Ishigami Tomoaki 石上友章

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ISHIGAMI Tomoaki 石上友章

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Researcher Number	50264651
Other IDs
External Links
Affiliation (Current)	2025: 横浜市立大学, 附属病院, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 横浜市立大学, 附属病院, 准教授 2007 – 2022: Yokohama City University, Graduate School of Medicine, Associate Professor 2007: Yokohama City University, 医学研究科, 准教授 2006: 横浜市立大学, 医学部, 準教授 1998: 横浜市立大学, 医学部・附属病院・第二内科, 助手 1997 – 1998: 横浜市立大学, 医学部, 助手 1997: 横浜市立大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Circulatory organs internal medicine Except Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Gerontological nursing / Basic Section 58060:Clinical nursing-related / Basic Section 53020:Cardiology-related / Circulatory organs internal medicine
Keywords	Principal Investigator 食塩感受性 / 尿細管 / 高血圧 / アンジオテンシノーゲン / イオントランスポーター / Nedd4L / レニン・アンジオテンシン系 / レニン / ユビキチン化 / ナトリウムチャンネル … More / 本態性高血圧症 / Nedd4-2 / 上皮性ナトリウムチャネル / ユビキチン / イオンチャンネル / 心腎連関 / ナトリウムチャネル / ナトリウム / Nedd4-2/Nedd4L / イオン・トランスポーター / 遺伝子改変動物 / sodium channel / sodium aensitivity / ion transpomer / Aldosterone sansitive distal nebhron / essential hypemension / アルドステロン感受性尿細管 / アルドステロン感受性ネフロン / NEDD4L / アミロライド / ナトリウム代謝 / ENaC / 内分泌 / NPC2 / 腎臓尿細管 / 上皮性ナトリウムチャンネル / 尿細管レニンアンジオテンシン系 / ナトリウム輸送 / プロモーター / 遺伝子多型 … More Except Principal Investigator 評価 / 再生 / 幹細胞 / 心筋梗塞 / 栄養 / 加齢 / 免疫 / 炎症 / 間葉系幹細胞 / 嚥下 / 効果検証 / 介入プログラム / 重症心疾患 / 組織再生 / 心疾患 / 自己抗体 / 脾臓B2細胞 / Leaky Gut Syndrome / 腸管バリア / 腸管漏洩症候群 / 脾臓 / B2細胞 / 液性免疫 / 腸内細菌 / 動脈硬化症 / 運動 / 効果評価 / 気管挿管 / 循環 / 呼吸 / 効果 / 心臓疾患 / 重症患者 / プログラム開発 / リハビリテーション / 循環器疾患 / 摂食嚥下障害 / 切片 / 細胞培養 / モデルマウス / Neuronal nitric oxide synthase / Regulation of gene expression / Angiotensin receptor / Renin / Gene Targeting / Angiotensinogen / Renin Angiotensin System / ジーンターゲッティング / アンジオテンシノーゲン / レニン・アンジオチンシン系 / 神経型一酸化窒素合成酵素 / 遺伝子発現調節 / アンジオテンシン受容体 / レニン / ジーンターゲティング / アンジオテンシンノーゲン / レニン・アンジオテンシン系 Less

Development and effectiveness of an intervention programme for the systemic, swallowing and nutritional status of patients with severe cardiac disease.
- Principal Investigator
  
  千葉由美
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Yokohama City University
Effects of nutrition, aging, and stem cell against inflammation on high-risk heart disease, and evaluation of tissue regeneration ability.
- Principal Investigator
  
  千葉由美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Yokohama City University
Elucidation for tubular mechanism for salt sensitivity and hypertension focusing of "Excitation-Transcription Coupling"Principal Investigator
- Principal Investigator
  
  石上友章
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Yokohama City University
Elucidation for Molecular Pathophysiology of Atherosclerosis Focusing of Commensal Microbe and Splenic B2 Cells
- Principal Investigator
  
  荒川健太郎
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Yokohama City University
Evaluation of effects on age and tissue regeneration by exercise intervention on high-risk myocardial infarction
- Principal Investigator
  
  CHIBA Yumi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Yokohama City University
Salt Sensitivity, Hypertension and Tubular MechanismPrincipal Investigator
- Principal Investigator
  
  ISHIGAMI Tomoaki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
Development and Evaluation of Rehabilitation Program depending on Patients with Severe Body and Dysphagic Conditions
- Principal Investigator
  
  CHIBA Yumi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gerontological nursing
- Research Institution
  Yokohama City University
Elucidation and Expansion of Molecular Physiology of Salt Sensitivity and Hypertensin Based on Tubular Mechanism.Principal Investigator
- Principal Investigator
  
  ISHIGAMI Tomoaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
Influence of aging and exercise on engraftment after stem cell transplantation into myocardial infarction model mice
- Principal Investigator
  
  CHIBA Yumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gerontological nursing
- Research Institution
  Yokohama City University
Analyses of molecular mechanism of hypertensive cardio-renal relationships focusing on post-transcriptional regulations of ion-transporters.Principal Investigator
- Principal Investigator
  
  ISHIGAMI Tomoaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
Identifications for molecular mechanisms of essential hypertension in terms of urinary tubular ion transporter and human NEDD4L.Principal Investigator
- Principal Investigator
  
  ISHIGAMI Tomoaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
Molecular Pathopbysiological Reseatch of ubiquitin ligase,human Nodd4L, for the development ofessentialhyportensionPrincipal Investigator
- Principal Investigator
  
  ISHIGAMI Tomoaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
ヒト心臓キマーゼ遺伝子の循環器疾患における役割の検討Principal Investigator
- Principal Investigator
  
  石上友章
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
Molecular biological studies on regulatory systems of the circulation in angiotensinogen gene knockout mice.
- Principal Investigator
  
  UMEMURA Satoshi, 石井當男
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University

[Book] 循環器レビュー&トピックス2014
- Author(s)
  石上友章ほか
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23591221
[Book] 循環器レビュー&トピックス2013
- Author(s)
  石上友章、船橋伸禎、竹内正明、内藤亮、土肥智貴、代田浩之、天野恵子、小向賢一、北端宏規、赤坂隆史、台和興、石原正治、福澤茂、小山卓史、伊藤健太、下川宏明、安斉俊久、高田佳史、長山雅俊、鄭忠和ほか
- Total Pages
  217
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23591221
[Book] 選択的アルドステロンブロッカーのすべて2009
- Author(s)
  石上友章, ほか
- Total Pages
  239
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-20590978
[Book] 心臓血管疾患における遺伝学的検査と遺伝カウンセリングに関するガイドライン2007
- Author(s)
  中澤誠, 石上友章他
- Publisher
  Circulation Journal, Vol 70, Supplement IV
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Effects of dietary n-3/n-6 fatty acid content on post-operative adhesions in myocardial infarction mice.2023
- Author(s)
  Yumi Chiba, Ikumi Nakamura, Kenji Ishihara, Takuya Seko, Tomoaki Ishigami.
- Journal Title
  
  Clinical Nutrition Open Science
  
  Volume: in press Pages: 88-100
- DOI
  10.1016/j.nutos.2023.03.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19659, KAKENHI-PROJECT-23K24648
[Journal Article] Clinical impact of left ventricular systolic dysfunction in patients undergoing dialysis access surgery2023
- Author(s)
  Saka Sanae、Konishi Masaaki、Kamimura Daisuke、Wakui Hiromichi、Matsuzawa Yasushi、Okada Kozo、Kirigaya Jin、Iwahashi Noriaki、Sugano Teruyasu、Ishigami Tomoaki、Hirawa Nobuhito、Hibi Kiyoshi、Ebina Toshiaki、Kimura Kazuo、Tamura Kouichi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 27 Issue: 4 Pages: 374-381
- DOI
  10.1007/s10157-023-02323-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-23K06871, KAKENHI-PROJECT-23K24648
[Journal Article] Association between sarcopenia and exercise capacity in patients with pulmonary hypertension without left heart disease2023
- Author(s)
  Nakayama Mina、Konishi Masaaki、Sugano Teruyasu、Okamura Masatsugu、Gohbara Masaomi、Iwata Kiwamu、Nakayama Naoki、Akiyama Eiichi、Komura Naohiro、Nitta Manabu、Kawaura Noriyuki、Ishigami Tomoaki、Hibi Kiyoshi、Ishikawa Toshiyuki、Nakamura Takeshi、Tamura Kouichi、Kimura Kazuo
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 387 Pages: 131115-131115
- DOI
  10.1016/j.ijcard.2023.06.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24648
[Journal Article] Severity by National Institute of Health Stroke Scale Score and Clinical Features of Stroke Patients with Patent Foramen Ovale Stroke and Atrial Fibrillation2021
- Author(s)
  Abe Kaito、Hasegawa Fumiya、Nakajima Ryota、Fukui Hidetoshi、Shimada Moto、Miyazaki Takahiro、Doi Hiroshi、Endo Goro、Kanbara Kaori、Mochida Yasuyuki、Okuda Jun、Maeda Nobuya、Isoshima Akira、Tamura Koichi、Ishigami Tomoaki
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 2 Pages: 332-332
- DOI
  10.3390/jcm10020332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Characteristics of patients with adult congenital heart disease treated by non-specialized doctors: The potential loss of follow-up2021
- Author(s)
  Nitta Manabu、Ochiai Ryota、Nakano Shintaro、Nakashima Rie、Matsumoto Katsumi、Sugano Teruyasu、Ishigami Tomoaki、Ishikawa Toshiyuki、Tamura Kouichi、Nakano Yusuke、Watanabe Shigeo、Hokosaki Tatsunori、Machida Daisuke、Masuda Munetaka、Kimura Kazuo
- Journal Title
  
  Journal of Cardiology
  
  Volume: 77 Issue: 1 Pages: 17-22
- DOI
  10.1016/j.jjcc.2020.06.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Cell Surface and Functional Features of Cortical Bone Stem Cells2021
- Author(s)
  Sasaki Norihiko、Itakura Yoko、Mohsin Sadia、Ishigami Tomoaki、Kubo Hajime、Chiba Yumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 11849-11849
- DOI
  10.3390/ijms222111849
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11666, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-21K19659, KAKENHI-PROJECT-19K11759
[Journal Article] Rationale and Design of the Orencia Atherosclerosis and Rheumatoid Arthritis Study (ORACLE Arthritis Study): Implications of Biologics against Rheumatoid Arthritis and the Vascular Complications, Subclinical Atherosclerosis2021
- Author(s)
  Ishigami Tomoaki、Nanki Toshihiro、Sugawara Takuya、Uchida Kotaro、Takeda Hiroyuki、Sawasaki Tatsuya、Chen Lin、Doi Hiroshi、Arakawa Kentaro、Saigo Sae、Yoshimi Ryusuke、Taguri Masataka、Kimura Kazuo、Hibi Kiyoshi、Wakui Hiromichi、Azushima Kengo、Tamura Kouichi、on behalf of ORACLE Arthritis Investigators
- Journal Title
  
  Methods and Protocols
  
  Volume: 4 Issue: 4 Pages: 83-83
- DOI
  10.3390/mps4040083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-20K08478
[Journal Article] An interesting link between quality of sleep and a measure of blood pressure variability2020
- Author(s)
  Tamura Kouichi、Uchida Kotaro、Ishigami Tomoaki
- Journal Title
  
  The Journal of Clinical Hypertension
  
  Volume: 23 Issue: 2 Pages: 331-333
- DOI
  10.1111/jch.14160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Randomized controlled trial of landiolol, a short-acting beta-1 adrenergic receptor blocker, illustrating changes in high-molecular weight adiponectin levels after elective percutaneous coronary intervention2020
- Author(s)
  Kiyokuni Masayoshi、Konishi Masaaki、Saigusa Yusuke、Iwata Kiwamu、Nakayama Naoki、Komura Naohiro、Sugano Teruyasu、Ishigami Tomoaki、Ishikawa Toshiyuki、Yamanaka Takeharu、Tamura Kouichi、Kimura Kazuo
- Journal Title
  
  Heart and Vessels
  
  Volume: 35 Issue: 11 Pages: 1510-1517
- DOI
  10.1007/s00380-020-01637-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Gut microbiota and atherosclerosis: role of B cell for atherosclerosis focusing on the gut-immune-B2 cell axis2020
- Author(s)
  Chen Lin、Ishigami Tomoaki、Doi Hiroshi、Arakawa Kentaro、Tamura Kouichi
- Journal Title
  
  Journal of Molecular Medicine
  
  Volume: 98 Issue: 9 Pages: 1235-1244
- DOI
  10.1007/s00109-020-01936-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08478, KAKENHI-PROJECT-17K09730
[Journal Article] Successful screening of sleep-disordered breathing using a pacemaker-based algorithm in Japan2019
- Author(s)
  Taguchi Yuka、Matsushita Kohei、Ishikawa Toshiyuki、Matsumoto Katsumi、Hosoda Junya、Iguchi Kouhei、Matsushita Hirooki、Kubota Kazumi、Sumita Shinnichi、Ishigami Tomoaki、Tamura Kouichi
- Journal Title
  
  Journal of Cardiology
  
  Volume: 73 Issue: 5 Pages: 394-400
- DOI
  10.1016/j.jjcc.2018.10.007
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice.2019
- Author(s)
  Arakawa K, Ishigami T(correspond), Nakai-Sugiyama M, Chen L, Doi H, Kino T, Minegishi S,Saigoh-Teranaka S, Sasaki-Nakashima R, Hibi K, Kimura K, Tamura K.
- Journal Title
  
  PLoS One
  
  Volume: 14(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Doxorubicin induces trans-differentiation and MMP1 expression in cardiac fibroblasts via cell death-independent pathways.2019
- Author(s)
  Narikawa M, Umemura M, Tanaka R, Hikichi M, Nagasako A, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 14 Issue: 9 Pages: e0221940-e0221940
- DOI
  10.1371/journal.pone.0221940
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-19H03657
[Journal Article] 心筋梗塞モデルマウスを用いた超音波検査法の手技に関する評価2019
- Author(s)
  荻野千菜美, 千葉由美, 峯岸慎太郎, 石上友章
- Journal Title
  
  横浜看護学雑誌
  
  Volume: 12(1) Pages: 61-69
- NAID
  120006595097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Successful screening of　sleep-disordered breathing using a pacemaker-based algorithm in Japan.2019
- Author(s)
  Taguchi Y, Matsushita K, Ishikawa T, Matsumoto K, Hosoda J, Iguchi K, Matsushita H, Kubota K, Sumita S, Ishigami T, Tamura K.
- Journal Title
  
  J Cardiol
  
  Volume: 73(5) Pages: 394-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line.2019
- Author(s)
  Yamaji T, Yamashita A, Wakui H, Azushima K, Uneda K, Fujikawa Y, Haku S,Kobayashi R, Ohki K, Haruhara K, Kinguchi S, Ishii T, Yamada T, Urate S, SuzukiT, Abe E, Tanaka S, Kamimura D, Ishigami T, Toya Y, Takahashi H, Tamura K.
- Journal Title
  
  Sci Rep
  
  Volume: 9(1) Pages: 16550-16550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice.2019
- Author(s)
  Kentaro Arakawa, Tomoaki Ishigami, et al.
- Journal Title
  
  PLoS One
  
  Volume: 14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line.2019
- Author(s)
  Yamaji T, Ishigami T, et al.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Pages: 16550-16550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice2019
- Author(s)
  Kengo Azushima, Kazushi Uneda, Tomoaki Ishigami , et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension2019
- Author(s)
  Sho Kinguchi, Hiromichi Wakui, Tomoaki Ishigami et al.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Native T1 time and extracellular volume fraction in differentiation of normal myocardium from non-ischemic dilated and hypertrophic cardiomyopathy myocardium: A systematic review and meta-analysis2019
- Author(s)
  Minegishi S, Kato S, Takase-Minegishi K, Horita N, Azushima K, Wakui H,Ishigami T, Kosuge M, Kimura K, Tamura K.
- Journal Title
  
  Int J Cardiol Heart Vasc
  
  Volume: 25 Pages: 100422-100422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Microbiota-derived Trimethylamine N-oxide Predicts Cardiovascular Risk After STEMI.2019
- Author(s)
  Matsuzawa Y, Nakahashi H, Konishi M, Sato R, Kawashima C, Kikuchi S, Akiyama E, Iwahashi N, Maejima N, Okada K, Ebina T, Hibi K, Kosuge M, Ishigami T, Tamura K, Kimura K.
- Journal Title
  
  Sci Rep
  
  Volume: 9(1) Pages: 11647-11647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Doxorubicin induces trans-differentiation and MMP1 expression in cardiac fibroblasts via cell death-independent pathways.2019
- Author(s)
  Narikawa M, Ishigami T, et al.
- Journal Title
  
  PLoS One
  
  Volume: 14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice.2019
- Author(s)
  Azushima K, Uneda K, Wakui H, Ohki K, Haruhara K, Kobayashi R, Haku S,Kinguchi S, Yamaji T, Minegishi S, Ishigami T, Yamashita A, Tamura K.
- Journal Title
  
  Sci Rep
  
  Volume: 9(1) Pages: 6201-6201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension.2019
- Author(s)
  Kinguchi S, Wakui H, Azushima K, Haruhara K, Koguchi T, Ohki K, Uneda K,Matsuda M, Haku S, Yamaji T, Yamada T, Kobayashi R, Minegishi S, Ishigami T,Yamashita A, Fujikawa T, Tamura K.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 8(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19689
[Journal Article] Successful Screening of Sleep-Disordered Breathing Using a Pacemaker-Based Algorithm in Japan2019
- Author(s)
  Yuka Taguchi, Kohei Matsushita, Tomoaki Ishigami, et al
- Journal Title
  
  J Cardiol
  
  Volume: 73 Pages: 394-400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Arterial wall hypertrophy is ameliorated by α2-adrenergic receptor antagonist or aliskiren in kidneys of angiotensinogen-knockout mice2018
- Author(s)
  Nakamori Haruka、Yoshida Shin-ichiro、Ishiguro Hiroaki、Suzuki Shota、Yasuzaki Hiroaki、Hashimoto Tatsuo、Ishigami Tomoaki、Hirawa Nobuhito、Toya Yoshiyuki、Umemura Satoshi、Tamura Kouichi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 22 Issue: 4 Pages: 773-781
- DOI
  10.1007/s10157-017-1520-8
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice2018
- Author(s)
  haku Sona、Wakui Hiromichi、Azushima Kengo、Haruhara Kotaro、Kinguchi Sho、Ohki Kohji、Uneda Kazushi、Kobayashi Ryu、Matsuda Miyuki、Yamaji Takahiro、Yamada Takayuki、Minegishi Shintaro、Ishigami Tomoaki、Yamashita Akio、Ohashi Kenichi、Tamura Kouichi
- Journal Title
  
  BioMed Research International
  
  Volume: 2018 Pages: 1-9
- DOI
  10.1155/2018/2817045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09313, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K19665, KAKENHI-PROJECT-17K09730
[Journal Article] New non-invasive indexes of arterial stiffness are significantly correlated with severity and complexity of coronary atherosclerosis2018
- Author(s)
  Doi Hiroshi、Ishigami Tomoaki、Nakashima-Sasaki Rie、Kino Tabito、Chen Lin、Arakawa Kentaro、Teranaka Sae、Minegishi Shintaro、Abe Kaito、Ishikawa Toshiyuki、Sugano Teruyasu、Tamura Kouichi
- Journal Title
  
  Clinical and Experimental Hypertension
  
  Volume: 41 Issue: 2 Pages: 187-193
- DOI
  10.1080/10641963.2018.1465072
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Angiotensin receptor-binding molecule in leukocytes in association with the systemic and leukocyte inflammatory profile2018
- Author(s)
  Haruhara Kotaro、Wakui Hiromichi、Azushima Kengo、Kurotaki Daisuke、Kawase Wataru、Uneda Kazushi、Haku Sona、Kobayashi Ryu、Ohki Kohji、Kinguchi Sho、Ohsawa Masato、Minegishi Shintaro、Ishigami Tomoaki、Matsuda Miyuki、Yamashita Akio、Nakajima Hideaki、Tamura Tomohiko、Tsuboi Nobuo、Yokoo Takashi、Tamura Kouichi
- Journal Title
  
  Atherosclerosis
  
  Volume: 269 Pages: 236-244
- DOI
  10.1016/j.atherosclerosis.2018.01.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-16K09647, KAKENHI-PROJECT-17K09730
[Journal Article] Relationship between sleep-disordered breathing and renal dysfunction in acute coronary syndrome2018
- Author(s)
  Kiyokuni Masayoshi、Kawashima Chika、Konishi Masaaki、Sakamaki Kentaro、Iwata Kiwamu、Nakayama Naoki、Komura Naohiro、Kosuge Masami、Sugano Teruyasu、Ishigami Tomoaki、Endo Tsutomu、Ishikawa Toshiyuki、Yamanaka Takeharu、Kimura Kazuo、Tamura Kouichi
- Journal Title
  
  Journal of Cardiology
  
  Volume: 71 Issue: 2 Pages: 168-173
- DOI
  10.1016/j.jjcc.2017.07.017
- Data Source
  KAKENHI-PROJECT-17K09730
[Journal Article] Acute hyperthermia inhibits TGF-β1-induced cardiac fibroblast activation via uppression of Akt Signaling.2018
- Author(s)
  Narikawa M, Umemura M, Tanaka R, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 6277-6277
- DOI
  10.1038/s41598-018-24749-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-17K09730
[Journal Article] Hydrostatic pressure suppressed fibrotic change via Akt/GSK-3 signaling in human cardiac fibroblasts.2018
- Author(s)
  Tanaka R, Umemura M, Narikawa M, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  Physiol Rep.
  
  Volume: 6 Issue: 9 Pages: e13687-e13687
- DOI
  10.14814/phy2.13687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-17K09730
[Journal Article] An Isoform of Nedd4-2 Plays a Pivotal Role in Electrophysiological Cardiac Abnormalities2017
- Author(s)
  Minegishi Shintaro、Ishigami Tomoaki、Kawamura Hisho、Kino Tabito、Chen Lin、Nakashima-Sasaki Rie、Doi Hiroshi、Azushima Kengo、Wakui Hiromichi、Chiba Yumi、Tamura Kouichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 6 Pages: 1268-1268
- DOI
  10.3390/ijms18061268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17H04458
[Journal Article] An isoform of Nedd4-2 is critically involved in the renal adaptation to high oral salt intake.2016
- Author(s)
  Minegishi S, Ishigami T(corresponding author), Kino T, Chen L, Nakashima-Sasaki R, Araki N, Yatsu K,Fujita M, Umemura S.
- Journal Title
  
  Sci Rep. 2016 Jun 3;6:27137.
  
  Volume: 6 Issue: 1 Pages: 27137-27149
- DOI
  10.1038/srep27137
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461257
[Journal Article] Identification of Bona Fide Alternative Renin Transcripts Expressed Along Cortical Tubules and Potential Roles in Promoting Insulin Resistance In Vivo Without Significant Plasma Renin Activity Elevation2014
- Author(s)
  Ishigami T, Kino T, Chen L, Minegishi S, Araki N, Umemura M, Abe K, Sasaki R, Yamana H, Umemura S
- Journal Title
  
  Hypertension
  
  Volume: (Epub ahead of print)(PubMed PMID:24777979)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591221
[Journal Article] Effect of impaired renal function on the maintenance dose of warfarin in Japanese patients2014
- Author(s)
  Ichihara N, Ishigami T, Umemura S.
- Journal Title
  
  Jouranl of Cardiology
  
  Volume: 65(3) Issue: 3 Pages: 178-84
- DOI
  10.1016/j.jjcc.2014.08.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461257
[Journal Article] Clinical significance of collateral superficial vein across clavicle in patients with cardiovascular implantable electronic device.2014
- Author(s)
  Hosoda J, Ishikawa T, Ishigami T, et al.
- Journal Title
  
  Circulation Journal
  
  Volume: 78(8) Pages: 1846-50
- NAID
  130004926988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461257
[Journal Article] Identification of Bona Fide Alternative Renin Transcripts2014
- Author(s)
  Ishigami T, Kino T, Chen L, et al.
- Journal Title
  
  Hypertension
  
  Volume: 64(1) Issue: 1 Pages: 125-33
- DOI
  10.1161/hypertensionaha.114.03394
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461257
[Journal Article] Genetic variation in NEDD4L, salt sensitivity, and hypertension: human NEDD4L rs4149601 G allele generates evolutionary new isoform I with C2 domain.2014
- Author(s)
  Ishigami T, Araki N、Minegishi S, Umemura M, Umemura S.
- Journal Title
  
  Journal of Hypertension
  
  Volume: 32(9) Issue: 9 Pages: 1905-1905
- DOI
  10.1097/hjh.0000000000000293
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461257
[Journal Article] Anti-interleukin-5 and multiple autoantibodies are associated with human atherosclerotic diseases and serum interleukin-5 levels2013
- Author(s)
  Ishigami T, Abe K, Aoki I, Minegishi S, Ryo A, Matsunaga S, Matsuoka K, Taleda H, Sawasaki T, Umemura S, Endoh Y.
- Journal Title
  
  FASEB J
  
  Volume: 27 Issue: 9 Pages: 3437-45
- DOI
  10.1096/fj.12-222653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591221, KAKENHI-PUBLICLY-25117719, KAKENHI-PROJECT-25290077
[Journal Article] Renin Angiotensin Antagonist Nromalize Aberrant Activation of Epithelial Sodium Channels in Sodium-Sensitive Hypertension2013
- Author(s)
  Hisako Uchio-Yamana, Shintaro Minegishi, Tomoaki Ishigami, et al.
- Journal Title
  
  Nephron Experimental Nephrology
  
  Volume: 122 Issue: 3-4 Pages: 95-102
- DOI
  10.1159/000348660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591221, KAKENHI-PROJECT-24591206
[Journal Article] Impact of renal insufficiency on long-term clinical outcome in patients with heart failure treated by cardiac resynchronization therapy2012
- Author(s)
  Hosoda J, Ishikawa T, Matsushita K, Matsumoto K, Kimura Y, Miyamoto M, Ogawa H, Takamura T, Sugano T, Ishigami T, Uchino K, Kimura K, Umemura S
- Journal Title
  
  J Cardiol
  
  Volume: 60(4)(Epub 2012 Jul 2)(PubMed PMID:22763383) Issue: 4 Pages: 301-5
- DOI
  10.1016/j.jjcc.2012.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591221
[Journal Article] Analysis of interferon-beta mRNA stability control after poly(I:C) stimulation using RNA metabolic labeling by ethynyluridine.2012
- Author(s)
  Abe K, Ishigami T, Shyu A. B, Ohno S, Umemura S, Yamashita A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 428(1) Issue: 1 Pages: 44-49
- DOI
  10.1016/j.bbrc.2012.09.144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PROJECT-23591221, KAKENHI-PROJECT-23687025, KAKENHI-PUBLICLY-23112718, KAKENHI-PLANNED-21115004
[Journal Article] Analysis of interferon-beta mRNA stability control after poly(I:C) stimulation using RNA metabolic labeling by ethynyluridine.2012
- Author(s)
  Kaito Abe, Tomoaki Ishigami, Ann-Bin Shyu, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 428 Pages: 44-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591221
[Journal Article] Intrarenal suppression of angiotensin II type 1 receptor binding molecule in angiotensin II-infused mice.2010
- Author(s)
  Wakui H, Ishigami T, et al.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Expression of angiotensin II type 1 receptor-interacting molecule in normal human kidney and IgA nephropathy.2010
- Author(s)
  Masuda S, Ishigami T, et al.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Cardiac-specific activation of angiotensin II type 1 receptor-associated protein completely suppresses cardiachypertrophy in chronic angiotensin II-infused mice.2010
- Author(s)
  Wakui H, Ishigami T, et al.
- Journal Title
  
  Hypertension.
  
  Volume: 55(5) Pages: 1157-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Expression of angiotensin II type 1 receptor-interacting molecule in normal human kidney and IgA nephropathy.2010
- Author(s)
  Masuda S, Tamura K, Wakui H, Maeda A, Dejima T, Hirose T, Toyoda M, Azuma K, Ohsawa M, Kanaoka T, Yanagi M, Yoshida S, Mitsuhashi H, Matsuda M, Ishigami T, Toya Y, Suzuki D, Nagashima Y, Umemura S.
- Journal Title
  
  Am J Physiol Renal Physiol. 299(4)
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Cardiac-specific activation of angiotensin II type 1 receptor-associated protein completely suppresses cardiac hypertrophy in chronic angiotensin II-infused mice.2010
- Author(s)
  Wakui H, Tamura K, Tanaka Y, Matsuda M, Bai Y, Dejima T, Masuda S, Shigenaga A, Maeda A, Mogi M, Ichihara N, Kobayashi Y, Hirawa N, Ishigami T, Toya Y, Yabana M, Horiuchi M, Minamisawa S, Umemura S.
- Journal Title
  
  Hypertension 55(5)
  
  Pages: 1157-1164
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Human Nedd4L rs4149601 G allele generates evolutionary new isoform I with C2 domain.2010
- Author(s)
  Ishigami T, Araki N, Umemura S.
- Journal Title
  
  Hypertension 55(2)
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Intrarenal suppression of angiotensin II type 1 receptor binding molecule in angiotensin II-infused mice.2010
- Author(s)
  Wakui H, Tamura K, Matsuda M, Bai Y, Dejima T, Shigenaga A, Masuda S, Azuma K, Maeda A, Hirose T, Ishigami T, Toya Y, Yabana M, Minamisawa S, Umemura S.
- Journal Title
  
  Am J Physiol Renal Physiol. 299(5)
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Utility and feasibility of a new programmable home blood pressure monitoring device for the assessment of nighttime blood pressure.2009
- Author(s)
  Ushio H, Ishigami T, Araki N, Minegishi S, Tamura K, Okano Y, Uchino K, Tochikubo O, Umemura S.
- Journal Title
  
  ClinExp Nephrol. 13(5)
  
  Pages: 480-485
- NAID
  10027226625
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Utility and feasibility of a new programmable home blood pressure monitoring device for the assessment of nighttime blood pressure2009
- Author(s)
  Ushio H, Ishigami T, et al.
- Journal Title
  
  Clinical Experimental Nephrology 13(5)
  
  Pages: 480-485
- NAID
  10027226625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Effect of losartan on ambulatory short-term blood pressure variability and cardiovascular remodeling in hypertensive patients on hemodialysis.2009
- Author(s)
  Mitsuhashi H, Tamura K, Yamauchi J, Ozawa M, Yanagi M, Dejima T, Wakui H, Masuda S, Azuma K, Kanaoka T, Ohsawa M, Maeda A, Tsurumi-Ikeya Y, Okano Y, Ishigami T, Toya Y, Tokita Y, Ohnishi T, Umemura S.
- Journal Title
  
  Atherosclerosis 207(1)
  
  Pages: 186-190
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Combining chronic kidney disease with201thallium/123iodine beta methyliodophenyl pentadecanoic acid dual myocardial single-photon emission computed tomography findings is useful for the evaluation of cardiac event risk.2009
- Author(s)
  Takamura T, Takahashi N, Ishigami T, Sugano T, Ishikawa T, Uchino K, Kimura K, Inoue T, Umemura S.
- Journal Title
  
  Nucl Med Commun. 30(1)
  
  Pages: 54-61
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Effects of angiotensin II type 1 receptor blocker on blood pressure variability and cardiovascular remodeling in hypertensive patients on chronic peritoneal dialysis.2009
- Author(s)
  Shigenaga A, Tamura K, Dejima T, Ozawa M, Wakui H, Masuda S, Azuma K, Tsurumi-Ikeya Y, Mitsuhashi H, Okano Y, Kokuho T, Sugano T, Ishigami T, Toya Y, Uchino K, Tokita Y, Umemura S.
- Journal Title
  
  Nephron Clin Pract. 112(1)
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Blood pressure variability as well as blood pressure level is important for left ventricular hypertrophy and brachial-ankle pulse wave velocity in hypertensives.2009
- Author(s)
  Ozawa M, Tamura K, Okano Y, Matsushita K, Ikeya Y, Masuda S, Wakui H, Dejima T, Shigenaga A, Azuma K, Ishigami T, Toya Y, Ishikawa T, Umemura S.
- Journal Title
  
  Clin Exp Hypertens. 31(8)
  
  Pages: 669-679
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Urinary oxidative stress markers closely reflect the efficacy of candesartan treatment for diabetic nephropathy.2009
- Author(s)
  Yoshida, S, Ishigami, T, et al.
- Journal Title
  
  Nephron Exp Nephrolo 111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Identification of an increased short-term blood pressure variability on ambulatory blood pressure monitoring as a coronary risk factor in diabetic hypertensives.2009
- Author(s)
  Ozawa M, Tamura K, Okano Y, Matsushita K, Yanagi M, Tsurumi-Ikeya Y, Oshikawa J, Hashimoto T, Masuda S, Wakui H, Shigenaga A, Azuma K, Ishigami T, Toya Y, Ishikawa T, Umemura S.
- Journal Title
  
  Clin Exp Hypertens. 31(3)
  
  Pages: 259-270
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Left ventricular geometry, risk factors, and outcomes of hospitalized patients with diastolic heart failure in Japan.2009
- Author(s)
  Uchino K, Ishigami T, Ohshige K, Sugano T, Ishikawa T, Kimura K, Umemura S.
- Journal Title
  
  J Cardiol. 54(1)
  
  Pages: 101-107
- NAID
  10025184500
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Identification of an increased short-term blood pressure variability on ambulatory blood pressure monitoring as a coronary risk factor in diabetic hypertensives.2009
- Author(s)
  Ozawa, M, Ishigami, T, et. al.
- Journal Title
  
  Clin Exp Hypertens 31
  
  Pages: 259-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Identification of NPC2 protein as interaction molecule with C2 domain of human Nedd4L2009
- Author(s)
  Araki N, Ishigami T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 31(8)
  
  Pages: 669-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Combining chronic kidney disease with 201thallium/123iodine beta methlyiodophenly pentadecanoic acid dual myocardial single-photon emission computed tomography findings is useful for the evaluation of cardiac event risk.2009
- Author(s)
  Takamura, T, Ishigami, T, et al.
- Journal Title
  
  Nucl Med Commun 30
  
  Pages: 54-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Identification of NPC2 protein as interaction molecule with C2 domain of human Nedd4L.2009
- Author(s)
  Araki N, Ishigami T, Ushio H, Minegishi S, Umemura M, Miyagi Y, Aoki I, Morinaga H, Tamura K, Toya Y, Uchino K, Umemura S.
- Journal Title
  
  Biochem Biophys Res Commun. 388(2)
  
  Pages: 290-296
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Human Nedd4L rs4149601 G allele generates evolutionary new isoforml with C2 domain2009
- Author(s)
  Ishigami T, Araki N, Umemura
- Journal Title
  
  Hypertension 55(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590978
[Journal Article] Expression, transcription end possible dominant negative interaction of the human Nedd4L gene truncation variant; implications for EH2008
- Author(s)
  Araki, N, Ishigami, T, et. al.
- Journal Title
  
  Hypertension 51(3)
  
  Pages: 773-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Expression, transcription and possible dominant negative interaction of the human Nedd4L gene truncation variantimplications for EH2008
- Author(s)
  Araki N, Ishigami T(corresponding author), et. al.
- Journal Title
  
  Hypertension 51(3)
  
  Pages: 773-7
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Expression, transcription and possible dominant negative interaction of the human Nedd4L gene truncation variant: implications for EH2008
- Author(s)
  Araki N, Ishigami T(correspondingauthor), et. al.
- Journal Title
  
  Hypertension. 51(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Novel Regulatory Effect ofAngiotsnsin II Type 1 Receptor Interacting Molecule on Vascular Smooth Muscle Cells2007
- Author(s)
  Azuma, K, Ishigami, T, et. al.
- Journal Title
  
  Hypertension
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] A possible relationship of nocturnal blood pressure variability・・・2007
- Author(s)
  Tamura K, Ishigami T, et al.
- Journal Title
  
  Clin Exp Hypertens. 29(1)
  
  Pages: 31-42
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Novel Regulatory Effect of Angiotensin II Type 1 Receptor Interacting Molecule on Vascular Smooth Muscle Cells2007
- Author(s)
  Azuma K, Ishigami T, et. al.
- Journal Title
  
  Hypertension. 50(5)
  
  Pages: 926-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Expression of MAK-V/Hunk in Renal Distal Tubles and Its Possibe・・・2007
- Author(s)
  Sakai M, Ishigami T, et al.
- Journal Title
  
  Am J Physiol Renal Phsiol, Epub ahead
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] NEDD4L protein truncating variant (v131G/A):rs4149601 is associated with essential hypertension EH in a sample of the Japanese population2007
- Author(s)
  Tomoaki, Ishigami, et. al.
- Journal Title
  
  Geriatrics Gerontology International 7, 2
  
  Pages: 125-128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Novel Regulatory Effect of Angiotensin II Type 1 Receptor Interacting Molecule on Vascular Smooth Muscle Cells2007
- Author(s)
  Azuma K, Ishigami T, et. al.
- Journal Title
  
  Hypertension 50(5)
  
  Pages: 926-32
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Adenosine concentration in great cardiac vein is increased・・・2006
- Author(s)
  Uchino K, Ishigami T, et al.
- Journal Title
  
  Heart and Vessels 21(4)
  
  Pages: 247-50
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] ARB or ACEI, that is the Question. Editorial Comment2006
- Author(s)
  Ishigami, T, et al.
- Journal Title
  
  Hypertension Research 29
  
  Pages: 837-838
- Data Source
  KAKENHI-PROJECT-18590898
[Journal Article] Daily Shock Impedance Measured by Implantable Cardioverter・・・2006
- Author(s)
  Matsushita, K, Ishigami T, et al.
- Journal Title
  
  Circulation J 70(11)
  
  Pages: 1462-5
- Data Source
  KAKENHI-PROJECT-18590898
[Patent] Lubiprostoneの新規用途に関する特許出願2019
- Inventor(s)
  石上友章・荒川健太郎
- Industrial Property Rights Holder
  石上友章・荒川健太郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-049565
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K09730
[Presentation] Characteristics of CD117(c-kit) on cortical bone stem cells.2020
- Author(s)
  千葉由美、佐々木紀彦、世古卓也、石上友章、久保一
- Organizer
  第19回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18K19689
[Presentation] Evaluation of three-dimensional in vitro cell culture of cortical bone stem cells.2020
- Author(s)
  千葉由美、佐用かなえ、小島伸彦、石上友章、久保一
- Organizer
  第19回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18K19689
[Presentation] Lubiprostone as a Potential Therapeutic Agent to Improve Intestinal2019
- Author(s)
  Kentaro Arakawa, Tomoaki Ishigami, et al
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-17K09730
[Presentation] 8週齢・48週齢の心筋梗塞モデルマウスの心機能の経時的変化2018
- Author(s)
  世古卓也, 千葉由美, 峯岸慎太郎, 石上友章
- Organizer
  第5回日本血管血流学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19689
[Presentation] カフ・オシロメトリック法による血圧・血管指標の測定値に与える、繰り返しカフ圧負荷の影響についての検討2018
- Author(s)
  織井　隆介、石上　友章、土肥　宏志、寺中　紗絵、木野　旅人、中島　理恵、杉山　美智子、峯岸　慎太郎、安部　開人、田村　功一
- Organizer
  第41回日本高血圧学会
- Data Source
  KAKENHI-PROJECT-17K09730
[Presentation] Practice for Dysphagic Patients with Cardiac Operation : Literature Review2018
- Author(s)
  Chiba Y, Ohashi N, Watanabe Y, Motohashi K, Tohara H, Nohara K, Nakayama E, Minegishi S, Ishigami T, Yamada R, Ichimura K, Nito T.
- Organizer
  The 3rd Japan-Korea Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04458
[Presentation] カフ・オシロメトリック法による中心血圧の測定による心機能評価の可能性2018
- Author(s)
  寺中　紗絵、石上　友章、土肥　宏志、木野　旅人、峯岸　慎太郎、中島　理恵、荒川　健太郎、杉山　美智子、石川　利之、田村　功一
- Organizer
  第41回日本高血圧学会
- Data Source
  KAKENHI-PROJECT-17K09730
[Presentation] マウス皮質骨由来幹細胞の膜表面蛋白と分化の特徴2018
- Author(s)
  千葉由美, 世古卓也, 石原賢司, 加藤智美, 中島理恵, 杉山美智子, 村松さやか, 豊田雅士, 石上友章, Hajime Kubo
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K19689
[Presentation] Regulations of ENaC Expressions by Nedd4L and tubular Renin-angiotensin Systems2018
- Author(s)
  石上友章
- Organizer
  日本生理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09730
[Presentation] 食塩と血圧と私―一周まわって知らない話。2018
- Author(s)
  石上友章
- Organizer
  第41回日本高血圧学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09730
[Presentation] Lubiprostone as a Potential Therapeutic Agent to Improve Intestinal Permeability and Prevent the Development of Atherosclerosis in ApoE KO mice2018
- Author(s)
  Kentaro Arakawa, Tomoaki Ishigami, et al.
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09730
[Presentation] Hypothesis Driven Approachによる食塩感受性・高血圧の成因としてのENaC-Nedd4L/Nedd4-2系の役割の検討2016
- Author(s)
  石上友章
- Organizer
  第39回日本高血圧学会
- Place of Presentation
  仙台国際センター(宮城県）
- Year and Date
  2016-09-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461257
[Presentation] Nedd4-2 C2ノックアウトマウスを用いた心房細動の誘発に対する影響の検討2016
- Author(s)
  川村飛翔, 峯岸慎太郎, 木野旅人, 中島理恵, 陳琳, 土肥宏志, 杉山美智子, Rajesh Prajapati, 藤田孝之, 石川義弘, 千葉由美, 石上友章, 田村功一
- Organizer
  第20回日本心血管内分泌代謝学会学術集会
- Place of Presentation
  東京コンベンションホール（東京都中央区）
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-26671017
[Presentation] 降圧治療は"the lower, the better"か？2015
- Author(s)
  石上友章
- Organizer
  第4回臨床高血圧フォーラム
- Place of Presentation
  東京ステーションカンファレンス(東京都）
- Year and Date
  2015-05-14
- Invited
- Data Source
  KAKENHI-PROJECT-26461257
[Presentation] 糖尿病合併高血圧の第一選択薬はARBか？2015
- Author(s)
  石上友章
- Organizer
  第38回日本高血圧学会
- Place of Presentation
  愛媛県松山市ひめぎんホール(愛媛県）
- Year and Date
  2015-10-11
- Invited
- Data Source
  KAKENHI-PROJECT-26461257
[Presentation] Nedd4L および尿細管レニン - アンジオテンシン系を介した ENaC 発現機能制御～食塩感受性におけるその意義2014
- Author(s)
  石上友章、梅村将就、新城名保美、峯岸慎太郎、山名比早子
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Invited
- Data Source
  KAKENHI-PROJECT-23591221
[Presentation] Nedd4Lおよび尿細管レニン・アンジオテンシン系を介したENaC発現機能制御～食塩感受性におけるその意義2014
- Author(s)
  石上友章、梅村将就、新城名保美、峯岸慎太郎、山名比早子
- Organizer
  第91回日本生理学会大会シンポジウム3
- Place of Presentation
  鹿児島
- Year and Date
  2014-03-16
- Invited
- Data Source
  KAKENHI-PROJECT-23591221
[Presentation] 上皮型Naチャネルのユビキチン化翻訳後制御と腎高血圧疾患についての検討2014
- Author(s)
  石上友章
- Organizer
  第35回日本臨床薬理学会学術総会
- Place of Presentation
  ひめぎんホール（愛媛県）
- Year and Date
  2014-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-26461257
[Presentation] Nedd4L および尿細管レニン - アンジオテンシン系を介した ENaC 発現機能制御～食塩感受性におけるその意義2014
- Author(s)
  石上友章、梅村将就、新城名保美、峯岸慎太郎、山名比早子
- Organizer
  第91回日本生理学会大会シンポジウム３
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-23591221
[Presentation] Nedd4Lおよび尿細管レニン・アンジオテンシン系を介したENaC発現機能制御～食塩感受性におけるその意義2014
- Author(s)
  石上友章ほか
- Organizer
  第134回日本薬学会
- Place of Presentation
  熊本
- Year and Date
  2014-03-30
- Invited
- Data Source
  KAKENHI-PROJECT-23591221
[Presentation] 糖尿病合併高血圧の第一選択薬にカルシウム拮抗薬　ディベート2014
- Author(s)
  石上友章
- Organizer
  第36回日本高血圧学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2014-10-21
- Invited
- Data Source
  KAKENHI-PROJECT-26461257
[Presentation] Nedd4L with C2 domain protein is critical for renal and cardiovascular adaptations to oral sodium intake-Experiments using Nedd4L C2 knockout mice.2012
- Author(s)
  Shintaro Minegishi, Tomoaki Ishigami, et al.
- Organizer
  ISHR 29th, 2012
- Place of Presentation
  九州大学医学部百年講堂（福岡県）
- Data Source
  KAKENHI-PROJECT-23591221
[Presentation] Differences among renin-angiotensin system blockade for the target organ damage and angiotensin II induced SCN5A-Nedd4L activation with mineralocorticoid receptor transactivaion in the model of sodium sensitive hypertension.2011
- Author(s)
  Minegishi S, Ishigami T, H Yamana, Umemura S.
- Organizer
  American Physiological Society
- Place of Presentation
  米国、カリフォルニア
- Data Source
  KAKENHI-PROJECT-23591221
[Presentation] ALDOSTERONE INDEPENDENT ACTIVATION OF MINERALCORTICOID RECEPTOR-SGK1 SYSTEMS IN URINARY EPITHELIUM FOR THE MODEL OF SODIUM SENSITIVE HYPERTENSION2010
- Author(s)
  Ushio H, Ishigami T, et al.
- Organizer
  第20回ヨーロッパ高血圧学会
- Place of Presentation
  Norway, Oslo
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-20590978
[Presentation] ANGIOTENSIN II INDUCED SCN5A-NEDD4L TRANSCRIPTIONAL ACTIVATION WITH MINERAL CORTICOID RECEPTOR TRANSACTIVATION IN CARDIOMYOCYTES2010
- Author(s)
  Minegishi S, Ishigami T, et al.
- Organizer
  第20回ヨーロッパ高血圧学会
- Place of Presentation
  Norway, Oslo
- Year and Date
  2010-06-20
- Data Source
  KAKENHI-PROJECT-20590978
[Presentation] ALDOSTERONE INDEPENDENT ACTIVATION OF MINERALCORTIC OID RECEPTOR-SGK1 SYSTEMS IN URINARY EPITHELIUM FOR THE MODEL OF SODIUM SENSITIVE HYPERTENSION2010
- Author(s)
  Ushio H, Ishigami T, et al.
- Organizer
  第20回ヨーロッパ高血圧学会
- Place of Presentation
  Norway, Oslo
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-20590978
[Presentation] A New Programmable Home Blood Pressure Monitoring Device For The Assessment of Night Time Blood Pressure of Total Of 40 Normotensive Subjects2010
- Author(s)
  石上友章, et al.
- Organizer
  第20回ヨーロッパ高血圧学会
- Place of Presentation
  Norway, Oslo
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20590978
[Presentation] A New Programmable Home Blood Pressure Monitoring Device For The Assessment of Night Time Blood Pressure of Total Of 40 Nromotensive Subjects2010
- Author(s)
  Ishigami T, et al.
- Organizer
  第20回ヨーロッパ高血圧学会
- Place of Presentation
  Norway, Oslo
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20590978
[Presentation] 本態性高血圧症の候補遺伝子としてのNedd4Lに関する検討2009
- Author(s)
  石上友章
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-20590978
[Presentation] Identifieetion of binding protein for human Nedd4L C2 domain2008
- Author(s)
  Naomi, Aralci, Tornoek, Ishigami, Masanari, Umetnura, Koichi, Tamura, Satoshi, Umernura
- Organizer
  International Society of Hypertension
- Place of Presentation
  Berlin, German
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590898
[Presentation] Identification of binding proteins for human Nedd4L C2 domain.2008
- Author(s)
  Araki, N, Ishigami, T, et al.
- Organizer
  22^<nd> International Society of Hypertension, Berlin, Germany
- Place of Presentation
  Berlin, Germany
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-20590978
[Presentation] Sodium sensitive hypertension and Nedd4L2007
- Author(s)
  Tomoaki, Ishigami, Masaaari, Umemura, Naomi, Araki, Koichi, Tamura ,Kazualki Uchino, Satosbi, Umemnra
- Organizer
  the 6th International Symposium on on "Aldosterone and ENaC from gene to disease"
- Place of Presentation
  Zermatt, Switaerlend
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590898
[Presentation] Sodium sensitive hypertension and Nedd4L2007
- Author(s)
  Ishigami T, et. al.
- Organizer
  6th International Symposium on "Aldosterone and ENaC: from gene to disease"
- Place of Presentation
  Zermatt, Switzerland
- Data Source
  KAKENHI-PROJECT-18590898

1. CHIBA Yumi (10313256)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. UMEMURA Satoshi (00128589)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 峯岸慎太郎 (80458398)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. SASAKI Norihiko (80639063)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 戸原玄 (00396954)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 野原幹司 (20346167)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 渡邊裕 (30297361)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 三枝祐輔 (30806469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 二藤隆春 (60334372)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 山田律子 (70285542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 大橋伸英 (70783752)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. 藤田孝之 (40468202)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
13. KIHARA Minoru (60177904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAGI Nobuyoshi (10163172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MURAKAMI Kazuo (70110517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAMURA Kouichi (40285143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. ITAKURA Yoko (30582746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 石井當男 (90010363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 豊田雅士 (50392486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 中山渕利 (10614159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 市村久美子 (00143149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 荒川健太郎 (00806747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 宮川繁 (70544237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 川上恭司郎 (90589227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 鈴木敦 (00625626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 藤野剛雄 (10721904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 内海桃絵 (40585973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 佐々木康之輔 (50755642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 吉田俊子 (60325933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 小西正紹 (60530152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 荒木田真子 (90932335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. NAKASHIMA Rie

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. WAKUI Hiromichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
34. YOKOYAMA Utako

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
35. 石川義弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
36. 梅村将就

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
37. 山下暁朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. 大野茂男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishigami Tomoaki 石上 友章

ISHIGAMI Tomoaki 石上 友章

Research Projects

Research Products

Co-Researchers

Development and effectiveness of an intervention programme for the systemic, swallowing and nutritional status of patients with severe cardiac disease.

Principal Investigator

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Review Section

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Effects of nutrition, aging, and stem cell against inflammation on high-risk heart disease, and evaluation of tissue regeneration ability.

Principal Investigator

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Review Section

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Elucidation for tubular mechanism for salt sensitivity and hypertension focusing of "Excitation-Transcription Coupling"Principal Investigator

Principal Investigator

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Review Section

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Elucidation for Molecular Pathophysiology of Atherosclerosis Focusing of Commensal Microbe and Splenic B2 Cells

Principal Investigator

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Review Section

Research Institution

Evaluation of effects on age and tissue regeneration by exercise intervention on high-risk myocardial infarction

Principal Investigator

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Review Section

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Salt Sensitivity, Hypertension and Tubular MechanismPrincipal Investigator

Principal Investigator

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Development and Evaluation of Rehabilitation Program depending on Patients with Severe Body and Dysphagic Conditions

Principal Investigator

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Elucidation and Expansion of Molecular Physiology of Salt Sensitivity and Hypertensin Based on Tubular Mechanism.Principal Investigator

Principal Investigator

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Influence of aging and exercise on engraftment after stem cell transplantation into myocardial infarction model mice

Principal Investigator

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Analyses of molecular mechanism of hypertensive cardio-renal relationships focusing on post-transcriptional regulations of ion-transporters.Principal Investigator

Principal Investigator

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Research Institution

Identifications for molecular mechanisms of essential hypertension in terms of urinary tubular ion transporter and human NEDD4L.Principal Investigator

Principal Investigator

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Research Institution

Molecular Pathopbysiological Reseatch of ubiquitin ligase,human Nodd4L, for the development ofessentialhyportensionPrincipal Investigator

Principal Investigator

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Research Institution

ヒト心臓キマーゼ遺伝子の循環器疾患における役割の検討Principal Investigator

Principal Investigator

Project Period (FY)

Ishigami Tomoaki 石上友章

ISHIGAMI Tomoaki 石上友章