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hasegawa minoru  長谷川 稔

… Alternative Names

Hasegawa Minoru  長谷川 稔

HASEGAWA Minoru  長谷川 稔

長谷川 稔  ハセカ゛ワ ミノル

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Researcher Number 50283130
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-3738-2682
External Links
Affiliation (Current) 2025: 福井大学, 学術研究院医学系部門, 教授
Affiliation (based on the past Project Information) *help 2019 – 2023: 福井大学, 学術研究院医学系部門, 教授
2016 – 2017: 福井大学, 学術研究院医学系部門, 教授
2013 – 2015: 福井大学, 医学部, 教授
2011 – 2012: 金沢大学, 大学病院, 講師
2009 – 2011: Kanazawa University, 附属病院, 講師 … More
2006 – 2007: 金沢大学, 医学部附属病院, 講師
2003 – 2004: 金沢大学, 医学部附属病院, 講師
2002: 金沢大学, 医学部附属病院, 助手
2001: 金沢大学, 医学部・附属病院, 助手
2000: Kanazawa University School of Medicine, Assistant Professor, 医学部・附属病院・皮膚科, 助手
1998: 金沢大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Basic Section 53050:Dermatology-related / Dermatology
Except Principal Investigator
Dermatology / Dermatology
Keywords
Principal Investigator
強皮症 / 線維化 / サイトカイン / 治療 / 血管障害 / 内皮間葉移行 / 治療薬 / CD20 / Tight skin mouse / マウス … More / 皮膚 / B細胞 / ケモカイン / 全身性強皮症 / 上皮間葉移行 / 化合物 / マウスモデル / 動物モデル / マクロファージ / 疾患モデル / 新規治療 / CX3CL1 / autoimmunity / fibrosis / cytokine / aintbody-therapy / B cell / systemic sclerosis / 自己抗体 / 自己免疫 / 抗体治療 / Th17 / IL-17 / CXCL8 / ICOS ligand / 肺 / ブレオマイシン / ICOSL / ICOS / ノックアウトマウス / 補体 / 細菌感染 / 肺炎連鎖球菌 / 35 / CD21 / interleukin 18 / Fractalkine / CX_3CR1 / fractalkine … More
Except Principal Investigator
ICAM-1 / tight skin mouse 1 / CD22 / CD19 / 全身性強皮症 / B細胞 / マウス胎仔 / 末梢血液 / 間葉系幹細胞 / 遺伝子治療 / マウス胎仔治療 / L-selectin / Arthus reaction / vasculitis / Cell adhesion molecule / E-selectin / P-selectin / Immune complex / 好中球 / 肥満細胞 / ノックアウトマウス / 血管炎 / L-セレクチン / P-セレクチン / E-セレクチン / 細胞接着分子 / 免疫複合体 / アルサス反応 / animal model / autoimmunity / B lymphocytes / systemic sclerosis / tight skin mouse I / 動物モデル / 自己免疫 / 制御性B細胞 / IL-10 Less
  • Research Projects

    (12 results)
  • Research Products

    (51 results)
  • Co-Researchers

    (8 People)
  •  内皮間葉移行阻害薬の探索と強皮症治療への応用Principal Investigator

    • Principal Investigator
      長谷川 稔
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      University of Fukui
  •  Could epithelial-mesenchymal transition inhibitors be a novel treatment for systemic sclerosis?Principal Investigator

    • Principal Investigator
      Hasegawa Minoru
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      University of Fukui
  •  Development of a novel therapy using anti-CX3CL1 antibody in systemic sclerosisPrincipal Investigator

    • Principal Investigator
      Hasegawa Minoru
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      University of Fukui
  •  Establishment of the novel embryonic cure system for an intractable skin disease mouse model by using a mesenchymal stem cells from the circulation blood of mouse embryo

    • Principal Investigator
      Chino Takenao
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      University of Fukui
  •  Cytokine-targeted therapy of sclerodermaPrincipal Investigator

    • Principal Investigator
      HASEGAWA Minoru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      University of Fukui
      Kanazawa University
  •  The role of regulatory B cell in systemic sclerosis and cytokine-induced fibrosis models

    • Principal Investigator
      TAKEHARA KAZUHIKO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  Investigation and therapeutic application of ICOS and ICOSL in systemic sclerosisPrincipal Investigator

    • Principal Investigator
      HASEGAWA Minoru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  B cell depletion therapy for the model mouse of sclerodermaPrincipal Investigator

    • Principal Investigator
      HASEGAWA Minoru
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  CD21/35欠損マウスの作成と解析Principal Investigator

    • Principal Investigator
      長谷川 稔
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  Relative contribution of various adhesion molecules to tissue injury induced by immune complex deposition

    • Principal Investigator
      SATO Shinichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  全身性強皮症とそのモデルマウスにおけるサイトカインおよびケモカインの関与Principal Investigator

    • Principal Investigator
      長谷川 稔
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  Development of the new animal model for systemic sclerosis using the immunologic function of CD19 and CD22

    • Principal Investigator
      SATO Shinichi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University

All 2022 2021 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2007 2006

All Journal Article Presentation

  • [Journal Article] The compound LG283 inhibits bleomycin-induced skin fibrosis via antagonizing TGF-β signaling2022

    • Author(s)
      Utsunomiya A, Hasegawa M, et al.
    • Journal Title

      Arthritis Research and Therapy

      Volume: 24 Issue: 1 Pages: 94-94

    • DOI

      10.1186/s13075-022-02773-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08769, KAKENHI-PROJECT-21K08321, KAKENHI-PROJECT-20K17313
  • [Journal Article] The clinical characteristics of juvenile-onset systemic sclerosis in Japanese patients.2014

    • Author(s)
      Hatta Y, Hasegawa M, Matsushita T, Hamaguchi Y, Fujimoto M, Takehara K.
    • Journal Title

      Mod Rheumatol.

      Volume: 24 Issue: 2 Pages: 377-9

    • DOI

      10.3109/14397595.2013.854073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] A crucial role of L-selectin in C protein-induced experimental polymyositis of mice.2014

    • Author(s)
      Oishi K, Hamaguchi Y, Matsushita T, Hasegawa M, Okiyama N, Dernedde J, Weinhart M, Haag R, Tedder TF, Takehara K, Kohsaka H, Fujimoto M.
    • Journal Title

      Arthritis Rheumatol.

      Volume: mar 18 Issue: 7 Pages: 1864-71

    • DOI

      10.1002/art.38630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-25461686
  • [Journal Article] Serum adhesion molecule levels as prognostic markers in patients with early systemic sclerosis: a multicentre, prospective, observational study.2014

    • Author(s)
      Hasegawa M, Asano Y, Endo H, Fujimoto M, Goto D, Ihn H, Inoue K, Ishikawa O, Kawaguchi Y, Kuwana M, Ogawa F, Takahashi H, Tanaka S, Sato S, Takehara K.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 2 Pages: e88150-e88150

    • DOI

      10.1371/journal.pone.0088150

    • NAID

      120006986537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Serum adhesion molecule levels as prognostic markers in patients with early systemic sclerosis: a multicentre, prospective, observational study.2014

    • Author(s)
      Minoru Hasegawa, Yoshihide Asano, Hirahito Endo, Manabu Fujimoto, Daisuke Goto, Hironobu Ihn, Katsumi Inoue, Osamu Ishikawa, Yasushi Kawaguchi. Masataka Kuwana, Fumihide Ogawa, Hiroki Takahashi, Sumiaki Tanaka, Shinichi Sato, Kazuhiko Takehara
    • Journal Title

      PLoS One

      Volume: 9

    • NAID

      120006986537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591644
  • [Journal Article] Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement.2014

    • Author(s)
      Kaji K, Fertig N, Medsger TA Jr, Satoh T, Hoshino K, Hamaguchi Y, Hasegawa M, Lucas M, Schnure A, Ogawa F, Sato S, Takehara K, Fujimoto M, Kuwana M.
    • Journal Title

      Arthritis Care Res

      Volume: 66 Issue: 4 Pages: 575-84

    • DOI

      10.1002/acr.22163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-26461471
  • [Journal Article] Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease.2013

    • Author(s)
      Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, Takehara K, Tedder TF, Fujimoto M.
    • Journal Title

      Blood

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease2013

    • Author(s)
      Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, T akehara K, T edder TF, Fujimoto M
    • Journal Title

      Blood

      Volume: 121 Issue: 16 Pages: 3274-83

    • DOI

      10.1182/blood-2012-11-465658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-23791260, KAKENHI-PROJECT-24659523
  • [Journal Article] FTY720 ameliorates murine Scl-cGVHD by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin.2013

    • Author(s)
      Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, Takehara K, Fujimoto M.
    • Journal Title

      Arthritis Rheum

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Serum chemokine levels as prognostic markers in patients with early systemic sclerosis: a multicenter, prospective, observational study2013

    • Author(s)
      Hasegawa M
    • Journal Title

      Mod Rheumatol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591644
  • [Journal Article] Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort.2013

    • Author(s)
      Fujimoto M
    • Journal Title

      Ann Rheum Dis

      Volume: 72 Issue: 1 Pages: 151-153

    • DOI

      10.1136/annrheumdis-2012-201736

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591245, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-23791260, KAKENHI-PROJECT-25461672
  • [Journal Article] Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort.2013

    • Author(s)
      Fujimoto M, Matsushita T, Hamaguchi Y, Kaji K, Asano Y, Ogawa F, Yamaoka T, Fujikawa K, Tsukada T, Sato K, Echigo T, Hasegawa M, Takehara K.
    • Journal Title

      Ann Rheum Dis.

      Volume: 72 Pages: 151-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] FTY720 ameliorates murine Scl-cGVHD by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin2013

    • Author(s)
      Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, Takehara K, Fujimoto M
    • Journal Title

      Arthritis Rheum

      Volume: in press Issue: 6 Pages: 1624-35

    • DOI

      10.1002/art.37933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-24659523, KAKENHI-PROJECT-25461686
  • [Journal Article] High incidence of pulmonary arterial hypertension in systemic sclerosis patients with anti-centriole autoantibodies2013

    • Author(s)
      Hamaguchi Y, Matsushita T, Hasegawa M, Ueda-Hayakawa I, Sato S, Takehara K, Fujimoto M
    • Journal Title

      Mod Rheumatol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Dermokine inhibits ELR(+)CXC chemokine expression and delays early skin wound healing.2013

    • Author(s)
      Hasegawa M, Higashi K, Matsushita T, Hamaguchi Y, Saito K, Fujimoto M, Takehara K.
    • Journal Title

      J Dermatol Sci.

      Volume: 70 Issue: 1 Pages: 34-41

    • DOI

      10.1016/j.jdermsci.2013.01.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] BLNK expression contributes to controlling allergic and autoimmune diseases by mediating IL-10 production in regulatory B cells2013

    • Author(s)
      Jin G, Hamaguchi Y, Matsushita T, Hasegawa M, Huu DL, Ishiura N, Naka K, Hirao A, Takehara K, Fujimoto M
    • Journal Title

      J Allergy Clin Immunol

      Volume: 131 Issue: 6 Pages: 1674-1682

    • DOI

      10.1016/j.jaci.2013.01.044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-23791260
  • [Journal Article] Potential roles of interleukin-17A in the development of skin fibrosis in mice.2012

    • Author(s)
      Okamoto Y, Hasegawa M
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 3726-3735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591644
  • [Journal Article] Potential roles of interleukin 17A in the development of skin fibrosis.2012

    • Author(s)
      Okamoto Y, Hasegawa M, Matsushita T, Hamaguchi Y, Huu DL, Iwakura Y, Fujimoto M, Takehara K.
    • Journal Title

      Arthritis Rheum.

      Volume: 64 Pages: 3726-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Potential roles of interleukin 17A in the development of skin fibrosis2012

    • Author(s)
      Okamoto Y, Hasegawa M, Matsushita T, Hamaguchi Y, Huu DL, Iwakura Y, Fujimoto M, T akehara K
    • Journal Title

      Arthritis Rheum

      Volume: 64 Issue: 11 Pages: 3726-35

    • DOI

      10.1002/art.34643

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-24220011
  • [Journal Article] Association of UBE2L3 polymorphisms with diffuse cutaneous systemic sclerosis in a Japanese population.2012

    • Author(s)
      Hasebe N, Kawasaki A, Ito I, Kawamoto M, Hasegawa M, Fujimoto M, Furukawa H, Tohma S, Sumida T, Takehara K, Sato S, Kawaguchi Y, Tsuchiya N.
    • Journal Title

      Ann Rheum Dis.

      Volume: 71 Pages: 1259-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Host-derived MCP-1 and MIP-1αregulate protective anti-tumor immunity to localized and metastatic B16 melanoma2012

    • Author(s)
      Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
    • Journal Title

      Am J Pathol

      Volume: 180(1) Issue: 1 Pages: 365-74

    • DOI

      10.1016/j.ajpath.2011.09.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Investigation of prognostic factors for skin sclerosis and lung function in Japanese patients with early systemic sclerosis: a multicentre prospective observational study.2012

    • Author(s)
      Hasegawa M
    • Journal Title

      Rheumatology

      Volume: 51 Pages: 129-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Investigation of prognostic factors for skin sclerosis and lung function in Japanese patients with early systemic sclerosis: a multicentre prospective observational study.2012

    • Author(s)
      Hasegawa M, Asano Y, Endo H, Fujimoto M, Goto D, Ihn H, Inoue K, Ishikawa O, Kawaguchi Y, Kuwana M, Muro Y, Ogawa F, Sasaki T, Takahashi H, Tanaka S, Takehara K, Sato S.
    • Journal Title

      Rheumatology (Oxford)

      Volume: 51 Issue: 1 Pages: 129-133

    • DOI

      10.1093/rheumatology/ker333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591618, KAKENHI-PROJECT-23591640
  • [Journal Article] Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins2012

    • Author(s)
      Fujimoto M, Hamaguchi Y, Kaji K, Matsushita T, Ichimura Y, Kodera M, Ishiguro N, Ueda-Hayakawa I, Asano Y, Ogawa F, Fujikawa K, Miyagi T, Mabuchi E, Hirose K, Akimoto N, Hatta N, Tsutsui K, Higashi A, Igarashi A, Seishima M, Hasegawa M, Takehara K
    • Journal Title

      Arthritis Rheum

      Volume: 64(2) Issue: 2 Pages: 513-22

    • DOI

      10.1002/art.33403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-24590185
  • [Journal Article] Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies : possible association with malignancy2012

    • Author(s)
      Ichimura Y, Matsushita T, Hamaguchi Y, Kaji K, Hasegawa M, Tanino Y, Inokoshi Y, Kawai K, Kanekura T, Habuchi M, Igarashi A, Sogame R, Hashimoto T, Koga T, Nishino A, Ishiguro N, Sugimoto N, Aoki R, Ando N, Abe T, Kanda T, Kuwana M, Takehara K, Fujimoto M
    • Journal Title

      Ann Rheum Dis

      Volume: 71(5) Issue: 5 Pages: 710-3

    • DOI

      10.1136/annrheumdis-2011-200697

    • NAID

      120004442395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-23791260
  • [Journal Article] Use of serum clara cell 16-kDa (CC16) levels as a potential indicator of active pulmonary fibrosis in systemic sclerosis2011

    • Author(s)
      Hasegawa M, Fujimoto M, Hamaguchi Y, Matsushita T, Inoue K, Sato S, Takehara K
    • Journal Title

      J Rheumatol

      Volume: 38(5) Issue: 5 Pages: 877-84

    • DOI

      10.3899/jrheum.100591

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Association between nail-fold capillary findings and disease activity in dermatomyositis2011

    • Author(s)
      Mugii N, Hasegawa M, Matsushita T, Hamaguchi Y, Horie S, Yahata T, Inoue K, Someya F, Fujimoto M, Takehara K
    • Journal Title

      Rheumatology (Oxford)

      Volume: 50(6) Issue: 6 Pages: 1091-8

    • DOI

      10.1093/rheumatology/keq430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Serum chemokine and cytokine levels as indicators of disease activity in patients with systemic sclerosis.2011

    • Author(s)
      Hasegawa M, et al.
    • Journal Title

      Clin Rheumatol

      Volume: 30 Pages: 231-237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Journal Article] Dermoscopy findings of nail fold capillaries in connective tissue diseases2011

    • Author(s)
      Hasegawa M, et al.
    • Journal Title

      J Dermatol

      Volume: 38 Pages: 66-70

    • NAID

      10027902799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Journal Article] Clinical correlations with dermatomyositis-specific autoantibodies in adult Japanese patients with dermatomyositis: a multicenter cross-sectional study.2011

    • Author(s)
      Hamaguchi Y, Kuwana M, Hoshino K, Hasegawa M, Kaji K, Matsushita T, Komura K, Nakamura M, Kodera M, Suga N, Higashi A, Ogusu K, Muro Y, et al. (全37名中17番目)
    • Journal Title

      Arch. Dermatol.

      Volume: 147 Issue: 4 Pages: 391-398

    • DOI

      10.1001/archdermatol.2011.52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591618, KAKENHI-PROJECT-23591640
  • [Journal Article] Inducible costimulator (ICOS) and ICOS ligand signaling has pivotal roles in skin wound healing via cytokine production2011

    • Author(s)
      Maeda S, Fujimoto M, Matsushita T, Hamaguchi Y, Takehara K, Hasegawa M
    • Journal Title

      Am J Pathol

      Volume: 179(5) Issue: 5 Pages: 2360-9

    • DOI

      10.1016/j.ajpath.2011.07.048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591640
  • [Journal Article] Inducible costimulator ligand(ICOSL) regulates bleomycin-induced Lung and skin fibrosis independently of the ICOS-ICOSL pathway2010

    • Author(s)
      Tanaka C, Fujimoto M, Hamaguchi Y, Sato S, Takehara K, Hasegawa M
    • Journal Title

      Arthritis Rheum

      Volume: 62 Issue: 6 Pages: 1723-32

    • DOI

      10.1002/art.27428

    • NAID

      10029469768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Journal Article] B lymphocytes : shedding new light on the pathogenesis of systemic sclerosis2010

    • Author(s)
      Hasegawa M.
    • Journal Title

      J Dermatol 37

      Pages: 3-10

    • NAID

      10027064811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Journal Article] Reduced red blood cell velocity in nail-fold capillaries as a sensitive and specific indicator of microcirculation injury in systemic sclerosis2009

    • Author(s)
      Mugii N, Hasegawa M, et al.
    • Journal Title

      Rheumatology (Oxford) 48

      Pages: 696-703

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Journal Article] Elevated serum BAFF levels in patients with localized scleroderma in contrast to other organ-specific autoimmune diseases2006

    • Author(s)
      Matsushita T, Hasegawa M, et. al.
    • Journal Title

      Exp Dermatol 16

      Pages: 87-93

    • NAID

      120005756481

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591238
  • [Journal Article] B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis2006

    • Author(s)
      Hasegawa M, et. al.
    • Journal Title

      The American Journal of Pathology 169

      Pages: 954-966

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591238
  • [Journal Article] Elevated serum BAFF levels in patients with localized scleroderma in contrast to other organ-specific autoimmune diseases2006

    • Author(s)
      Matsushita, T., Hasegawa, M., et. al.
    • Journal Title

      Exp Dermatol 16

      Pages: 87-93

    • NAID

      120005756481

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591238
  • [Journal Article] The efficacy of self-administered stretching for finger joint motion in Japanese patients with systemic sclerosis.2006

    • Author(s)
      Mugii N, Hasegawa M, et al.
    • Journal Title

      J Rheumatol 33・8

      Pages: 1586-1592

    • Data Source
      KAKENHI-PROJECT-18591238
  • [Journal Article] B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis2006

    • Author(s)
      Minoru Hasegawa, Yasuhito Hamaguchi, Koichi Yanaba, Jean-David Bouaziz, Junji Uchida, Manabu Fujimoto, Takashi Matsushita, Yukiyo Matsushita, Mayuka Horikawa, Kazuhiro Komura, Kazuhiko Takehara, Shinichi Sato, Thomas F. Tedder
    • Journal Title

      Am J Pathol 169

      Pages: 954-966

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591238
  • [Journal Article] Elevated serum BAFF levels in patients with localized scleroderma in contrast to other organ-specific autoimmune diseases.2006

    • Author(s)
      Matsushita T, Hasegawa M, et al.
    • Journal Title

      Exp Dermatol 16・2

      Pages: 87-93

    • NAID

      120005756481

    • Data Source
      KAKENHI-PROJECT-18591238
  • [Journal Article] The efficacy of self-administered stretching for finger joint motion in Japanese patients with systemic sclerosis2006

    • Author(s)
      Mugii N, Hasegawa M, et. al.
    • Journal Title

      J Rheumatol 33

      Pages: 1586-1592

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591238
  • [Presentation] A curcumin-derivative LG283 that inhibits TGF-β/Smad/Snail-dependent mesenchymal transition ameliorates bleomycin-induced skin fibrosis and vascular injury2021

    • Author(s)
      A. Utsunomiya, T. Chino, N. Oyama, S. Niwa, M. Hasegawa
    • Organizer
      2021 SID Virtual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08769
  • [Presentation] Blockade of CX3CL1-CX3CR1 pathway attenuates skin inflammation, fibrosis, and vascular injury in experimental mouse models of systemic sclerosis2018

    • Author(s)
      Vu Huy Luong, Takenao Chino, Noritaka Oyama, Takashi Matsushita, Takashi Obara, Yoshikazu Kuboi, Naoto Ishii, Akihito Machinaga, Hideaki Ogasawara, Wataru Ikeda, Toshio Imai, Minoru Hasegawa
    • Organizer
      International Investigative Dermatology 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09763
  • [Presentation] Anti-CX3CL1 antibody therapy attenuates the development of inflammation, fibrosis, and vascular injury2017

    • Author(s)
      Vu H. Luong, Takenao Chino, Noritaka Oyama, Takashi Obara, Yoshikazu Kuboi, Naoto Ishii, Akihito Machinaga, Hideaki Ogasawara, Wataru Ikeda, Toshio Imai, Minoru Hasegawa
    • Organizer
      日本研究皮膚科学会第42回年次学術大会・総会
    • Data Source
      KAKENHI-PROJECT-15K09763
  • [Presentation] Anti-CX3CL1 antiboby therapy attenuates the development of bleomycin-induced and growth factors-induced skin fibrosis in mice.2016

    • Author(s)
      Vu H.Luong, Chino T, Oyama N, Kuboi Y, Obara T, Machinaga A, Ogasawara H, Ikeda W, Imai T, Hasegawa M.
    • Organizer
      第45回日本免疫学会総会・学術集会
    • Place of Presentation
      沖縄コンベンションセンター、ラグナガーデンホテル(沖縄県那覇市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-15K09763
  • [Presentation] Anti-CX3CL1 monoclonal antiboby: a promising therapy for systemic sclerosis.2015

    • Author(s)
      Vu H.Luong, Chino T, Tokuriki A, Oyama N, Hasegawa M, Kuboi Y, Obara T, Yasuda N, Muramoto K, Imai T.
    • Organizer
      日本研究皮膚科学会第40回年次学術大会・総会
    • Place of Presentation
      岡山市
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-15K09763
  • [Presentation] Augmented ICOS-ICOS ligand signaling axis in patients with early diffuse cutaneous systemic sclerosis2011

    • Author(s)
      Hasegawa M, Matsushita T, Hamaguchi Y, Fujimoto M, Takehara K
    • Organizer
      ACR/ARHP Scientific Meeting
    • Place of Presentation
      マコーミックプレイス(シカゴ、USA)
    • Year and Date
      2011-11-08
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Presentation] Augmented ICOS-ICOS ligand signaling axis in patients with early diffuse cutaneous systemic sclerosis2011

    • Author(s)
      Minoru Hasegawa
    • Organizer
      ACR/AEHP Scientific Meeting
    • Place of Presentation
      マコーミックプレイス(シカゴ、USA)
    • Year and Date
      2011-11-08
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Presentation] A novel inhibitor of TGF-β/Smad signaling attenuates tissue fibrosis in mouse models of systemic sclerosis2010

    • Author(s)
      Hasegawa M, et al.
    • Organizer
      1'st Systemic Sclerosis World Congress
    • Place of Presentation
      フィレンツェ (イタリア)
    • Year and Date
      2010-02-12
    • Data Source
      KAKENHI-PROJECT-21591456
  • [Presentation] B lymphocyte depletion reduces skin fibrosis and autoimmunity in tight-skin mice2007

    • Author(s)
      Hasegawa M
    • Organizer
      Professor E. Carwaile LeRoy Memorial International Workshop on Scleroderma
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591238
  • [Presentation] B lymphocyte depletion reduces skin fibrosis and autoimmunity in tight-skin mice2007

    • Author(s)
      Hasegawa, M
    • Organizer
      Professor E. Carwaile LeRoy Memorial International Workshop on Scleroderma
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591238
  • 1.  TAKEHARA KAZUHIKO (50142253)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 2.  SATO Shinichi (20215792)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  MATSUSHITA Takashi (60432126)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 4.  Chino Takenao (20521397)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Tokuriki Atsushi (90397274)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OGAWA Yasushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  藤本 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 8.  室 慶直
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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