NEGISHI Youichi 根岸洋一

… Alternative Names

Researcher Number	50286978
Other IDs
External Links
Affiliation (Current)	2019: 東京薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019: 東京薬科大学, 薬学部, 教授 2007 – 2018: Tokyo University of Pharmacy and Life Science, 薬学部, 准教授 2017: 東京薬科大学, 准教授 2006: Tokyo University of Pharmacology, Assistant Professor, 薬学部, 講師 2004 – 2006: 東京薬科大学, 薬学部, 講師 2003 – 2004: 帝京大学, 薬学部, 助手 1998 – 2000: 帝京大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Medical systems / Medical systems / Medical pharmacy / Basic Section 90130:Medical systems-related / Medium-sized Section 90:Biomedical engineering and related fields Except Principal Investigator Surgical dentistry / Biological pharmacy / Environmental pharmacy / Periodontal dentistry / Obstetrics and gynecology / Environmental pharmacy / Biomedical engineering/Biomaterial science and engineering / Pediatrics
Keywords	Principal Investigator 超音波 / リポソーム / 遺伝子導入 / バブルリポソーム / 超音波照射 / 軟骨細胞分化 / p21 / 軟骨細胞 / 超音波造影 / 血管再生 … More Except Principal Investigator 遺伝子導入 / WNT / FGF / 非ウイルスベクター / 骨芽細胞 / アジュバント / ドラッグデリバリーシステム / VEGF / 重力負荷 / アルカリホスファターゼ / オステオカルシン / cAMP / 仮骨延長法 / Wnt3a / LRP5 / 超音波刺激 / 骨形成 / メカニカルストレス / Distraction osteogenesis / Gene Transfer / Ultrasound / Bone Formation / Non-viral vector / Mechanical loading / 細径顎関節内視鏡 / 滑膜細胞 / 骨関節症(OA) / GDF-5 / 滑液解析 / 歯周病 / NF-κB / DNA decoy / 抗炎症効果 / レポーターアッセイ / LPS / NF-κB DNA decoy / ホタルルシフェラーゼ / 病態制御 / CpG-ODN / 粘膜免疫 / IL-12 / IgA / リポソーム / 粘膜ワクチン / IL-6 / ナノキャリアー / アジュバンド / がん幹細胞 / 血管ニッチ / 子宮癌肉腫 / ナノキャリア / バブルリボソーム / 血管新生 / 超音波 / 癌幹細胞 / CD133 / アンジオポエチン / FU-MMT-1 / 機械的刺激 / 骨粗鬆症治療薬 / MAPキナーゼ / mechanical stress / hypergravity / osteoblasts / bone-forming agents / alkaline phosphatase / MAP kinase / osteocalcin / 擬似微小重力 / ビタミンD_3 / 細胞質骨格系 / サイトカラシンB / 微小重力環境 / クリノスタット培養 / クメステロール類縁体(KCA-098) / 1α、25-(OH)_2D_3 / 低重力環境 / 高重力環境 / OUASI-MICROGRAVITY / OSTEOBLASTS / ALKALINE PHOSPHATASE / OSTEOCALCIN / VITAMIN D3 / CYTOSKELETON / CYTOCHALASINB / 内軟骨性骨化 / 膜性骨化 / 軟骨細胞 / COX-2 / 骨折治癒過程 / 骨細胞 / gene transfer / distraction osteogenesis / fibrous ossification / enchondral ossification / chondrogenesis / cox-2 / 擬似微小重力環境 / 破骨細胞 / RAW276.4細胞 / クリノスタット回転培養 / 副甲状腺ホルモン / 活性型ビタミンD_3 / プロスタグランジン / exposure of hyper-gravity / quasi-microgravity / osteoclast / RAW276.4 cells / clinostat / parathyroid hormone / 1α,25(OH)_2D_3 / prostaglandin / 仮骨延長 / COX2 / 薬物送達システム / モノイオンコンプレックス / プラスミドＤＮＡ / ポリエチレングリコール / スプライシング異常 / 筋ジストロフィー / RNA創薬 / 福山型筋ジストロフィー / 中枢異常 / バイオマーカー / 核酸医薬 / 中枢性疾患モデル / アンチセンス核酸 / 分子標的治療 / ドラッグデリバリー / フクチン Less

光音響と超音波応答性ナノバブルによる革新的セラノスティクスシステムの開発Principal InvestigatorOngoing
- Principal Investigator
  
  根岸洋一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of ultrasound-responsive nanobubbles containing genome editing tools and establishment of disease treatment systemPrincipal InvestigatorOngoing
- Principal Investigator
  
  根岸洋一
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
環状DNA単分子の高密度凝縮化技術による生体個体内未踏空間送達システムの創製Ongoing
- Principal Investigator
  
  朝山章一郎
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Metropolitan University
超音波応答性ナノバブルによる抗体デリバリーシステムの開発と乳がん治療戦略Principal InvestigatorOngoing
- Principal Investigator
  
  根岸洋一
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of ultrasound-responsive nanobubbles containing physiologically active gas and construction of disease treatment systemPrincipal Investigator
- Principal Investigator
  
  Negishi Yoichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
Research on Fukuyama musucular dystrophy towards clincal trial using antisense oligonucleotids
- Principal Investigator
  
  Taniguchi-Ikeda Mariko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
子宮癌肉腫幹細胞の血管ニッチを制御する治療法の開発と癌幹細胞治療への展開Ongoing
- Principal Investigator
  
  江本精
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  International University of Health and Welfare
Ultrasound-mediated gene delivery system into brain tissue by blood brain barrier targeting Bubble liposomesPrincipal Investigator
- Principal Investigator
  
  Yoichi NEGISHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
Therapeutic systems of muscular dystrophy by morpholino oligonucleotide-loaded nanobubble and ultrasoundPrincipal Investigator
- Principal Investigator
  
  NEGISHI yoichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
IL-6 acts as a key cytokine in the augmentation of mucosal immunity following intranasal administration of antigen with liposomes
- Principal Investigator
  
  ARAMAKI Yukihiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Gene transfer system into mesenchymal stem cell by peptide-modified liposomes and ultrasound technologyPrincipal Investigator
- Principal Investigator
  
  NEGISHI Yoichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
Low invasive therapeutic system for vascular diseases by neovascular specific liposomes containing US-contrast gasPrincipal Investigator
- Principal Investigator
  
  NEGISHI Yoichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
Application of CpG-ODN for nasal vaccine development
- Principal Investigator
  
  ARAMAKI Yukihiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
新規な超音波造影ガス封入リポソームによる非侵襲的虚血性血管再生療法のシステム開発Principal Investigator
- Principal Investigator
  
  根岸洋一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
The promotional effect for bone formation by ultrasound mediated gene transfer (sonoporation) on Wnt-related gene at sites of distraction osteogenesis
- Principal Investigator
  
  SETO Kanichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tsurumi University
The promotional effect for bone formation by ultrasound mediated gene transfer (sonoporation) on osteogenetic gene at sites of distraction osteogenesis
- Principal Investigator
  
  SEKIYA Hideki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Toho University
NF-κB DNA decoyを用いた炎症関連遺伝子発現の調節による歯周病態制御
- Principal Investigator
  
  和泉雄一
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Kagoshima University
The effect of gravitational alteration on the formation and activation of osteoclast.
- Principal Investigator
  
  KAWASHIMA Kohtaro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Teikyo University
顎関節腔内滑膜病変に対するGDF-5遺伝子導入による修復効果
- Principal Investigator
  
  SETO Kan-ichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Tsurumi University
関節軟骨疾患をターゲットとした細胞周期調節因子p21遺伝子による軟骨再生の試みPrincipal Investigator
- Principal Investigator
  
  根岸洋一
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
  Teikyo University
Study of osteogenetic effect on the fracture callus of facial bone by LRP5 gene transfer
- Principal Investigator
  
  SETO Kan-ichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tsurumi University
The changes of bone metabolism induced by quasi-microgravity and its recovery by the bone-metabolizing agents.
- Principal Investigator
  
  KAWASHIMA Kohtaro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  TEIKYO UNIVERSITY
CO-OPERATIVE EFFECTS OF HYPERGRAVITY AND BONE FORMING AGENTS ON THE METABOLISM OF OSTEOBLASTS
- Principal Investigator
  
  KAWASHIMA Kohtaro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Teikyo University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 核酸導入キャリアーとしての超音波造影ガス封入バブルリポソームの開発2006
- Author(s)
  根岸洋一
- Total Pages
  86
- Publisher
  薬剤学,66(4),267-271,日本薬剤学会出版部
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592117
[Book] 核酸導入キャリアーとしての超音波造影ガス封入バブルリポソームの開発2006
- Author(s)
  根岸洋一
- Total Pages
  86
- Publisher
  薬剤学,66(4),267-271,日本薬剤学会出版部
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390546
[Book] 核酸導入キャリアーとしての超音波造影ガス封入バブルリポゾームの開発2006
- Author(s)
  根岸洋一
- Total Pages
  86
- Publisher
  薬剤学,66(49), 267-271, 日本薬剤学会出版会
- Data Source
  KAKENHI-PROJECT-17592117
[Journal Article] By-Product-Free Intact Modification of Insulin by Cholesterol End-Modified Poly(ethylene glycol) for In Vivo Protein Delivery2018
- Author(s)
  S. Asayama,* K. Nagashima, Y. Negishi, H. Kawakami
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 29 Pages: 67-73
- DOI
  10.1021/acs.bioconjchem.7b00593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03183, KAKENHI-PROJECT-16K12899
[Journal Article] The Development of an Ultrasound-mediated Nucleic Acid Delivery System for Treating Muscular Dystrophies2018
- Author(s)
  Negishi Y, Hamano N, Shiono H, Akiyama S, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  薬学雑誌
  
  Volume: 132 Issue: 12 Pages: 1383-1388
- DOI
  10.1248/yakushi.12-00235-2
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-09-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-23300193
[Journal Article] Gene delivery systems by the combination of lipid bubbles and ultrasound2016
- Author(s)
  Negishi Y, Endo-Takahashi Y, Maruyama K.
- Journal Title
  
  Drug Discov. Ther.
  
  Volume: 10 Pages: 248-255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462536
[Journal Article] Tumor growth suppression by the combination of nanobubbles and ultrasound2016
- Author(s)
  Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J,Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Pages: 217-113
- DOI
  10.1111/cas.12867
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26560264, KAKENHI-PROJECT-25860397, KAKENHI-PROJECT-16K21383, KAKENHI-PROJECT-26462536
[Journal Article] Enhancement of Blood-Brain Barrier Permeability and Delivery of Antisense Oligonucleotides or Plasmid DNA to the Brain by the Combination of Bubble Liposomes and High-Intensity Focused Ultrasound.2015
- Author(s)
  Negishi Y, Yamane M, Kurihara N, Endo-Takahashi Y, Sashida S, Takagi N, Suzuki R, Maruyama K.
- Journal Title
  
  Pharmaceutics
  
  Volume: 7 Pages: 344-362
- DOI
  10.3390/pharmaceutics7030344
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560240
[Journal Article] Bubble Liposomes and Ultrasound Exposure Improve Localized Morpholino Oligomer Delivery into Skeletal Muscles of Dystrophic mdx Mice2014
- Author(s)
  Negishi Y, Ishii Y, Shiono H, Akiyama S, Sekine S, Kojima T, Mayama S, Kikuchi T, Hamano N, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 11 Pages: 1053-1061
- DOI
  10.1021/mp4004755
- Data Source
  KAKENHI-PROJECT-23300193
[Journal Article] Delivery of an angiogenic gene into ischemic muscle by novel bubble liposomes followed by ultrasound exposure.2011
- Author(s)
  Y.Negishi, K.Matsuo, Y.Endo-Takahashi, K.Suzuki, Y.Matsuki, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
- Journal Title
  
  Pharm.Res.
  
  Volume: 28 Pages: 712-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Delivery of an Angiogenic Gene into Ischemic Muscle by Novel Bubble Liposomes Followed by Ultrasound Exposure.2011
- Author(s)
  Negishi Y, Matsuo K, Endo-Takahashi Y, Suzuki K, Matsuki Y, Takagi N, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  Pharm.Res. 28
  
  Pages: 712-719
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Enhanced laminin-derived peptide AG73-mediated liposomal gene transfer by bubble liposomes and ultrasound.2010
- Author(s)
  Y.Negishi, D.Omata, H.lijima, Y.Takabayashi, K.Suzuki, Y.Endo, R.Suzuki, Maruyama, M.Nomizu, Y.Aramaki
- Journal Title
  
  Mol.Pharm. 7
  
  Pages: 217-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Preparation and characterization of laminin-derived peptide AG73-coated liposomes as a selective gene delivery tool.2010
- Author(s)
  Y.Negishi, D.Omata, H.Iijima, N.Hamano, Y Endo-Takahashi, M Nomizu, Y
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 33 Pages: 1766-1769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2010
- Author(s)
  Y.Negishi, S.Sekine, Y.Endo, N.Nishijima, R.Suzuki, K.Maruyama, Y.Aramaki
- Journal Title
  
  9^<th> International Symposium Therapeutic Ultrasound. AIP conference proceedings 1215
  
  Pages: 299-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Development of gene delivery system into skeletal muscles by bubble liposomes and ultrasound.2010
- Author(s)
  Negishi Y, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  YAKUGAKU ZASSHI 130
  
  Pages: 1489-1496
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Preparation and characterization of laminin-derived peptide AG73-coated liposomes as a selective gene delivery tool.2010
- Author(s)
  Negishi Y, Omata D, Iijima H, Hamano N, Endo-Takahashi Y, Nomizu M, Aramaki Y
- Journal Title
  
  Biol Pharm Bull. 33
  
  Pages: 1766-1769
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Enhanced laminin-derived peptide AG73-mediated liposomal gene transfer by bubble liposomes and ultrasound.2010
- Author(s)
  Negishi Y, Omata D, Iijima H, Takabayashi Y, Suzuki K, Endo Y, Suzuki R, Maruyama K, Nomizu M, Aramaki Y
- Journal Title
  
  Mol Pharm. 7
  
  Pages: 217-226
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Development of gene delivery system into skeletal muscles by bubble liposomes and ultrasound.2010
- Author(s)
  Y.Negishi, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, Y.Aramaki
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 130 Pages: 1489-1496
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2009
- Author(s)
  Negishi Y, Sekine S, Endo Y, Nishijima N, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  9th International Symposium Therapeutic Ultrasound. AIP Conf.Proc. 1215
  
  Pages: 299-302
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Ultrasound Imaging and Gene Delivery by AG73-modified Bubble Liposomes2009
- Author(s)
  Y. Negishi, Y. Tsunoda, N. Hamano, Y. Endo, N. Takagi, R. Suzuki, K, Maruyama, C. Batsuren, M. Emoto, M. Nomizu, Y. Aramaki
- Journal Title
  
  Peptide Science 2008
  
  Pages: 127-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Ultrasound imaging and gene delivery by AG73-modified bubble liposomes2009
- Author(s)
  Negishi Y, Tsunoda Y, Endo Y, Takagi N, Suzuki R, Maruyama K, Emoto M, Nomizu M, Aramaki A
- Journal Title
  
  Peptide Science 2008
  
  Pages: 127-130
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] AG73-mediated Liposomal Gene Transfection Accelerated by Bubble Liposomes and Ultrasound2009
- Author(s)
  D. Omata, Y. Negishi, Y. Endo, R. Suzuki, K. Suzuki, K. Maruyama, M. Nomizu, Y. Aramaki
- Journal Title
  
  Peptide Science 2008
  
  Pages: 73-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] 超音波を利用した動物細胞への核酸導入技術の開発2007
- Author(s)
  根岸洋一
- Journal Title
  
  BRAIN TECHNO NEWS 124
  
  Pages: 22-26
- Data Source
  KAKENHI-PROJECT-18650146
[Journal Article] Bubble libosome2006
- Author(s)
  Negishi Y
- Journal Title
  
  Yakuzaigaku 66(4)
  
  Pages: 267-271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390546
[Journal Article] Bubble libosome2006
- Author(s)
  Yohichi Negishi
- Journal Title
  
  Yakuzaigaku 66 (4)
  
  Pages: 267-271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592117
[Journal Article] Injectable Growth/Differentiation Factor-5/ Recombinant Human Collagen Composite induces endochondral ossification via Sox9 Expression and angiogenesis in murine calvariae
- Author(s)
  Kadomatsu H, Matsuyama T, Yoshimoto T, Negishi Y, Sekiya H, Yamamoto M, Izumi Y
- Journal Title
  
  Journal of Periodontal Research (In Press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592117
[Journal Article] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis
- Author(s)
  Negishi Y, Endo-Takahashi Y, Takagi N, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  10th International Symposium Therapeutic Ultrasound. AIP Conf.Proc. (in press)
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Injectable Growth/Differentiation Factor-5/ Recombinant Human Collagen Composite induces endochondral ossification via Sox9 Expression and angiogenesis in murine calvariae
- Author(s)
  Kadomatsu H, Matsuyama T, Yoshimoto T, Negishi Y, Sekiya H, Yamamoto M, Izumi Y
- Journal Title
  
  Journal of Periodontal Research (In Press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390546
[Presentation] 一酸化窒素ガスを内封した超音波応答性バブルリポソームの開発2018
- Author(s)
  根岸洋一、澤田ほのか、韮沢慧、異島優、髙橋葉子、笹山瑞紀、鈴木亮、丸山一雄、丸山徹
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H03037
[Presentation] インスリン/コレステロール末端修飾PEG複合体による血糖降下作用2018
- Author(s)
  朝山章一郎，長嶋果南，根岸洋一，川上浩良
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] インスリンの非共有結合PEGylation:コレステロール末端修飾PEGとインスリンの複合体形成2017
- Author(s)
  朝山章一郎，長嶋果南，根岸洋一，川上浩良
- Organizer
  第33回日本DDS学術集会
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] コレステロール末端修飾PEGによるインスリンの非共有結合PEGylation2017
- Author(s)
  朝山章一郎，長嶋果南，根岸洋一，川上浩良
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] Biocompatible Highly Condensed Plasmid DNA for In Vivo Diffusive Delivery2017
- Author(s)
  Shoichiro Asayama, Atsushi Nohara, Sakura Taneichi, Yoichi Negishi, Hiroyoshi Kawakami
- Organizer
  The 25th Anniversary Congress of the European Society of Gene & Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] Development of nitric oxide gas encapsulating liposomes2017
- Author(s)
  Y. Negishi, H. Sawada, Y. Ishima, R. Suzuki, K. Maruyama, T, Maruyama, and Y. Endo-Takahashi
- Organizer
  The 16th International Symposium on Advanced Technology (ISAT-16)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03037
[Presentation] pDNA/PEGモノイオンコンプレックスの機能向上とオリゴイオンコンプレックスの形成2017
- Author(s)
  朝山章一郎，種市さくら，根岸洋一，川上浩良
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] 一酸化窒素ガス内封ナノ・マイクロバブルの調製と物性評価2017
- Author(s)
  澤田ほのか、韮沢慧、異島優、髙橋葉子、鈴木亮、丸山一雄、新槇幸彦、丸山徹、根岸洋一
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03037
[Presentation] Design of Mono-Ion Complex for In Vivo Diffusive Plasmid DNA Delivery2017
- Author(s)
  Shoichiro Asayama, Atsushi Nohara, Sakura Taneichi, Yoichi Negishi, Hiroyoshi Kawakami
- Organizer
  44th Annual Meeting & Exposition of the Controlled Release Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] 持続的遺伝子発現型pDNA/PEGモノイオンコンプレックスの分子設計2017
- Author(s)
  朝山章一郎，種市さくら，根岸洋一，川上浩良
- Organizer
  遺伝子・デリバリー研究会第17回シンポジウム
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] Mono-Ion Complex for In Vivo Plasmid DNA Delivery2016
- Author(s)
  S. Asayama, A. Nohara, Y. Negishi, H. Kawakami
- Organizer
  3rd International Conference on Biomaterials Science in Tokyo (ICBS2016)
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] PEGジレンマ解消型pDNA/PEGモノイオンコンプレックスの分子設計2016
- Author(s)
  種市さくら、朝山章一郎、根岸洋一、川上浩良
- Organizer
  第45回医用高分子シンポジウム
- Place of Presentation
  産業技術総合研究所（東京都江東区）
- Year and Date
  2016-07-25
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] 超泳動pDNA/PEGモノイオンコンプレックスへの生分解性エステル基導入効果2016
- Author(s)
  種市さくら、朝山章一郎、根岸洋一、川上浩良
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] PEGジレンマ解消型pDNA/PEGモノイオンコンプレックスの持続的in vivo遺伝子発現評価2016
- Author(s)
  朝山章一郎、種市さくら、根岸洋一、川上浩良
- Organizer
  日本バイオマテリアル学会シンポジウム2016
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-11-21
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] セラノスティックスを可能とする超音波応答性ナノバブルによる核酸・遺伝子デリバリー2016
- Author(s)
  根岸洋一、髙橋葉子、鈴木　亮、丸山一雄、新槇幸彦
- Organizer
  日本薬学会　第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] 超泳動pDNA/PEGモノイオンコンプレックスのPEGジレンマ解消2016
- Author(s)
  種市さくら、朝山章一郎、根岸洋一、川上浩良
- Organizer
  遺伝子・デリバリー研究会第16回シンポジウム
- Place of Presentation
  川崎生命科学・環境研究センター (神奈川県川崎市）
- Year and Date
  2016-05-16
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] Plasmid DNA Mono-Ion Complexes with Poly(ethylene glycol) for In Vivo Diffusive Gene Delivery2016
- Author(s)
  S. Asayama, A. Nohara, Y. Negishi, H. Kawakami
- Organizer
  10th World Biomaterials Congress
- Place of Presentation
  Montreal (Canada)
- Year and Date
  2016-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] PEGジレンマ解消型超泳動pDNA/PEGモノイオンコンプレックスの生体組織内拡散性2016
- Author(s)
  種市さくら、朝山章一郎、根岸洋一、川上浩良
- Organizer
  第65回高分子討論会
- Place of Presentation
  神奈川大学（神奈川県横浜市）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-16H03183
[Presentation] pDNA搭載型アニオン性脂質含有バブルリポソームによる脳内遺伝子デリバリー2015
- Author(s)
  山垣内貴文、根岸洋一、栗原奈保、髙橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  第59回　日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県船橋市）
- Year and Date
  2015-09-02
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] アニオン性脂質含有バブルリポソームと高密度集束超音波による血液脳関門透過性亢進と脳内遺伝子デリバリー2015
- Author(s)
  栗原奈保、根岸洋一、山根正也、山垣内貴文、髙橋葉子、高木教夫、鈴木　亮、丸山一雄、新槇幸彦
- Organizer
  日本薬剤学会　第30年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] バブルリポソームと集束超音波による脳内遺伝子デリバリー2015
- Author(s)
  根岸洋一、栗原奈保、山垣内貴文、髙橋葉子、鈴木　亮、丸山一雄、新槇幸彦
- Organizer
  第31回　日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] バブルリポソームと高密度集束超音波併用による脳内へのアンチセンス核酸・遺伝子デリバリー2015
- Author(s)
  根岸洋一、栗原奈保、髙橋葉子、指田紗菜恵、高木教夫、鈴木　亮、丸山一雄、新槇幸彦
- Organizer
  日本核酸医薬学会　第1回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] ナノバブルと高密度集束超音波併用による血液脳関門透過性亢進と脳内遺伝子デリバリー2015
- Author(s)
  根岸洋一、髙橋葉子、栗原奈保、鈴木亮、丸山一雄、高木教夫、新槇幸彦
- Organizer
  第14回日本超音波治療研究会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県高知市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] pDNA搭載型アニオン性脂質含有バブルリポソームによる遺伝子デリバリー2015
- Author(s)
  山垣内貴文、根岸洋一、栗原奈保、髙橋葉子、鈴木　亮、丸山一雄、新槇幸彦
- Organizer
  遺伝子・デリバリー研究会　第15回シンポジウム
- Place of Presentation
  京都薬科大学（京都府山科区）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] ナノバブルと集束超音波併用による脳内分子デリバリーシステムの構築2015
- Author(s)
  根岸洋一、栗原奈保、髙橋葉子、鈴木　亮、丸山一雄、高木教夫、新槇幸彦
- Organizer
  遺伝子・デリバリー研究会　第15回シンポジウム
- Place of Presentation
  京都薬科大学（京都府山科区）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] バブルリポソームと超音波照射併用による臓器選択的核酸デリバリーシステムの開発2015
- Author(s)
  根岸洋一、櫻井あかね、高橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  平成26年度　第4回超音波分子診断治療研究会
- Place of Presentation
  福岡大学医学部
- Year and Date
  2015-03-07
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] バブルリポソームと超音波照射併用した修飾型モルフォリノオリゴ導入による筋ジストロフィー治療システムの開発2014
- Author(s)
  間山彩, 根岸洋一, 秋山早希, 櫻井あかね, 高橋葉子, 片桐文彦, 野水基義, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと高密度集束超音波併用による血液脳関門透過性亢進に関する基礎的検討2014
- Author(s)
  山根正也,　根岸洋一,　栗原奈保,　髙橋葉子,　鈴木亮, 丸山一雄, 高木教夫,　新槇幸彦
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] バブルリポソームと高密度焦点式超音波による核酸導入法の確立2013
- Author(s)
  山根正也, 根岸洋一, 奥津大輔, 濱野展人, 小俣大樹, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第13回遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] Intravenous antisense oligonucleotides delivery system with Bubble liposomes and ultrasound exposure into skeletalmuscles of the mdx mice2013
- Author(s)
  Negishi Y, Akiyama S, Mayama S, Yamane M, End-Takahashi Y, Suzuki R, Maruyama K, and Arammaki Y
- Organizer
  5th Asian Arden Conference
- Place of Presentation
  Nagoya
- Year and Date
  2013-08-05
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 筋ジストロフィー疾患治療のための超音波併用バブルリポソームによるアンチセンスデリバリーシステムの構築2013
- Author(s)
  間山彩, 根岸洋一, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第13回遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと高密度焦点式超音波(HIFU)による骨格筋への局限的遺伝子デリバリー2013
- Author(s)
  奥津　大輔、根岸　洋一、濱野　展人、小俣　大樹、髙橋　葉子、鈴木　亮、丸山　一雄、新槇　幸彦
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] アニオン性脂質含有バブルリポソームの開発2013
- Author(s)
  根岸洋一, 菊池太希, 高橋葉子, 小栗由貴子, 杉本勝俊, 森安史典, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第12回日本超音波治療研究会
- Place of Presentation
  東京
- Year and Date
  2013-11-30
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと超音波を利用した心臓への核酸デリバリーシステムの有用性評価2013
- Author(s)
  根岸洋一, 秋山早希, 山根正也, 間山彩, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 筋ジストロフィーモデルマウス心筋へのバブルリポソーム併用超音波核酸デリバリーと組織内分布2013
- Author(s)
  秋山早希, 根岸洋一, 間山彩, 山根正也, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと超音波照射併用による心臓への核酸デリバリー2012
- Author(s)
  根岸洋一, 塩野瞳, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第12回遺伝子・デリバリー研究会夏季セミナー
- Place of Presentation
  北九州
- Year and Date
  2012-07-30
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 超音波応答性バブルリポソームの核酸・遺伝子デリバリーシステムへの応用展開2012
- Author(s)
  根岸洋一、高橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2011
- Place of Presentation
  大阪大学コンベンションセンター、大阪(招待講演)
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 核移行シグナルペプチド内封AG73修飾リポソームによる新規遺伝子デリバリーツールの開発2012
- Author(s)
  根井彰浩,根岸洋一,高橋佐慧子,小俣大樹,鈴木亮,丸山一雄,野水基義,新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] 筋ジストロフィー治療に向けた超音波核酸デリバリーシステムの開発2012
- Author(s)
  濱野展人、根岸洋一、塩野瞳、秋山早希、高橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 筋ジストロフィー治療に向けた超音波核酸デリバリーシステムの開発2012
- Author(s)
  濱野展人, 根岸洋一, 塩野瞳, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第132年会
- Place of Presentation
  大阪
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 核移行シグナルペプチド内封AG73修飾リポソームによる新規遺伝子デリバリーツールの開発2012
- Author(s)
  根井　彰浩、根岸　洋一、高橋　佐慧子、小俣　大樹、鈴木　亮、丸山　一雄、野水　基義、新槇　幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] バブルリポソームと超音波照射併用による心筋への核酸デリバリー2012
- Author(s)
  根岸洋一, 塩野瞳, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Place of Presentation
  仙台
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと超音波照射併用による心臓への核酸デリバリー2012
- Author(s)
  根岸洋一,　塩野瞳,　秋山早希, 髙橋葉子,　鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第12回遺伝子・デリバリー研究会　夏季セミナー
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] DOTAP含有バブルリポソームによる全身循環を介した下肢虚血部位への超音波遺伝子導入法の検討2011
- Author(s)
  松木勇樹, 根岸洋一, 高橋葉子, 加藤妥治, 高山華奈, 高木教夫, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] バブルリポソーム併用超音波遺伝子デリバリーシステムの疾患治療への応用2011
- Author(s)
  根岸洋一,高橋葉子,高木教夫,鈴木亮,丸山一雄,新槇幸彦
- Organizer
  第3回超音波とマイクロバブルの相互作用に関するシンポジウム
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] PMO delivery system with Bubble liposomes and ultrasound exposure into skeletal muscles of the mdx mice2011
- Author(s)
  Y.Negishi, Y.Ishii, S.Sekine, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  American Society of Gene & Cell Therapy 14th Annual Meeting
- Place of Presentation
  Washington State Convention & Trade Center, Seattle, USA
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] PMO delivery system with Bubble liposomes and ultrasound exposure into skeletal muscles of the mdx mice2011
- Author(s)
  Negishi Y, Ishii Y, Sekine S, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
- Organizer
  American Society of Gene & Cell Therapy 14th Annual Meeting
- Place of Presentation
  Seattle
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソーム併用超音波遺伝子導入法を用いた間葉系幹細胞への遺伝子導入効果の解析2011
- Author(s)
  鈴木健太郎, 根岸洋一, 高橋葉子, 高橋良太, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第131 年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] バブルリポソーム併用超音波遺伝子導入法を用いた間葉系幹細胞への遺伝子導入効果の解析2011
- Author(s)
  鈴木健太郎, 根岸洋一, 高橋葉子, 高橋良太, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] バブルリポソーム併用超音波遺伝子デリバリーシステムの疾患治療への応用2011
- Author(s)
  根岸洋一, 高橋葉子, 高木教夫, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第3回超音波とマイクロバブルの相互作用に関するシンポジウム
- Place of Presentation
  横浜
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 超音波応答性バブルリポソームの核酸・遺伝子デリバリーシステムへの応用展開2011
- Author(s)
  根岸洋一, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2011
- Place of Presentation
  大阪
- Year and Date
  2011-09-02
- Invited
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] bFGF Gene Transfer into Skeletal Muscle of Hindlimb Ischemia Model by Bubble Liposome and Ultrasound2010
- Author(s)
  Y.Negishi, Y.Endo-Takahashi, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  International Liposome Research Days and Lipids, Liposomes, & Membrane Biophysics
- Place of Presentation
  University of British Columbia (Vancouver)
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Development of AG73-modified Bubble liposomes as a vascular targeting ultrasound contrast agents2010
- Author(s)
  Y. Negishi, N. Hamano, Y. Endo-Takahashi, R. Suzuki, K. Maruyama, M. Nomizu, M. Emoto, Y. Aramaki
- Organizer
  The 2010 World Molecular Imaging Congress
- Place of Presentation
  Kyoto
- Year and Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Ultrasound-targeted Bubble Liposomes Destruction Enhances AG73-mediated Gene Transfer by Improvement of Intracellular Trafficking2010
- Author(s)
  D.Omata, Y.Negishi, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, M.Nomizu, Y.Aramaki
- Organizer
  10^<th> International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Ultrasound imaging of tumor model by AG73 peptide modified Bubble liposomes2010
- Author(s)
  N. Hamano, Y. Negishi, Y. Endo-Takahashi, R. Suzuki, K. Maruyama, M. Nomizu, C. Batsuren, M. Emoto, Y. Aramaki
- Organizer
  12th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  Tokyo
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] In vivo gene delivery system by Bubble liposomes and Ultrasound2010
- Author(s)
  Y.Negishi, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  12th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  Tokyo
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] bFGF Gene Transfer into Skeletal Muscle of Hindlimb Ischemia Model by Bubble Liposome and Ultrasound, International Liposome Research Days and Lipids2010
- Author(s)
  Y. Negishi, Y. Endo-Takahashi, N. Takagi, R.Suzuki, K. Maruyama, Y. Aramaki,
- Organizer
  Liposomes, & Membrane Biophysics
- Place of Presentation
  Vancouver
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] In vivo gene delivery system by Bubble liposomes and Ultrasound2010
- Author(s)
  Y. Negishi, Y. Endo-Takahashi, R. Suzuki, K. Maruyama, Y. Aramaki
- Organizer
  12th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  Tokyo(招待講演)
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Enhanced Gene Delivery of AG73-modified Liposomes with Bubble Liposomes and Ultrasound Exposure by Improving Intracellular Trafficking2010
- Author(s)
  D.Omata, Y.Negishi, K.Suzuki, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, M.Nomizu, Y.Aramaki
- Organizer
  International Liposome Research Days and Lipids, Liposomes, & Membrane Biophysics
- Place of Presentation
  University of British Columbia (Vancouver)
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis2010
- Author(s)
  Y.Negishi, K.Matsuo, Y.Endo-Takahashi, K.Suzuki, Y.Matsuki, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  10^<th> International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] AG73ペプチド修飾バブルリポソームを用いた新生血管を標的化する新規超音波造影剤の開発2010
- Author(s)
  濱野展人,根岸洋一,遠藤葉子,鈴木亮,丸山一雄,野水基義,Choijamts Batsuren,江本精,新槇幸彦
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Ultrasound-targeted Bubble Liposomes Destruction Enhances AG73-mediated Gene Transfer by Improvement of Intracellular Trafficking2010
- Author(s)
  D. Omata, Y.Negishi, Y. Endo-Takahashi, R. Suzuki, K.Maruyama, M. Nomizu, Y.Aramaki
- Organizer
  10th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] バブルリポソームと超音波技術の融合による下肢虚血モデルへのbFGF/SDF-1遺伝子導入効果の解析2010
- Author(s)
  根岸洋一,鈴木健太郎,遠藤葉子,高木教夫,鈴木亮,丸山一雄,新槇幸彦
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 新生血管を標的化するAG73ペプチド修飾バブルリポソームの作製と超音波造影効果の解析2010
- Author(s)
  濱野展人, 根岸洋一, 高橋葉子, 鈴木亮, 丸山一雄, 野水基義, Choijamts Batsuren, 江本精, 新槇幸彦
- Organizer
  遺伝子・デリバリー研究会第10回夏期セミナー
- Place of Presentation
  滋賀
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis2010
- Author(s)
  Y.Negishi, K. Matsuo, Y. Endo-Takahashi, K. Suzuki, Y. Matsuki, N. Takagi, R. Suzuki, K.Maruyama, Y.Aramaki,
- Organizer
  10th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] バブルリポソームと超音波技術を融合した筋組織への遺伝子導入システムの開発2010
- Author(s)
  根岸洋一
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山(招待講演)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2009
- Author(s)
  Y.Negishi, S.Sekine, Y.Endo, N.Nishijima, R.Suzuki, K.Maruyama, Y, Aramaki
- Organizer
  9th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  France
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 超音波技術を利用した下肢虚血モデルへのbFGF/SDF-1遺伝子導入効果の解析2009
- Author(s)
  根岸洋一,松尾慶子,遠藤葉子,鈴木健太郎,高木教夫,鈴木亮,丸山一雄,新槇幸彦
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 超音波エネルギーを利用した筋組織への経静脈的核酸導入法の検討2009
- Author(s)
  関根祥子、根岸洋一、西島信明、石井優子、遠藤葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  日本超音波医学会第82回学術集会
- Place of Presentation
  東京
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2009
- Author(s)
  Y. Negishi, S. Sekine, Y. Endo, N. Nishijima, R. Suzuki, K. Maruyama, Y. Aramaki
- Organizer
  9th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Aix en Provence
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Gene Transfer of bFGF into Skeletal Muscle of Murine Hindlimb Ischemia Model by Echo-contrast Gas Entrapping Liposomes2008
- Author(s)
  K. Matsuo, Y. Negishi, Y. Endo-Takahashi, N. Takagi, R. Suzuki, K. Maruyama, Y.Aramaki
- Organizer
  Bubble liposomes and Ultrasound 11th Liposome Research Days Conference
- Place of Presentation
  横浜
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] リポソームを用いたCpG-ODNの経鼻投与による粘膜免疫の賦活化2008
- Author(s)
  本庄絵美, 根岸洋一, 國澤純, 清野宏, 新槇幸彦
- Organizer
  第38 回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] Ultrasound imaging and gene delivery by AG73-modified bubble liposomes2008
- Author(s)
  Yoichi Negishi
- Organizer
  45th Japanease Peptide Symposium
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Development of AG73-modified Bubble liposomes as a targeted ultrasound imaging gas2008
- Author(s)
  根岸洋一
- Organizer
  The 10th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  東京
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Liposome を用いたCpG-ODN 経鼻投与による粘膜免疫の賦活化2007
- Author(s)
  高山典子, 本庄絵美, 根岸洋一, 國澤純, 清野宏, 新槇幸彦
- Organizer
  日本薬剤学会第22年会
- Place of Presentation
  大宮
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] Local delivery of plasmid DNA into skeletal muscles by echo-contrast gas entrapping liposomes, "Bubble liposomes"2007
- Author(s)
  根岸洋一
- Organizer
  American Society of Gene Therapy 10th Annual Meeting
- Place of Presentation
  Seattle, USA
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18650146
[Presentation] バブルリポソームによる超音波遺伝子送達システムのin vivo局所への適用2007
- Author(s)
  根岸洋一
- Organizer
  第23回日本DDS学会
- Place of Presentation
  熊本
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-18650146
[Presentation] Enhanced gene transfer into skeletal muscle by echo-contrast gas entrapping liposomes, "Bubble liposomes"2007
- Author(s)
  根岸洋一
- Organizer
  The 9th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  Osaka, JAPAN
- Year and Date
  2007-12-16
- Data Source
  KAKENHI-PROJECT-18650146
[Presentation] SPG-R8 を用いたCpG-ODN の経鼻投与による粘膜免疫の賦活化2007
- Author(s)
  高山典子, 根岸洋一, 國澤純, 清野宏, 櫻井和朗, 新槇幸彦
- Organizer
  第23 回日本DDS 学会
- Place of Presentation
  熊本
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] SPG-R8を用いたCpG-ODN の経鼻投与による粘膜アジュバント効果の増強. 遺伝子デリバリー研究会2007
- Author(s)
  高山典子, 河野麻子, 根岸洋一, 國澤純, 清野宏, 櫻井和朗, 新槇幸彦
- Organizer
  第7 回シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] バブルリポソームと集束超音波を併用した核酸導入法の基礎的検討
- Author(s)
  根岸洋一、山村翔、奥津大輔、高橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  第4回超音波分子診断治療研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] Enhancement of Blood-Brain Barrier Permeability by the Combination of Bubble Liposomes and High-intensity focused ultrasound
- Author(s)
  Yoichi Negishi, Masaya Yamane, Naho Kurihara, Endo-Takahashi Yoko, Norio Takagi, Ryo Suzuki, Kazuo Maruyama, Yukihiko Aramaki
- Organizer
  Focused Ultrasound 2014 - 4th International Symposium
- Place of Presentation
  Bethesda, USA
- Year and Date
  2014-10-12 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] 筋ジストロフィー疾患治療のための超音波併用バブルリポソームによるアンチセンスデリバリーシステムの構築
- Author(s)
  間山　彩、根岸　洋一、秋山　早希、髙橋　葉子、鈴木　亮、丸山　一雄、新槇　幸彦
- Organizer
  第13回遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと高密度焦点式超音波併用による血液脳関門透過性亢進に関する基礎的検討
- Author(s)
  山根　正也、根岸　洋一、栗原　奈保、髙橋　葉子、鈴木　亮、丸山　一雄、新槇　幸彦
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25560240
[Presentation] アニオン性脂質含有バブルリポソームの開発
- Author(s)
  根岸　洋一、菊池　太希、髙橋　葉子、小栗　由貴子、杉本　勝俊、森安　史典、鈴木　亮、丸山　一雄、新槇　幸彦
- Organizer
  第12回日本超音波治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25560240

1. MARUYAMA Kazuo (30130040)

# of Collaborated Projects: 10 results

# of Collaborated Products: 76 results
2. TAKAHASHI Yoko (30453806)

# of Collaborated Projects: 8 results

# of Collaborated Products: 53 results
3. ARAMAKI Yukihiko (90138959)

# of Collaborated Projects: 7 results

# of Collaborated Products: 63 results
4. TAKAGI Norio (50318193)

# of Collaborated Projects: 7 results

# of Collaborated Products: 22 results
5. SETO Kan-ichi (60064367)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. SEKIYA Hideki (70267540)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
7. YAMAMOTO Matuo (50332896)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. NOMIZU Motoyoshi (00311522)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
9. KAWASHIMA Kohtaro (20124993)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. KONDOU Toshiroh (70178416)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TAKAGAKI Yuko (60050689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. TAKIZAWA Tomoko (90260934)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 吉川大和 (20274227)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. DAIKI OMATA

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
15. HAMANO NOBUHITO

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
16. NAKAJIMA Masahiro (10338692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAMURA Masato (30236757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUZUKI RYO (90384784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. MARUYAMA TORU (90423657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. Taniguchi-Ikeda Mariko (00410738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KEIKO Ishigaki (10366304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. HARADA Risa (30736864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOSHIDA Masaru (10583750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TAKAO Keizo (80420397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 濱田良樹 (70247336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 和泉雄一 (60159803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 町頭三保 (80253897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 江本精 (80258540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 朝山章一郎 (90315755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
30. 川上浩良 (10221897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
31. TAKAYAMA Noriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
32. HONJOU Emi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
33. TSUNODA YUKA

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. MATSUO KEIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
35. MATSUKI YUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
36. TANONAKA Kouichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. MARUNOUCHI Tetsuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. KATAGIRI Fumihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
39. ISHII Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
40. OGURI Yukiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
41. SHIONO Hitomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
42. AKIYAMA Saki

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
43. MAYAMA Sayaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
44. KIKUCHI Taiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
45. ISHIMA YU

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
46. SAWADA HONOKA

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
47. SASAYAMA MIZUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
48. ODA Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NEGISHI Youichi 根岸 洋一

根岸 洋一 ネギシ ヨウイチ

NEGISHI Yoichi 根岸 陽一

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光音響と超音波応答性ナノバブルによる革新的セラノスティクスシステムの開発Principal InvestigatorOngoing

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Development of ultrasound-responsive nanobubbles containing genome editing tools and establishment of disease treatment systemPrincipal InvestigatorOngoing

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環状DNA単分子の高密度凝縮化技術による生体個体内未踏空間送達システムの創製Ongoing

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超音波応答性ナノバブルによる抗体デリバリーシステムの開発と乳がん治療戦略Principal InvestigatorOngoing

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Development of ultrasound-responsive nanobubbles containing physiologically active gas and construction of disease treatment systemPrincipal Investigator

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子宮癌肉腫幹細胞の血管ニッチを制御する治療法の開発と癌幹細胞治療への展開Ongoing

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Ultrasound-mediated gene delivery system into brain tissue by blood brain barrier targeting Bubble liposomesPrincipal Investigator

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Therapeutic systems of muscular dystrophy by morpholino oligonucleotide-loaded nanobubble and ultrasoundPrincipal Investigator

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Gene transfer system into mesenchymal stem cell by peptide-modified liposomes and ultrasound technologyPrincipal Investigator

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Low invasive therapeutic system for vascular diseases by neovascular specific liposomes containing US-contrast gasPrincipal Investigator

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NEGISHI Youichi 根岸洋一

根岸洋一ネギシヨウイチ

NEGISHI Yoichi 根岸陽一