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Kosaka Mitsuko  小阪 美津子

… Alternative Names

小阪 美津子  コサカ ミツコ

KOSAKA MITSUKO  小阪 美津子

KOSAKA Mitsuko  小阪 美津子

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Researcher Number 50270476
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-6146-5184
Affiliation (Current) 2022: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help 2019: 岡山大学, 医歯薬学総合研究科, 助教
2016: 岡山大学, 医歯薬学総合研究科, 助教
2015: 岡山大学, 医歯(薬)学総合研究科, 助教
2011 – 2013: 岡山大学, 医歯(薬)学総合研究科, 助教
2008: Okayama University, 医学部, 客員研究員
2007: The Institute of Physical and Chemical Research, 体性組織幹細胞研究ユニット, ユニットリーダー
1995 – 1996: 岡崎国立共同研究機構, 基礎生物学研究所, 助手
Review Section/Research Field
Principal Investigator
Ophthalmology / Developmental biology / General anatomy (including histology/embryology) / Basic Section 55040:Respiratory surgery-related
Except Principal Investigator
Developmental biology
Keywords
Principal Investigator
幹細胞 / がん / 網膜 / 発生 / 再生 / 分化転換 / 色素上皮細胞 / 脱分化 / 再分化 / レンズ再生 … More / 細胞分化 / 網膜変性疾患 / 視細胞 / cone / Oct3/4 / 転写調節因子 / 国際情報交換 / 組織幹細胞 / 体性組織 / 多分化能 / 体性組織幹細胞 / 可塑性 / 体細胞 / 転移 / 遺伝子発現制御 / ライブイメージング … More
Except Principal Investigator
再生 / 分化転換 / FGF / Transdifferentiation / 発生 / 遺伝子発現 / 水晶体 / イモリ / 加齢 / アフリカツメガエル / 網膜 / 遺伝発現 / 色素上皮 / レンズ / Development / Regeneration / Gene Expression / Lens / Newt / Aging / 脱分化 / 分化の安定化 / 色素上皮細胞 / 成長因子 / ホメオボックス遺伝子 / 遺伝子発現調節 / 細胞外基質 / 増殖因子 / 分化制御因子 / 脊椎動物 / Dedifferentiation / Stabilization in differentiation / Pigmented epithelial call / Growth factor / Homebox gene / Gene expression Less
  • Research Projects

    (7 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (9 People)
  •  転移の鍵をにぎるSPP1遺伝子発現制御機構の解明とその応用Principal Investigator

    • Principal Investigator
      小阪 美津子
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Okayama University
  •  Cellular plasticity of OCT4 expressing somatic cellsPrincipal Investigator

    • Principal Investigator
      KOSAKA MITSUKO
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Okayama University
  •  Role of Oct3/4 in retinal development and dieseasesPrincipal Investigator

    • Principal Investigator
      KOSAKA MITSUKO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  Key genes related to retinal development and diseasesPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
      The Institute of Physical and Chemical Research
  •  虹彩色素上皮細胞によるレンズ細胞への分化転換機構Principal Investigator

    • Principal Investigator
      小阪 美津子
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Developmental biology
    • Research Institution
      Okazaki National Research Institutes
  •  Molecular Mechanism of Transdifferentiation in Regeneration

    • Principal Investigator
      KODAMA Ryuji, EGUCHI Goro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Developmental biology
    • Research Institution
      Okazaki National Research Institutes
  •  Molecular Mechanisms of Transdifferentiation and Stabilization in Differentiation of Animal Tissue Cells

    • Principal Investigator
      EGUCHI Goro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      National Institute for Basic Biology (NIBB), Okazaki National Research Institutes

All 2017 2016 2015 2014 2013 2011 2008 2007

All Journal Article Presentation Patent

  • [Journal Article] Immediate differentiation of neuronal cells from stem/progenitor-like cells in the avian iris tissues2014

    • Author(s)
      T. Matsushita, A. Fujihara, L. Royall, S. Kagiwada, M. Kosaka and M. Araki
    • Journal Title

      Exp Eye Res

      Volume: 123 Pages: 16-26

    • DOI

      10.1016/j.exer.2014.04.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22124001, KAKENHI-PROJECT-23592606
  • [Journal Article] Architecture of the subendothelial elastic fibers of small blood vessels and variations in vascular type and size2013

    • Author(s)
      Akira Shinaoka
    • Journal Title

      Microsc Microanal.

      Volume: 19 Pages: 406-14

    • DOI

      10.1017/s1431927612014341

    • NAID

      120005359113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591542, KAKENHI-PROJECT-23390348, KAKENHI-PROJECT-23592606, KAKENHI-PROJECT-24700531
  • [Journal Article] Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled42011

    • Author(s)
      Ohta K, Ito A, Kuriyama S, Lupo G, Kosaka M, Ohnuma S, Nakagawa S, Tanaka H
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 108(36) Pages: 14962-7

    • DOI

      10.1073/pnas.1100513108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592606
  • [Journal Article] /Iris pigment epithelium as a potential source for both basic biology and therapeutic applications for retinal regeneration/2008

    • Author(s)
      Mitsuko Kosaka
    • Journal Title

      Strategies for Retinal Tissue Repair and Regeneration in Vertebrates:From Fish to Human

      Pages: 139-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Journal Article] Novel variants of Oct-3/4 gene expressed in mouse somatic cells2008

    • Author(s)
      Mizuno, N and Kosaka, M.
    • Journal Title

      Journal of Biological Chemistry 283

      Pages: 30997-31004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Journal Article] Iris pigment epithelium as a potential source for both basic biology and therapeutic applications for retinal regeneration2008

    • Author(s)
      Mitsuko, Kosaka
    • Journal Title

      Strategies for retinal tissue repair and regeneration in vertebnrates : From fish to human

      Pages: 139-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Journal Article] Novel variants of Oct-3/4 gene expressed in mouse somatic cells.2008

    • Author(s)
      Mizuno N, Kosaka M
    • Journal Title

      Journal of Biological Chemistry 283

      Pages: 30997-31004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Journal Article] Multipotent cells from mammalian iris pigment epithelium2007

    • Author(s)
      Asami, M, Sun, GW, Yamaguchi, M, Kosaka, M.
    • Journal Title

      Developmental Biology 304

      Pages: 433-446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Journal Article] Multipotent cells from mammalian iris pigment epithelium2007

    • Author(s)
      Asami Sun Yamaguchi Kosaka
    • Journal Title

      Developmental Biology 304

      Pages: 433-446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Patent] 癌検出キット、および、癌診断のためのデータの取得方法2016

    • Inventor(s)
      小阪美津子、水野伸彦
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-073956
    • Filing Date
      2016-03-31
    • Data Source
      KAKENHI-PROJECT-15K15016
  • [Presentation] 虹彩および網膜に存在する組織幹細胞の実態2017

    • Author(s)
      小阪美津子, 大塚愛二
    • Organizer
      第122回日本解剖学会総会・学術集会 シンポジウム講演
    • Place of Presentation
      長崎大学
    • Year and Date
      2017-03-28
    • Data Source
      KAKENHI-PROJECT-15K15016
  • [Presentation] ヒトPOU5F1 遺伝子ヴァリアントがコードするOCT4Cタンパク質の特性2017

    • Author(s)
      上園深希, 戎井孝太, 水野伸彦, 小阪美津子, 大塚愛二
    • Organizer
      第122回日本解剖学会総会・学術集会 一般演題
    • Place of Presentation
      長崎大学
    • Year and Date
      2017-03-28
    • Data Source
      KAKENHI-PROJECT-15K15016
  • [Presentation] ヒトOct4遺伝子とOct4偽遺伝子の機能的差異2015

    • Author(s)
      戎井孝太、大前凌、水野伸彦、小阪美津子、大塚愛二
    • Organizer
      日本解剖学会第70回中国・四国支部学術集会
    • Place of Presentation
      愛媛大学
    • Year and Date
      2015-10-24
    • Data Source
      KAKENHI-PROJECT-15K15016
  • [Presentation] ヒト癌細胞で発現するOct3/4遺伝子variantの同定2013

    • Author(s)
      宮本朋幸、水野伸彦、大野英治、大塚愛二、小阪美津子
    • Organizer
      第118回日本解剖学会全国学術集会
    • Place of Presentation
      サンポート高松、香川
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-23592606
  • [Presentation] 体性組織で発現するOct3/4遺伝子variantの機能解析2013

    • Author(s)
      三宅望、高畠あゆむ、水野伸彦、小阪美津子、大塚愛二
    • Organizer
      第118回日本解剖学会全国学術集会
    • Place of Presentation
      サンポート高松、香川
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23592606
  • [Presentation] マウスOct3/4遺伝子variantがコードするOct3/4C蛋白質の性状解析2013

    • Author(s)
      入江恭平、水野伸彦、小阪美津子、大塚愛二
    • Organizer
      第118回日本解剖学会全国学術集会
    • Place of Presentation
      サンポート高松、香川
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23592606
  • [Presentation] マウスOct3/4遺伝子variantがコードするOCT3/4Cタンパク質の性状解析2013

    • Author(s)
      入江恭平、水野伸彦、小阪美津子、大塚愛二
    • Organizer
      第118回日本解剖学会全国学術集会
    • Place of Presentation
      サンポート高松、香川
    • Data Source
      KAKENHI-PROJECT-23592606
  • [Presentation] ヒトOct4遺伝子発現解析における問題点の克服2013

    • Author(s)
      宮本朋幸、小阪美津子、水野伸彦、大野英治、大塚愛二
    • Organizer
      第68回日本解剖学会中四国支部学術集会
    • Place of Presentation
      鳥取大学医学部米子キャンパス
    • Data Source
      KAKENHI-PROJECT-23592606
  • [Presentation] ヒトOct4遺伝子発現解析における問題点の克服2013

    • Author(s)
      宮本朋幸、小阪美津子、水野伸彦、大野英治、大塚愛二
    • Organizer
      鳥取大学医学部
    • Place of Presentation
      鳥取
    • Year and Date
      2013-10-19
    • Data Source
      KAKENHI-PROJECT-23592606
  • [Presentation] 組織幹細胞の実体解明から癌幹細胞研究への新展開2008

    • Author(s)
      小阪美津子
    • Organizer
      第2回産学官連携新産業創出研究会「大腸癌幹細胞の生物学的特性の解析と新癌治療法の開発」研究会
    • Place of Presentation
      岡山
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Presentation] 体細胞のフレキシビリティの理解と応用2008

    • Author(s)
      小阪美津子
    • Organizer
      第35回日本臓器保存生物医学定期学術集会シンポジウム講演
    • Place of Presentation
      東京
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Presentation] 体細胞のフレキシビリティの理解と応用2008

    • Author(s)
      小阪 美津子
    • Organizer
      第35回日本臓器保存生物医学定期学術集会 (シンポジウム講演
    • Place of Presentation
      東京都六本木ヒルズ
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Presentation] 眼組織幹細胞としての虹彩上皮細胞の基礎と応用2007

    • Author(s)
      小阪美津子
    • Organizer
      第34回日本臓器保存生物医学定期学術集会シンポジウム講演
    • Place of Presentation
      北海道
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Presentation] Developmental plasticity of cone-photoreceptor precursor cells in postnatal mouse retina2007

    • Author(s)
      Watanabe, Asami, Sun, Tsuchida, Kosaka
    • Organizer
      第40回日本発生生物・細胞生物学会合同大会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2007-05-28
    • Data Source
      KAKENHI-PROJECT-19592048
  • [Presentation] Developmental plasticity of cone-photoreceptor precursor cells in postnatal mouse retina2007

    • Author(s)
      渡邉康行、浅見真紀、孫こうい、土田順二、小阪美津子
    • Organizer
      第40回日本発生生物・細胞生物学会合同大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-28
    • Data Source
      KAKENHI-PROJECT-19592048
  • 1.  EGUCHI Goro (80022581)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  MIZUNO Nobuhiko (60462735)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 3.  KODAMA Ryuji (90161950)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MOCHII Makoto (90202358)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TSONIS Panagiotis
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  OHTUKA Aiji (50168986)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 7.  MOMOTA Ryusuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  SHINAOKA Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  熊岸 加苗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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