 722-727
- NAID
  10026589707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] The importance of evaluation of DNA amplificability in KRAS mutation testing with dideoxy sequencing using formalin-fixed and paraffin-embedded colorectal cancer tissues2010
- Author(s)
  Okayama N, Nishioka M, Hazama S, Sakai K, Suehiro Y, Maekawa M, Sakamoto J, Iwamoto S, Kato T, Mishima H, Oka M, Hinoda Y
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 41(2): 165-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1^* 28 polymorphism2009
- Author(s)
  Hazama S, Nagashima A, Kondo H, Yoshida S, Shimizu R, Araki A, Yoshino S, Okayama N, Hinoda Y, Oka M
- Journal Title
  
  Cancer Sci
  
  Volume: 101(3): 722-7
- NAID
  10026589707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells2009
- Author(s)
  Ueno K, Hazama S, Mitomori S, Nishioka M, Suehiro Y, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y
- Journal Title
  
  Br J Cancer
  
  Volume: 101(8): 1374-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591725
[Journal Article] UGT1A1 *6 is a predictive marker of severe neutropenia for metastatic CRC patients received FOLFIRI in JAPAN2008
- Author(s)
  S. Hazama, Y. Okuyama, T. Kato, K. Takahashi, H. Nozawa, N. Okayama, Y. Hinoda, M. Oka, J. Sakamoto, H. Mishima
- Journal Title
  
  Annals of Oncology 19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] CPT-11 (Irinotecan) Gan To Kagaku Ryoho2008
- Author(s)
  Hazama S, Oka M
- Journal Title
  
  35 182
  
  Pages: 182-184
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] 抗癌剤効果・副作用予測法の現況-CPT-11(Irinotecan)2008
- Author(s)
  硲彰一, 他
- Journal Title
  
  癌と化学療法 35
  
  Pages: 182-184
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] UGT1A1 *6 IS A PREDICTIVE MARKER OF SEVERE NEUTROPENIA FOR METASTATIC CRC PATIENTS RECEIVED FOLFIRI IN JAPAN2008
- Author(s)
  Hazama S, et al.
- Journal Title
  
  Annals of Oncology 19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] 切除不能・再発大腸癌に対するスタンダード化学療法われわれが行っているsequential chemotherapyの工夫2008
- Author(s)
  硲彰一, 長島淳, 近藤浩史, 飯田通久, 吉田晋, 徳久善弘, 蘓村秀明, 友近忍, 岡正朗
- Journal Title
  
  癌の臨床 54
  
  Pages: 741-745
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] 切除不能・再発大腸癌に対するスタンダード化学療法われわれが行っているsequential chemotherapyの工夫2008
- Author(s)
  硲彰一, 他
- Journal Title
  
  癌の臨床 54
  
  Pages: 741-745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] 特集:抗癌剤効果・副作用予測法の現況;CPT-11(Irinotecan)2007
- Author(s)
  硲彰一、他
- Journal Title
  
  癌と化学療法 35
  
  Pages: 182-184
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] UGT1As polymorphisms predict toxicity in colorectal cancer patients treated with different recommended doses of irinotecan oriented by UGT1A1^*28 polymorphism based on previous phase I study.2007
- Author(s)
  S Hazama, et. al.
- Journal Title
  
  Journal of Clinical Oncology 25
  
  Pages: 14511-14511
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] UGT1As polymorphisms predict toxicity in colorectal cancer patients treated with different recommended doses of irinotecan oriented by UGT1A1*28 polymorphism based on previous phase I study2007
- Author(s)
  S. Hazama, H. Kondo, S. Yoshida, R. Shimizu, H. Ozasa, T. Yamamoto, A. Araki, S. Yoshino, N. Okayama, Y. Hinoda, M. Oka
- Journal Title
  
  Journal of Clinical Oncology 25
  
  Pages: 14511-14511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591545
[Journal Article] Cancer Immunotherapy2005
- Author(s)
  Hazama S, et al.
- Journal Title
  
  Review of Digestive Surgery
  
  Pages: 249-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390397
[Patent] 医薬組成物2019
- Inventor(s)
  土肥　俊、瀬川美秀、玉田耕治、永野浩昭、硲　彰一
- Industrial Property Rights Holder
  サイトリミック株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-214479
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K08618
[Patent] 薬剤の作用・副作用予測システムとそのプログラム2008
- Inventor(s)
  硲彰一、他
- Industrial Property Rights Holder
  硲彰一、他
- Filing Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19591545
[Patent] 薬剤の作用・副作用予測システムとそのプログラム2008
- Inventor(s)
  硲彰一, 他
- Industrial Property Rights Holder
  硲彰一, 他
- Industrial Property Number
  2008-306916
- Filing Date
  2008-12-01
- Overseas
- Data Source
  KAKENHI-PROJECT-19591545
[Presentation] 肝細胞癌に対するアテゾリズマブ＋ベバシズマブ療法により完全壊死を来した症例の免疫学的解析2023
- Author(s)
  藤井敏之, 硲彰一, 日野啓輔, 沖田極, 徳光幸生, 新藤芳太郎, 中島正夫, 恒富亮一, 井岡達也, 永野浩昭
- Organizer
  第36回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] イリノテカン毒性と関連するR3HCC1遺伝子における一塩基多型2023
- Author(s)
  兼定航, 恒富亮一, 硲彰一, 荻原宏是, 浜本義彦, 新藤芳太郎, 松井洋人, 徳光幸生, 吉田晋, 飯田通久, 鈴木伸明, 武田茂, 井岡達也, 永野浩昭
- Organizer
  第129回山口大学医学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08799
[Presentation] 新規複合免疫療法による肝細胞癌の腫瘍免疫原性向上の試み2023
- Author(s)
  小佐々貴博, 中島正夫, 恒富亮一, 徳光幸生, 松井洋人, 新藤芳太郎, 玉田耕治, 宇高恵子, 坂元亨宇, 齋藤彰, 中上裕有樹, 飯田通久, 鈴木伸明, 武田茂, 井岡達也, 硲彰一, 永野浩昭
- Organizer
  第36回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 免疫チェックポイント阻害剤に抵抗性のMSH-High大腸癌に対する免疫複合製剤による治療効果の向上2023
- Author(s)
  中島正夫, 恒富亮一, 小佐々貴博, 木村祐太, 山本常則, 玉田耕治, 飯田通久, 鈴木伸明, 武田茂, 硲彰一, 井岡達也, 永野浩昭
- Organizer
  第36回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 大腸癌患者における血中 IL-6 濃度と腫瘍微小環境における免疫抑制状態、予後との関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 転移性大腸癌における T 細胞浸潤および TCR 変動に対する抗 VEGF2022
- Author(s)
  徐明、恒富亮一、清谷一馬、友近忍、中島正夫、松井洋人、徳光幸生、新藤芳太郎、吉田晋、飯田通久、鈴木伸明、武田茂、井岡達也、硲彰一、永野浩昭
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08755
[Presentation] 転移性大腸癌における T 細胞浸潤および TCR 変動に対する抗 VEGF2022
- Author(s)
  徐明、恒富亮一、清谷一馬、友近忍、中島正夫、松井洋人、徳光幸生、新藤芳太郎、吉田晋、飯田通久、鈴木伸明、武田茂、井岡達也、硲彰一、永野浩昭
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08756
[Presentation] 大腸癌切除例における IL-6 と予後および腫瘍浸潤免疫細胞の関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第35回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 大腸癌患者における腫瘍内サイトカイン発現と血中サイトカイン濃度の関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第43回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 大腸癌術前血中サイトカイン濃度と腫瘍内サイトカイン発現の関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第31回日本癌病態治療研究会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 消化器がんの高免疫原性ネオアンチゲン同定におけるAIの有用性2021
- Author(s)
  硲彰一
- Organizer
  第18回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] PP6 は Hypoxia Inducible Factor (HIF) により発現誘導され、大腸癌細胞の幹細胞性を制御している2021
- Author(s)
  藤原信行、硲彰一
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 肝癌細胞株から誘導したがん幹細胞様細胞の免疫逃避能に関する研究2021
- Author(s)
  木村祐太、硲彰一
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 教室における肝細胞癌に対する免疫療法の開発2021
- Author(s)
  松井洋人、硲彰一
- Organizer
  第42回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 新しいがん免疫療法 - Cold tumor を Hot tumor に -2021
- Author(s)
  硲彰一
- Organizer
  第25回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] MLH1 Methylation および BRAF V600E 変異同定 DNA chip によるリンチ症候群除外診断技術の確立と実用化にむけて2021
- Author(s)
  永坂岳司、硲彰一
- Organizer
  第76回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 進行消化器癌患者を対象とした新規ペプチドワクチン療法の第1相臨床試験2021
- Author(s)
  中島正夫、硲彰一
- Organizer
  第18回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 進行消化器癌患者を対象とした新規複合免疫・ペプチドワクチン療法の第 1 相臨床試験2021
- Author(s)
  鈴木伸明、硲彰一
- Organizer
  第25回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 治療抵抗性肝癌幹細胞様 Sphere 細胞における RAB3B の役割2021
- Author(s)
  恒富亮一、硲彰一
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] Identification and elucidation of liver metastasis-associated miRNAs in primary Colorectal cancer2021
- Author(s)
  Ming Xu, Shoichi Hazama, Michihisa Iida, Ryouichi Tsunedomi, Hiroto Matsui, Nobuaki Suzuki, Satoshi Matsukuma, Yukio Tokumitsu, Yoshitaro Shindo, Shinobu Tomochika, Yuki Nakagami, Noriko Maeda, Shin Yoshida, Shigeru Takeda, Tatsuya Ioka , Hiroaki Nagano
- Organizer
  日本癌学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08756
[Presentation] 肝細胞癌術後再発予防を目的とした HSP70mRNA 導入樹状細胞療法の第Ⅰ/Ⅱ相ランダム化比較臨床試験2021
- Author(s)
  松井洋人、硲彰一
- Organizer
  第18回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 肝細胞癌に対する新規がんワクチン療法による腫瘍微小環境の改変と複合免疫療法の提案2021
- Author(s)
  中島正夫、硲彰一
- Organizer
  第57回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 肝転移能亢進を示す肝癌幹細胞における免疫逃避2021
- Author(s)
  恒富亮一、硲彰一
- Organizer
  第30回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 免疫染色と CyTOF による切除可能な肝細胞癌に対する新規術前ペプチド＋免疫アジュバント併用療法施行症例の治療前生検と切除標本のTIL解析2021
- Author(s)
  中上裕有樹、硲彰一
- Organizer
  第18回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 消化器がんに対する免疫療法の最前線2021
- Author(s)
  硲彰一
- Organizer
  第34回日本バイオセラピィ学会学術集会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 進行・再発大腸癌の予後バイオマーカーとしての血清 Proteinase-3 の検討2021
- Author(s)
  古谷圭、硲彰一、鈴木伸明、吉田晋、友近忍、松隈聰、松井洋人、徳光幸生、新藤芳太郎、渡邊裕策、飯田通久、武田茂、井岡達也、永野浩昭
- Organizer
  第34回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 肝細胞癌に対する新規がんワクチン療法による腫瘍微小環境の改変と複合免疫療法の提案2021
- Author(s)
  中島正夫、硲彰一
- Organizer
  第34回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] HCC に対する新規術前ワクチン療法施行症例の治療前生検と切除標本の免疫染色による解析2021
- Author(s)
  中上裕有樹、硲彰一
- Organizer
  第76回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 最近の免疫研究をふり返って～免疫研究の今後～2021
- Author(s)
  硲彰一
- Organizer
  第30回日本癌病態治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 切除可能な肝細胞癌に対する新規術前後ワクチン療法症例の免疫反応 ―免疫染色と CyTOF データ解析から―2021
- Author(s)
  中上裕有樹、硲彰一
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 消化器癌に対する新規複合免疫療法2021
- Author(s)
  硲彰一
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] 大腸癌肝転移に関与する癌細胞由来マイクロ RNA の同定と制御するメカニズムの解明2021
- Author(s)
  徐明、硲彰一
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08711
[Presentation] HCCに対する新規術前後ワクチン療法症例の免疫反応－マスサイトメトリーによるT細胞の探索的データ解析－2020
- Author(s)
  中上裕有樹、硲彰一、玉田耕治、宇高恵子、土肥俊、坂元亨宇、齋藤彰、秋永士朗、安達圭志、松井洋人、新藤芳太郎、松隈聰、徳光幸生、友近忍、飯田通久、吉田晋、恒富亮一、鈴木伸明、武田茂、永野浩昭
- Organizer
  第41回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] "切除可能肝細胞癌に対する微小環境をターゲットにした新規ペプチドワクチン療法"2020
- Author(s)
  鈴木伸明、硲彰一、新藤芳太郎、徳光幸生、中島正夫、松隈聰、松井洋人、中上裕有樹、兼清信介、友近忍、前田訓子、恒富亮一、吉田晋、飯田通久、武田茂、吉野茂文、小笠原定久、坂元亨宇、加藤直也、永野浩昭
- Organizer
  第42回日本癌局所療法研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 肝癌幹細胞における RAB3B の機能解析2020
- Author(s)
  恒富亮一、吉村清、松隈聰、徳光幸生、新藤芳太郎、松井洋人、鈴木伸明、武田茂、硲彰一、永野浩昭
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 切除可能なHCCに対する新規術前後ペプチドワクチン療法症例の組織病理・免疫的反応2020
- Author(s)
  中上裕有樹、硲彰一、玉田耕治、土肥俊、坂元亨宇、加藤直也、齋藤彰、安達圭志、徐明、松井洋人、新藤芳太郎、松隈聰、徳光幸生、恒富亮一、永野浩昭
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] "RAB3B gene was identified as a key gene in induced liver cancer stem-like sphere cells　（治療抵抗性肝癌幹細胞様 Sphere 細胞における RAB3B 遺伝子）"2020
- Author(s)
  Ryouichi Tsunedomi, Kiyoshi Yoshimura, Satoshi Matsukuma,Hiroto Matsui, Shinsuke Kanekiyo, Yoshitaro Shindo, Yukio Tokumitsu, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda,Tatsuya Ioka, Shoichi Hazama, Hiroaki Nagano
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 大腸癌切除例における腫瘍浸潤リンパ球と血中炎症関連マーカーの関係の検討2020
- Author(s)
  山本常則、硲彰一、新藤芳太郎、徳光幸生、友近忍、吉田晋、飯田通久、鈴木伸明、武田茂、永野浩昭
- Organizer
  日本消化器外科学会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 大腸癌ペプチドワクチン療法における効果予測マーカーとしてのSiglec-7の検討2019
- Author(s)
  山田健介、硲彰一、友近忍、吉田晋、飯田通久、鈴木伸明、武田茂、吉野茂文、上野富雄、永野浩昭
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 膵癌術前化学療法が患者免疫学的プロファイルに与える影響の検討2019
- Author(s)
  中島正夫、硲彰一、山本常則、山田健介、中上裕有樹、徳光幸生、松井洋人、新藤芳太郎、松隈聰、兼清信介、友近忍、吉田晋、飯田通久、鈴木伸明、武田茂、吉野茂文、永野浩昭
- Organizer
  第32回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] がんワクチン療法・複合免疫療法における創薬研究2019
- Author(s)
  硲彰一、鈴木伸明、吉田晋、友近忍、徳光幸生、新藤芳太郎、松井洋人、松隈聰、中島正夫、中島千代、山本常則、千々松日香里、中上裕有樹、武田茂、飯田通久、兼清信介、玉田耕治、宇高恵子、吉野茂文、永野浩昭
- Organizer
  第32回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] ネオアンチゲンをターゲットとした膵癌免疫療法の開発2019
- Author(s)
  新藤芳太郎、硲彰一、恒富亮一、徳光幸生、中島正夫、松井洋人、松隈聰、兼清信介、友近忍、吉田晋、飯田通久、鈴木伸明、武田茂、吉野茂文、森崎隆、遠藤格、玉田耕治、永野浩昭
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 大腸癌に対する免疫療法のバイオマーカー探索と新規複合免疫療法の開発2019
- Author(s)
  硲彰一、鈴木伸明、友近忍、吉田晋、兼定航、松井洋人、中島正夫、山本常則、千々松日香里、中上裕有樹、新藤芳太郎、兼清信介、徳光幸生、恒富亮一、飯田通久、武田茂、吉野茂文、上野富雄、玉田耕治、永野浩昭
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 消化器癌に対する新規ペプチドワクチン療法第1相試験2019
- Author(s)
  中島正夫、硲彰一、玉田耕治、宇高恵子、土肥俊、松井洋人、新藤芳太郎、徳光幸生、松隈聰、友近忍、飯田通久、吉田晋、鈴木伸明、武田茂、永野浩昭
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 複合免疫ペプチド療法第I相試験における抑制性免疫解除の検討2019
- Author(s)
  友近忍、硲彰一、鈴木伸明、吉田晋、徳光幸生、兼清信介、新藤芳太郎、前田訓子、飯田通久、武田茂、山本滋、吉野茂文、上野富雄、永野浩昭
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 大腸癌に対する免疫療法のバイオマーカー探索と新規複合免疫療法の開発2019
- Author(s)
  硲彰一、鈴木伸明、吉田晋、友近忍、兼定航、松井洋人、中島正夫、新藤芳太郎、兼清信介、徳光幸生、恒富亮一、飯田通久、武田茂、吉野茂文、上野富雄、永野浩昭
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 良好な患者栄養状態は末梢血リンパ球の免疫抑制状態を改善し膵癌ペプチドワクチン療法の効果向上に寄与する2018
- Author(s)
  中島正夫、硲彰一、鈴木伸明、新藤芳太郎、竹之内寛子、松井洋人、兼清信介、友近忍、徳久善弘、武田茂、吉野茂文、田中浩昭、有賀淳、楳田祐三、島田光生、藤田知信、川上裕、玉田耕治、上野富雄、永野浩昭
- Organizer
  第39回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 消化器癌に対する新規複合免疫・ペプチドワクチン療法における細胞性免疫の解析2018
- Author(s)
  鈴木伸明、硲彰一、中島正夫、松隈聡、松井洋人、新藤芳太郎、兼清信介、徳光幸生、友近忍、前田訓子、飯田通久、吉田晋、武田茂、山本滋、吉野茂文、玉田耕治、上野富雄、永野浩昭
- Organizer
  第31回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] Current status and future perspectives of immunotherapy for gastrointestinal cancer2018
- Author(s)
  S Hazama、N Suzuki、S Kanekiyo、K Sakamoto、M Iida、Y Tokuhisa、S Takeda、S Yoshino、K Tamada、H Nagano
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 肝癌由来細胞株から誘導した癌幹細胞様細胞における転移能および上皮間葉系転換に関する解析2018
- Author(s)
  西山光郎、恒富亮一、吉村清、松隈聰、兼清信介、飯田通久、鈴木伸明、武田茂、吉野茂文、硲彰一、上野富雄、永野浩昭
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 膵癌切除後の予後予測因子としての術前PositronEmissionTomographyの有用性2018
- Author(s)
  新藤芳太郎，徳光幸生，坂本和彦，松井洋人，兼清信介，友近忍，飯田通久，徳久善弘，吉田晋，鈴木伸明，武田茂，吉野茂文，硲彰一，上野富雄，永野浩昭
- Organizer
  第93回中国四国外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] がん幹細胞様細胞と臨床サンプルとの統合解析により同定されたがん幹細胞関連遺伝子2018
- Author(s)
  恒富亮一, 西山光郎, 藤原信行, 松隈聰, 兼清信介, 友近忍, 徳光幸生, 飯田通久, 鈴木伸明, 武田茂, 山本滋, 吉野茂文, 上野富雄, 硲彰一, 永野浩昭
- Organizer
  第26回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 消化器癌に対する免疫療法の現状と革新的新規免疫療法の開発2018
- Author(s)
  硲彰一、玉田耕治、中島正夫、松隈聰、新藤芳太郎、松井洋人、兼清信介、飯田通久、鈴木伸明、吉野茂文、土肥俊、永野浩昭
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 新しい大腸癌術後再発予測マーカーとしての「Immunoscore」のインパクト2018
- Author(s)
  硲彰一、鈴木伸明、桑原太一、友近忍、田中宏典、中島正夫、松井洋人、兼清信介、徳光幸生、坂本和彦、飯田通久、徳久善弘、武田茂、山本滋、吉野茂文、川上裕、藤田知信、奥野清隆、上野富雄、永野浩昭
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 新規アジュバントを用いたマルチHLA結合がんペプチド療法の第Ｉ相試験2018
- Author(s)
  鈴木伸明、硲彰一、中島正夫、田中宏典、北原正博、松隈聰、松井洋人、兼清信介、徳光幸生、友近忍、徳久善弘、飯田通久、武田茂、山本滋、吉野茂文、玉田耕治、上野富雄、永野浩昭
- Organizer
  第39回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 膵癌幹細胞に高発現した分子calreticulinの臨床的意義2018
- Author(s)
  松隈聰, 吉村清, 藤原康弘, 井上萌子, 布施雅規, 小賀厚徳, 恒富亮一, 徳光幸生, 徳久善弘, 坂本和彦, 兼清信介, 友近忍, 飯田通久, 鈴木伸明, 武田茂, 吉野茂文, 硲彰一, 江口英利, 上野富雄, 永野浩昭
- Organizer
  第26回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 全エクソン解析により化学療法前後のネオアンチゲン候補探索を行った膵癌の1例2018
- Author(s)
  兼清信介、硲彰一、恒富亮一、松井洋人、鈴木伸明、中島正夫、田中宏典、徳光幸生、友近忍、飯田通久、武田茂、山本滋、吉野茂文、遠藤格、玉田耕治、永野浩昭
- Organizer
  第39回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] ドラッグリポジショニングによる抑制性免疫制御とペプチドカクテル＋CpGの第I相臨床試験2018
- Author(s)
  友近忍、硲彰一、鈴木伸明、田中宏典、兼清信介、松井洋人、中島正夫、桑原太一、徳光幸生、坂本和彦、武田茂、山本滋、吉野茂文、藤田知信、河上裕、奥野清隆、玉田耕治、石井健、上野富雄、永野浩昭
- Organizer
  第39回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] Treatment outcome of the Borderline Resectable/ Unresectable Pancreatic Cancer in Our Department2018
- Author(s)
  H Matsui, Y Tokuhisa, Y Tokumitsu, K Yamada, T Kuwahara, Y Fujiwara, M Nakajima, T Fuzimoto, S Matsukuma, K Sakamoto, S Kanekiyo, S Tomochika, M Iida, N Suzuki, S Takeda, S Yoshino, S Hazama, T Ueno, H Nagano
- Organizer
  第30回日本肝胆膵外科学会・学術集会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 当科におけるBorderline resectable膵癌に対する治療戦略と成績2018
- Author(s)
  新藤芳太郎, 徳光幸生, 松井洋人, 中島正夫, 松隈聰, 兼清信介, 友近忍, 吉田晋, 飯田通久, 鈴木伸明, 武田茂, 吉野茂文, 硲彰一, 上野富雄, 永野浩昭
- Organizer
  第80回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] ネオアンチゲンを標的とした膵癌に対する新規免疫療法の開発2018
- Author(s)
  新藤芳太郎、硲彰一、恒富亮一、中島正夫、松井洋人、松隈聰、兼清信介、徳光幸生、友近忍、吉田晋、飯田通久、鈴木伸明、武田茂、吉野茂文、森崎隆、遠藤格、玉田耕治、永野浩昭
- Organizer
  第31回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 誘導癌幹細胞における免疫逃避機構関連遺伝子の同定2018
- Author(s)
  恒富亮一、吉村清、松隈聰、西山光郎、兼清信介、徳光幸生、友近忍、飯田通久、鈴木伸明、武田茂、山本滋、吉野茂文、硲彰一、上野富雄、永野浩昭
- Organizer
  第56回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 切除不能再発膵癌に対するペプチドワクチン療法における予後予測バイオマーカーの探索2018
- Author(s)
  新藤芳太郎、硲彰一、徳光幸生、友近忍、吉田晋、飯田通久、鈴木伸明、武田茂、吉野茂文、河上裕、中村祐輔、上野富雄、永野浩昭
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 大腸癌化学療法・分子標的治療における効果・毒性のゲノミック・バイオマーカー探索2012
- Author(s)
  硲彰一
- Organizer
  第45回制癌剤適応研究会
- Place of Presentation
  国際ファッションセンター東京
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] 大腸癌治療におけるバイオマーカーの現状と展望2012
- Author(s)
  硲彰一
- Organizer
  第1回茨城大腸癌研究会
- Place of Presentation
  オークラホテルつくば市(招待講演)
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] 新しい遺伝子多型解析による大腸癌化学療法(FOLFIRI)の効果予測システムの開発2011
- Author(s)
  硲彰一, 他
- Organizer
  第44回制癌剤適応研究会
- Place of Presentation
  熊本市、ホテル日航熊本
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] Genotype subset selection of multi-UGT1As polymorphisms can predict severe neutropenia and tumor responses of metastatic CRC patients received FOLFIRI regimen2010
- Author(s)
  Shoichi Hazama, et al.
- Organizer
  The 9th International Conference of the Asian Clinical Oncology Society
- Place of Presentation
  岐阜市、岐阜グランドホテル
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] 大腸がん化学療法新時代～KRAS遺伝子型によるPersonalized Therapy～2010
- Author(s)
  硲彰一
- Organizer
  第99回日本病理学会総会・ランチョンセミナー
- Place of Presentation
  東京都・京王プラザホテル
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] 大腸がん治療新時代Personalized Therapyの現状と今後UGT1As遺伝子多型で予測するIrinotecanの毒性と効果2010
- Author(s)
  硲彰一, 日野田裕治, 三嶋秀行, 坂本純一, 岡正朗
- Organizer
  日本癌治療学会
- Place of Presentation
  京都国立京都国際会館
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] UGT1As遺伝子多型で予測するIrinotecanの毒性と効果2010
- Author(s)
  硲彰一, 他
- Organizer
  日本癌治療学会第48回学術集会
- Place of Presentation
  京都市、国立京都国際会館
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] UGTIA多型の遺伝子型サブセット選択はFOLFIRI投与mCRC患者の毒性及び腫瘍反応性を予測する(Genotype subset selection of UGTIAs polymorphisms can predict toxicity and tumor response of mCRC pts received FOLFIRI)(英語)2009
- Author(s)
  硲彰一, 日野田裕治, 岡山直子, 浜本義彦, 藤田悠介, 三嶋秀行, 坂本純一, 岡正朗
- Organizer
  日本癌学会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] 消化器癌化学療法の効果予測(抗癌剤感受性試験など)新しい遺伝子多型解析による大腸癌化学療法(FOLFIRI)の効果予測システムの開発2009
- Author(s)
  硲彰一, 三嶋秀行, 加藤健志, 高橋賢一, 野澤寛, 木村文彦, 安藤秀明, 小林道也, 坂本純一, 岡正朗
- Organizer
  日本臨床外科学会
- Place of Presentation
  京都国立京都国際会館
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] 消化器癌化学療法の効果予測(抗癌剤感受性試験など)新しい遺伝子多型解析による大腸癌化学療法(FOLFIRI)の効果予測システムの開発2009
- Author(s)
  硲彰一
- Organizer
  日本臨床外科学会
- Place of Presentation
  京都市・国立京都国際会館
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21591725
[Presentation] UGT1A1 *6 IS A PREDICTIVE MARKER OF SEVERE NEUTROPENIA FOR METASTATIC CRC PATIENTS RECEIVED FOLFIRI IN JAPAN2008
- Author(s)
  S Hazama, et al.
- Organizer
  The 33rd ESMO (European society of medical oncology)Congress
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-19591545
[Presentation] UGT1A1 *6 is a predictive marker of severe neutropenia for metastatic CRC patients received FOLFIRI in JAPAN2008
- Author(s)
  S. Hazama, Y. Okuyama, T. Kato, K. Takahashi, H. Nozawa, N. Okayama, Y. Hinoda, M. Oka, J. Sakamoto, H. Mishima
- Organizer
  The 33rd ESMO (European society of medical oncology) Congress
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-19591545
[Presentation] UGT1As polymorphisms predict toxicity in colorectal cancer patients treated with different recommended doses of irinotecan oriented by UGT1A1^*28 polymorphism based on previous phase I study.2007
- Author(s)
  S Hazama, et. al.
- Organizer
  2007 ASCO Annual Meeting
- Place of Presentation
  Chicago/IL/USA
- Data Source
  KAKENHI-PROJECT-19591545
[Presentation] UGT1As polymorphisms predict toxicity in colorectal cancer patients treated with different recommended doses of irinotecan oriented by UGT1A1*28 polymorphism based on previous phase I study2007
- Author(s)
  S. Hazama, H. Kondo, S. Yoshida, R. Shimizu, H. Ozasa, T. Yamamoto, A. Araki, S. Yoshino, N. Okayama, Y. Hinoda, M. Oka
- Organizer
  2007 ASCO Annual Meeting
- Place of Presentation
  Chicago/IL/USA
- Data Source
  KAKENHI-PROJECT-19591545
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Hazama Shoichi 硲 彰一

HAZAMA Shoichi 硲 彰一

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Identification of tumor-specific antigens to construct the novel combination immunotherapyPrincipal Investigator

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Novel immunotherapy for pancreatic cancer by the multi-HLA binding peptides derived from cancer stemness molecules.Principal Investigator

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Novel strategy for prediction of toxicity and efficacy of chemotherapy for patients with metastatic colorectal cancer.Principal Investigator

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The polymorphisms can predict the adverse effects of chemotherapy in patients with colorectal cancerPrincipal Investigator

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Hazama Shoichi 硲彰一

HAZAMA Shoichi 硲彰一