NISHIKATA Ichiro 西片一朗

Researcher Number	50253844
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2016: 九州保健福祉大学, その他部局等, 教授 2013 – 2015: 宮崎大学, 医学部, 助教 2007 – 2011: University of Miyazaki, Medicine, Research associate 2004 – 2006: 宮崎大学, 医学部, 助手 1996 – 1997: 宮崎医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Pathological medical chemistry / Biological Sciences / General medical chemistry
Keywords	Principal Investigator MEL1 (PRDM16) / leukemogenesis / TSA / HDAC / GATA-2 / EVI1 / MEL1S / GATA-2 gene regulation / t(1 : 3) translocation / 発現制御 … More / 発症機構 / MEL1(PRDM16) / t(1;3)転座 / 白血病 / Hematopoietic stem cells / Mice lacking EVI1 / トリコスタチンA / PCAF / t(3;3)転座 / 白血病発症機構 / 造血幹細胞 / EVI1欠損マウス / TFR / Tax / TFR1 / TSLC1 / HTLV-I Tax / prostate cancer / CAV1 / p47 / NF-kB / HTLV-1 Tax / CADM1 / ATL / Exosome … More Except Principal Investigator 成人T細胞白血病 / NDRG2 / 転写因子 / GATA-2 / EVI1 / Streptavidin / Cotinine / Biotinylation / Hapten / Hetero-two-site enzyme immunoassay / Noncompetitive assay / 2点結合測定法 / 酵素免疫測定法 / 非競合法 / ヘテロ2点結合酸素免疫測定法 / ストレプトアビジン / コチニン / ビオチン化 / ハプテン / ヘテロ2点結合酵素免疫測定法 / 非競合測定法 / ゲノム異常 / リン酸化異常 / 感染防御 / ATLL / NIK / NF-kB / PTEN / HTLV-1 / ZEB1 / TCF8 / IgSF4 / CADM1 / TSLC1 / TCF8/ZEB1 / ゲノム / 遺伝子 / 癌 / BCL11B / 成人T細胞白血病(ATL) / TCF8(ZEB1) / TSLC1/CADM1/IgSF4 / EVIl / アセチル化修飾 / Integrin / 接着因子 / がん幹細胞 / ITGB4 / ITGA6 / DNAマイクロアレイ / 白血病幹細胞 / 造血幹細胞 Less

Analysis of ATL leukemogenesis through breakage of defense mechanism of HTLV-1 infection
- Principal Investigator
  
  Kazuhiro Morishita
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
The pathological analysis of ATL with a focus on exosomal secreting protein superfamily (CADM1/CAV1)Principal Investigator
- Principal Investigator
  
  Nishikata Ichiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University of Health and Welfare
  University of Miyazaki
Molecular analysis of leukemogenesis of adult-T cell leukemia by genomic abnormalities
- Principal Investigator
  
  MORISHITA Kazuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
Evi1遺伝子群による細胞接着を介した白血病幹細胞維持機構の解明
- Principal Investigator
  
  森下和広
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
analysis of leukemogenesis by MELS in MEL-EVI1 gene familyPrincipal Investigator
- Principal Investigator
  
  NISHIKATA Ichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Miyazaki
EVI1遺伝子群によるGATA2転写制御と白血病発症機構の解析
- Principal Investigator
  
  MORISHITA Kazuhiro
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
analysis of leukemogenesis by the expression of EVI1/MEL1S, the PR domain-defective proteins, in EVI1/MEL1 gene familyPrincipal Investigator
- Principal Investigator
  
  NISHIKATA Ichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Miyazaki
Studies for the Practical Use of Novel and Ultrasensitive Enzyme Immunoassay (Immune Complex Transfer Enzyme Immunoassay) of Anti-HTLV-I IgG Using Synthetic Peptides as Antigens
- Principal Investigator
  
  HASHIDA Seiichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Miyazaki Medical College

All 2016 2015 2013 2011 2010 2009 2008 2005 Other

All Journal Article Presentation

[Journal Article] Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation2011
- Author(s)
  Nishikata I, Nakahata S, Saito Y, Kaneda K, Ichihara E, Yamakawa N, and Morishita K
- Journal Title
  
  Oncogene
  
  Volume: 30 Issue: 40 Pages: 196-207
- DOI
  10.1038/onc.2011.132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098, KAKENHI-PUBLICLY-23118523
[Journal Article] Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA22010
- Author(s)
  Shimahara A, Yamakawa N, Nishikata I, Morishita K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Issue: 22 Pages: 16967-16977
- DOI
  10.1074/jbc.m110.102046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression2005
- Author(s)
  Hiromi Yuasa, Yuichi Oike, Atsushi Iwama, Ichiro Nishikata, Daisuke Sugiyama, Archibald Perkins, Michael L Mucenski, Toshio Suda, Kazuhiro Morishita
- Journal Title
  
  The EMBO Journal VOL 24-NO 11
  
  Pages: 1967-1987
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590950
[Presentation] CAV1含有エクソソームは前立腺がんの新規腫瘍マーカー候補である2016
- Author(s)
  西片一朗
- Organizer
  日本臨床検査医学会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-25461426
[Presentation] ATL細胞におけるCADM1高発現はp47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015
- Author(s)
  森下数広、西片一朗、中畑新吾、市川朝永、藤井雅寛、伊波英克、田中勇悦
- Organizer
  日本癌学会学術総会
- Place of Presentation
  Nagoya congress center (愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461426
[Presentation] ATL細胞におけるCADM1高発現はP47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015
- Author(s)
  森下和広、西片一朗、中畑新吾、市川朝永、藤井雅寛、伊波英克、田中勇悦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] ATL細胞におけるCADM1高発現はHTLV-1 Taxを含むNF-kB活性化に依存する。2013
- Author(s)
  西片一朗
- Organizer
  第6回HTLV-1研究会/シンポジウム
- Place of Presentation
  東京大学医科学研究所講堂
- Data Source
  KAKENHI-PROJECT-25461426
[Presentation] T細胞特異的TSLC1 TgマウスはATL様病態を示す2011
- Author(s)
  市川朝永、中畑新吾、山口良二、西片一朗、森下和広
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京都文京区
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 急性骨髄性白血病の原因遺伝子EVI 1によるGATA-2転写活性化の機能解析2009
- Author(s)
  島原明子, 山川哲生, 齋藤祐介, 西片一朗, 森下和広
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Place of Presentation
  宮崎市
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] EVI1によるGATA転写にはPCAFによるCtBP結合領域のリジンアセチル化が必須である2008
- Author(s)
  島原明子, 山川哲生, 西片一朗, 森下和広
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都市
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-20012043
[Presentation] EVI1によるGATA-2転写活化にはPCAFによるCtBP結合領域のリジンアセチル化が必要である2008
- Author(s)
  島原明子, 山川哲生, 西片一朗, 森下和広
- Organizer
  第31回日分子生物学云云・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20012043
[Presentation] Crucial lysine-acetylation in CtBP binding domain of EVI1 by P/CAF during GATA-2 transcriptional activation2008
- Author(s)
  島原明子, 山川哲生, 西片一朗, 森下和広
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20012043
[Presentation] ATL細胞におけるCADM1高発現に必須なNF-kB活性化には、新規制御因子p47の発現低下が関係する
- Author(s)
  西片一朗
- Organizer
  第１回HTLV-1学会　学術集会
- Place of Presentation
  東京大学　医科学研究所　講堂
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25461426
[Presentation] ATL細胞におけるCADM1高発現はHTLV-1 Taxを含むNF-κB活性化に依存する.
- Author(s)
  西片一朗、市川朝永、中畑新吾、藤井雅寛、伊波英克、白神俊幸、田中勇悦、森下和広
- Organizer
  ６回HTLV-1研究会・シンポジウム.
- Place of Presentation
  港区　東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] 血中可溶性CADM1/TSLC1測定によるATL診断法の開発
- Author(s)
  中武彩子、小林行治、中畑新吾、西片一朗、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡栄三朗、瀬戸山充、岡山昭彦、宇都宮與、下田和哉、渡邊俊樹、森下和広
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2014-08-23 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] 血中可溶型CADM1/TSLC1測定によるATL診断法の開発.
- Author(s)
  中武彩子、小林行治、西片一朗、中畑新吾、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡榮三朗、瀬戸口充、岡山昭彦、宇都宮與、下田和哉、渡邊俊樹、森下和広
- Organizer
  HTLV-1研究会・シンポジウム
- Place of Presentation
  港区　東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-25293081

1. MORISHITA Kazuhiro (80260321)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. NAKAHATA Shingo (80437938)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. TANIWAKI Masafumi (80163640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIRAGA Toshiyuki (70363596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 山川哲生 (60335825)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. ICHIKAWA Tomonaga (80586230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. KANEDA Kazuko (00533209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HASHIDA Seiichi (10156268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中尾和貴 (20217657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 森下和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results

NISHIKATA Ichiro 西片 一朗

Research Projects

Research Products

Co-Researchers

Analysis of ATL leukemogenesis through breakage of defense mechanism of HTLV-1 infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathological analysis of ATL with a focus on exosomal secreting protein superfamily (CADM1/CAV1)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of leukemogenesis of adult-T cell leukemia by genomic abnormalities

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evi1遺伝子群による細胞接着を介した白血病幹細胞維持機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

analysis of leukemogenesis by MELS in MEL-EVI1 gene familyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EVI1遺伝子群によるGATA2転写制御と白血病発症機構の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

analysis of leukemogenesis by the expression of EVI1/MEL1S, the PR domain-defective proteins, in EVI1/MEL1 gene familyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies for the Practical Use of Novel and Ultrasensitive Enzyme Immunoassay (Immune Complex Transfer Enzyme Immunoassay) of Anti-HTLV-I IgG Using Synthetic Peptides as Antigens

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA22010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression2005

Author(s)

Journal Title

Description

Data Source

[Presentation] CAV1含有エクソソームは前立腺がんの新規腫瘍マーカー候補である2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ATL細胞におけるCADM1高発現はp47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ATL細胞におけるCADM1高発現はP47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015

NISHIKATA Ichiro 西片一朗