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NISHIKATA Ichiro  西片 一朗

ORCIDConnect your ORCID iD *help
Researcher Number 50253844
Other IDs
Affiliation (based on the past Project Information) *help 2015 – 2016: 九州保健福祉大学, その他部局等, 教授
2013 – 2015: 宮崎大学, 医学部, 助教
2007 – 2011: University of Miyazaki, Medicine, Research associate
2004 – 2006: 宮崎大学, 医学部, 助手
1996 – 1997: 宮崎医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
Pathological medical chemistry / Biological Sciences / General medical chemistry
Keywords
Principal Investigator
MEL1 (PRDM16) / leukemogenesis / TSA / HDAC / GATA-2 / EVI1 / MEL1S / GATA-2 gene regulation / t(1 : 3) translocation / 発現制御 … More / 発症機構 / MEL1(PRDM16) / t(1;3)転座 / 白血病 / Hematopoietic stem cells / Mice lacking EVI1 / トリコスタチンA / PCAF / t(3;3)転座 / 白血病発症機構 / 造血幹細胞 / EVI1欠損マウス / TFR / Tax / TFR1 / TSLC1 / HTLV-I Tax / prostate cancer / CAV1 / p47 / NF-kB / HTLV-1 Tax / CADM1 / ATL / Exosome … More
Except Principal Investigator
成人T細胞白血病 / NDRG2 / 転写因子 / GATA-2 / EVI1 / Streptavidin / Cotinine / Biotinylation / Hapten / Hetero-two-site enzyme immunoassay / Noncompetitive assay / 2点結合測定法 / 酵素免疫測定法 / 非競合法 / ヘテロ2点結合酸素免疫測定法 / ストレプトアビジン / コチニン / ビオチン化 / ハプテン / ヘテロ2点結合酵素免疫測定法 / 非競合測定法 / ゲノム異常 / リン酸化異常 / 感染防御 / ATLL / NIK / NF-kB / PTEN / HTLV-1 / ZEB1 / TCF8 / IgSF4 / CADM1 / TSLC1 / TCF8/ZEB1 / ゲノム / 遺伝子 / 癌 / BCL11B / 成人T細胞白血病(ATL) / TCF8(ZEB1) / TSLC1/CADM1/IgSF4 / EVIl / アセチル化修飾 / Integrin / 接着因子 / がん幹細胞 / ITGB4 / ITGA6 / DNAマイクロアレイ / 白血病幹細胞 / 造血幹細胞 Less
  • Research Projects

    (8 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (10 People)
  •  Analysis of ATL leukemogenesis through breakage of defense mechanism of HTLV-1 infection

    • Principal Investigator
      Kazuhiro Morishita
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Miyazaki
  •  The pathological analysis of ATL with a focus on exosomal secreting protein superfamily (CADM1/CAV1)Principal Investigator

    • Principal Investigator
      Nishikata Ichiro
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyushu University of Health and Welfare
      University of Miyazaki
  •  Molecular analysis of leukemogenesis of adult-T cell leukemia by genomic abnormalities

    • Principal Investigator
      MORISHITA Kazuhiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Miyazaki
  •  Evi1遺伝子群による細胞接着を介した白血病幹細胞維持機構の解明

    • Principal Investigator
      森下 和広
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Miyazaki
  •  analysis of leukemogenesis by MELS in MEL-EVI1 gene familyPrincipal Investigator

    • Principal Investigator
      NISHIKATA Ichiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Miyazaki
  •  EVI1遺伝子群によるGATA2転写制御と白血病発症機構の解析

    • Principal Investigator
      MORISHITA Kazuhiro
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Miyazaki
  •  analysis of leukemogenesis by the expression of EVI1/MEL1S, the PR domain-defective proteins, in EVI1/MEL1 gene familyPrincipal Investigator

    • Principal Investigator
      NISHIKATA Ichiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Miyazaki
  •  Studies for the Practical Use of Novel and Ultrasensitive Enzyme Immunoassay (Immune Complex Transfer Enzyme Immunoassay) of Anti-HTLV-I IgG Using Synthetic Peptides as Antigens

    • Principal Investigator
      HASHIDA Seiichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Miyazaki Medical College

All 2016 2015 2013 2011 2010 2009 2008 2005 Other

All Journal Article Presentation

  • [Journal Article] Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation2011

    • Author(s)
      Nishikata I, Nakahata S, Saito Y, Kaneda K, Ichihara E, Yamakawa N, and Morishita K
    • Journal Title

      Oncogene

      Volume: 30 Issue: 40 Pages: 196-207

    • DOI

      10.1038/onc.2011.132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390098, KAKENHI-PUBLICLY-23118523
  • [Journal Article] Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA22010

    • Author(s)
      Shimahara A, Yamakawa N, Nishikata I, Morishita K
    • Journal Title

      J. Biol. Chem

      Volume: 285 Issue: 22 Pages: 16967-16977

    • DOI

      10.1074/jbc.m110.102046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390098
  • [Journal Article] Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression2005

    • Author(s)
      Hiromi Yuasa, Yuichi Oike, Atsushi Iwama, Ichiro Nishikata, Daisuke Sugiyama, Archibald Perkins, Michael L Mucenski, Toshio Suda, Kazuhiro Morishita
    • Journal Title

      The EMBO Journal VOL 24-NO 11

      Pages: 1967-1987

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590950
  • [Presentation] CAV1含有エクソソームは前立腺がんの新規腫瘍マーカー候補である2016

    • Author(s)
      西片一朗
    • Organizer
      日本臨床検査医学会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-25461426
  • [Presentation] ATL細胞におけるCADM1高発現はp47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015

    • Author(s)
      森下数広、西片一朗、中畑新吾、市川朝永、藤井雅寛、伊波英克、田中勇悦
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      Nagoya congress center (愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461426
  • [Presentation] ATL細胞におけるCADM1高発現はP47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015

    • Author(s)
      森下和広、西片一朗、中畑新吾、市川朝永、藤井雅寛、伊波英克、田中勇悦
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25293081
  • [Presentation] ATL細胞におけるCADM1高発現はHTLV-1 Taxを含むNF-kB活性化に依存する。2013

    • Author(s)
      西片一朗
    • Organizer
      第6回HTLV-1研究会/シンポジウム
    • Place of Presentation
      東京大学 医科学研究所 講堂
    • Data Source
      KAKENHI-PROJECT-25461426
  • [Presentation] T細胞特異的TSLC1 TgマウスはATL様病態を示す2011

    • Author(s)
      市川朝永、中畑新吾、山口良二、西片一朗、森下和広
    • Organizer
      第4回HTLV-1研究会
    • Place of Presentation
      東京都文京区
    • Year and Date
      2011-09-19
    • Data Source
      KAKENHI-PROJECT-21390098
  • [Presentation] 急性骨髄性白血病の原因遺伝子EVI 1によるGATA-2転写活性化の機能解析2009

    • Author(s)
      島原明子, 山川哲生, 齋藤祐介, 西片一朗, 森下和広
    • Organizer
      日本分子生物学会第9回春季シンポジウム
    • Place of Presentation
      宮崎市
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-21390098
  • [Presentation] EVI1によるGATA転写にはPCAFによるCtBP結合領域のリジンアセチル化が必須である2008

    • Author(s)
      島原明子, 山川哲生, 西片一朗, 森下和広
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都市
    • Year and Date
      2008-10-12
    • Data Source
      KAKENHI-PROJECT-20012043
  • [Presentation] EVI1によるGATA-2転写活化にはPCAFによるCtBP結合領域のリジンアセチル化が必要である2008

    • Author(s)
      島原明子, 山川哲生, 西片一朗, 森下和広
    • Organizer
      第31回日分子生物学云云・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-20012043
  • [Presentation] Crucial lysine-acetylation in CtBP binding domain of EVI1 by P/CAF during GATA-2 transcriptional activation2008

    • Author(s)
      島原明子, 山川哲生, 西片一朗, 森下和広
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20012043
  • [Presentation] ATL細胞におけるCADM1高発現に必須なNF-kB活性化には、新規制御因子p47の発現低下が関係する

    • Author(s)
      西片一朗
    • Organizer
      第1回HTLV-1学会 学術集会
    • Place of Presentation
      東京大学 医科学研究所 講堂
    • Year and Date
      2014-08-22 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-25461426
  • [Presentation] ATL細胞におけるCADM1高発現はHTLV-1 Taxを含むNF-κB活性化に依存する.

    • Author(s)
      西片一朗、市川朝永、中畑新吾、藤井雅寛、伊波英克、白神俊幸、田中勇悦、森下和広
    • Organizer
      6回HTLV-1研究会・シンポジウム.
    • Place of Presentation
      港区 東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-25293081
  • [Presentation] 血中可溶性CADM1/TSLC1測定によるATL診断法の開発

    • Author(s)
      中武彩子、小林行治、中畑新吾、西片一朗、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡栄三朗、瀬戸山充、岡山昭彦、宇都宮與、下田和哉、渡邊俊樹、森下和広
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      2014-08-23 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-25293081
  • [Presentation] 血中可溶型CADM1/TSLC1測定によるATL診断法の開発.

    • Author(s)
      中武彩子、小林行治、西片一朗、中畑新吾、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡榮三朗、瀬戸口充、岡山昭彦、宇都宮與、下田和哉、渡邊俊樹、森下和広
    • Organizer
      HTLV-1研究会・シンポジウム
    • Place of Presentation
      港区 東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-25293081
  • 1.  MORISHITA Kazuhiro (80260321)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  NAKAHATA Shingo (80437938)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 3.  TANIWAKI Masafumi (80163640)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  SHIRAGA Toshiyuki (70363596)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  山川 哲生 (60335825)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  ICHIKAWA Tomonaga (80586230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  KANEDA Kazuko (00533209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  HASHIDA Seiichi (10156268)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  中尾 和貴 (20217657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  森下 和弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 13 results

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